List of works by Charles G. Drake

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

A DNA hypomethylating drug alters the tumor microenvironment and improves the effectiveness of immune checkpoint inhibitors in a mouse model of pancreatic cancer

scientific article published on 14 August 2020

A Paracrine Role for IL6 in Prostate Cancer Patients: Lack of Production by Primary or Metastatic Tumor Cells

scientific article published on 5 June 2015

A Phase I Study of Alpha-1,3-Galactosyltransferase-Expressing Allogeneic Renal Cell Carcinoma Immunotherapy in Patients with Refractory Metastatic Renal Cell Carcinoma

scientific article published on 06 September 2019

A Prospective Study of Chronic Inflammation in Benign Prostate Tissue and Risk of Prostate Cancer: Linked PCPT and SELECT Cohorts.

scientific article published on 28 July 2017

A Retrospective Analysis of the Effect on Survival of Time from Diagnosis to Neoadjuvant Chemotherapy to Cystectomy for Muscle Invasive Bladder Cancer

scientific article

A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target

scientific article published on 01 March 2020

A draft map of the human proteome

scientific article (publication date: 29 May 2014)

A human prostatic bacterial isolate alters the prostatic microenvironment and accelerates prostate cancer progression

scientific article published on February 2015

A multi-omic analysis of human naïve CD4+ T cells

scientific article published on 6 November 2015

A peripheral circulating TH1 cytokine profile is inversely associated with prostate cancer risk in CLUE II.

scientific article

A phase I study of muscadine grape skin extract in men with biochemically recurrent prostate cancer: Safety, tolerability, and dose determination

scientific article

A phase III randomized study comparing perioperative nivolumab vs. observation in patients with localized renal cell carcinoma undergoing nephrectomy (PROSPER RCC)

A role for paracrine interleukin-6 signaling in the tumor microenvironment in prostate tumor growth

scientific article published on 21 October 2018

A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells

scientific article

Abstract 1437: Prostate cancer cells up-regulate PD-L1 in response to pro-inflammatory cytokines

Adaptive Immune Resistance to Intravesical BCG in Non-Muscle Invasive Bladder Cancer: Implications for Prospective BCG-Unresponsive Trials

scientific article published on 11 November 2019

Allogeneic versus autologous blood transfusion and survival after radical prostatectomy

scientific article published on 6 March 2014

Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines

scientific article published on 22 September 2005

Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen

scientific article

Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells

scholarly article

Anti-tumor effects of endogenous prostate cancer-specific CD8 T cells in a murine TCR transgenic model

scientific article published on 14 July 2011

Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival

scientific article published on 01 June 2018

Assessment of tumoral PD-L1 expression and intratumoral CD8+ T cells in urothelial carcinoma.

scientific article

Association between variants in genes involved in the immune response and prostate cancer risk in men randomized to the finasteride arm in the Prostate Cancer Prevention Trial

scientific article published on 20 March 2017

Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II.

scientific article

Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors

scientific article

Asthma and risk of lethal prostate cancer in the Health Professionals Follow-Up Study

scientific article published on 27 February 2015

Bacteriolytic therapy can generate a potent immune response against experimental tumors

scholarly article

Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: an open-label, phase 2, multicohort study

scientific article published on 13 December 2017

Blocking Interleukin-1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multi-Dimensional Analyses

scientific article published on 04 November 2020

Blood Transfusion is Associated with Increased Perioperative Morbidity and Adverse Oncologic Outcomes in Bladder Cancer Patients Receiving Neoadjuvant Chemotherapy and Radical Cystectomy

scientific article

Breathing new life into immunotherapy: review of melanoma, lung and kidney cancer

scientific article

CD4+ T Cells Pass Through an Effector Phase During the Process of In Vivo Tolerance Induction

scientific article published on 01 April 2003

Cancer immunotherapy highlights from the 2014 ASCO Meeting

Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial

scientific article

Circulating beta-2 microglobulin and risk of cancer: the Atherosclerosis Risk in Communities Study (ARIC)

journal article published in 2016

Combinatorial Immunotherapy: PD-1 may not be LAG-ing behind any more

scientific article published on October 2012

Combined Next-generation Sequencing and Flow Cytometry Analysis for an Anti-PD-L1 Partial Responder over Time: An Exploration of Mechanisms of PD-L1 Activity and Resistance in Bladder Cancer

scientific article published on 26 February 2019

Combined local and systemic attacks

scientific article published on 01 August 2018

Combined treatment effects of radiation and immunotherapy: studies in an autochthonous prostate cancer model

scientific article published on 21 September 2013

Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model

scientific article published on 4 December 2017

Comprehensive Evaluation of Programmed Death-Ligand 1 Expression in Primary and Metastatic Prostate Cancer

scientific article published on 22 March 2018

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

scientific article published on 25 February 2015

Consequences of interleukin 1β-triggered chronic inflammation in the mouse prostate gland: Altered architecture associated with prolonged CD4+ infiltration mimics human proliferative inflammatory atrophy

scientific article published on 22 March 2019

Current immunotherapeutic strategies in prostate cancer

scientific article published on October 2007

Cutaneous Eruptions in Patients Receiving Immune Checkpoint Blockade: Clinicopathologic Analysis of the Nonlichenoid Histologic Pattern

scientific article published on 15 August 2017

Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity

scientific article published on 01 October 2007

Cutting edge: accelerated autoimmune diabetes in the absence of LAG-3

scientific article

Cyclic dinucleotides (CDNs) reversed T cells tolerance in anti-tumor immunotherapy.

scientific article published on 4 November 2015

Cyclophosphamide augments antitumor immunity: studies in an autochthonous prostate cancer model

scientific article

Cytoreductive nephrectomy for metastatic renal cell carcinoma, the ultimate urologic 'Choosing Wisely' campaign: a narrative review

scientific article published on 01 November 2020

De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute.

scientific article published on April 2016

Defining tumor resistance to PD-1 pathway blockade: recommendations from the first meeting of the SITC Immunotherapy Resistance Taskforce

scientific article published on 01 March 2020

Differential Immune Modulation With Carbon-Ion Versus Photon Therapy

scientific article published on 13 November 2020

Differential subcellular localization of the regulatory T-cell protein LAG-3 and the coreceptor CD4.

scientific article

Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody

scientific article published on 20 November 2012

Elective Nodal Irradiation Attenuates the Combinatorial Efficacy of Stereotactic Radiation Therapy and Immunotherapy

scientific article published on 13 June 2018

Eleventh Prouts Neck Meeting on Prostate Cancer: Emerging Strategies in Prostate Cancer Therapy

scientific article published on 10 October 2007

Enhancement of the T-cell armamentarium as a cell-based therapy for prostate cancer

scientific article

Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells

scientific article

Epithelial architectural destruction is necessary for bone marrow derived cell contribution to regenerating prostate epithelium

scientific article published in August 2006

Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma

scientific article published on 3 January 2013

Expression profile and in vitro blockade of programmed death-1 in human papillomavirus-negative head and neck squamous cell carcinoma

scientific article

Final Analysis of the Ipilimumab Versus Placebo Following Radiotherapy Phase III Trial in Postdocetaxel Metastatic Castration-resistant Prostate Cancer Identifies an Excess of Long-term Survivors

scientific article published on 15 August 2020

Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells

scientific article

Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

scientific article published on 4 January 2018

Glycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function

scientific article

Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+.

scientific article

Humoral Immune Response against Nontargeted Tumor Antigens after Treatment with Sipuleucel-T and Its Association with Improved Clinical Outcome

scientific article published on 3 February 2015

Hypomethylation, endogenous retrovirus expression, and interferon signaling in testicular germ cell tumors

article published in the Proceedings of the National Academy of Sciences of the United States of America

IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy

scientific article published on 27 June 2018

IMPS-31FOCAL BRAIN RADIATION INDUCES SYSTEMIC LYMPHOPENIA IN MICE.

scientific article

Immune biomarkers associated with clinical benefit from atezolizumab (MPDL3280a; anti-PD-L1) in advanced urothelial bladder cancer (UBC).

scientific article published on 4 November 2015

Immune checkpoint inhibitors: a new frontier in bladder cancer

scientific article

Immune response from STRIDE, a randomized, Phase II, open-label study of sipuleucel-T (sip-T) with concurrent vs sequential enzalutamide (enz) administration in metastatic castration-resistant prostate cancer (mCRPC).

scientific article published on 4 November 2015

Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition

scientific article published on 25 October 2019

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

scientific article published on 01 November 2018

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

scientific article published on 04 September 2018

Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma

scientific article published on 11 May 2016

Immunotherapy earns its spot in the ranks of cancer therapy

scientific article published on February 2012

Immunotherapy for prostate cancer: recent advances, lessons learned, and areas for further research

scientific article

Infectious complications in transfused patients after radical cystectomy

scientific article published on August 2016

Inflammation in Benign Prostate Tissue and Prostate Cancer in the Finasteride Arm of the Prostate Cancer Prevention Trial.

scientific article published on 29 December 2015

Inflammation in prostate carcinogenesis

scientific article published on April 2007

Inhibitors of the PD-1 Pathway in Tumor Therapy

scientific article

Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19

scientific article published on 01 April 2020

Intra-individual variation in serum C-reactive protein over 4 years: an implication for epidemiologic studies

scientific article

Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer.

scientific article published on 19 June 2018

Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial

scientific article published on 15 January 2016

LAG-3 in Cancer Immunotherapy ⬇️

scientific article published on January 1, 2011

LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems

scientific article

LAG-3 regulates plasmacytoid dendritic cell homeostasis

scientific article

LAG3 (CD223) as a cancer immunotherapy target

scientific article published on March 2017

Lenalidomide in Nonmetastatic Biochemically Relapsed Prostate Cancer: Results of a Phase I/II Double-Blinded, Randomized Study ⬇️

scientific article published on October 26, 2010

Lenalidomide modulates IL-8 and anti-prostate antibody levels in men with biochemically recurrent prostate cancer

scientific article published on 11 July 2011

Lymphocyte Activation Gene 3 (LAG-3) modulates the ability of CD4 T-cells to be suppressed in vivo

scientific article published on 5 November 2014

Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019

scientific article published on 27 January 2020

Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017.

scientific article

Markers of inflammation are associated with clinical outcomes in patients with metastatic renal cell carcinoma treated with nivolumab.

scientific article published on 4 November 2015

Mechanisms of Resistance to Immune Checkpoint Blockade: Why Does Checkpoint Inhibitor Immunotherapy Not Work for All Patients?

scientific article published on 01 January 2019

Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

scientific article

Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial

scientific article

New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31stAnnual Meeting of the Society for Immunotherapy of Cancer, 2016

scientific article

New Strategies in Bladder Cancer: A Second Coming for Immunotherapy

scientific article published on 18 December 2015

Outcomes Following Clinical Complete Response to Neoadjuvant Chemotherapy for Muscle-invasive Urothelial Carcinoma of the Bladder in Patients Refusing Radical Cystectomy

scientific article published on 12 October 2017

PD-1 blockade in renal cell carcinoma: to equilibrium and beyond

scientific article

Pembrolizumab for Treatment-Refractory Metastatic Castration-Resistant Prostate Cancer: Multicohort, Open-Label Phase II KEYNOTE-199 Study

scientific article published on 27 November 2019

Peripheral Zone Inflammation Is Not Strongly Associated With Lower Urinary Tract Symptom Incidence and Progression in the Placebo Arm of the Prostate Cancer Prevention Trial .

scientific article published on 21 June 2016

Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing

scientific article published on June 2008

Potential role of decoy B7-H4 in the pathogenesis of rheumatoid arthritis: a mouse model informed by clinical data

scientific article

Pre-radiation lymphocyte harvesting and post-radiation reinfusion in patients with newly diagnosed high grade gliomas

scientific article

Primer on tumor immunology and cancer immunotherapy

scientific article

Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study

scientific article published on 09 October 2012

Programmed Cell Death Ligand-1 Blockade in Urothelial Bladder Cancer: To Select or Not to Select

scientific article published on 25 July 2016

Prostate Cancer Cells Express More Androgen Receptor (AR) Following Androgen Deprivation, Improving Recognition by AR-Specific T Cells

scientific article

Prostate cancer

scientific article published in The Lancet

Prostate cancer immunotherapy

scientific article published on 23 June 2011

Prostate carcinogenesis: inflammatory storms

scientific article published on 16 June 2020

Putting the Pieces Together: Completing the Mechanism of Action Jigsaw for Sipuleucel-T

scientific article published on 07 March 2020

Quantitative Analysis of Immune Infiltrates in Primary Melanoma.

scientific article published on 21 February 2018

Radiotherapy augments the immune response to prostate cancer in a time-dependent manner

scientific article published on September 2008

Recent advances in immunotherapy for kidney cancer

scientific article published on April 2016

Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment

scientific article published on February 2009

Reply to Ethan B. Ludmir, Zachary R. McCaw, and Lee-Jen Wei's Letter to the Editor re: Karim Fizazi, Charles G. Drake, Tomasz M. Beer, et al. Final Analysis of the Ipilimumab Versus Placebo Following Radiotherapy Phase III Trial in Postdocetaxel Met

scientific article published on 26 October 2020

Reply: Regulatory T cells-an important target for cancer immunotherapy

scientific article published on 29 April 2014

Role of Antigen Spread and Distinctive Characteristics of Immunotherapy in Cancer Treatment

scientific article

Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells

scientific article

STAT3 signaling in CD4+ T cells is critical for the pathogenesis of chronic sclerodermatous graft-versus-host disease in a murine model

scientific article

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

scientific article (publication date: 28 June 2012)

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

scientific article

Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer

scientific article published on 4 April 2013

Sequencing of Sipuleucel-T and Androgen Deprivation Therapy in Men with Hormone-Sensitive Biochemically Recurrent Prostate Cancer: A Phase II Randomized Trial

scientific article published on 10 November 2016

Stereotactic Radiation Therapy Augments Antigen-Specific PD-1-Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen

scientific article

Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment.

scientific article published on 2 October 2017

Strain-specific induction of experimental autoimmune prostatitis (EAP) in mice

scientific article published on 5 November 2012

Subverting the B7-H1/PD-1 pathway in advanced melanoma and kidney cancer

scientific article

Summary and Recommendations from the National Cancer Institute's Clinical Trials Planning Meeting on Novel Therapeutics for Non-Muscle Invasive Bladder Cancer ⬇️

scientific article published on 27 April 2016

Summary from the First Kidney Cancer Research Summit, September 12-13, 2019: A Focus on Translational Research

scientific article published on 02 May 2020

Summary from the Kidney Cancer Association's Inaugural Think Thank: Coalition for a Cure

scientific article published on 14 November 2020

Survival, Durable Response, and Long-Term Safety in Patients With Previously Treated Advanced Renal Cell Carcinoma Receiving Nivolumab

scientific article published on 30 March 2015

Systemic depletion of lymphocytes following focal radiation to the brain in a murine model

scientific article published on 09 May 2018

T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

scientific article published on 15 March 2020

TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors.

scientific article published on 22 February 2018

Targeting PD-1 or PD-L1 in Metastatic Kidney Cancer: Combination Therapy in the First-Line Setting

scientific article published on 16 January 2020

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

scientific article published on 9 January 2012

Tc17 CD8 T cells: functional plasticity and subset diversity.

scientific article

The Immunobiology of Kidney Cancer

scientific article published on 29 October 2018

The Intratumoral Balance between Metabolic and Immunologic Gene Expression Is Associated with Anti-PD-1 Response in Patients with Renal Cell Carcinoma

scientific article published on 4 August 2016

The Landscape of Whole-genome Alterations and Pathologic Features in Genitourinary Malignancies: An Analysis of the Cancer Genome Atlas

scientific article

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of prostate carcinoma

scientific article published on 20 December 2016

The Society for Immunotherapy of Cancer perspective on regulation of interleukin-6 signaling in COVID-19-related systemic inflammatory response

scientific article published on 01 May 2020

The future of perioperative therapy in advanced renal cell carcinoma: how can we PROSPER?

scientific article published on 10 April 2019

Transcriptional profiling of tumor associated macrophages in human renal cell carcinoma reveals significant heterogeneity and opportunity for immunomodulation

scientific article published on 25 February 2020

Tumor Regression and Allograft Rejection after Administration of Anti-PD-1

scientific article published on March 2016

Tumor immune microenvironment in non-muscle-invasive urothelial carcinoma of the bladder

scientific article published on 24 April 2019

Tumor immunology and cancer immunotherapy: summary of the 2013 SITC primer

scientific article

Tumor immunology--towards a paradigm of reciprocal research

scientific article

Tumor recognition and self-recognition induce distinct transcriptional profiles in antigen-specific CD4 T cells.

scientific article

Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial

scientific article published on 24 June 2020

Variation in IL10 and other genes involved in the immune response and in oxidation and prostate cancer recurrence

scientific article

Variation in genes involved in the immune response and prostate cancer risk in the placebo arm of the Prostate Cancer Prevention Trial

scientific article

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