List of works - Inna A Belyantseva

A null mutation of mouse Kcna10 causes significant vestibular and mild hearing dysfunction.

scientific article

Actin at stereocilia tips is regulated by mechanotransduction and ADF/cofilin

scientific article published on 22 December 2020

Actin in hair cells and hearing loss ⬇️

scientific article published on December 13, 2011

Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing

scientific article

Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48.

scientific article

Auditory mechanotransduction in the absence of functional myosin-XVa.

scientific article published on 14 September 2006

Autosomal-Recessive Hearing Impairment Due to Rare Missense Variants within S1PR2

scientific article published on 19 January 2016

CDC14A Phosphatase is Essential for Hearing and Male Fertility in Mouse and Human.

scientific article published on 23 December 2017

Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration

scientific article

Deafness and stria vascularis defects in S1P2 receptor-null mice.

scientific article

Expression of prestin, a membrane motor protein, in the mammalian auditory and vestibular periphery.

scientific article

Functional null mutations of MSRB3 encoding methionine sulfoxide reductase are associated with human deafness DFNB74

scientific article

Gamma-actin is required for cytoskeletal maintenance but not development

scientific article

Gene expression profile of the mouse organ of Corti at the onset of hearing

scientific article published in June 2004

Genetic insights into the morphogenesis of inner ear hair cells.

scientific article published on July 2004

Harnessing molecular motors for nanoscale pulldown in live cells.

scientific article

ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells

scientific article

Molecular basis of DFNB73: mutations of BSND can cause nonsyndromic deafness or Bartter syndrome.

scientific article published on 30 July 2009

Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells

scientific article

Mouse Models of Human Pathogenic Variants of TBC1D24 Associated with Non-Syndromic Deafness DFNB86 and DFNA65 and Syndromes Involving Deafness

scientific article published on 24 September 2020

Mutation spectrum of MYO7A and evaluation of a novel nonsyndromic deafness DFNB2 allele with residual function

scientific article published in April 2008

Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse

scientific journal article

Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice

scientific article

Mutations of LRTOMT, a fusion gene with alternative reading frames, cause nonsyndromic deafness in humans

scientific article

Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle ⬇️

scientific article published on November 10, 2003

Myosins and Hearing

scientific article published on 01 January 2020

PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23 ⬇️

scientific article published on October 21, 2003

Phenotypic variability of CLDN14 mutations causing DFNB29 hearing loss in the Pakistani population ⬇️

scientific article published on December 13, 2012

Recent advances in the understanding of syndromic forms of hearing loss

scientific article

Signatures from tissue-specific MPSS libraries identify transcripts preferentially expressed in the mouse inner ear.

scientific article

Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development

scientific journal article

Stereocilia: the long and the short of it ⬇️

scientific article published on November 1, 2003

TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing

scientific article published on 20 June 2019

Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79

scientific article

The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing

scientific article

The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy

scientific article published on 01 May 2019

The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15

scientific article published on 01 June 2006

Tricellulin deficiency affects tight junction architecture and cochlear hair cells.

scientific article

Tricellulin is a tight-junction protein necessary for hearing

scientific article

Twinfilin 2 regulates actin filament lengths in cochlear stereocilia

scientific article

List of works by Inna A Belyantseva

A null mutation of mouse Kcna10 causes significant vestibular and mild hearing dysfunction.

Actin at stereocilia tips is regulated by mechanotransduction and ADF/cofilin

Actin in hair cells and hearing loss ⬇️

Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing

Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48.

Auditory mechanotransduction in the absence of functional myosin-XVa.

Autosomal-Recessive Hearing Impairment Due to Rare Missense Variants within S1PR2

CDC14A Phosphatase is Essential for Hearing and Male Fertility in Mouse and Human.

Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration

Deafness and stria vascularis defects in S1P2 receptor-null mice.

Expression of prestin, a membrane motor protein, in the mammalian auditory and vestibular periphery.

Functional null mutations of MSRB3 encoding methionine sulfoxide reductase are associated with human deafness DFNB74

Gamma-actin is required for cytoskeletal maintenance but not development

Gene expression profile of the mouse organ of Corti at the onset of hearing

Genetic insights into the morphogenesis of inner ear hair cells.

Harnessing molecular motors for nanoscale pulldown in live cells.

ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells

Molecular basis of DFNB73: mutations of BSND can cause nonsyndromic deafness or Bartter syndrome.

Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells

Mouse Models of Human Pathogenic Variants of TBC1D24 Associated with Non-Syndromic Deafness DFNB86 and DFNA65 and Syndromes Involving Deafness

Mutation spectrum of MYO7A and evaluation of a novel nonsyndromic deafness DFNB2 allele with residual function

Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse

Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice

Mutations of LRTOMT, a fusion gene with alternative reading frames, cause nonsyndromic deafness in humans

Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle ⬇️

Myosins and Hearing

PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23 ⬇️

Phenotypic variability of CLDN14 mutations causing DFNB29 hearing loss in the Pakistani population ⬇️

Recent advances in the understanding of syndromic forms of hearing loss

Signatures from tissue-specific MPSS libraries identify transcripts preferentially expressed in the mouse inner ear.

Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development

Stereocilia: the long and the short of it ⬇️

TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing

Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79

The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing

The phenotypic landscape of a Tbc1d24 mutant mouse includes convulsive seizures resembling human early infantile epileptic encephalopathy

The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15

Tricellulin deficiency affects tight junction architecture and cochlear hair cells.

Tricellulin is a tight-junction protein necessary for hearing

Twinfilin 2 regulates actin filament lengths in cochlear stereocilia