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List of works by Evan Y Snyder

"Reprogram Enablement" as an Assay for Identifying Early Oncogenic Pathways by Their Ability to Allow Neoplastic Cells to Reacquire an Epiblast State

scientific article published on 04 August 2020

A Biomarker for Predicting Responsiveness to Stem Cell Therapy Based on Mechanism-of-Action: Evidence from Cerebral Injury

scientific article published on 01 May 2020

A Human Embryonic Stem Cell-Derived Clonal Progenitor Cell Line with Chondrogenic Potential and Markers of Craniofacial Mesenchyme ⬇️

scientific article published on April 23, 2012

A Review and Rationale for the Use of Cellular Transplantation as a Therapeutic Strategy for Traumatic Brain Injury

A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes.

scientific article published on 7 June 2007

A quantitative, multi-national and multi-stakeholder assessment of barriers to the adoption of cell therapies.

scientific article

A review and rationale for the use of cellular transplantation as a therapeutic strategy for traumatic brain injury

scientific article

A role for stem cell biology in the physiological and pathological aspects of aging

scientific article published in September 2005

A safer stem cell: on guard against cancer

scientific article

Aberrant production of tenascin-C in globoid cell leukodystrophy alters psychosine-induced microglial functions

scientific article

Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation

scientific article

Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: evidence from the effect of hypoxia-ischemia in the CNS on clonal "reporter" neural stem cells

scientific article

Adhesive interactions between human neural stem cells and inflamed human vascular endothelium are mediated by integrins

scientific article

Automated Core–Penumbra Quantification in Neonatal Ischemic Brain Injury ⬇️

scientific article published on August 29, 2012

Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.

scholarly article

Beyond fraud--stem-cell research continues

scientific article published on January 2006

Brain tumor stem cells and the tumor microenvironmen

scientific article published on January 2008

Can science resolve the ethical impasse in stem cell research?

scientific article published in April 2006

Caspase-mediated cell death predominates following engraftment of neural progenitor cells into traumatically injured rat brain

scientific article published on 23 November 2005

Chemical mutagenesis of a GPCR ligand: Detoxifying "inflammo-attraction" to direct therapeutic stem cell migration

scientific article published on 20 November 2020

Combined total proteomic and phosphoproteomic analysis of human pluripotent stem cells

scientific article

Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host

scientific article

Constitutive EGFR signaling confers a motile phenotype to neural stem cells

scientific article

Countermeasures for preventing and treating opioid overdose

scientific article published on 28 October 2020

Cross-talk between stem cells and the dysfunctional brain is facilitated by manipulating the niche: evidence from an adhesion molecule

scientific article

Cryopreservation by slow cooling with DMSO diminished production of Oct-4 pluripotency marker in human embryonic stem cells

scientific article published on 12 July 2006

Culture and manipulation of neural stem cells.

scientific article

Culture system for rodent and human oligodendrocyte specification, lineage progression, and maturation

scientific article published in September 2009

DMSO-Free Programmed Cryopreservation of Fully Dissociated and Adherent Human Induced Pluripotent Stem Cells

scientific article

Defining Conditions for Sustaining Epiblast Pluripotence Enables Direct Induction of Clinically-Suitable Human Myocardial Grafts from Biologics-Free Human Embryonic Stem Cells ⬇️

scientific article published on April 25, 2012

Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology

scientific article

Derivation of vasculature from embryonic stem cells

scientific article

Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human-Induced Pluripotent Stem Cells

scientific article published on 01 September 2020

Deriving dopaminergic neurons for clinical use. A practical approach

scientific article

Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord

scientific article published on November 2004

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

scientific article

Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells

scholarly article

Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotion

scientific article published on 24 February 2020

Dorsomorphin Promotes Human Embryonic Stem Cell Self‐Renewal ⬇️

scientific article published on 07 March 2011

Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness

scientific article published on 01 August 2019

Early acquisition of neural crest competence during hESCs neuralization

scientific article

Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction ⬇️

scientific article published on November 3, 2011

Efficient derivation of human neuronal progenitors and neurons from pluripotent human embryonic stem cells with small molecule induction

scientific article published on 28 October 2011

Electron microscopy and lac-Z labeling

scientific article published on 01 January 2002

Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards.

scientific article

Experimental traumatic brain injury modulates the survival, migration, and terminal phenotype of transplanted epidermal growth factor receptor-activated neural stem cells.

scientific article

Exploring common ground in the stem cell ethical debate--a perspective for scientists: introduction to this special issue of stem cell reviews

scientific article published in December 2005

Expression profile of an operationally-defined neural stem cell clone.

scientific article published on August 2005

Fate of multipotent neural precursor cells transplanted into mouse retina selectively depleted of retinal ganglion cells.

scientific article published in March 2004

Finding a new purpose for old drugs

scientific article

Functional Multipotency of Stem Cells: A Conceptual Review of Neurotrophic Factor-Based Evidence and Its Role in Translational Research ⬇️

scientific article published on December 1, 2011

Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells

scientific article

Gene therapy: can neural stem cells deliver?

scientific article

Generating iPSCs: translating cell reprogramming science into scalable and robust biomanufacturing strategies.

scientific article published in January 2015

Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation

scientific article published on 01 September 2020

Generation, Characterization, and Transplantation of Immortalized Human Neural Crest Stem Cells

Generation, Expansion, and Differentiation of Human Induced Pluripotent Stem Cells (hiPSCs) Derived From the Umbilical Cords of Newborns

scientific article published on 16 May 2014

Genetic modification of neural stem cells

scientific article published on 05 February 2008

Genetic programs and responses of neural stem/progenitor cells during demyelination: potential insights into repair mechanisms in multiple sclerosis

scientific article

HG-13SOX9 AS A DOWN-STREAM TARGET IN RAS/MEK-DRIVEN PEDIATRIC GLIOMA.

scientific article published on 21 April 2015

Homing of neural stem cells from the venous compartment into a brain infarct does not involve conventional interactions with vascular endothelium

scientific article

Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease

scientific article published on 14 February 2008

Human neural stem cells rapidly ameliorate symptomatic inflammation in early-stage ischemic-reperfusion cerebral injury

scientific article published on 23 November 2014

Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target.

scientific article

Human neurospheres derived from the fetal central nervous system are regionally and temporally specified but are not committed

scientific article published on 22 May 2006

Identification of human embryonic progenitor cell targeting peptides using phage display

scientific article

Immortalization of human neural stem cells with the c-myc mutant T58A.

scientific article

Immunomodulatory neural stem cells for brain tumour therapy

scientific article published on December 2006

Implications and limitations of cellular reprogramming for psychiatric drug development

scientific article

Important precautions when deriving patient-specific neural elements from pluripotent cells

scientific article

In vivo tracking of neural progenitor cell migration to glioblastomas

scientific article

Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells

scientific article published on 27 February 2020

Inflammation as a matchmaker: revisiting cell fusion.

scientific article

Injection of mouse and human neural stem cells into neonatal Niemann-Pick A model mice

scientific article published on 9 January 2007

Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non-autonomous disorders: evidence from a mouse model of Krabbe leukodystrophy

scientific article published in June 2006

Isolation of amniotic stem cell lines with potential for therapy

scientific article

Large animal models are critical for rationally advancing regenerative therapies

scientific article

Laser-assisted generation of human induced pluripotent stem cells

scientific article

Limitations in brain repair

scientific article published in September 2002

Long-term multilayer adherent network (MAN) expansion, maintenance, and characterization, chemical and genetic manipulation, and transplantation of human fetal forebrain neural stem cells

scientific article

Long‐term magnetic resonance imaging of stem cells in neonatal ischemic injury ⬇️

scientific article published on November 22, 2010

MMP‐3 mediates psychosine‐induced globoid cell formation: Implications for leukodystrophy pathology ⬇️

scientific article published on February 13, 2013

Maintaining and engineering neural stem cells for delivery of genetically encoded therapy to brain tumors

scientific article published on January 2009

Microarray-based transcriptional and epigenetic profiling of matrix metalloproteinases, collagens, and related genes in cancer

scientific article

Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury

scholarly article

Modeling Complex Neurological Diseases with Stem Cells: A Study of Bipolar Disorder

scientific article published on 01 January 2018

Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells ⬇️

scientific article published on June 29, 2011

Multimodal Actions of Neural Stem Cells in a Mouse Model of ALS: A Meta-Analysis ⬇️

scientific article published on December 19, 2012

Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents

scholarly article

Neural Stem Cell Tumorigenicity and Biodistribution Assessment for Phase I Clinical Trial in Parkinson's Disease

scientific article published on 30 September 2016

Neural Stem Cells Derived From Human Parthenogenetic Stem Cells Engraft and Promote Recovery in a Nonhuman Primate Model of Parkinsons Disease

scientific article

Neural precursor cell lines promote neurite branching

scientific article

Neural progenitor cell transplantation and imaging in a large animal model

article

Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury

scientific article published on April 2006

Neural stem cell biology may be well suited for improving brain tumor therapies.

scientific article

Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida

scientific article published on 25 July 2008

Neural stem cell implantation extends life in Niemann-Pick C1 mice

scientific article

Neural stem cell transplant survival in brains of mice: assessing the effect of immunity and ischemia by using real-time bioluminescent imaging

scientific article published on December 2006

Neural stem cell transplantation benefits a monogenic neurometabolic disorder during the symptomatic phase of disease

scientific article published on September 2009

Neural stem cell transplantation in mouse brain

scientific article published in January 2008

Neural stem cells and their manipulation

scientific article published on January 2006

Neural stem cells as novel cancer therapeutic vehicles

scientific article

Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons

scientific article

Neural stem cells for CNS repair: state of the art and future directions.

scientific article

Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures.

scientific article published in January 2005

Neural stem cells injected into the sound-damaged cochlea migrate throughout the cochlea and express markers of hair cells, supporting cells, and spiral ganglion cells

scientific article

Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: Evidence from engraftment of Neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury

scientific article published on 22 May 2006

Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors

scientific article published on November 2004

Neural stem cells rescue nervous purkinje neurons by restoring molecular homeostasis of tissue plasminogen activator and downstream targets.

scientific article published in July 2006

Neural stem cells spontaneously express dopaminergic traits after transplantation into the intact or 6-hydroxydopamine-lesioned rat.

scientific article published in September 2002

Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli

scientific article

Neural stem/progenitor cells modulate immune responses by suppressing T lymphocytes with nitric oxide and prostaglandin E2.

scientific article

Neuroimaging as a basis for rational stem cell therapy

scientific article

Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption.

scientific article

Nna1 gene deficiency triggers Purkinje neuron death by tubulin hyperglutamylation and ER dysfunction

scientific article published on 02 October 2020

Nna1 mediates Purkinje cell dendritic development via lysyl oxidase propeptide and NF-κB signaling

scientific article published on October 2010

Novel Bivalent and D-Peptide Ligands of CXCR4 Mobilize Hematopoietic Progenitor Cells to the Blood in C3H/HeJ Mice.

scientific article published on 11 July 2018

Optical imaging of progenitor cell homing to patient‐derived tumors ⬇️

scientific article published on November 1, 2012

Overexpression of Basic Helix-Loop-Helix Transcription Factors Enhances Neuronal Differentiation of Fetal Human Neural Progenitor Cells in Various Ways ⬇️

scientific article published on July 18, 2011

Patents on Technologies of Human Tissue and Organ Regeneration from Pluripotent Human Embryonic Stem Cells ⬇️

scientific article published on January 1, 2011

Phosphoproteomic Analysis: An Emerging Role in Deciphering Cellular Signaling in Human Embryonic Stem Cells and Their Differentiated Derivatives ⬇️

scientific article published on March 1, 2012

Phosphoproteomic analysis of human embryonic stem cells

scientific article published in August 2009

Physical activity-mediated functional recovery after spinal cord injury: potential roles of neural stem cells

scientific article published on November 2006

Preparation of autogenic human feeder cells for growth of human embryonic stem cells.

scientific article published in March 2008

Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.

scientific article

Proof of concept studies exploring the safety and functional activity of human parthenogenetic-derived neural stem cells for the treatment of Parkinson's disease

scientific article published on 24 March 2015

Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator

scholarly article

Quantitative Analysis of Human Pluripotency and Neural Specification by In-Depth (Phospho)Proteomic Profiling

scientific article published on 23 August 2016

Quantitative assessment of barriers to the clinical development and adoption of cellular therapies: A pilot study

scientific article

Quo vadis brain repair? A long axonal journey in the adult CNS.

scientific article published on October 2007

Realistic prospects for stem cell therapeutics

scientific article published on January 2003

Reality and immortality--neural stem cells for therapies

scientific article published in March 2004

Reduced-representation Phosphosignatures Measured by Quantitative Targeted MS Capture Cellular States and Enable Large-scale Comparison of Drug-induced Phenotypes

scientific article

Regional energy metabolism following short-term neural stem cell transplantation into the injured spinal cord

scientific article published on January 2004

Repair of cartilage defects in arthritic tissue with differentiated human embryonic stem cells.

scientific article published on 19 October 2013

Reparative effects of neural stem cells in neonatal rats with hypoxic-ischemic injury are not influenced by host sex

scientific article

Reversal of Surfactant Protein B Deficiency in Patient Specific Human Induced Pluripotent Stem Cell Derived Lung Organoids by Gene Therapy

scientific article published on 17 September 2019

Role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in migration of neural progenitor cells toward glial tumors.

scientific article

STEM-11. A MAPK-DRIVEN miR-124-SOX9 AXIS IS CRITICAL FOR STEM CELL MAINTENANCE, PROGRESSION, AND THERAPY-RESISTANCE IN GLIOBLASTOMA

article published in 2017

Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency

scientific article

Seeding neural stem cells on scaffolds of PGA, PLA, and their copolymers

scientific article

Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell

scientific article

Severe Hypoxia: Consequences to Neural Stem Cells and Neurons

scientific article published on January 2011

Special feature on stem cells: current research and future prospects

scientific article published on 15 November 2013

Special issue on stem cells: "the end of the beginning".

scientific article

Special issue: the intersection of stem/progenitor cell biology and hypoxic-ischemic cerebral injury/stroke

scientific article published in May 2006

Stem Cell Composition of Umbilical Cord Blood Following Milking Compared with Delayed Clamping of the Cord Appears Better Suited for Promoting Hematopoiesis

scientific article published on 27 August 2019

Stem Cells and Spinal Cord Repair ⬇️

scientific article published on May 17, 2012

Stem cell-mediated regeneration of the intervertebral disc: cellular and molecular challenge

scientific article published on January 2008

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease.

scientific article

Stem cells: cross-talk and developmental programs

scientific article

Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system

scientific article published on April 2004

Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells.

scientific article published on 14 December 2015

The dynamics of long-term transgene expression in engrafted neural stem cells

scientific article published on July 2009

The evolution of stem cells, disease modeling, and drug discovery for neurological disorders

scientific article published on 05 February 2020

The implementation of novel collaborative structures for the identification and resolution of barriers to pluripotent stem cell translation.

scientific article

The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue

scientific article

The intricate dance between repair and inflammation: introduction to special issue

scientific article published on 15 May 2011

The leading edge of stem cell therapeutics

scientific article

The risk of putting something where it does not belong: Mesenchymal stem cells produce masses in the brain ⬇️

scientific article published on March 21, 2011

The state of the art in stem cell biology and regenerative medicine: the end of the beginning

scientific article published on 11 October 2017

The transcriptional network for mesenchymal transformation of brain tumours.

scientific article

Therapeutic effects of clenbuterol in a murine model of amyotrophic lateral sclerosis

scientific article published on 18 January 2006

Three-dimensional scaffolding to investigate neuronal derivatives of human embryonic stem cells ⬇️

scientific article published on October 1, 2012

Tissue plasminogen activator regulates Purkinje neuron development and survival ⬇️

scientific article published on May 14, 2013

Transplanted clonal neural stem-like cells respond to remote photic stimulation following incorporation within the suprachiasmatic nucleus

scientific article published on April 2002

Transplanted neural stem cells survive, differentiate, and improve neurological motor function after experimental traumatic brain injury

scientific article published on October 2002

Two cells are better than one: optimizing stem cell survival by co-grafting "helper" cells that offer regulated trophic support.

scientific article published on 12 July 2013

Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2

scientific article published on 24 November 2020

hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature

scientific article published on 21 May 2015

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