List of works - Paul S. Burgoyne

A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse

scientific journal article

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits.

scientific article published in October 2002

A new deletion of the mouse Y chromosome long arm associated with the loss of Ssty expression, abnormal sperm development and sterility

scientific article

A primer on the use of mouse models for identifying direct sex chromosome effects that cause sex differences in non-gonadal tissues

scientific article

A protein encoded by a member of the multicopy Ssty gene family located on the long arm of the mouse Y chromosome is expressed during sperm development.

scientific article published in January 2004

A yin-yang effect between sex chromosome complement and sex hormones on the immune response

scientific article

Analysis of sex differences in EGC imprinting

scientific article published in April 2004

Are XX and XY brain cells intrinsically different?

scientific article published on January 2004

BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation.

scientific article published in December 2004

Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attention.

scientific article published on 28 February 2009

Correction to: Identification of novel Y chromosome encoded transcripts by testis transcriptome analysis of mice with deletions of the Y chromosome long arm

scientific article published on 09 August 2019

Correction: A Genetic Basis for a Postmeiotic X Versus Y Chromosome Intragenomic Conflict in the Mouse

scientific article published on 22 July 2019

Deficiency in mouse Y chromosome long arm gene complement is associated with sperm DNA damage

scientific article

Deficiency in the multicopy Sycp3-like X-linked genes Slx and Slxl1 causes major defects in spermatid differentiation

scientific journal article

Deletions on mouse Yq lead to upregulation of multiple X- and Y-linked transcripts in spermatids

scientific article published on 8 August 2005

Deletions on mouse Yq lead to upregulation of multiple X- and Y-linked transcripts in spermatids

scientific article published on 01 January 2020

Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis

scientific article published on 30 June 2017

Effects of Sex Chromosome Dosage on Placental Size in Mice1 ⬇️

scientific article published on April 16, 2003

Effects on fear reactivity in XO mice are due to haploinsufficiency of a non-PAR X gene: implications for emotional function in Turner's syndrome

scientific article published on 6 July 2004

Evidence that meiotic sex chromosome inactivation is essential for male fertility.

scientific article published on 18 November 2010

Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX/XMR

scientific journal article

Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation

scientific article published on July 2008

H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis

scientific article

Heterochromatin and tri-methylated lysine 20 of histone H4 in animals

scientific article

Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals

scientific article

Human and mouse ZFY genes produce a conserved testis-specific transcript encoding a zinc finger protein with a short acidic domain and modified transactivation potential.

scientific article

Identification of novel Y chromosome encoded transcripts by testis transcriptome analysis of mice with deletions of the Y chromosome long arm

scientific article

Identification of the immunodominant HY H2-D(k) epitope and evaluation of the role of direct and indirect antigen presentation in HY responses

scientific article

Live offspring from mice lacking the Y chromosome long arm gene complement

scientific article

Localisation of histone macroH2A1.2 to the XY-body is not a response to the presence of asynapsed chromosome axes

scientific article published in January 2004

Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes

scientific journal article

Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist

scientific article

Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Head Remodelling and Sperm Tail Development

scientific article

Mouse Y-linked Zfy1 and Zfy2 are expressed during the male-specific interphase between meiosis I and meiosis II and promote the 2nd meiotic division

scientific article

Pachytene asynapsis drives meiotic sex chromosome inactivation and leads to substantial postmeiotic repression in spermatids.

scientific article published in April 2006

Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study

scientific article

Recombination between the mouse Y chromosome short arm and an additional Y short arm-derived chromosomal segment attached distal to the X chromosome PAR

scientific article

Sex chromosome complement and gonadal sex influence aggressive and parental behaviors in mice.

scientific article

Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes

scientific article published in February 2008

Sex differences in sex chromosome gene expression in mouse brain

scientific article published in June 2002

Sex-specific differences in meiotic chromosome segregation revealed by dicentric bridge resolution in mice.

scientific article

Sexual Dimorphism in Mammalian Autosomal Gene Regulation Is Determined Not Only by Sry but by Sex Chromosome Complement As Well ⬇️

scientific article published on September 14, 2010

Silencing of unsynapsed meiotic chromosomes in the mouse

scientific article published on 5 December 2004

Spermatid Development in XO Male Mice With Varying Y Chromosome Short-Arm Gene Content: Evidence for a Y Gene Controlling the Initiation of Sperm Morphogenesis

scientific article published on 01 April 2020

Spermatid development in XO male mice with varying Y chromosome short-arm gene content: evidence for a Y gene controlling the initiation of sperm morphogenesis

scientific article

Steroid sulfatase-deficient mice exhibit endophenotypes relevant to attention deficit hyperactivity disorder.

scientific article published on July 2011

Surveillance of different recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical developmental stage

scientific article

The Atypical Chemokine Receptor Ackr2 Constrains NK Cell Migratory Activity and Promotes Metastasis

scientific article published on 29 August 2018

The Y-encoded gene zfy2 acts to remove cells with unpaired chromosomes at the first meiotic metaphase in male mice

scientific article

The consequences of asynapsis for mammalian meiosis

scientific article published on March 2009

The effects of deletions of the mouse Y chromosome long arm on sperm function--intracytoplasmic sperm injection (ICSI)-based analysis.

scientific article

The expression of Y-linked Zfy2 in XY mouse oocytes leads to frequent meiosis 2 defects, a high incidence of subsequent early cleavage stage arrest and infertility.

scientific article published on February 2014

The management of DNA double-strand breaks in mitotic G2, and in mammalian meiosis viewed from a mitotic G2 perspective

scientific article published on October 2007

The multi-copy mouse gene Sycp3-like Y-linked (Sly) encodes an abundant spermatid protein that interacts with a histone acetyltransferase and an acrosomal protein

scientific journal article

The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis

scientific article

Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome

scientific article

Variably protease-sensitive prionopathy, a unique prion variant with inefficient transmission properties

scientific article

X-linked imprinting: effects on brain and behaviour

scientific article

X-monosomy effects on visuospatial attention in mice: a candidate gene and implications for Turner syndrome and attention deficit hyperactivity disorder.

scientific article published on 8 December 2006

Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice

scientific article

Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes

scientific article

List of works by Paul S. Burgoyne

A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits.

A new deletion of the mouse Y chromosome long arm associated with the loss of Ssty expression, abnormal sperm development and sterility

A primer on the use of mouse models for identifying direct sex chromosome effects that cause sex differences in non-gonadal tissues

A protein encoded by a member of the multicopy Ssty gene family located on the long arm of the mouse Y chromosome is expressed during sperm development.

A yin-yang effect between sex chromosome complement and sex hormones on the immune response

Analysis of sex differences in EGC imprinting

Are XX and XY brain cells intrinsically different?

BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation.

Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attention.

Correction to: Identification of novel Y chromosome encoded transcripts by testis transcriptome analysis of mice with deletions of the Y chromosome long arm

Correction: A Genetic Basis for a Postmeiotic X Versus Y Chromosome Intragenomic Conflict in the Mouse

Deficiency in mouse Y chromosome long arm gene complement is associated with sperm DNA damage

Deficiency in the multicopy Sycp3-like X-linked genes Slx and Slxl1 causes major defects in spermatid differentiation

Deletions on mouse Yq lead to upregulation of multiple X- and Y-linked transcripts in spermatids

Deletions on mouse Yq lead to upregulation of multiple X- and Y-linked transcripts in spermatids

Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis

Effects of Sex Chromosome Dosage on Placental Size in Mice1 ⬇️

Effects on fear reactivity in XO mice are due to haploinsufficiency of a non-PAR X gene: implications for emotional function in Turner's syndrome

Evidence that meiotic sex chromosome inactivation is essential for male fertility.

Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX/XMR

Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation

H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis

Heterochromatin and tri-methylated lysine 20 of histone H4 in animals

Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals

Human and mouse ZFY genes produce a conserved testis-specific transcript encoding a zinc finger protein with a short acidic domain and modified transactivation potential.

Identification of novel Y chromosome encoded transcripts by testis transcriptome analysis of mice with deletions of the Y chromosome long arm

Identification of the immunodominant HY H2-D(k) epitope and evaluation of the role of direct and indirect antigen presentation in HY responses

Live offspring from mice lacking the Y chromosome long arm gene complement

Localisation of histone macroH2A1.2 to the XY-body is not a response to the presence of asynapsed chromosome axes

Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes

Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist

Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Head Remodelling and Sperm Tail Development

Mouse Y-linked Zfy1 and Zfy2 are expressed during the male-specific interphase between meiosis I and meiosis II and promote the 2nd meiotic division

Pachytene asynapsis drives meiotic sex chromosome inactivation and leads to substantial postmeiotic repression in spermatids.

Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study

Recombination between the mouse Y chromosome short arm and an additional Y short arm-derived chromosomal segment attached distal to the X chromosome PAR

Sex chromosome complement and gonadal sex influence aggressive and parental behaviors in mice.

Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes

Sex differences in sex chromosome gene expression in mouse brain

Sex-specific differences in meiotic chromosome segregation revealed by dicentric bridge resolution in mice.

Sexual Dimorphism in Mammalian Autosomal Gene Regulation Is Determined Not Only by Sry but by Sex Chromosome Complement As Well ⬇️

Silencing of unsynapsed meiotic chromosomes in the mouse

Spermatid Development in XO Male Mice With Varying Y Chromosome Short-Arm Gene Content: Evidence for a Y Gene Controlling the Initiation of Sperm Morphogenesis

Spermatid development in XO male mice with varying Y chromosome short-arm gene content: evidence for a Y gene controlling the initiation of sperm morphogenesis

Steroid sulfatase-deficient mice exhibit endophenotypes relevant to attention deficit hyperactivity disorder.

Surveillance of different recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical developmental stage

The Atypical Chemokine Receptor Ackr2 Constrains NK Cell Migratory Activity and Promotes Metastasis

The Y-encoded gene zfy2 acts to remove cells with unpaired chromosomes at the first meiotic metaphase in male mice

The consequences of asynapsis for mammalian meiosis

The effects of deletions of the mouse Y chromosome long arm on sperm function--intracytoplasmic sperm injection (ICSI)-based analysis.

The expression of Y-linked Zfy2 in XY mouse oocytes leads to frequent meiosis 2 defects, a high incidence of subsequent early cleavage stage arrest and infertility.

The management of DNA double-strand breaks in mitotic G2, and in mammalian meiosis viewed from a mitotic G2 perspective

The multi-copy mouse gene Sycp3-like Y-linked (Sly) encodes an abundant spermatid protein that interacts with a histone acetyltransferase and an acrosomal protein

The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis

Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome

Variably protease-sensitive prionopathy, a unique prion variant with inefficient transmission properties

X-linked imprinting: effects on brain and behaviour

X-monosomy effects on visuospatial attention in mice: a candidate gene and implications for Turner syndrome and attention deficit hyperactivity disorder.

Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice

Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes