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List of works by Claus Kremoser

A novel principle for partial agonism of liver X receptor ligands. Competitive recruitment of activators and repressors

scientific article

Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis.

scientific article published on 12 June 2017

Dietary α-tocopherol and atorvastatin reduce high-fat-induced lipid accumulation and down-regulate CD36 protein in the liver of guinea pigs

scientific article published on 20 February 2014

FXR Controls the Tumor Suppressor NDRG2 and FXR Agonists Reduce Liver Tumor Growth and Metastasis in an Orthotopic Mouse Xenograft Model ⬇️

scientific article published on October 9, 2012

Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol

scientific article

Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice

scientific article published on 5 January 2017

Knocking on FXR's door: the "hammerhead"-structure series of FXR agonists - amphiphilic isoxazoles with potent in vitro and in vivo activities

scientific article

Nonsteroidal FXR Ligands: Current Status and Clinical Applications

scientific article published on 01 January 2019

Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties

scientific article published on 24 May 2016

Panning for SNuRMs: using cofactor profiling for the rational discovery of selective nuclear receptor modulators.

scientific article

Synthesis and pharmacological validation of a novel series of non-steroidal FXR agonists

scientific article published on 19 June 2010

Synthetic farnesoid X receptor agonists induce high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein transgenic low-density lipoprotein receptor (-/-)

scientific article published on 23 August 2012

The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction

scientific article published on 16 December 2016

The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine-rich glycoprotein

scientific article

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