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List of works by Jean-Louis Mege

A Fast and Reliable Method to Isolate Human Placental Macrophages

scientific article published on 24 May 2019

A granulocytic signature identifies COVID-19 and its severity

scientific article published on 17 September 2020

A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus

scientific article

A transcriptional signature associated with non-Hodgkin lymphoma in the blood of patients with Q fever

scientific article published on 10 June 2019

Activation and proteasomal degradation of rho GTPases by cytotoxic necrotizing factor-1 elicit a controlled inflammatory response

scientific article published on 19 May 2004

Adipose tissue serves as a reservoir for recrudescent Rickettsia prowazekii infection in a mouse model.

scientific article

Ameobal pathogen mimivirus infects macrophages through phagocytosis

scientific article

An evaluation of the effects of Lactobacillus ingluviei on body weight, the intestinal microbiome and metabolism in mice

scientific article published on 18 October 2011

An experimental mouse model to establish Tropheryma whipplei as a diarrheal agent

scientific article published in July 2011

Analysis and Characterization of Immune Cells and Their Activation Status by Whole-Cell MALDI-TOF Mass Spectrometry

scientific article published on 01 January 2019

Anti-cardiolipin IgG autoantibodies are an independent risk factor of COVID-19 severity

scientific article published on 21 June 2020

Antiangiogenic effect of erythromycin: an in vitro model of Bartonella quintana infection

scientific article

Antimicrobial capacity of the freshwater planarians against S. aureus is under the control of Timeless

scientific article published on 4 January 2017

B-cell non-Hodgkin lymphoma linked to Coxiella burnetii.

scientific article published on 13 October 2015

Bartonella quintana bacteremia and overproduction of interleukin-10: model of bacterial persistence in homeless people

scientific article published on 24 February 2003

CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1-/- cells

scientific article

COVID-19 gender susceptibility and outcomes: A systematic review

scientific article published on 03 November 2020

CXCL9, a promising biomarker in the diagnosis of chronic Q fever

scientific article published on 9 August 2017

Changing the paradigm of IFN-γ at the interface between innate and adaptive immunity: Macrophage-derived IFN-γ

scientific article published on 12 June 2020

Chronic hepatitis E virus infection is specifically associated with an interferon-related transcriptional program

scientific article published on 16 October 2012

Cigarette smoke extract interferes with placenta macrophage functions: A new mechanism to compromise placenta functions?

scientific article published on 16 April 2018

Circadian Rhythm Disruption and Sepsis in Severe Trauma Patients

scientific article published on 01 July 2019

Circadian disruption of core body temperature in trauma patients: a single-center retrospective observational study

scientific article published on 06 January 2020

Circulating matrix metalloproteinases in infective endocarditis: a possible marker of the embolic risk

scientific article

Correction: Adipose Tissue Serves as a Reservoir for Recrudescent Rickettsia prowazekii Infection in a Mouse Model

scientific article published in PLoS ONE

Coxiella burnetii Induces Inflammatory Interferon-Like Signature in Plasmacytoid Dendritic Cells: A New Feature of Immune Response in Q Fever

scientific article published on 27 June 2016

Coxiella burnetii avoids macrophage phagocytosis by interfering with spatial distribution of complement receptor 3.

scientific article published on April 2003

Coxiella burnetii infection in C57BL/6 mice aged 1 or 14 months.

scientific article

Coxiella burnetii lipopolysaccharide blocks p38α-MAPK activation through the disruption of TLR-2 and TLR-4 association

scientific article

Coxiella burnetii stimulates production of RANTES and MCP-1 by mononuclear cells: modulation by adhesion to endothelial cells and its implication in Q fever.

scientific article published on December 2006

Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing

scientific article published on October 2002

Coxiella burnetii, the agent of Q fever, replicates within trophoblasts and induces a unique transcriptional response

scientific article

Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages

scientific article

Cross-protection among Rickettsia species and subspecies in a guinea pig model of cutaneous infection

scientific article published on 9 July 2012

Defective Granuloma Formation in Elderly Infected Patients

scientific article published on 29 April 2020

Defective monocyte dynamics in Q fever granuloma deficiency

scientific article published on 20 February 2012

Deficient transendothelial migration of leukocytes in Q fever: the role played by interleukin-10.

scientific article

Dysregulation of cytokines in acute Q fever: role of interleukin-10 and tumor necrosis factor in chronic evolution of Q fever

scientific article published on 6 March 2003

Early sex-specific modulation of the molecular clock in trauma

scientific article published on January 2014

Ectoparasitism and vector-borne diseases in 930 homeless people from Marseilles

scientific article published on January 2005

Effect of sex on Coxiella burnetii infection: protective role of 17beta-estradiol

scientific article published on 9 January 2004

Effects ofCoxiella burnetiion MAPKinases phosphorylation: Figure 1 ⬇️

scientific article published on August 30, 2011

Epidemic typhus

scientific article

Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia

scientific article

Evaluation of current and new biomarkers in severe preeclampsia: a microarray approach reveals the VSIG4 gene as a potential blood biomarker

scientific article

Exacerbation of circadian rhythms of core body temperature and sepsis in trauma patients

scientific article published on 16 July 2020

For Whom the Clock Ticks: Clinical Chronobiology for Infectious Diseases

scientific article published on 09 July 2020

Foxp3(+)CD4(+)CD25(+) regulatory T cells are increased in patients with Coxiella burnetii endocarditis

scientific article published on 22 December 2011

From Q Fever to Coxiella burnetii Infection: a Paradigm Change

scientific article

Full-Term Human Placental Macrophages Eliminate Coxiella burnetii Through an IFN-γ Autocrine Loop

scientific article published on 29 October 2019

GNS561 exhibits potent in vitro antiviral activity against SARS-CoV-2 through autophagy inhibition

scientific article published on 06 October 2020

Genomic, proteomic, and transcriptomic analysis of virulent and avirulent Rickettsia prowazekii reveals its adaptive mutation capabilities

scientific article

Global analysis of circulating immune cells by matrix-assisted laser desorption ionization time-of-flight mass spectrometry

scientific article

High Concentrations of Serum Soluble E-Cadherin in Patients With Q Fever

scientific article published on 21 June 2019

Hijacked phagosomes and leukocyte activation: an intimate relationship

scientific article published on 18 August 2010

IFN-gamma-induced apoptosis and microbicidal activity in monocytes harboring the intracellular bacterium Coxiella burnetii require membrane TNF and homotypic cell adherence

scientific article published on December 2002

IL-16 is critical for Tropheryma whipplei replication in Whipple's disease

scientific article published on October 2005

IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation ⬇️

scientific article published on October 21, 2010

Imbalance of circulating lymphoid cells in Q fever endocarditis

scientific article published on 4 December 2014

Imbalance of circulating monocyte subsets and PD-1 dysregulation in Q fever endocarditis: the role of IL-10 in PD-1 modulation

scientific article published on 11 September 2014

Immune Modulation as a Therapeutic Option During the SARS-CoV-2 Outbreak: The Case for Antimalarial Aminoquinolines

scientific article published on 28 August 2020

Immune Response and Coxiella burnetii Invasion ⬇️

scientific article published on January 1, 2012

Immunomodulatory Drugs Exert Anti-Leukemia Effects in Acute Myeloid Leukemia by Direct and Immunostimulatory Activities.

scientific article

Impaired Granuloma Formation in Sepsis: Impact of Monocytopenia

scientific article published on 21 July 2016

Impaired Stimulation of p38α-MAPK/Vps41-HOPS by LPS from Pathogenic Coxiella burnetii Prevents Trafficking to Microbicidal Phagolysosomes

scholarly article published by Philippe Soubeyran in 2012

Increased levels of circulating IL-16 and apoptosis markers are related to the activity of Whipple's disease

scientific article

Infection of endothelial cells with virulent Rickettsia prowazekii increases the transmigration of leukocytes

scientific article

Interest of IgG and IgM antiprothrombin autoantibodies in the exploration of antiphospholipid syndrome: a 5-year retrospective study

scientific article published on 19 October 2019

Interleukin-4 induces Coxiella burnetii replication in human monocytes but not in macrophages

scientific article published on June 2003

Intracellular bacteria interfere with dendritic cell functions: role of the type I interferon pathway

scientific article

Intracellular life of Coxiella burnetii in macrophages

scientific article published on May 2009

Intracellular trafficking of Parachlamydia acanthamoebae

scientific article published on April 2005

Is the association between IgG anti-cardiolipin autoantibodies and COVID-19 severity related to the lung injury or to the SARS-CoV-2 infection?

scientific article published on 31 December 2020

Isolation of Human Placental Mast Cells

scientific article published on 25 July 2018

Lack of microbicidal response in human macrophages infected with Parachlamydia acanthamoebae

scientific article published on 21 March 2005

Link between impaired maturation of phagosomes and defective Coxiella burnetii killing in patients with chronic Q fever

scientific article published on 7 October 2004

Lipopolysaccharide from Coxiella burnetii is involved in bacterial phagocytosis, filamentous actin reorganization, and inflammatory responses through Toll-like receptor 4.

scientific article published on March 2004

MALDI-TOF MS monitoring of PBMC activation status in sepsis

scientific article published on 31 July 2018

Macrophage polarization in bacterial infections

scientific article published on September 2008

Mast Cell Cytonemes as a Defense Mechanism against Coxiella burnetii

scientific article published on 16 April 2019

Methanogenic Archaea: Emerging Partners in the Field of Allergic Diseases

scientific article published on 01 December 2019

Monocyte responses in the context of Q fever: from a static polarized model to a kinetic model of activation

scientific article published on 24 June 2013

Murine model of infection by Tropheryma whipplei

scientific article

Myeloid decidual dendritic cells and immunoregulation of pregnancy: defective responsiveness to Coxiella burnetii and Brucella abortus

scientific article

Nanobacteria are mineralo fetuin complexes

scientific article published on 8 February 2008

Natural history of COVID-19 and therapeutic options

scientific article published on 24 December 2020

New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis

scientific article

Orientia tsutsugamushi stimulates an original gene expression program in monocytes: relationship with gene expression in patients with scrub typhus

scientific article

Orientia tsutsugamushi, the causative agent of scrub typhus, induces an inflammatory program in human macrophages

scientific article published on 23 October 2012

Overexpression of the Per2 gene in male patients with acute Q fever

scientific article published on 14 September 2012

Parachlamydia acanthamoebae Enters and Multiplies within Human Macrophages and Induces Their Apoptosis.

scientific article published in January 2004

Parachlamydia acanthamoebae enters and multiplies within human macrophages and induces their apoptosis [corrected].

scientific article

Pathogenic brucellae replicate in human trophoblasts.

scientific article published on 9 January 2013

Persistence of Coxiella burnetii, the agent of Q fever, in murine adipose tissue

scientific article

Persistent Coxiella burnetii infection in mice overexpressing IL-10: an efficient model for chronic Q fever pathogenesis

scientific article

Phenotypic diversity and emerging new tools to study macrophage activation in bacterial infectious diseases

scientific article

Placental macrophages are impaired in chorioamnionitis, an infectious pathology of the placenta

scientific article published on 25 October 2013

Placental macrophages: Origin, heterogeneity, function and role in pregnancy-associated infections

scientific article published on 17 October 2020

Preeclampsia: Impaired inflammatory response mediated by Toll-like receptors

scientific article published on 26 November 2007

Progenitor mast cells and tryptase in Q fever

scientific article published on 20 March 2019

Programmed death ligand-1 expression and memory T-cell generation in Coxiella burnetii infection

scientific article published on 11 February 2015

Reply to "Circadian Rhythm Disruption and Sepsis in Severe Trauma Patients" Shock [epub ahead of print]

scientific article published on 01 December 2019

Rickettsial diseases: from Rickettsia-arthropod relationships to pathophysiology and animal models

scientific article published on April 2008

Role for the CD28 molecule in the control of Coxiella burnetii infection

scientific article

Role of innate and adaptive immunity in the control of Q fever

scientific article published on January 2012

Screening in planarians identifies MORN2 as a key component in LC3-associated phagocytosis and resistance to bacterial infection

scientific article published on September 2014

Sex-related differences in gene expression following Coxiella burnetii infection in mice: potential role of circadian rhythm

scientific article

Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification

scientific article published on March 2002

T-Bet Controls Susceptibility of Mice to Coxiella burnetii Infection

scientific article published on 14 July 2020

TLR2 is necessary to inflammatory response in Coxiella burnetii infection

scientific article

The E-Cadherin Cleavage Associated to Pathogenic Bacteria Infections Can Favor Bacterial Invasion and Transmigration, Dysregulation of the Immune Response and Cancer Induction in Humans

scientific article published on 08 November 2019

The gene expression analysis of blood reveals S100A11 and AQP9 as potential biomarkers of infective endocarditis

scientific article

The ligands of Numb proteins X1 and X2 are specific markers for chronic Q fever

scientific article published on February 2012

The transcriptional programme of human heart valves reveals the natural history of infective endocarditis

scientific article

The two faces of interleukin 10 in human infectious diseases

scientific article published on September 2006

The uptake of apoptotic cells drives Coxiella burnetii replication and macrophage polarization: a model for Q fever endocarditis

scientific article

Thrombosis and antiphospholipid antibody syndrome during acute Q fever: A cross-sectional study

scientific article

Tobacco mosaic virus in the lungs of mice following intra-tracheal inoculation

scientific article

Tropheryma whipplei glycosylation in the pathophysiologic profile of Whipple's disease

scientific article

Tropheryma whipplei, the agent of Whipple's disease, affects the early to late phagosome transition and survives in a Rab5- and Rab7-positive compartment

scientific article (publication date: 2014)

Tumor Necrosis Factor-Alpha Antagonist Interferes With the Formation of Granulomatous Multinucleated Giant Cells: New Insights Into Mycobacterium tuberculosis Infection

scientific article published on 14 August 2019

Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei

scientific article

Vanin-1 controls granuloma formation and macrophage polarization in Coxiella burnetii infection.

scientific article published on January 2007

Whipple disease: intestinal infiltrating cells exhibit a transcriptional pattern of M2/alternatively activated macrophages.

scientific article

Whipple's disease: a macrophage disease

scientific article

Whipple's disease: immunospecific and quantitative immunohistochemical study of intestinal biopsy specimens

scientific article published on June 2003

Whole-cell MALDI-TOF MS: a new tool to assess the multifaceted activation of macrophages

scientific article

Whole-cell MALDI-TOF mass spectrometry is an accurate and rapid method to analyze different modes of macrophage activation

scientific article

Whole-cell MALDI-TOF mass spectrometry: a tool for immune cell analysis and characterization.

scientific article

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