List of works - David L Woodland

A mouse model for infectious mononucleosis

scientific article

A replication-deficient murine gamma-herpesvirus blocked in late viral gene expression can establish latency and elicit protective cellular immunity

scientific article published on 01 December 2007

Activated primary and memory CD8 T cells migrate to nonlymphoid tissues regardless of site of activation or tissue of origin.

scientific article published in April 2004

Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cells

scientific article

Aging and CD8+ T cell immunity to respiratory virus infections

scientific article

Antibody-mediated control of persistent gamma-herpesvirus infection

scientific article published on 01 April 2002

Antigen-specific CD8+ T cell clonal expansions develop from memory T cell pools established by acute respiratory virus infections

scientific article

Antigen-specific memory regulatory CD4+Foxp3+ T cells control memory responses to influenza virus infection

scientific article published on 6 March 2013

Antiviral memory T-cell responses in the lung

scientific article

Aryl hydrocarbon receptor activation impairs the priming but not the recall of influenza virus-specific CD8+ T cells in the lung

scientific article published in November 2006

CXCR3 directs antigen-specific effector CD4+ T cell migration to the lung during parainfluenza virus infection

scientific article published on 04 September 2009

Correction: Early dysregulation of the memory CD8+ T cell repertoire leads to compromised immune responses to secondary viral infection in the aged

scientific article published on 11 October 2013

Cutting Edge: Effector Memory CD8+ T Cells in the Lung Airways Retain the Potential to Mediate Recall Responses ⬇️

scientific article published on October 1, 2003

Cutting edge: Antigen is not required for the activation and maintenance of virus-specific memory CD8+ T cells in the lung airways

scientific article published in April 2007

Cutting edge: T-bet and IL-27R are critical for in vivo IFN-gamma production by CD8 T cells during infection

scientific article published on 01 January 2008

Cutting edge: effector memory CD8+ T cells play a prominent role in recall responses to secondary viral infection in the lung

scientific article published in June 2004

Cutting edge: virus-specific CD4+ memory T cells in nonlymphoid tissues express a highly activated phenotype

scientific article published in December 2002

De novo infection of B cells during murine gammaherpesvirus 68 latency

scientific article published on 17 August 2011

Differential antigen presentation regulates the changing patterns of CD8+ T cell immunodominance in primary and secondary influenza virus infections

scientific article

Differential contributions of central and effector memory T cells to recall responses

scientific article

Differential gamma-herpesvirus distribution in distinct anatomical locations and cell subsets during persistent infection in mice

scientific article published in April 2003

Early dysregulation of the memory CD8+ T cell repertoire leads to compromised immune responses to secondary viral infection in the aged.

scientific article published on 18 December 2012

Early establishment of gamma-herpesvirus latency: implications for immune control

scientific article

Gamma-herpesvirus latency is preferentially maintained in splenic germinal center and memory B cells

scientific article

Gammaherpesvirus latency induces antibody-associated thrombocytopenia in mice

scientific article

IL-15 regulates both quantitative and qualitative features of the memory CD8 T cell pool

scientific article published on 30 November 2009

Identification of protective and non-protective T cell epitopes in influenza

scientific article published on 18 August 2005

Immunity and age: living in the past?

scientific article published on 30 May 2006

Immunity to emerging pathogens

scientific article published on October 2008

Immunity to the conserved influenza nucleoprotein reduces susceptibility to secondary bacterial infections

scientific article

Immunity: it's in our bones.

scientific article published in February 2005

Impact of ageing on the response and repertoire of influenza virus-specific CD4 T cells ⬇️

scientific article

Importance of antibody in virus infection and vaccine-mediated protection by a latency-deficient recombinant murine γ-herpesvirus-68

scientific article published on 23 December 2011

Infection of dendritic cells by a gamma2-herpesvirus induces functional modulation

scientific article

Intraepithelial T-cell cytotoxicity, induced bronchus-associated lymphoid tissue, and proliferation of pneumocytes in experimental mouse models of influenza

scientific article

Long-term maintenance of virus-specific effector memory CD8+ T cells in the lung airways depends on proliferation

scientific article published in November 2002

Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo

scientific article

Lymphotoxin-alpha-deficient mice make delayed, but effective, T and B cell responses to influenza.

scientific article published in November 2002

Maintenance of long term gamma-herpesvirus B cell latency is dependent on CD40-mediated development of memory B cells

scientific article published on July 2003

Maintenance of peripheral T cell responses during Mycobacterium tuberculosis infection

scientific article published on October 2012

Memory T cell populations in the lung airways are maintained by continual recruitment

scientific article

Murid herpesvirus 4 strain 68 M2 protein is a B-cell-associated antigen important for latency but not lymphocytosis

scientific article published on September 2003

Nonmalignant clonal expansions of memory CD8+ T cells that arise with age vary in their capacity to mount recall responses to infection

scientific article

Nonspecific recruitment of memory CD8+ T cells to the lung airways during respiratory virus infections

scientific article published in February 2003

Persistence and turnover of antigen-specific CD4 T cells during chronic tuberculosis infection in the mouse.

scientific article

Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response

scientific article

Perturbation of B cell activation in SLAM-associated protein-deficient mice is associated with changes in gammaherpesvirus latency reservoirs

scientific article published on 01 February 2007

Priming with cold-adapted influenza A does not prevent infection but elicits long-lived protection against supralethal challenge with heterosubtypic virus

scientific article published in January 2007

Production of calcium-mobilizing metabolites by a novel member of the ADP-ribosyl cyclase family expressed in Schistosoma mansoni

scientific article published in August 2005

Promotion of a subdominant CD8 T cell response during murine gammaherpesvirus 68 infection in the absence of CD4 T cell help

scientific article

Reliable generation and use of MHC class II:gamma2aFc multimers for the identification of antigen-specific CD4(+) T cells.

scientific article published in December 2002

Renewal of peripheral CD8+ memory T cells during secondary viral infection of antibody-sufficient mice.

scientific article published in June 2003

Specific niches for lung-resident memory CD8+ T cells at the site of tissue regeneration enable CD69-independent maintenance.

scientific article

T cell reactivity during infectious mononucleosis and persistent gammaherpesvirus infection in mice

scientific article published in March 2004

T cell responses to influenza virus infection: effector and memory cells

scientific article published in January 2004

T-cell immunosenescence: lessons learned from mouse models of aging

scientific article published on 21 June 2009

T-cell memory and recall responses to respiratory virus infections

scientific article published on June 2006

The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections

scientific article published on July 2008

The functional heterogeneity of type 1 effector T cells in response to infection is related to the potential for IFN-gamma production.

scientific article published in June 2005

The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues

scientific article published on July 2002

The omentum is a site of protective IgM production during intracellular bacterial infection

scientific article

The route of priming influences the ability of respiratory virus-specific memory CD8+ T cells to be activated by residual antigen

scientific article

Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge

scientific article published on July 2010

Uneven distribution of MHC class II epitopes within the influenza virus

scientific article

Vaccination with an acidic polymerase epitope of influenza virus elicits a potent antiviral T cell response but delayed clearance of an influenza virus challenge

scientific article published in January 2005

Vaccines against pandemic influenza.

scientific article

Viral immunology: challenges associated with the progression from bench to clinic

scientific article published on 01 December 2002

γ-Herpesvirus reactivation differentially stimulates epitope-specific CD8 T cell responses

scientific article published on 9 March 2012

List of works by David L Woodland

A mouse model for infectious mononucleosis

A replication-deficient murine gamma-herpesvirus blocked in late viral gene expression can establish latency and elicit protective cellular immunity

Activated primary and memory CD8 T cells migrate to nonlymphoid tissues regardless of site of activation or tissue of origin.

Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cells

Aging and CD8+ T cell immunity to respiratory virus infections

Antibody-mediated control of persistent gamma-herpesvirus infection

Antigen-specific CD8+ T cell clonal expansions develop from memory T cell pools established by acute respiratory virus infections

Antigen-specific memory regulatory CD4+Foxp3+ T cells control memory responses to influenza virus infection

Antiviral memory T-cell responses in the lung

Aryl hydrocarbon receptor activation impairs the priming but not the recall of influenza virus-specific CD8+ T cells in the lung

CXCR3 directs antigen-specific effector CD4+ T cell migration to the lung during parainfluenza virus infection

Correction: Early dysregulation of the memory CD8+ T cell repertoire leads to compromised immune responses to secondary viral infection in the aged

Cutting Edge: Effector Memory CD8+ T Cells in the Lung Airways Retain the Potential to Mediate Recall Responses ⬇️

Cutting edge: Antigen is not required for the activation and maintenance of virus-specific memory CD8+ T cells in the lung airways

Cutting edge: T-bet and IL-27R are critical for in vivo IFN-gamma production by CD8 T cells during infection

Cutting edge: effector memory CD8+ T cells play a prominent role in recall responses to secondary viral infection in the lung

Cutting edge: virus-specific CD4+ memory T cells in nonlymphoid tissues express a highly activated phenotype

De novo infection of B cells during murine gammaherpesvirus 68 latency

Differential antigen presentation regulates the changing patterns of CD8+ T cell immunodominance in primary and secondary influenza virus infections

Differential contributions of central and effector memory T cells to recall responses

Differential gamma-herpesvirus distribution in distinct anatomical locations and cell subsets during persistent infection in mice

Early dysregulation of the memory CD8+ T cell repertoire leads to compromised immune responses to secondary viral infection in the aged.

Early establishment of gamma-herpesvirus latency: implications for immune control

Gamma-herpesvirus latency is preferentially maintained in splenic germinal center and memory B cells

Gammaherpesvirus latency induces antibody-associated thrombocytopenia in mice

IL-15 regulates both quantitative and qualitative features of the memory CD8 T cell pool

Identification of protective and non-protective T cell epitopes in influenza

Immunity and age: living in the past?

Immunity to emerging pathogens

Immunity to the conserved influenza nucleoprotein reduces susceptibility to secondary bacterial infections

Immunity: it's in our bones.

Impact of ageing on the response and repertoire of influenza virus-specific CD4 T cells ⬇️

Importance of antibody in virus infection and vaccine-mediated protection by a latency-deficient recombinant murine γ-herpesvirus-68

Infection of dendritic cells by a gamma2-herpesvirus induces functional modulation

Intraepithelial T-cell cytotoxicity, induced bronchus-associated lymphoid tissue, and proliferation of pneumocytes in experimental mouse models of influenza

Long-term maintenance of virus-specific effector memory CD8+ T cells in the lung airways depends on proliferation

Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo

Lymphotoxin-alpha-deficient mice make delayed, but effective, T and B cell responses to influenza.

Maintenance of long term gamma-herpesvirus B cell latency is dependent on CD40-mediated development of memory B cells

Maintenance of peripheral T cell responses during Mycobacterium tuberculosis infection

Memory T cell populations in the lung airways are maintained by continual recruitment

Murid herpesvirus 4 strain 68 M2 protein is a B-cell-associated antigen important for latency but not lymphocytosis

Nonmalignant clonal expansions of memory CD8+ T cells that arise with age vary in their capacity to mount recall responses to infection

Nonspecific recruitment of memory CD8+ T cells to the lung airways during respiratory virus infections

Persistence and turnover of antigen-specific CD4 T cells during chronic tuberculosis infection in the mouse.

Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response

Perturbation of B cell activation in SLAM-associated protein-deficient mice is associated with changes in gammaherpesvirus latency reservoirs

Priming with cold-adapted influenza A does not prevent infection but elicits long-lived protection against supralethal challenge with heterosubtypic virus

Production of calcium-mobilizing metabolites by a novel member of the ADP-ribosyl cyclase family expressed in Schistosoma mansoni

Promotion of a subdominant CD8 T cell response during murine gammaherpesvirus 68 infection in the absence of CD4 T cell help

Reliable generation and use of MHC class II:gamma2aFc multimers for the identification of antigen-specific CD4(+) T cells.

Renewal of peripheral CD8+ memory T cells during secondary viral infection of antibody-sufficient mice.

Specific niches for lung-resident memory CD8+ T cells at the site of tissue regeneration enable CD69-independent maintenance.

T cell reactivity during infectious mononucleosis and persistent gammaherpesvirus infection in mice

T cell responses to influenza virus infection: effector and memory cells

T-cell immunosenescence: lessons learned from mouse models of aging

T-cell memory and recall responses to respiratory virus infections

The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections

The functional heterogeneity of type 1 effector T cells in response to infection is related to the potential for IFN-gamma production.

The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues

The omentum is a site of protective IgM production during intracellular bacterial infection

The route of priming influences the ability of respiratory virus-specific memory CD8+ T cells to be activated by residual antigen

Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge

Uneven distribution of MHC class II epitopes within the influenza virus

Vaccination with an acidic polymerase epitope of influenza virus elicits a potent antiviral T cell response but delayed clearance of an influenza virus challenge

Vaccines against pandemic influenza.

Viral immunology: challenges associated with the progression from bench to clinic

γ-Herpesvirus reactivation differentially stimulates epitope-specific CD8 T cell responses