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List of works by Julian R Molina

53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice

scientific article

88P: Use of brain imaging in the management of patients with lymph node negative multifocal lung cancer

scientific article published on 15 April 2016

A First-in-Human Phase I Study of the Oral p38 MAPK Inhibitor, Ralimetinib (LY2228820 Dimesylate), in Patients with Advanced Cancer

scientific article published on 18 November 2015

A Phase II NCCTG study of irinotecan and docetaxel in previously treated patients with non-small cell lung cancer

scientific article published on 01 June 2006

A Phase II Study of Pazopanib in Patients with Malignant Pleural Mesothelioma: NCCTG N0623 (Alliance)

scientific article published on 24 December 2019

A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Canc

scientific article published on 09 October 2019

A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes.

scientific article published on April 2003

A front-line window of opportunity phase 2 study of sorafenib in patients with advanced nonsmall cell lung cancer: North Central Cancer Treatment Group Study N0326.

scientific article published on December 2010

A genetic cell context-dependent role for ZEB1 in lung cancer.

scientific article published on 26 July 2016

A multicenter phase 2 trial of pazopanib in metastatic and progressive medullary thyroid carcinoma: MC057H.

scientific article

A multiinstitutional phase 2 trial of pazopanib monotherapy in advanced anaplastic thyroid cancer

scientific article

A phase I and pharmacokinetic study of the selective, non-peptidic inhibitor of matrix metalloproteinase BAY 12-9566 in combination with etoposide and carboplatin

scientific article

A phase I study of cilengitide and paclitaxel in patients with advanced solid tumors

scientific article

A phase I study of the VEGFR kinase inhibitor vatalanib in combination with the mTOR inhibitor, everolimus, in patients with advanced solid tumors

scientific article published on 24 April 2020

A phase I study of the farnesyltransferase inhibitor Tipifarnib in combination with the epidermal growth factor tyrosine kinase inhibitor Erlotinib in patients with advanced solid tumors

scientific article published on 31 August 2018

A phase I study of the vascular endothelial growth factor inhibitor Vatalanib in combination with Pemetrexed disodium in patients with advanced solid tumors

scientific article published on 31 October 2018

A phase I/II study of bortezomib in combination with paclitaxel, carboplatin, and concurrent thoracic radiation therapy for non-small-cell lung cancer: North Central Cancer Treatment Group (NCCTG)-N0321

scientific article

A phase II trial of the Src-kinase inhibitor saracatinib after four cycles of chemotherapy for patients with extensive stage small cell lung cancer: NCCTG trial N-0621.

scientific article

A randomized phase II study of gemcitabine and carboplatin with or without cediranib as first-line therapy in advanced non-small-cell lung cancer: North Central Cancer Treatment Group Study N0528

scientific article

A role for candidate tumor-suppressor gene TCEAL7 in the regulation of c-Myc activity, cyclin D1 levels and cellular transformation

scientific article

A safety, tolerability, and pharmacokinetic analysis of two phase I studies of multitargeted small molecule tyrosine kinase inhibitor XL647 with an intermittent and continuous dosing schedule in patients with advanced solid malignancies

scientific article published on 20 July 2018

Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagus

scientific article published in September 2005

Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia

scientific article published on February 2006

Adjuvant chemoradiation therapy with high-dose versus weekly cisplatin for resected, locally-advanced HPV/p16-positive and negative head and neck squamous cell carcinoma

scientific article published on 24 January 2014

Advances in chemotherapy of non-small cell lung cancer

scientific article published on October 2006

An International Phase 2 Study of Pazopanib in Progressive and Metastatic Thyroglobulin Antibody Negative Radioactive Iodine Refractory Differentiated Thyroid Cancer

scientific article published on 14 June 2020

Association of Sex, Age, and Eastern Cooperative Oncology Group Performance Status With Survival Benefit of Cancer Immunotherapy in Randomized Clinical Trials: A Systematic Review and Meta-analysis

scientific article published on 03 August 2020

BAP1 loss is unusual in well-differentiated papillary mesothelioma and may predict development of malignant mesothelioma

scientific article published on 12 May 2018

Bone marrow angiogenesis in multiple myeloma: closing in on the loop

scientific article published on 01 February 2003

Brief report: a phase II "window-of-opportunity" frontline study of the MTOR inhibitor, temsirolimus given as a single agent in patients with advanced NSCLC, an NCCTG study.

scientific article published in May 2012

CRM1 inhibitor anti-tumor activity is enhanced with salicylates by S-phase arrest and impaired DNA-damage repair

scientific article published on 02 November 2020

Can gene expression profiling predict survival for patients with squamous cell carcinoma of the lung?

scientific article

Carcinoid Heart Disease in Patients With Bronchopulmonary Carcinoid

scientific article published on 07 July 2018

Cardiovascular Health and Outcomes in Cancer Patients Receiving Immune Checkpoint Inhibitors

scientific article published on 05 March 2020

Characterization of Comorbidities Limiting the Recruitment of Patients in Early Phase Clinical Trials

scientific article published on 09 November 2018

Chemotherapy for Non-Small-Cell Lung Carcinoma: From a Blanket Approach to Individual Therapy ⬇️

scientific article published on April 15, 2011

Chemotherapy-induced ovarian failure: manifestations and management

scientific article

Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA

scientific article

Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization

scientific article published on 31 May 2016

Concurrent MCL1 and JUN amplification in pseudomyxoma peritonei: a comprehensive genetic profiling and survival analysis.

scientific article published on 26 December 2013

Correlation between polymorphisms of the reduced folate carrier gene (SLC19A1) and survival after pemetrexed-based therapy in non-small cell lung cancer: a North Central Cancer Treatment Group-based exploratory study.

scientific article published on September 2010

Development of a multidisciplinary, multicampus subspecialty practice in endocrine cancers

scientific article published on 01 May 2012

Development of a multidisciplinary, multicampus subspecialty practice in endocrine cancers.

scientific article

Distribution of Mediastinal Lesions Across Multi-Institutional, International, Radiology Databases

scientific article published on 20 December 2019

Do patients with schizophrenia receive state-of-the-art lung cancer therapy? A brief report

scientific article published on July 2008

Dopamine D2 receptor agonists inhibit lung cancer progression by reducing angiogenesis and tumor infiltrating myeloid derived suppressor cells

scientific article

Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis

scientific article

Editorial: pleural recurrence of thymoma-what is the value of intra-thoracic chemo-hyperthermia?

scientific article published in October 2017

Effect of disrupting seven-in-absentia homolog 2 function on lung cancer cell growth

scientific article

Efficacy of Second-Line Chemotherapy in Extrapulmonary Neuroendocrine Carcinoma

scientific article published on 01 April 2020

Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study.

scientific article

Elevated Cellular PD1/PD-L1 Expression Confers Acquired Resistance to Cisplatin in Small Cell Lung Cancer Cells

scientific article

Enhanced Survival in Locoregionally Confined Anaplastic Thyroid Carcinoma: A Single-Institution Experience Using Aggressive Multimodal Therapy ⬇️

scientific article published on December 16, 2010

Epigenetic silencing of HSulf-1 in ovarian cancer:implications in chemoresistance.

scientific article published on 19 February 2007

Evaluation of lapatinib and topotecan combination therapy: tissue culture, murine xenograft, and phase I clinical trial data

scientific article

FAVL elevation in human tumors disrupts Fanconi anemia pathway signaling and promotes genomic instability and tumor growth

scientific article published on 19 April 2010

First-in-Human Study of PF-05212384 (PKI-587), a Small-Molecule, Intravenous, Dual Inhibitor of PI3K and mTOR in Patients with Advanced Cancer.

scientific article published on 4 February 2015

Frequent methylation of eyes absent 4 gene in Barrett's esophagus and esophageal adenocarcinoma

scientific article published in April 2005

Gender differences in non-small-cell lung cancer survival: an analysis of 4,618 patients diagnosed between 1997 and 2002

scientific article published on 01 July 2004

Genetic Variations in Multiple Drug Action Pathways and Survival in Advanced Stage Non–Small Cell Lung Cancer Treated with Chemotherapy ⬇️

scientific article published on June 1, 2011

Identification and Development of a Lung Adenocarcinoma PDX Model With STRN-ALK Fusion

scientific article published on 20 November 2018

Implementation of artificial intelligence (AI) for lung cancer clinical trial matching in a tertiary cancer center

scientific article published on 01 April 2019

Lung Cancer: Evolving Concepts ⬇️

scientific article published on 01 February 2011

Management of Multifocal Lung Cancer: Results of a Survey

scientific article published on 2 June 2017

Matrix detachment and proteasomal inhibitors diminish Sulf-2 expression in breast cancer cell lines and mouse xenografts

scientific article published on 15 February 2013

Methylation induced gene silencing of HtrA3 in smoking-related lung cancer

scientific article

NCCTG N0821 (Alliance): a phase II first-line study of pemetrexed, carboplatin, and bevacizumab in elderly patients with advanced nonsquamous non-small-cell lung cancer with good performance status

scientific article

NUT midline carcinoma: an aggressive intrathoracic neoplasm

scientific article published in October 2013

Nomogram prediction of overall survival for patients with non-small-cell lung cancer incorporating pretreatment peripheral blood markers.

scientific article published on 27 December 2017

Nomograms Predict Overall Survival for Patients with Small-Cell Lung Cancer Incorporating Pretreatment Peripheral Blood Markers

scientific article published on August 2015

Non-Small Cell Lung Cancer: Epidemiology, Screening, Diagnosis, and Treatment

scientific article published on 01 August 2019

Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship

scientific article

Oncogenic Pathways, Molecularly Targeted Therapies, and Highlighted Clinical Trials in Non–Small-Cell Lung Cancer (NSCLC) ⬇️

scientific article published on 08 December 2011

Oncolytic Measles Virotherapy and Opposition to Measles Vaccination

scientific article published on 22 June 2019

Oropharyngeal cancer biology and treatment: insights from messenger RNA sequence analysis and transoral robotic surgery.

scientific article published on November 2012

P2.41 (also presented as PD1.06): Pembrolizumab vs Docetaxel for Previously Treated NSCLC (KEYNOTE-010): Archival vs New Tumor Samples for PD-L1 Assessment: Track: Immunotherapy

scientific article published on 22 September 2016

PD1.06 (also presented as P2.41): Pembrolizumab vs Docetaxel for Previously Treated NSCLC (KEYNOTE-010): Archival vs New Tumor Samples for PD-L1 Assessment

scientific article published on 22 September 2016

PFKFB3 inhibition reprograms malignant pleural mesothelioma to nutrient stress-induced macropinocytosis and ER stress as independent binary adaptive responses

scientific article published on 27 September 2019

Pathways impacted by genomic alterations in pulmonary carcinoid tumors

scientific article published on 19 January 2018

Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial

scientific article

Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of TH-302, a Hypoxia-Activated Prodrug, in Patients with Advanced Solid Malignancies ⬇️

scientific article published on March 17, 2011

Phase 1 study of sorafenib in combination with bortezomib in patients with advanced malignancies.

scientific article published on 26 July 2013

Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer

scientific article published on 21 November 2019

Phase 2 trial of pemetrexed disodium and carboplatin in previously untreated extensive-stage small cell lung cancer, N0423.

scientific article

Phase I dose escalation study of the PKCι inhibitor aurothiomalate for advanced non-small-cell lung cancer, ovarian cancer, and pancreatic cancer.

scientific article

Phase I dose escalation study of the anti insulin-like growth factor-I receptor monoclonal antibody CP-751,871 in patients with refractory solid tumors

scientific article published in October 2007

Phase I pharmacokinetic and pharmacodynamic study of the oral, small-molecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers

scientific article

Phase I trial of sorafenib in combination with gefitinib in patients with refractory or recurrent non-small cell lung cancer

scientific article published on 01 May 2007

Phase I/II Study of AT-101 with Topotecan in Relapsed and Refractory Small Cell Lung Cancer ⬇️

scientific article published on October 1, 2010

Phase II NCCTG trial of oral topotecan and paclitaxel with G-CSF (filgrastim) support in patients with previously untreated extensive-stage small cell lung cancer

scientific article

Phase II trial of pemetrexed plus bevacizumab for second-line therapy of patients with advanced non-small-cell lung cancer: NCCTG and SWOG study N0426.

scientific article

Phase III Randomized, Placebo-Controlled, Double-Blind Trial of Celecoxib in Addition to Standard Chemotherapy for Advanced Non-Small-Cell Lung Cancer With Cyclooxygenase-2 Overexpression: CALGB 30801 (Alliance).

scientific article published on 10 May 2017

Pralatrexate, a dihydrofolate reductase inhibitor for the potential treatment of several malignancies.

scientific article published on July 2008

Predictors of survival from urachal cancer: a Mayo Clinic study of 49 cases

scientific article published on December 2007

Primary adenoid cystic carcinoma of the lung: absence of KIT mutations

scientific article published on 01 December 2007

Primary salivary gland-type lung cancer: spectrum of clinical presentation, histopathologic and prognostic factors

scientific article published on November 2007

Prophylactic cranial irradiation in small-cell lung cancer: Findings from a North Central Cancer Treatment Group Pooled Analysis ⬇️

scientific article published on July 10, 2012

Pulmonary Artery Agenesis Associated With Emphysema and Multiple Invasive Non-Small Cell Lung Cancers

scientific article published on June 2015

Pulmonary Neuroendocrine Tumors: Adjuvant and Systemic Treatments

scientific article published on 29 August 2020

RESPONSE OF UVEAL METASTASES TO ALK INHIBITORS IN ALK-POSITIVE NON-SMALL-CELL LUNG CANCER.

scientific article

Ramifications of severe organ dysfunction in newly diagnosed patients with small cell lung cancer: contemporary experience from a single institution

scientific article

Ranibizumab combined with low-dose sorafenib for exudative age-related macular degeneration

scientific article published on February 2008

Salivary gland-type lung carcinomas: an EGFR immunohistochemical, molecular genetic, and mutational analysis study.

scientific article published on 27 June 2008

Sarcomatoid Carcinoma of the Lung: The Mayo Clinic Experience in 127 Patients

scientific article published on 21 December 2017

Smoking, Sex, and Non-Small Cell Lung Cancer: Steroid Hormone Receptors in Tumor Tissue (S0424).

scientific article published on 13 January 2018

Study design considerations in clinical outcome research of lung cancer using microarray analysis

scientific article published in November 2004

Surgery for Mesothelioma After Radiation Therapy (SMART); A Single Institution Experience

scientific article published on 24 March 2020

Survival in Response to Multimodal Therapy in Anaplastic Thyroid Cancer

scientific article

Systematic Evaluation of Genetic Variants in Three Biological Pathways on Patient Survival in Low-Stage Non-small Cell Lung Cancer ⬇️

scientific article published on September 1, 2011

The DNA Methyltransferase DNMT1 and Tyrosine-Protein Kinase KIT Cooperatively Promote Resistance to 5-Aza-2'-deoxycytidine (Decitabine) and Midostaurin (PKC412) in Lung Cancer Cells

scientific article

The Ras/Raf/MAPK pathway

scientific article published on January 2006

The Role of Pemetrexed (Alimta®, LY231514) in Lung Cancer Therapy ⬇️

scientific article published on July 1, 2003

The case of a good satellite: outcomes of resected ipsilateral same-lobe satellite pulmonary nodules

scientific article

Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials: A Systematic Review and Meta-analysis

scientific article published on 01 July 2019

Tumor response and progression-free survival as potential surrogate endpoints for overall survival in extensive stage small-cell lung cancer: findings on the basis of North Central Cancer Treatment Group trials

scientific article

Use of archival versus newly collected tumor samples for assessing PD-L1 expression and overall survival: an updated analysis of KEYNOTE-010 trial

scientific article published on 01 February 2019

Worse disease-free survival in never-smokers with ALK+ lung adenocarcinoma.

scientific article published on January 2012

c-Met expression and MET amplification in malignant pleural mesothelioma

scientific article published on 30 April 2016

digit-a tool for detection and identification of genomic interchromosomal translocations

scientific article

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