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List of works by Charles Erlichman

5-Fluorouracil (FUra) and folinic acid (FA) therapy in patients with colorectal cancer

scientific article

5-Fluorouracil and folinic acid in the treatment of metastatic colorectal cancer

scientific article published on 01 September 1987

A First-in-Human Phase I Study of the Oral p38 MAPK Inhibitor, Ralimetinib (LY2228820 Dimesylate), in Patients with Advanced Cancer

scientific article published on 18 November 2015

A Phase 2 Trial of Flavopiridol (Alvocidib) and Cisplatin in Platin-Resistant Ovarian and Primary Peritoneal Carcinoma: MC0261 ⬇️

scientific article published on June 1, 2012

A Phase I Clinical Trial of the Poly(ADP-ribose) Polymerase Inhibitor Veliparib and Weekly Topotecan in Patients with Solid Tumors

scientific article published on 14 November 2017

A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor-Positive Metastatic Breast Cancer

scientific article

A Phase I study of bizelesin (NSC 615291) in patients with advanced solid tumors.

scientific article published in March 2002

A Phase I trial of the farnesyl protein transferase inhibitor R115777 in combination with gemcitabine and cisplatin in patients with advanced cancer

scientific article

A Phase I trial of the farnesyl transferase inhibitor SCH66336: evidence for biological and clinical activity.

scientific article

A Phase II Trial of Neoadjuvant MK-2206, an AKT Inhibitor, with Anastrozole in Clinical Stage II or III PIK3CA-Mutant ER-Positive and HER2-Negative Breast Cancer.

scientific article published on 5 September 2017

A bioassay to measure cytotoxicity of plasma from patients treated with mitomycin C

scientific article published on 01 November 1985

A clinical and pharmacological study of 5-fluorouracil, leucovorin and interferon alfa in advanced colorectal cancer

scientific article published on 01 January 1995

A hierarchical Bayesian design for randomized Phase II clinical trials with multiple groups

scientific article published on 27 April 2017

A limited sample model to predict area under the drug concentration curve for 17-(allylamino)-17-demethoxygeldanamycin and its active metabolite 17-(amino)-17-demethoxygeldanomycin

scientific article published on 20 March 2007

A measles virus vaccine strain derivative as a novel oncolytic agent against breast cancer

scientific article published on 27 April 2006

A multicenter phase 2 trial of pazopanib in metastatic and progressive medullary thyroid carcinoma: MC057H.

scientific article

A multiinstitutional phase 2 trial of pazopanib monotherapy in advanced anaplastic thyroid cancer

scientific article

A phase 2 consortium (P2C) trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) for advanced adenocarcinoma of the pancreas

scientific article

A phase 2 study of temsirolimus (CCI-779) in patients with soft tissue sarcomas: a study of the Mayo phase 2 consortium (P2C).

scientific article published in February 2011

A phase I and pharmacokinetic study of a powder-filled capsule formulation of oral irinotecan (CPT-11) given daily for 5 days every 3 weeks in patients with advanced solid tumors

scientific article published on 19 November 2005

A phase I and pharmacokinetic study of temsirolimus (CCI-779) administered intravenously daily for 5 days every 2 weeks to patients with advanced cancer

scientific article

A phase I and pharmacokinetic study of the selective, non-peptidic inhibitor of matrix metalloproteinase BAY 12-9566 in combination with etoposide and carboplatin

scientific article

A phase I and pharmacologic study of pyrazoloacridine (NSC 366140) and carboplatin in patients with advanced cancer

scientific article published in August 2002

A phase I and pharmacologic study of sequences of the proteasome inhibitor, bortezomib (PS-341, Velcade), in combination with paclitaxel and carboplatin in patients with advanced malignancies

scientific article

A phase I and pharmacologic trial of two schedules of the proteasome inhibitor, PS-341 (bortezomib, velcade), in patients with advanced cancer

scientific article

A phase I clinical and pharmacokinetic study of CS-682 administered orally in advanced malignant solid tumors

scientific article

A phase I study of 153Sm-EDTMP with fixed high-dose melphalan as a peripheral blood stem cell conditioning regimen in patients with multiple myeloma

scientific article published in January 2005

A phase I study of EKB-569 in combination with capecitabine in patients with advanced colorectal cancer

scientific article

A phase I study of cilengitide and paclitaxel in patients with advanced solid tumors

scientific article

A phase I study of combined radiation therapy with 5-fluorouracil and low dose folinic acid in patients with locally advanced pancreatic or biliary carcinoma

scientific article published on 01 January 1996

A phase I study of sequential irinotecan and 5-fluorouracil/leucovorin

scientific article published in October 2002

A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer.

scientific article

A phase I trial of MTA and gemcitabine in patients with locally advanced or metastatic cancer

scientific article published on April 1999

A phase I trial of the IGF-1R antibody Cixutumumab in combination with temsirolimus in patients with metastatic breast cancer ⬇️

scientific article published on April 19, 2013

A phase I trial of the novel farnesyl protein transferase inhibitor, BMS-214662, in combination with paclitaxel and carboplatin in patients with advanced cancer.

scientific article

A phase I trial of twice-weekly 17-allylamino-demethoxy-geldanamycin in patients with advanced cancer

scientific article published on 01 October 2006

A phase IB study of the pharmacokinetics of gemcitabine and pemetrexed, when administered in rapid sequence to patients with advanced solid tumors

scientific article

A phase II safety and efficacy study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor pazopanib in patients with metastatic urothelial cancer

scientific article

A phase II study of 5-fluorouracil, leucovorin and interferon-alpha in advanced pancreatic cancer

scientific article published on 01 October 1993

A phase II study of AT-101 (Gossypol) in chemotherapy-sensitive recurrent extensive-stage small cell lung cancer.

scientific article

A phase II study of AZD2171 (cediranib) in the treatment of patients with acute myeloid leukemia or high-risk myelodysplastic syndrome

scientific article

A phase II study of bortezomib in the treatment of metastatic malignant melanoma

scientific article

A phase II study of gemcitabine in combination with tanespimycin in advanced epithelial ovarian and primary peritoneal carcinoma

scientific article published on November 2011

A phase II study of the orally administered negative enantiomer of gossypol (AT-101), a BH3 mimetic, in patients with advanced adrenal cortical carcinoma

scientific article published on 06 June 2019

A phase II trial of 17-allylamino-17- demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

scientific article

A phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

scientific article

A phase II trial of 5-fluorouracil and 1-leucovorin in patients with metastatic colorectal cancer

scientific article published on 01 February 1996

A phase II trial of bevacizumab plus temsirolimus in patients with advanced hepatocellular carcinoma

scientific article

A phase II trial of tipifarnib in myelofibrosis: primary, post-polycythemia vera and post-essential thrombocythemia

article by R A Mesa et al published 21 June 2007 in Leukemia

A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma

scientific article published on 01 March 1988

A randomized trial of two dose levels of cyclophosphamide, methotrexate, and fluorouracil chemotherapy for patients with metastatic breast cancer

scientific article published in September 1988

A study of paclitaxel, carboplatin, and bortezomib in the treatment of metastatic malignant melanoma: a phase 2 consortium study

scientific article

Abstract 1301: Investigation of a potential pharmacokinetic interaction between ABT-888 and topotecan in a phase I trial

Adjuvant therapy of colon cancer: a review

scientific article

Akt inhibitor MK-2206 in combination with bendamustine and rituximab in relapsed or refractory chronic lymphocytic leukemia: Results from the N1087 alliance study.

scientific article

Akt inhibitor MK2206 selectively targets CLL B-cell receptor induced cytokines, mobilizes lymphocytes and synergizes with bendamustine to induce CLL apoptosis

scientific article

Allopurinol mouthwash for prevention of fluorouracil-induced stomatitis

scientific article published on 01 September 1989

An Evaluation of Postoperative Follow-Up Tests in Colon Cancer Patients Treated for Cure ⬇️

scientific article published on 01 July 1997

An International Phase 2 Study of Pazopanib in Progressive and Metastatic Thyroglobulin Antibody Negative Radioactive Iodine Refractory Differentiated Thyroid Cancer

scientific article published on 14 June 2020

An international, multicenter phase II trial of bortezomib in patients with hepatocellular carcinoma.

scientific article

An open-label, phase I/II study of 5-fluorouracil plus leucovorin in the treatment of rheumatoid arthritis

scientific article published in May 2002

An overview of the clinical pharmacology of N-phosphonacetyl-L-aspartate (PALA), a new antimetabolite.

scientific article published in January 1980

Analysis of phosphoramide mustard by reversed-phase ion pair high pressure liquid chromatography

scientific article published on 01 June 1987

Antineoplastic drug cytotoxicity in a human bladder cancer cell line: implications for intravesical chemotherapy

scientific article published in January 1987

Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742)

scientific article published on 27 March 2018

Antitumor activity of N-phosphonacetyl-L-aspartic acid in combination with nitrobenzylthioinosine

scientific article published on October 1984

Application of a simple competitive protein-binding assay technique to the pharmacokinetics of N-(phosphonacetyl)-L-aspartate in humans

scientific article published on 01 June 1980

Association of DNA methylation and epigenetic inactivation of RASSF1A and beta-catenin with metastasis in small bowel carcinoid tumors

scientific article published on December 2006

Biochemical effects of folate-based inhibitors of thymidylate synthase in MGH-U1 cells

scientific article published on 01 January 1994

Biochemical modulation of 5-fluorouracil with or without leucovorin by a low dose of brequinar in MGH-U1 cells

scientific article published on 01 January 1992

Biochemical modulation of iododeoxyuridine by N6-[4-(morpholinosulfonyl)benzyl]-N6-methyl-2, 6-diaminobenz[cd]indole glucuronate (AG-331) leading to enhanced cytotoxicity

scientific article published in June 1995

Biomarker-driven trial in metastatic pancreas cancer: feasibility in a multicenter study of saracatinib, an oral Src inhibitor, in previously treated pancreatic cancer

scientific article published on 16 August 2012

Cisplatin abrogates the geldanamycin-induced heat shock response

scientific article published on October 2008

Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: a phase 2 consortium/stand up 2 cancer study

scientific article

Combination studies with 3'-azido-3'-deoxythymidine (AZT) plus ICI D1694. Cytotoxic and biochemical effects

scientific article published on December 1993

Combined radical radiation therapy and chemotherapy for primary squamous cell carcinoma of the anal canal.

scientific article

Comparative cytotoxicity of folate-based inhibitors of thymidylate synthase and 5-fluorouracil +/- leucovorin in MGH-U1 cells

scientific article published on 01 January 1994

Comparative pharmacokinetic study of continuous venous infusion fluorouracil and oral fluorouracil with eniluracil in patients with advanced solid tumors

scientific article published in March 2002

Comparison of potential markers of farnesyltransferase inhibition

scientific article published on 01 June 2000

Competitive protein binding assay of methotrexate

scientific article published on 01 January 1982

Context-dependent antagonism between Akt inhibitors and topoisomerase poisons

scientific article published on 25 February 2014

Cytotoxic and biochemical implications of combining AZT and AG-331

scientific article published on 01 January 1995

Cytotoxicity of adriamycin in MGH-U1 cells grown as monolayer cultures, spheroids, and xenografts in immune-deprived mice

scientific article

Cytotoxicity of cisplatin and cisdiammine-1,1-cyclobutane dicarboxylate in MGH-U1 cells grown as monolayers, spheroids, and xenografts.

scientific article published in September 1985

Denileukin diftitox in combination with rituximab for previously untreated follicular B-cell non-Hodgkin's lymphoma ⬇️

scientific article published on October 21, 2011

Development of a multidisciplinary, multicampus subspecialty practice in endocrine cancers

scientific article published on 01 May 2012

Development of a multidisciplinary, multicampus subspecialty practice in endocrine cancers.

scientific article

Development of rational drug combinations with investigational targeted agents

scientific article published on January 2010

Differences between accumulation of 99mTc-MIBI and 201Tl-thallous chloride in tumour cells: role of P-glycoprotein

scientific article published on 01 June 1995

Dinaciclib, a novel CDK inhibitor, demonstrates encouraging single-agent activity in patients with relapsed multiple myeloma.

scientific article

Disposition of cyclophosphamide on two consecutive cycles of treatment in patients with ovarian carcinoma

scientific article published in June 1988

Disposition of total and free cisplatin on two consecutive treatment cycles in patients with ovarian cancer

scientific article published on 01 January 1987

Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells

scientific article

Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924

scientific article

Early results of a phase I trial of oblimersen sodium for relapsed or refractory Waldenstrom's macroglobulinemia

scientific article

Ectopic production of human chorionic gonadotropin: A case report ⬇️

scientific article published on January 1, 1979

Effect of adding the topoisomerase I poison 7-ethyl-10-hydroxycamptothecin (SN-38) to 5-fluorouracil and folinic acid in HCT-8 cells: elevated dTTP pools and enhanced cytotoxicity

scientific article published on 01 January 1998

Effects of 5-fluorouracil and leucovorin in spheroids: a model for solid tumours

scientific article published on March 1991

Effects of thymidylate synthase inhibition on thymidine kinase activity and nucleoside transporter expression

scientific article published on April 1995

Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study.

scientific article

Epidermal growth factor receptor and activated epidermal growth factor receptor expression in gastrointestinal carcinoids and pancreatic endocrine carcinomas

scientific article

Epigenetic therapy using belinostat for patients with unresectable hepatocellular carcinoma: a multicenter phase I/II study with biomarker and pharmacokinetic analysis of tumors from patients in the Mayo Phase II Consortium and the Cancer Therapeuti

scientific article

Evaluation of continuous infusion suramin in metastatic breast cancer: impact on plasma levels of insulin-like growth factors (IGFs) and IGF-binding proteins

scientific article published on 01 October 1997

Evaluation of epothilone B analog in advanced soft tissue sarcoma: a phase II study of the phase II consortium

scientific article

Evaluation of lapatinib and topotecan combination therapy: tissue culture, murine xenograft, and phase I clinical trial data

scientific article

Experience with 5FU + L-leucovorin

scientific article published on 01 January 1993

Expression of insulin receptor isoform A and insulin-like growth factor-1 receptor in human acute myelogenous leukemia: effect of the dual-receptor inhibitor BMS-536924 in vitro

scientific article published on 29 September 2009

Failure of 5-day vinblastine infusion in the treatment of patients with advanced refractory breast cancer

scientific article published on 01 September 1982

Failure of methylprednisolone acetate to prolong the antinauseant effect of intravenous methylprednisolone sodium succinate in patients receiving chemotherapy

scientific article published on 01 October 1988

First-in-Human Phase I Study of the Tamoxifen Metabolite Z-Endoxifen in Women With Endocrine-Refractory Metastatic Breast Cancer

scientific article published on 30 August 2017

Flavopiridol in patients with relapsed or refractory multiple myeloma: a phase 2 trial with clinical and pharmacodynamic end-points.

scientific article published on 17 February 2006

Fluorouracil and leucovorin for metastatic colorectal cancer

scientific article

Fluorouracil/leucovorin study update

scientific article

Gemcitabine and ISIS-2503 for patients with locally advanced or metastatic pancreatic adenocarcinoma: a North Central Cancer Treatment Group phase II trial

scientific article published in December 2004

Gemcitabine and irinotecan as first-line therapy for carcinoma of unknown primary: results of a multicenter phase II trial

scientific article

Gene expression profiling identifies responsive patients with cancer of unknown primary treated with carboplatin, paclitaxel, and everolimus: NCCTG N0871 (alliance)

scientific article

Growth and characterization of multicellular tumor spheroids of human bladder carcinoma origin

scientific article published on 01 August 1986

HER receptor signaling confers resistance to the insulin-like growth factor-I receptor inhibitor, BMS-536924.

scientific article published on 02 September 2008

Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine

scientific article published on 22 March 2005

Heat shock protein inhibitors increase the efficacy of measles virotherapy

scientific article

Heterogeneous role of caspase-8 in fenretinide-induced apoptosis in epithelial ovarian carcinoma cell lines

scientific article published on December 2003

High-performance liquid chromatographic measurement of cyclophosphamide in serum

scientific article published on 01 January 1984

ICI D1694 and idoxuridine: a synergistic antitumor combination.

scientific article published on July 1994

In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417.

scientific article published on January 2006

Irinotecan in the treatment of glioma patients: current and future studies of the North Central Cancer Treatment Group

scientific article published on May 2003

Irinotecan plus 5-FU and leucovorin in advanced colorectal cancer: North American trials

scientific article published on 01 August 1998

Large cell carcinoma with calcitonin and vasoactive intestinal polypeptide-associated Verner-Morrison syndrome

scientific article published in January 2005

Levamisole and 5-fluorouracil therapy for resected colon cancer: a new indication

scientific article

Limitations of urinary mutagen assays for monitoring occupational exposure to antineoplastic drugs

scientific article published in February 1986

Limited sampling models for CPT-11, SN-38, and SN-38 glucuronide

scientific article

Male breast cancer: a 13-year review of 89 patients ⬇️

scientific article published on August 1, 1984

Male breast cancer: an 11 year review of 66 patients

scientific article published on January 1996

Medical management of pancreatic neuroendocrine tumors

scientific article

Metastatic non-small cell lung carcinoma with involvement of extremity musculature: case report and review of the literature

scientific article

Microsatellite Instability in Patients With Stage III Colon Cancer Receiving Fluoropyrimidine With or Without Oxaliplatin: An ACCENT Pooled Analysis of 12 Adjuvant Trials

scientific article published on 23 December 2020

Mitomycin C pharmacokinetics in patients with recurrent or metastatic colorectal carcinoma

scientific article

Modulation of the equilibrative nucleoside transporter by inhibitors of DNA synthesis.

scientific article published on October 1995

Molecular markers in male breast carcinoma

scientific article published in November 1998

Multicenter Phase II Trial of Temsirolimus and Bevacizumab in Pancreatic Neuroendocrine Tumors

scientific article published on 8 December 2014

Multicenter phase II study of the AKT inhibitor MK-2206 in recurrent or metastatic nasopharyngeal carcinoma from patients in the mayo phase II consortium and the cancer therapeutics research group (MC1079).

scientific article published on 19 June 2015

Necrosis in a meningioma following systemic chemotherapy. Case report

scientific article published on 01 August 1994

New treatment options for colorectal cancer

scientific article

Novel agents in colorectal cancer

scientific article published on 01 January 2001

Novel chemotherapeutic agents in clinical development ⬇️

scientific article published on December 1, 1991

Novel therapeutics in colorectal cancer

scientific article

Open-label, dose-escalation, safety, pharmacokinetic, and pharmacodynamic study of intravenously administered CNF1010 (17-(allylamino)-17-demethoxygeldanamycin [17-AAG]) in patients with solid tumors ⬇️

scientific article published on April 6, 2013

Optimal duration of fluorouracil plus levamisole colon cancer surgical adjuvant therapy

scientific article published on 01 October 1996

Optimum doses of irinotecan

scientific article published on 01 April 1999

Oxaliplatin in the treatment of colorectal cancer

scientific article published on April 2007

P-100Phase IB study of sorafenib + evofosfamide in patients (pts) with advanced hepatocellular carcinoma (HCC) and renal cell carcinoma (RCC): NCCTG N1153 (Alliance).

scientific article published on 21 June 2016

P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response

scientific article published on September 2008

Pathogenesis and risk factors of small bowel adenocarcinoma: a colorectal cancer sibling?

scientific article (publication date: March 2005)

Patients' willingness to enter clinical trials: measuring the association with perceived benefit and preference for decision participation

scientific article published in January 1991

Peripheral leukocytes as indicators of the enzymatic effects of N-(phosphonacetyl)-L-aspartic acid (PALA) on human L-aspartate transcarbamoylase (ATCase) activity

scientific article published on 01 August 1980

Phase 1 study of interleukin-12 in combination with rituximab in patients with B-cell non-Hodgkin lymphoma ⬇️

scientific article published on 01 January 2002

Phase 1 study of sorafenib in combination with bortezomib in patients with advanced malignancies.

scientific article published on 26 July 2013

Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer

scientific article published on 21 November 2019

Phase 1 trial of flavopiridol combined with cisplatin or carboplatin in patients with advanced malignancies with the assessment of pharmacokinetic and pharmacodynamic end points.

scientific article published on August 2005

Phase 2 study of bevacizumab plus erlotinib in patients with advanced hepatocellular cancer ⬇️

scientific article published on September 27, 2011

Phase 2 trial of daily, oral Polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia

scientific article published on 03 July 2012

Phase I and pharmacokinetic study of fostriecin given as an intravenous bolus daily for five consecutive days

scientific article

Phase I and pharmacokinetic study of irinotecan and docetaxel in patients with advanced solid tumors: preliminary evidence of clinical activity

scientific article published on 01 March 2000

Phase I and pharmacokinetic study of two different schedules of oxaliplatin, irinotecan, Fluorouracil, and leucovorin in patients with solid tumors

scientific article published on 8 September 2003

Phase I and pharmacologic study of infusional topotecan and Carboplatin in relapsed and refractory acute leukemia

scientific article

Phase I and pharmacologic study of sequences of gemcitabine and the multitargeted antifolate agent in patients with advanced solid tumors

scientific article published on 01 April 2000

Phase I and pharmacological study of cytarabine and tanespimycin in relapsed and refractory acute leukemia

scientific article published on 26 July 2011

Phase I and pharmacological trial of fazarabine (Ara-AC) with granulocyte colony-stimulating factor.

scientific article published in December 1997

Phase I dose escalation study of the PKCι inhibitor aurothiomalate for advanced non-small-cell lung cancer, ovarian cancer, and pancreatic cancer.

scientific article

Phase I dose-finding and pharmacokinetic trial of irinotecan hydrochloride (CPT-11) using a once-every-three-week dosing schedule for patients with advanced solid tumor malignancy.

scientific article published in June 2000

Phase I pharmacokinetic and pharmacodynamic study of 17-dimethylaminoethylamino-17-demethoxygeldanamycin, an inhibitor of heat-shock protein 90, in patients with advanced solid tumors

scientific article

Phase I pharmacokinetic and pharmacodynamic study of a new anthrapyrazole, CI-937 (DUP937).

scientific article

Phase I pharmacokinetic study of cyclosporin A combined with doxorubicin

scientific article

Phase I study of 17-allylamino-17 demethoxygeldanamycin, gemcitabine and/or cisplatin in patients with refractory solid tumors

scientific article

Phase I study of EKB-569, an irreversible inhibitor of the epidermal growth factor receptor, in patients with advanced solid tumors

scientific article published on 01 May 2006

Phase I study of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with relapsed and refractory B-cell non-Hodgkin lymphoma

scientific article

Phase I study of tanespimycin in combination with bortezomib in patients with advanced solid malignancies ⬇️

scientific article published on March 31, 2013

Phase I study of temsirolimus in combination with EKB-569 in patients with advanced solid tumors

scientific article

Phase I study of the duocarmycin semisynthetic derivative KW-2189 given daily for five days every six weeks ⬇️

scientific article published on September 1, 1998

Phase I study of the matrix metalloproteinase inhibitor, BAY 12-9566.

scientific article

Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer

scientific article published on 01 February 2005

Phase I trial of FOLFIRI in combination with sorafenib and bevacizumab in patients with advanced gastrointestinal malignancies

scientific article published on 18 November 2015

Phase I trial of N-(phosphonacetyl)-L-aspartate ⬇️

scientific article published on October 1, 1979

Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia

scientific article published on 26 May 2009

Phase I trial of dolastatin-10 (NSC 376128) in patients with advanced solid tumors

scientific article published on 01 March 1999

Phase I trial of everolimus, gemcitabine and cisplatin in patients with solid tumors

scientific article

Phase I trial of gemcitabine and CPT-11 given weekly for four weeks every six weeks

scientific article

Phase I trial of sequential administration of raltitrexed (Tomudex) and 5-iodo-2'-deoxyuridine (IdUrd).

scientific article

Phase I, pharmacokinetic study of temsirolimus administered orally to patients with advanced cancer.

scientific article published on 5 May 2009

Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas

scientific article

Phase I-phase II trial of N-phosphonacetyl-L-aspartic acid given by intravenous infusion and 5-fluorouracil given by bolus injection

scientific article published on 01 February 1982

Phase I/II trial of granisetron: a novel 5-hydroxytryptamine antagonist for the prevention of chemotherapy-induced nausea and vomiting

scientific article published on 01 February 1990

Phase II study of Erlotinib (OSI-774) in patients with advanced hepatocellular cancer

scientific article

Phase II study of daily oral perifosine in patients with advanced soft tissue sarcoma

scientific article published in November 2006

Phase II study of erlotinib in patients with advanced biliary cancer

scientific article

Phase II study of the farnesyl transferase inhibitor R115777 in patients with advanced non-small-cell lung cancer

scientific article published on May 2003

Phase II study of the histone deacetylase inhibitor belinostat (PXD101) for the treatment of myelodysplastic syndrome (MDS) ⬇️

scientific article published on May 3, 2011

Phase II trial of 5-fluorouracil and folinic acid in the treatment of advanced breast cancer

scientific article published on 01 January 1994

Phase II trial of diaziquone in patients with colon cancer

scientific article published on 01 February 1985

Phase II trial of gemcitabine and tanespimycin (17AAG) in metastatic pancreatic cancer: a Mayo Clinic Phase II Consortium study.

scientific article published on 08 May 2015

Phase II trial of oxaliplatin/irinotecan/5-fluorouracil/leucovorin for metastatic colorectal cancer

scientific article published on May 2007

Phase II trials of single-agent anti-VEGF therapy for patients with chronic lymphocytic leukemia ⬇️

scientific article published on November 5, 2010

Plasma pharmacokinetics of 5-FU given by continuous infusion with allopurinol

scientific article published on 01 July 1986

Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells.

scientific article

Potential applications of therapeutic drug monitoring in treatment of neoplastic disease by antineoplastic agents

scientific article

Profound hair and skin hypopigmentation in an African American woman treated with the multi-targeted tyrosine kinase inhibitor pazopanib.

scientific article published in June 2010

Prognostic factors in patients with metastatic colorectal cancer receiving 5-fluorouracil and folinic acid

scientific article published on 01 January 1992

Prospectively randomized trial of postoperative adjuvant chemotherapy in patients with high-risk colon cancer ⬇️

scientific article published on 01 January 1998

RECPAM analysis of prognostic factors in patients with stage III breast cancer

scientific article published on October 1990

Randomized phase II study of interleukin-12 in combination with rituximab in previously treated non-Hodgkin's lymphoma patients

scientific article published on 01 October 2006

Rapid development of enhanced clearance after high-dose cyclophosphamide

scientific article published on 01 December 1988

Resistance of MGH-U1 bladder cancer spheroids to vincristine.

scientific article

Review of 154 patients with non-functioning pituitary tumors ⬇️

scientific article published on November 1, 1979

Safety and activity of temsirolimus and bevacizumab in patients with advanced renal cell carcinoma previously treated with tyrosine kinase inhibitors: a phase 2 consortium study

scientific article

Sequential methotrexate-fluorouracil: the role of leucovorin in improving tumor response

scientific article published in August 1986

Serum uridine levels in patients receiving N-(phosphonacetyl)-L-aspartate

scientific article published on 01 August 1980

Small bowel adenocarcinoma: a rare but aggressive disease

scientific article

Somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine tumors

scientific article

Superiority of Granisetron to Dexamethasone Plus Prochlorperazine in the Prevention of Chemotherapy-Induced Emesis ⬇️

scientific article published on August 21, 1991

Superiority of methylprednisolone sodium succinate over low dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy

scientific article published on November 1986

Synergy of the protein farnesyltransferase inhibitor SCH66336 and cisplatin in human cancer cell lines.

scientific article published on May 2001

Tanespimycin: the opportunities and challenges of targeting heat shock protein 90.

scientific article published on June 2009

Targeting of the Hedgehog/GLI and mTOR pathways in advanced pancreatic cancer, a phase 1 trial of Vismodegib and Sirolimus combination

scientific article published on 14 July 2020

Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study

scientific article

The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux

scientific article

The Hsp90 chaperone complex as a novel target for cancer therapy

scientific article

The clinical case for proton beam therapy.

scientific article published on 22 October 2012

The practical benefits of pharmacokinetics in the use of antineoplastic agents

scientific article published on January 1980

The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons

scientific article

Therapeutic drug monitoring in oncology. Problems and potential in antineoplastic therapy

scientific article published on October 1987

Treatment of advanced gastric carcinoma with mitomycin and doxorubicin.

scientific article published in July 1986

UGT1A1 genotype-guided phase I study of irinotecan, oxaliplatin, and capecitabine

scientific article published on 10 October 2013

Up-regulation of heat shock protein 27 induces resistance to 17-allylamino-demethoxygeldanamycin through a glutathione-mediated mechanism

scientific article published on November 2006

Variability in the pharmacokinetics of cyclophosphamide, methotrexate and 5-fluorouracil in women receiving adjuvant treatment for breast cancer

scientific article published on 01 January 1994

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