Search filters

List of works by Miriam C. Poirier

3'-azido-3'-deoxythymidine (AZT) transplacental perfusion kinetics and DNA incorporation in normal human placentas perfused with AZT

scientific article published on 01 July 1999

A pilot project in molecular cancer epidemiology: determination of benzo[a]pyrene — DNA adducts in animal and human tissues by immunoassays ⬇️

scientific article published on January 1, 1982

Absence of structural or functional alterations in male and female reproductive organs of F1 and F2 generations derived from female mice exposed to 3'-azido-3'-deoxythymidine during pregnancy

scientific article published in April 2000

Abundant expression of CYP1A1 is positively, while CYP1B1 and NQ01 are negatively, associated with benzo(a)pyrene (BP)-DNA adduct formation in normal human mammary epithelial cells (NHMECs)

conference abstract published in 2008

Achieving professional success in US government, academia, and industry: an EMGS commentary

scientific article published on 2 May 2014

Antibodies elicited against cis-diamminedichloroplatinum(II)-modified DNA are specific for cis-diamminedichloroplatinum(II)-DNA adducts formed in vivo and in vitro

scientific article

Antibodies to carcinogen-DNA adducts

scientific article published on 01 September 1981

Antiretroviral activity of aminothiols, WR2721 and WR1065.

scientific article

Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo

scientific article

Antisera specific for carcinogen-DNA adducts and carcinogen-modified DNA: Applications for detection of xenobiotics in biological samples ⬇️

scientific article published on July 1, 1993

Aromatic amine DNA adduct formation in chronically-exposed mice: considerations for human comparison

scientific article published in May 1997

Assessment of multiple types of DNA damage in human placentas from smoking and nonsmoking women in the Czech Republic

scientific article

Association between GSTM1*0 and squamous dysplasia of the esophagus in the high risk region of Linxian, China

journal article published in 2000

Association between zidovudine-containing antiretroviral therapy exposure in utero and leukocyte telomere length at birth

scientific article published on 01 November 2019

Association of PAH-DNA adducts in peripheral white blood cells with dietary exposure to polyaromatic hydrocarbons

scientific article

Base pairing and template specificity during deoxyribonucleic acid repair synthesis in human and mouse cells ⬇️

scientific article published on December 17, 1974

Benzo(a)pyrene (BP)-DNA adduct reduction in the presence of chlorophyllin (CHL) is independent of BP-metabolizing cytochrome P450 induction in human MCL-5 cells

conference abstract published in 2005

Benzo(a)pyrene-DNA adduct formation and removal in mouse epidermis in vivo and in vitro: relationship of DNA binding to initiation of skin carcinogenesis ⬇️

scientific article published on September 1, 1984

Benzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days

scientific article

Benzo[alpha]pyrene diol epoxide I binds to DNA at replication forks

scientific article

Biological monitoring of fire fighters: sister chromatid exchange and polycyclic aromatic hydrocarbon-DNA adducts in peripheral blood cells.

scientific article published in September 1989

Biomarkers of carcinogen exposure and cancer risk in a coke plant

scientific article

Biomarkers of human exposure to carcinogens: an overview.

scientific article published on June 1991

Biomonitoring of United States Army soldiers serving in Kuwait in 1991 ⬇️

scientific article published on June 1, 1998

Biomonitoring of cisplatin-DNA adducts in cancer patients receiving cisplatin chemotherapy

scientific article published on 01 January 1986

Biomonitoring of genotoxic exposure in aluminium plant workers by determination of DNA adducts in human peripheral blood lymphocytes

scientific article published on 01 February 1995

Biomonitoring of human genotoxicity induced by complex occupational exposures

scientific article published on 01 September 1999

Biphasic removal of DNA adducts in a repetitive DNA sequence after dietary administration of 2-acetylaminofluorene

scientific article

CYP1A1 and CYP1B1 gene expression and DNA adduct formation in normal human mammary epithelial cells exposed to benzo[a]pyrene in the absence or presence of chlorophyllin

journal article published in 2010

Carcinogen macromolecular adducts

book or book chapter published in 2001

Carcinogen macromolecular adducts and their measurement ⬇️

journal article published in 2000

Carcinogen-DNA adduct formation and DNA repair

chapter published in 2005

Carcinogen-induced alterations in rat liver DNA adduct formation determined by computerized fluorescent image analysis

scientific article

Carcinogens and DNA damage

scientific article published in 2018

Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors

scientific article published in January 2005

Cardiomyocytes are Protected from Antiretroviral Nucleoside Analog-Induced Mitochondrial Toxicity by Overexpression of PGC-1α.

scientific article

Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells

scientific article

Centrosome amplification induced by the antiretroviral nucleoside reverse transcriptase inhibitors lamivudine, stavudine, and didanosine

scientific article

Characterization of the DNA damage recognized by an antiserum elicited against cis-diamminedichloroplatinum (II)-modified DNA.

scientific article published in December 1990

Chemical carcinogenesis: from animal models to molecular models in one decade

scientific article published on January 1988

Chemical-induced DNA damage and human cancer risk

scientific article published in August 2004

Chemical-induced DNA damage and human cancer risk

scientific article published on 01 October 2012

Chlorophyllin differentially modulates CYP1 gene expression in normal human mammary epithelial cells (NHMECs) exposed to benzopyrenes ⬇️

conference abstract published in 2006

Chlorophyllin modulates gene expression and DNA-adduct formation in normal human mammary epithelial cells (NHMECs) exposed to benzo(a)pyrene (BP) ⬇️

conference abstract published in 2005

Chlorophyllin significantly reduces benzo[a]pyrene-DNA adduct formation and alters cytochrome P450 1A1 and 1B1 expression and EROD activity in normal human mammary epithelial cells

journal article published in 2009

Chlorophyllin treatment reduces benzo[a]pyrene (BP)-induced CYP1A1 and CYP1B1 expression and BP-DNA adduct formation in normal human mammary epithelial cells (NHMECs) ⬇️

conference abstract published in 2004

Chromosome site-specific immunohistochemical detection of DNA adducts in N-acetoxy-2-acetylaminofluorene--exposed Chinese hamster ovary cells

scientific article

Chronic stavudine exposure induces hepatic mitochondrial toxicity in adult Erythrocebus patas monkeys

scientific article published in November 2001

Cisplatin exposure induces mitochondrial toxicity in pregnant rats and their fetuses

scientific article published on 01 September 2001

Cisplatin-DNA adduct formation in maternal and fetal rat tissues after transplacental cisplatin exposure

scientific article published in August 1996

Cisplatin-DNA damage in p21WAF1/Cip1 deficient mouse keratinocytes exposed to cisplatin

scientific article published on 8 December 2006

Cisplatin−DNA Adduct Determination in the Hepatic Albumin Gene as Compared to Whole Genomic DNA ⬇️

scientific article published on September 1, 1997

Comparison between DNA adduct formation and tumorigenesis in livers and bladders of mice chronically fed 2-acetylaminofluorene.

scientific article published in May 1991

Continuous exposure to the carcinogenic antiretroviral drug Zidovudine (AZT) alters metabolism of human cells in vitro ⬇️

conference abstract published in 2005

Contribution of occupation and diet to white blood cell polycyclic aromatic hydrocarbon-DNA adducts in wildland firefighters

scientific article published in July 1993

Correlation between CYP1A1 RNA transcript, protein level, enzyme activity, and DNA adducts in primary normal human mammary epithelial cells exposed to benzo[a]pyrene

abstract published in 2014

Correlation between CYP1A1 transcript, protein level, enzyme activity and DNA adduct formation in normal human mammary epithelial cell strains exposed to benzo[a]pyrene

journal article published in 2014

DNA adduct determination in humans.

scientific article published on January 1991

DNA adduct formation and aromatic amine tumorigenesis

scientific article published on 01 January 1992

DNA adduct formation and removal during chronic administration of a carcinogenic aromatic amine

scientific article published on 01 January 1987

DNA adduct formation and removal in N-acetoxy-2-acetylaminofluorene-exposed cultured cells and in organs from rats fed 2-acetylaminofluorene

scientific article published on 01 January 1983

DNA adduct formation and removal in hepatic chromatin fractions from rats chronically fed 2-acetylaminofluorene

scientific article published on August 1990

DNA adduct formation and removal in specific liver cell populations during chronic dietary administration of 2-acetylaminofluorene.

scientific article published in June 1989

DNA adduct formation and tumorigenesis in mice during the chronic administration of 4-aminobiphenyl at multiple dose levels.

scientific article

DNA adduct formation during continuous feeding of 2-acetylaminofluorene at multiple concentrations

scientific article published on 01 January 1988

DNA adduct formation in human and rat mammary epithelium by N-hydroxy derivatives of 2-aminofluorene and 4-aminobiphenyl ⬇️

scientific article published on January 1, 1998

DNA adduct formation in relation to tumorigenesis in mice chronically fed 2-acetylaminofluorene

scientific article published on 01 January 1990

DNA adduct formation in relation to tumorigenesis in mice continuously administered 4-aminobiphenyl

scientific article published on 01 January 1990

DNA adduct formation, removal and persistence in rat liver during one month of feeding 2-acetylaminofluorene.

scientific article

DNA adduct measurements and tumor incidence during chronic carcinogen exposure in animal models: implications for DNA adduct-based human cancer risk assessment.

scientific article published on November 1992

DNA adduct measurements and tumor incidence during chronic carcinogen exposure in rodents

scientific article

DNA adducts as exposure biomarkers and indicators of cancer risk ⬇️

scientific article published on June 1, 1997

DNA adducts in human and patas monkey maternal and fetal tissues induced by platinum drug chemotherapy.

scientific article

DNA adducts in peripheral blood lymphocytes from aluminum production plant workers determined by 32P-postlabeling and enzyme-linked immunosorbent assay

scientific article

DNA adducts in tumour, normal peripheral lung and bronchus, and peripheral blood lymphocytes from smoking and non-smoking lung cancer patients: correlations between tissues and detection by 32P-postlabelling and immunoassay

scientific article published on 4 March 2004

DNA adducts induced by platinum drug chemotherapeutic agents in human tissues

scientific article published on 01 January 1992

DNA adducts of cisplatin and carboplatin in tissues of cancer patients

scientific article published on 01 January 1988

DNA adducts of cisplatin in nucleated peripheral blood cells and tissues of cancer patients

scientific article published on 01 January 1987

DNA adducts, protein adducts, and sister chromatid exchange in cigarette smokers and nonsmokers.

scientific article

DNA damage, DNA repair, and mutagenesis

book or book chapter published in 2002

Deoxyribonucleoside incorporation during DNA repair of carcinogen-induced damage in human diploid fibroblasts

scientific article published on 01 September 1973

Derivative fluorescence spectral analysis of polycyclic aromatic hydrocarbon-DNA adducts in human placenta.

scientific article published in March 1989

Detection and quantitation of acetylated and deacetylated N-2-fluorenylacetamide-DNA adducts by radioimmunoassay

scientific article published on December 1981

Detection of carcinogen-DNA adducts by radiommunoassay

scientific article published on November 10, 1977

Detection of polycyclic aromatic hydrocarbon-DNA adducts in human lung

scientific article

Determination of 2-acetylaminofluorene adducts by immunoassay

scientific article

Determination of carcinogen-DNA adducts by immunoassay.

scientific article

Determination of carcinogen-induced macromolecular adducts in animals and humans

scientific article published on 01 January 1987

Development and validation of a direct sandwich chemiluminescence immunoassay for measuring DNA adducts of benzo[a]pyrene and other polycyclic aromatic hydrocarbons ⬇️

scientific article published on May 18, 2012

Dietary induction of some enzymes of carbohydrate metabolism during 2-acetylaminofluorene feeding

scientific article published on 01 February 1969

Distribution of deoxyribonucleic acid repair synthesis among repetitive and unique sequences in the human diploid genome ⬇️

scientific article published on July 16, 1974

Dosimeters of human exposure to carcinogens: polycyclic aromatic hydrocarbon-macromolecular adducts.

scientific article

EMGS at 50 Years: Current Status and New Directions

scientific article published on 29 July 2019

Effect of culture conditions, cell type, and species of origin on the distribution of acetylated and deacetylated deoxyguanosine C-8 adducts of N-acetoxy-2-acetylaminofluorene

scientific article published in November 1980

Effects of carcinogen treatment on rat liver DNA synthesis in vivo and on nascent DNA synthesis and elongation in cultured hepatocytes.

scientific article published in July 1986

Elevated mitochondrial cisplatin-DNA adduct levels in rat tissues after transplacental cisplatin exposure.

scientific article published in January 1997

Enhanced malignant conversion of benign mouse skin tumors by cisplatin

scientific article published in May 1990

Erratum to “Polycyclic aromatic hydrocarbon-DNA adducts determined by semiquantitative immunohistochemistry in human esophageal biopsies taken in 1985” [Mutat. Res. 547 (2004) 55–62]

scholarly article published in Mutation Research

Erythrocebus patas monkey offspring exposed perinatally to NRTIs sustain skeletal muscle mitochondrial compromise at birth and at 1 year of age.

scientific article published in June 2007

Evaluation of platinum-DNA adduct levels relative to known prognostic variables in a cohort of ovarian cancer patients

scientific article published on 01 April 1990

Exposure of Allium cepa root cells to zidovudine or nevirapine induces cytogenotoxic changes

scientific article (publication date: 2014)

Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and 32P-postlabelling.

scientific article

Fetal consequences of maternal antiretroviral nucleoside reverse transcriptase inhibitor use in human and nonhuman primate pregnancy

scientific article

Fetal mitochondrial heart and skeletal muscle damage in Erythrocebus patas monkeys exposed in utero to 3'-azido-3'-deoxythymidine

scientific article

Fetal patas monkeys sustain mitochondrial toxicity as a result of in utero zidovudine exposure

scientific article published on 01 November 2000

Formation and removal of (guan-8-yl)-DNA-2-acetylaminofluorene adducts in liver and kidney of male rats given dietary 2-acetylaminofluorene

scientific article published on 01 April 1982

Formation and removal of specific acetylaminofluorene-DNA adducts in mouse and human cells measured by radioimmunoassay ⬇️

scientific article published on April 1, 1979

Formation of polycyclic aromatic hydrocarbon-DNA adducts in peripheral white blood cells during consumption of charcoal-broiled beef

scientific article published in July 1990

Formation of tamoxifen-DNA adducts in multiple organs of adult female cynomolgus monkeys dosed with tamoxifen for 30 days ⬇️

scientific article published on September 15, 2003

Gene expression and DNA adduct formation is modulated by chlorophyllin in normal human mammary epithelial cells exposed to benzo(a)pyrene (BP)

conference abstract published in 2005

Genomic instability induced by AZT in cultured normal human mammary epithelial cells (NHMECs) generates aneuploidy.

scientific article

Genotoxic and functional consequences of transplacental zidovudine exposure in fetal monkey brain mitochondria

scientific article published on 01 June 2000

Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.

scientific article published on April 2007

Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT

scientific article

Hepatic DNA adduct dosimetry in rats fed tamoxifen: a comparison of methods.

scientific article

High-performance liquid chromatography electrospray ionization tandem mass spectrometry for the detection and quantitation of benzo[a]pyrene-DNA adducts

journal article published in 2005

Highly sensitive chemiluminescence immunoassay for benzo[a]pyrene-DNA adducts: validation by comparison with other methods, and use in human biomonitoring

scientific article

Human DNA adduct measurements: state of the art

scientific article

Human exposure monitoring, dosimetry, and cancer risk assessment: the use of antisera specific for carcinogen-DNA adducts and carcinogen-modified DNA.

scientific article published on January 1994

Human inter-individual variability in metabolic pathways and genotoxic response to zidovudine ⬇️

conference abstract published in 2006

Human inter-individual variability in metabolism and genotoxic response to zidovudine

journal article published in 2008

Human placental glutathione S-transferase activity and polycyclic aromatic hydrocarbon DNA adducts as biomarkers for environmental oxidative stress in placentas from pregnant women living in radioactivity- and chemically-polluted regions

scientific article

Identification of tamoxifen-DNA adducts in monkeys treated with tamoxifen.

scientific article published in August 2003

Immunohistochemical and microfluorometric determination of hepatic DNA adduct removal in rats fed 2-acetylaminofluorene.

scientific article published on November 1994

Immunohistochemical localization and semi-quantitation of hepatic tamoxifen-DNA adducts in rats exposed orally to tamoxifen

scientific article

Immunohistochemical localization of DNA adducts in rat liver tissue and phenotypically altered foci during oral administration of 2-acetylaminofluorene

scientific article published on 01 January 1986

In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue

scientific article

In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue

scientific article

In vivo localization and postmortem stability of benzo[a]pyrene-DNA adducts

scientific article published on 25 October 2019

Incorporation of 3'-azido-3'-deoxythymidine (AZT) into fetal DNA and fetal tissue distribution of drug after infusion of pregnant late-term rhesus macaques with a human-equivalent AZT dose

scientific article published on 01 December 1999

Incorporation of zidovudine into cord blood DNA of infants and peripheral blood DNA of their HIV-1-positive mothers

scientific article published on 01 November 2000

Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero

scientific article

Increased sensitivity for determination of polycyclic aromatic hydrocarbon-DNA adducts in human DNA samples by dissociation-enhanced lanthanide fluoroimmunoassay (DELFIA).

scientific article published in July 1993

Indirect immunofluorescent localization of benzo[a]pyrene adducted to nucleic acids in cultured mouse keratinocyte nuclei

scientific article published on 01 January 1982

Induction of CYP1A1 and CYP1B1 and formation of carcinogen - DNA adducts in normal human mammary epithelial cells treated with benzo[a]pyrene

journal article published in 2005

Inhibition by gonadectomy of effects of 2-acetylaminofluorene in livers of male, but not female rats.

scientific article published in September 1993

Interindividual differences in the concentration of 1-hydroxypyrene-glucuronide in urine and polycyclic aromatic hydrocarbon-DNA adducts in peripheral white blood-cells after charbroiled beef consumption

journal article published in 1995

Interlaboratory comparison of antisera and immunoassays for benzo[a]pyrene-diol-epoxide-I-modified DNA.

scientific article

Intestinal polycyclic aromatic hydrocarbon-DNA adducts in a population of beluga whales with high levels of gastrointestinal cancers

article

Intragenomal Distribution of DNA Repair Synthesis: Repair in Satellite and Mainband DNA in Cultured Mouse Cells ⬇️

scientific article published on June 1, 1974

Lack of acetylaminofluorene--DNA adduct formation in enzyme-altered foci of rat liver.

scientific article

Leukocyte polycyclic aromatic hydrocarbon-DNA adduct formation and colorectal adenoma

scientific article published on 2 February 2007

Linking DNA adduct formation and human cancer risk in chemical carcinogenesis

scientific article

Localization of DNA adducts induced by N-acetoxy-N-2-acetylaminofluorene in chinese hamster ovary cells using electron microscopy and colloidal gold ⬇️

scientific article published on July 1, 1990

Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells

scientific article

Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers

scientific article published on 01 June 2003

Measurement of DNA adducts by immunoassays

scientific article published on January 1990

Measurement of benzo(a)pyrene-DNA adducts by enzyme immunoassays and radioimmunoassay

scientific article published on 01 March 1981

Metabolism and pharmacokinetics of the combination Zidovudine plus Lamivudine in the adult Erythrocebus patas monkey determined by liquid chromatography-tandem mass spectrometric analysis

scientific article published on 18 September 2007

Methods of DNA adduct determination and their application to testing compounds for genotoxicity

scientific article published on 01 January 2000

Microfluorometric determination of DNA adducts in immunofluorescent-stained liver tissue from rats fed 2-acetylaminofluorene.

scientific article published in April 1987

Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies

scientific article published on 25 July 2016

Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir

scientific article published in April 2004

Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine

scientific article published in January 2004

Modulation of CYP1A1 and CYP1B1 expression by chlorophyllin in normal human mammary epithelial cells exposed to benzo(a)pyrene

abstract published in 2004

Molecular analysis of mitochondrial compromise in rodent cardiomyocytes exposed long term to nucleoside reverse transcriptase inhibitors (NRTIs).

scientific article

Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long-term to Zidovudine

scientific article published on 01 April 2007

Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice

scientific article

Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations

scientific article published on April 2007

Nonspecific inhibition of DNA repair synthesis by tumor promoters in human diploid fibroblasts damaged with N-acetoxy-2-acetylaminofluorene ⬇️

scientific article published on June 1, 1975

Nuclear bud formation: a novel manifestation of Zidovudine genotoxicity

scientific article

Oxidative DNA damage in fetal tissues after transplacental exposure to 3'-azido-3'-deoxythymidine (AZT)

scientific article published on 01 May 2000

Oxidative stress and p53 mutations in the carcinogenesis of iron overload-associated hepatocellular carcinoma.

scientific article

Para-aminobenzoic acid suppression of cis-diamminedichloroplatinum(II) nephrotoxicity

scientific article published on 01 December 1993

Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age

scientific article published on 04 April 2013

Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs

scientific article published in September 2004

Peripheral Blood Leukocytes as a Surrogate Marker for Cisplatin Drug Resistance: Studies of Adduct Levels and the Repair Gene ERCC1 ⬇️

scientific article published on January 1, 1990

Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine

scientific article published in January 2004

Persistence of platinum-ammine-DNA adducts in gonads and kidneys of rats and multiple tissues from cancer patients

scientific article published in January 1992

Plasma and cellular markers of 3'-azido-3'-dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs

scientific article published on 01 April 2007

Plasma drug levels compared with DNA incorporation of 3'-azido-3'-deoxythymidine (AZT) in adult cynomolgus (Macaca fascicularis) monkeys.

scientific article published in May 2001

Platinum chemotherapy during pregnancy for serous cystadenocarcinoma of the ovary

scientific article published on 01 April 1993

Platinum drug-DNA interactions in human tissues measured by cisplatin-DNA enzyme-linked immunosorbent assay and atomic absorbance spectroscopy

scientific article

Platinum-DNA adducts assayed in leukocytes of patients with germ cell tumors measured by atomic absorbance spectrometry and enzyme-linked immunosorbent assay

scientific article published on June 1994

Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy

scientific article

Polyclonal Antibodies to Quantitate Cis-Diamminedichloroplatinum(II)-DNA Adducts in Cancer Patients and Animal Models

scientific article published on 10 March 2007

Polyclonal antibodies to quantitate cis-diamminedichloroplatinum(II)--DNA adducts in cancer patients and animal models

scientific article

Polycyclic Aromatic Hydrocarbon-DNA Adducts in Gulf of Mexico Sperm Whale Skin Biopsies Collected in 2012

scientific article published on 01 April 2021

Polycyclic aromatic hydrocarbon (PAH) exposure and DNA adduct semi-quantitation in archived human tissues

scientific article

Polycyclic aromatic hydrocarbon biomarkers of internal exposure in US Army soldiers serving in Kuwait in 1991

journal article published in 1999

Polycyclic aromatic hydrocarbon-DNA adducts determined by semiquantitative immunohistochemistry in human esophageal biopsies taken in 1985.

scientific article published on March 2004

Polycyclic aromatic hydrocarbon-DNA adducts in cervix of women infected with carcinogenic human papillomavirus types: an immunohistochemistry study

scientific article

Potential toxicities of HIV therapeutics in the developing infant

scientific article published on 01 May 2000

Preferential binding of cisplatin to mitochondrial DNA of Chinese hamster ovary cells

scientific article published on 01 April 1995

Preferential formation and decreased removal of cisplatin–DNA adducts in Chinese hamster ovary cell mitochondrial DNA as compared to nuclear DNA ⬇️

scientific article published on June 13, 1997

Preferential incorporation of 3'-azido-2',3'-dideoxythymidine into telomeric DNA and Z-DNA-containing regions of Chinese hamster ovary cells

scientific article published on 01 January 1993

Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs)

scientific article

Quantification of phase I/II metabolizing enzyme gene expression and polycyclic aromatic hydrocarbon-DNA adduct levels in human prostate

scientific article (publication date: April 2009)

Quantitation and immunohistochemical localization of DNA adducts in rat embryos and associated yolk sac membranes exposed in vitro to N-acetoxy-2-acetylaminofluorene (N-Ac-AAF)

scientific article published on 01 January 1991

Quantitation by electron microscopy of the binding of highly specific antibodies to benzo[a]pyrene-DNA adducts.

scientific article

Quantitation of benzo(a)pyrene-deoxyguanosine adducts by radioimmunoassay.

scientific article published in February 1980

Quantitation of cis-diamminedichloroplatinum II (cisplatin)-DNA-intrastrand adducts in testicular and ovarian cancer patients receiving cisplatin chemotherapy

scientific article

Radioimmunoassay for 2-acetylaminofluorene-DNA adducts

scientific article published on 01 January 1982

Reduced DNA adduct formation in replicating liver cells during continuous feeding of a chemical carcinogen

scientific article

Reduction in tamoxifen-induced CYP3A2 expression and DNA adducts using antisense technology

journal article published in 2006

Relationship between patient response in ovarian and breast cancer and platinum drug-DNA adduct formation

scientific article published on 01 May 1993

Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine

scientific article

Role of nucleotide excision repair and p53 in zidovudine (AZT)-induced centrosomal deregulation

scientific article

Seasonal variations in the levels of PAH-DNA adducts in young adults living in Mexico City ⬇️

scientific article published on December 30, 2010

Selective protection of zidovudine-induced DNA-damage by the antioxidants WR-1065 and tempol.

scientific article published on 16 May 2014

Semiquantitation of polycyclic aromatic hydrocarbon-DNA adducts in human esophagus by immunohistochemistry and the automated cellular imaging system

scientific article

Significance of DNA adduct studies in animal models for cancer molecular dosimetry and risk assessment

scientific article

Skin tumorigenesis and Ki-ras and Ha-ras mutations in tumors from adult mice exposed in utero to 3′-azido-2′,3′-dideoxythymidine ⬇️

scientific article published on September 1, 1998

Special issue on health risks of perinatal exposure to nucleoside reverse transcriptase inhibitors

scientific article published on 01 April 2007

Specific quantification of mouse and human keratin proteins by radioimmunoassay

scientific article published on April 1980

Subunit structure of the mouse epidermal keratin filament ⬇️

scientific article published on March 27, 1979

Synthesis, Characterization, and Quantitation of a 4-Aminobiphenyl−DNA Adduct Standard

scientific article published on 01 January 1999

Tamoxifen induces expression of immune response-related genes in cultured normal human mammary epithelial cells

journal article published in 2009

Tamoxifen-DNA adduct formation in monkey and human reproductive organs

scientific article published on 05 February 2014

Tamoxifen-DNA adduct formation in rat liver determined by immunoassay and 32P-postlabeling.

scientific article

Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity

scientific article published on 03 March 2014

The enzymology of the formation and interconversion of labile 1-carbon groups in five hepatomas and in Walker tumor 256

scientific article published in June 1972

The genotoxicity of tamoxifen: extent and consequences, Kona, Hawaii, January 23, 2003.

scientific article published on July 2003

The hepatic activities of 1-carbon enzymes during the chronic administration of diethylnitrosamine, 2-acetylaminofluorene, and n,n-dimethyl-4-aminoazobenzene to rats

scientific article published in June 1972

The impact of glutathione s-transferase M1 and cytochrome P450 1A1 genotypes on white-blood-cell polycyclic aromatic hydrocarbon-DNA adduct levels in humans

scientific article published in September 1995

The influence of age on serum concentrations of cardiac troponin I: results in rats, monkeys, and commercial sera

scientific article published on 15 October 2013

The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo

scientific article (publication date: 28 June 2008)

The measurement of cisplatin-DNA adduct levels in testicular cancer patients

scientific article

The resveratrol analogue, 2,3',4,5'-tetramethoxystilbene, does not inhibit CYP gene expression, enzyme activity and benzo[a]pyrene-DNA adduct formation in MCF-7 cells exposed to benzo[a]pyrene ⬇️

scientific article (publication date: September 2011)

The use of antibodies to detect carcinogen - DNA adducts in vivo and in vitro

scientific article published on 01 January 1983

The use of carcinogen-DNA adduct antisera for quantitation and localization of genomic damage in animal models and the human population

scientific article published on January 1984

Thirteenth Aspen Cancer Conference: workshop on mechanisms of toxicity and carcinogenesis

scientific article published on 01 June 1999

Transcriptional signatures of normal human mammary epithelial cells in response to benzo[a]pyrene exposure: a comparison of three microarray platforms

journal article published in 2005

Transplacental Effects of 3'-Azido-2',3'-Dideoxythymidine (AZT): Tumorigenicity in Mice and Genotoxicity in Mice and Monkeys ⬇️

scientific article published on November 5, 1997

Transplacental cisplatin exposure induces persistent fetal mitochondrial and genomic DNA damage in patas monkeys.

scientific article published in January 1997

Transplacental genotoxicity of combined antiretroviral nucleoside analogue therapy in Erythrocebus patas monkeys

scientific article published in April 2002

Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity

scientific article published in April 2007

Ultrasensitive enzymatic radioimmunoassay (USERIA) detects femtomoles of acetylaminofluorene-DNA adducts.

scientific article published in May 1980

Use of Ciliogenesis to Detect Aneugens: The Role of Primary Cilia

scientific article

Vaginal epithelial DNA damage and expression of preneoplastic markers in mice during chronic dosing with tumorigenic levels of 3'-azido-2',3'-dideoxythymidine

scientific article

Variability in interindividual genotoxic responses in normal human mammary epithelial (NHME) cells exposed to zidovudine

conference abstract published in 2003

WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication

scientific article

Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells

scientific article published on 22 March 2005

Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells

scientific article published in November 2000

cis-Diamminedichloroplatinum (II)-DNA adduct formation in renal, gonadal, and tumor tissues of male and female rats.

scientific article published in February 1987

Paulina is supported by:

About Paulina

Help