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List of works by Jacob D McDonald

A comparison of vascular effects from complex and individual air pollutants indicates a role for monoxide gases and volatile hydrocarbons.

scientific article

A novel nonhuman primate model of cigarette smoke-induced airway disease

scientific article

Addition of ketamine to standard-of-care countermeasures for acute organophosphate poisoning improves neurobiological outcomes

scientific article published on 30 August 2018

Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease ⬇️

scientific article published on August 24, 2011

Analysis of butadiene urinary metabolites by liquid chromatography-triple quadrupole mass spectrometry

scientific article published in April 2004

Application for a Newly Developed High-Capacity NOx Denuder: Low-NOx Diesel Transformation Experiments ⬇️

scientific article published on March 1, 2011

Aryl hydrocarbon receptor-mediated activity of particulate organic matter from the Paso del Norte airshed along the U.S.-Mexico border

scientific article

Atmospheric transformation of diesel emissions

scientific article published on 01 April 2010

Carbon capture and sequestration: an exploratory inhalation toxicity assessment of amine-trapping solvents and their degradation products

scientific article published on 28 August 2014

Cardiopulmonary response to inhalation of biogenic secondary organic aerosol

scientific article published in February 2010

Cardiopulmonary response to inhalation of secondary organic aerosol derived from gas-phase oxidation of toluene

article

Cardiovascular effects of inhaled diesel exhaust in spontaneously hypertensive rats

scientific article published in January 2003

Changes in HPBMC markers of immmune function following controlled short-term inhalation exposures of humans to hardwood smoke.

scientific article published in February 2016

Characterization of Fine Particle Material in Ambient Air and Personal Samples from an Underground Mine

journal article; published in Aerosol Science and Technology in 2002

Characterization of respiratory deposition of fluticasone-salmeterol hydrofluoroalkane-134a and hydrofluoroalkane-134a beclomethasone in asthmatic patients ⬇️

scientific article published on 01 March 2012

Cigarette smoke suppresses Th1 cytokine production and increases RSV expression in a neonatal model.

scientific article published on 26 August 2005

Cochlear function in mice following inhalation of brevetoxin-3.

scientific article

Comparative disposition of dimethylaminoethanol and choline in rats and mice following oral or intravenous administration

scientific article published on 14 May 2019

Comparative effects of parent and heated cinnamaldehyde on the function of human iPSC-derived cardiac myocytes

scientific article published on 10 September 2019

Comparison of inhalation toxicity studies of gentamicin in rats and dogs

scientific article published in November 2013

Composition, toxicity, and mutagenicity of particulate and semivolatile emissions from heavy-duty compressed natural gas-powered vehicles

scientific article published on 23 June 2005

Concentration and particle size of airborne toxic algae (brevetoxin) derived from ocean red tide events

scientific article published on May 2005

Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity

scientific article published on 27 December 2016

Considerations for therapeutic intervention models of pulmonary fibrosis

scientific article published on 14 August 2013

Corrigendum to "Immunotoxicity and biodistribution analysis of arsenic trioxide in C57B1/6 mice following a 2-week inhalation exposure": [Toxicol. Appl. Pharmacol. 241 (2009) 253-259].

scientific article published on August 2010

Dermal and ocular exposure systems for the development of models of sulfur mustard-induced injury ⬇️

scientific article published on 08 April 2011

Design, Characterization, and Evaluation of a Small-Scale Diesel Exhaust Exposure System

journal article; published in Aerosol Science and Technology in 2004

Determination of N2-hydroxymethyl-dG adducts in the nasal epithelium and bone marrow of nonhuman primates following 13CD2-formaldehyde inhalation exposure

scientific article published on 11 January 2011

Diesel particulate material binds and concentrates a proinflammatory cytokine that causes neutrophil migration

scientific article published on January 2004

Disposition and Metabolism of 2,2'-Dimorpholinodiethyl Ether in Sprague Dawley Rats and B6C3F1/N Mice after Oral, Intravenous Administration, and Dermal Application

scientific article published on 05 June 2020

Disposition and clearance of tungsten after single-dose oral and intravenous exposure in rodents

scientific article published on 01 May 2007

Disposition and metabolism of 2',2'"-Dithiobisbenzanilide in rodents following intravenous and oral administration and dermal application

scientific article published on 23 July 2020

Disposition and metabolism of cumene in F344 rats and B6C3F1 mice ⬇️

scientific article published on November 23, 2010

Disposition of fullerene C60 in rats following intratracheal or intravenous administration

scientific article published on 12 April 2019

Disposition of orally and intravenously administered methyltetrahydrofuran in rats and mice

scientific article published on 01 April 2007

Disposition of β-N-methylamino-l-alanine (L-BMAA), a neurotoxin, in rodents following a single or repeated oral exposure

scientific article published on 14 December 2017

Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension

scientific article published on June 2016

Effect of Allergen Inhalation on Airway Oxidant Stress, Using Exhaled Breath Condensate 8-Isoprostane, in Mild Asthma ⬇️

scientific article published on April 10, 2013

Effect of cigarette smoke on autoimmunity in murine and human systemic lupus erythematosus.

scientific article published on 9 June 2005

Effects of concentrated ambient particles and diesel engine exhaust on allergic airway disease in Brown Norway rats.

scientific article

Effects of gasoline engine emissions on preexisting allergic airway responses in mice

Effects of hardwood smoke exposure on allergic airway inflammation in mice

scientific article

Effects of inhaled air pollution on markers of integrity, inflammation, and microbiota profiles of the intestines in Apolipoprotein E knockout mice

scientific article published on 14 November 2019

Effects of low sulfur fuel and a catalyzed particle trap on the composition and toxicity of diesel emissions

scientific article

Effects of simulated downwind coal combustion emissions on pre-existing allergic airway responses in mice ⬇️

scientific article published on 01 November 2011

Emission rates and comparative chemical composition from selected in-use diesel and gasoline-fueled vehicles

scientific article published on September 2004

Emissions from charbroiling and grilling of chicken and beef

scientific article published on February 2003

Engine exhaust particulate and gas phase contributions to vascular toxicity

scientific article

Engine-Operating Load Influences Diesel Exhaust Composition and Cardiopulmonary and Immune Responses ⬇️

scientific article published on April 25, 2011

Evaluation of inhaled carbon monoxide as an anti-inflammatory therapy in a nonhuman primate model of lung inflammation ⬇️

scientific article published on August 20, 2010

Evaluation of potential for toxicity from subacute inhalation of tire and road wear particles in rats ⬇️

scientific article published on November 1, 2012

Exposure to Traffic-Generated Air Pollution Promotes Alterations in the Integrity of the Brain Microvasculature and Inflammation in Female ApoE<sup>-/-</sup> mice

scientific article published on 26 December 2020

Exposure to traffic-generated air pollutants mediates alterations in brain microvascular integrity in wildtype mice on a high-fat diet

scientific article published on 23 October 2017

Exposure to vehicle emissions results in altered blood brain barrier permeability and expression of matrix metalloproteinases and tight junction proteins in mice

scientific article published on 17 December 2013

Fine Particle and Gaseous Emission Rates from Residential Wood Combustion

article

Formation of vascular S-nitrosothiols and plasma nitrates/nitrites following inhalation of diesel emissions

scientific article

Formulation development and in vivo evaluation of a new dry powder formulation of albuterol sulphate in beagle dogs

scientific article

Fresh gasoline emissions, not paved road dust, alter cardiac repolarization in ApoE-/- mice

scientific article published in January 2006

Gas-phase photolytic production of hydroxyl radicals in an ultraviolet purifier for air and surfaces

scientific article published on 14 September 2016

Gasoline exhaust emissions induce vascular remodeling pathways involved in atherosclerosis

scientific article published on 25 October 2006

Generation and Characterization of Hardwood Smoke Inhalation Exposure Atmospheres

journal article; published in Aerosol Science and Technology in 2006

Generation and characterization of four dilutions of diesel engine exhaust for a subchronic inhalation study

scientific article

Generation and characterization of gasoline engine exhaust inhalation exposure atmospheres

Genotoxicity of 1,3-butadiene and its epoxy intermediates.

scientific article published on August 2009

Hardwood smoke alters murine splenic T cell responses to mitogens following a 6-month whole body inhalation exposure

scientific article published in February 2005

Health effects of carbon-containing particulate matter: focus on sources and recent research program results

scientific article

Health effects of inhaled gasoline engine emissions

scientific article published on January 2007

Health effects of subchronic exposure to diesel-water emulsion emission

journal article published in 2005

Health effects of subchronic exposure to diesel-water-methanol emulsion emission

journal article published in 2006

Health effects of subchronic exposure to environmental levels of diesel exhaust

scientific article

Health effects of subchronic exposure to environmental levels of hardwood smoke

scientific article published on 01 July 2006

Health effects of subchronic exposure to low levels of wood smoke in rats.

scientific article published in January 2002

Health effects of subchronic inhalation exposure to gasoline engine exhaust

scientific article published in October 2008

Health effects of subchronic inhalation exposure to simulated downwind coal combustion emissions ⬇️

scientific article published on 01 May 2011

Identification of chemical components of combustion emissions that affect pro-atherosclerotic vascular responses in mice.

scientific article published on April 2012

Identification of urinary metabolites of orally administered N,N-dimethyl-p-toluidine in male F344 rats

scientific article published on 01 May 2007

Immunotoxicity and biodistribution analysis of arsenic trioxide in C57Bl/6 mice following a 2-week inhalation exposure

scientific article

Impact of prenatal polycyclic aromatic hydrocarbon exposure on behavior, cortical gene expression and DNA methylation of the Bdnf gene

scientific article published on March 2016

In vitro versus in vivo exposure to combustion emissions

scientific article published on July 2005

Increased susceptibility to RSV infection by exposure to inhaled diesel engine emissions

scientific article published in April 2003

Inflammation, mucous cell metaplasia, and Bcl-2 expression in response to inhaled lipopolysaccharide aerosol and effect of rolipram.

scientific article

Inflammatory and Vasoactive Effects of Serum Following Inhalation of Varied Complex Mixtures

scientific article

Inhalation administration of all-trans-retinoic acid for treatment of elastase-induced pulmonary emphysema in Fischer 344 rats

scientific article

Inhalation exposure systems for the development of rodent models of sulfur mustard-induced pulmonary injury

scientific article

Inhalation toxicity of brevetoxin 3 in rats exposed for 5 days

scientific article

Inhalation toxicity of brevetoxin 3 in rats exposed for twenty-two days

scientific article

Inhaled PYY(3-36) dry-powder formulation for appetite suppression

scientific article

Inhaled diesel emissions alter atherosclerotic plaque composition in ApoE(-/-) mice

scientific article

Innovations in methodologies for inhalation exposure and interpretations of in vivo toxicity ⬇️

abstract published in 2014

Iodinated NanoClusters as an inhaled computed tomography contrast agent for lung visualization

scientific article published on August 2010

Levofloxacin Cures Experimental Pneumonic Plague in African Green Monkeys ⬇️

scientific article published on February 8, 2011

Local and systemic tolerability of a 2'O-methoxyethyl antisense oligonucleotide targeting interleukin-4 receptor-α delivery by inhalation in mouse and monkey

scientific article published on 16 June 2014

Low-level subchronic exposure to wood smoke exacerbates inflammatory responses in allergic rats.

scientific article published on 14 September 2005

Lung toxicity of ambient particulate matter from southeastern U.S. sites with different contributing sources: relationships between composition and effects

scientific article

Measurement of plasma or urinary metabolites and Hprt mutant frequencies following inhalation exposure of mice and rats to 3-butene-1,2-diol

scientific article published on 12 February 2007

Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice

scientific article published on 14 June 2009

Medical nebulizer performance: effects of cascade impactor temperature.

scientific article

Metabolism and disposition of 2-hydroxy-4-methoxybenzophenone, a sunscreen ingredient, in Harlan Sprague Dawley rats and B6C3F1/N mice; a species and route comparison

scientific article published on 31 October 2019

Metabolomic changes in murine serum following inhalation exposure to gasoline and diesel engine emissions

scientific article published on 28 March 2016

Microglial priming through the lung-brain axis: the role of air pollution-induced circulating factors.

scientific article published on 10 February 2016

Mixed Vehicle Emissions Induces Angiotensin II and Cerebral Microvascular Angiotensin Receptor Expression in C57Bl/6 Mice and Promotes Alterations in Integrity in a Blood-Brain Barrier Coculture Model

scientific article published on 01 August 2019

Modulators of cigarette smoke-induced pulmonary emphysema in A/J mice

scientific article published on 12 May 2006

Molecular dosimetry of N2-hydroxymethyl-dG DNA adducts in rats exposed to formaldehyde ⬇️

scientific article

Mutagenicity and in vivo toxicity of combined particulate and semivolatile organic fractions of gasoline and diesel engine emissions

scientific article published on December 2002

NOS-2 Inhibition in Phosgene-Induced Acute Lung Injury

scientific article published on 13 April 2015

Nasal Deposition of HFA-Beclomethasone, Aqueous Fluticasone Propionate and Aqueous Mometasone Furoate in Allergic Rhinitis Patients

scientific article published on 11 February 2015

National Particle Component Toxicity (NPACT) initiative report on cardiovascular effects

scientific article

New methodology for quantifying polycyclic aromatic hydrocarbons (PAHs) using high-resolution aerosol mass spectrometry

journal article published in 2015

Nonparticulate components of diesel exhaust promote constriction in coronary arteries from ApoE-/- mice

scientific article

Oxidative stress, inflammation, and pulmonary function assessment in rats exposed to laboratory-generated pollutant mixtures

scientific article published in January 2008

Part 1. Assessment of carcinogenicity and biologic responses in rats after lifetime inhalation of new-technology diesel exhaust in the ACES bioassay.

scientific article published on January 2015

Polycyclic Aromatic Hydrocarbons Impair Function of β2-Adrenergic Receptors in Airway Epithelial and Smooth Muscle Cells ⬇️

scientific article published on May 26, 2011

Prenatal and postnatal polycyclic aromatic hydrocarbon exposure, airway hyperreactivity, and Beta-2 adrenergic receptor function in sensitized mouse offspring

scientific article published on 12 December 2013

Prenatal polycyclic aromatic hydrocarbon, adiposity, peroxisome proliferator-activated receptor (PPAR) γ methylation in offspring, grand-offspring mice.

scientific article

Pulmonary and Regional Deposition of Nebulized and Dry Powder Aerosols in Ferrets

scientific article published on 01 July 2019

Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes

scientific article (publication date: November 2007)

Radiation-induced impairment in lung lymphatic vasculature

scientific article

Regional particle size dependent deposition of inhaled aerosols in rats and mice ⬇️

scientific article published on December 7, 2011

Relationship between composition and toxicity of motor vehicle emission samples

scientific article

Respiratory Tract Deposition of HFA-Beclomethasone and HFA-Fluticasone in Asthmatic Patients

scientific article

Responses of differentiated primary human lung epithelial cells to exposure to diesel exhaust at an air-liquid interface

scientific article published in January 2007

Responses to subchronic inhalation of low concentrations of diesel exhaust and hardwood smoke measured in rat bronchoalveolar lavage fluid

scientific article published in November 2005

Safety assessment of nebulized xylitol in beagle dogs

scientific article published on 01 May 2012

Simulated downwind coal combustion emissions for laboratory inhalation exposure atmospheres ⬇️

scientific article published on 01 April 2012

Source Apportionment of Airborne Fine Particulate Matter in an Underground Mine ⬇️

scientific article published on April 1, 2003

Source-to-receptor pathways of anthropogenic PM2.5 in Detroit, Michigan: Comparison of two inhalation exposure studies

Surface area-dependence of gas-particle interactions influences pulmonary and neuroinflammatory outcomes.

scientific article published on December 2016

Syndecan-2 Attenuates Radiation-induced Pulmonary Fibrosis and Inhibits Fibroblast Activation by Regulating PI3K/Akt/ROCK Pathway via CD148.

scientific article published on 8 September 2017

Systemic immunotoxicity in AJ mice following 6-month whole body inhalation exposure to diesel exhaust

scientific article published in May 2004

TSC2 Deficiency Unmasks a Novel Necrosis Pathway That Is Suppressed by the RIP1/RIP3/MLKL Signaling Cascade

scientific article published on 18 October 2016

Temporal-spatial analysis of U.S.-Mexico border environmental fine and coarse PM air sample extract activity in human bronchial epithelial cells

scientific article (publication date: July 2009)

The National Environmental Respiratory Center (NERC) experiment in multi-pollutant air quality health research: II. Comparison of responses to diesel and gasoline engine exhausts, hardwood smoke and simulated downwind coal emissions.

scientific article published in September 2014

The National Environmental Respiratory Center (NERC) experiment in multi-pollutant air quality health research: IV. Vascular effects of repeated inhalation exposure to a mixture of five inorganic gases.

scientific article published in September 2014

The effects of subacute inhaled multi-walled carbon nanotube exposure on signaling pathways associated with cholesterol transport and inflammatory markers in the vasculature of wild-type mice

scholarly article by Griffith Davis et al published 15 October 2018 in Toxicology Letters

The effects of α-pinene versus toluene-derived secondary organic aerosol exposure on the expression of markers associated with vascular disease

scientific article published in May 2013

The in vivo efficacy and side effect pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long-acting β 2-adrenoceptor agonist in preclinical animal species

scientific article

The oxidized low-density lipoprotein receptor mediates vascular effects of inhaled vehicle emissions

scientific article

The pharmacokinetics of ketamine following intramuscular injection to F344 rats

scientific article published on 14 August 2018

The role of the lectin-like oxLDL receptor (LOX-1) in traffic-generated air pollution exposure-mediated alteration of the brain microvasculature in Apolipoprotein (Apo) E knockout mice.

scientific article published on 17 August 2017

Toward distinguishing woodsmoke and diesel exhaust in ambient particulate matter

scientific article

Toxicological assessment of diesel-methanol-water emulsion [Purinox (all weather) generation 2 fuel] exhaust emissions ⬇️

abstract published in 2004

Toxicological assessment of diesel-water emulsion [Purinox (summer fuel blend)] exhaust emissions ⬇️

abstract published in 2004

Use of Medical Cannabis to Treat Traumatic Brain Injury

scientific article published on 30 November 2020

Vehicular Particulate Matter (PM) Characteristics Impact Vascular Outcomes Following Inhalation

scientific article published on 13 August 2019

Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1-mediated pathways

scientific article

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