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List of works by Marc Lievens

A Phase IIa Controlled Human Malaria Infection and Immunogenicity Study of RTS,S/AS01E and RTS,S/AS01B Delayed Fractional Dose Regimens in Malaria-Naïve Adults

scientific article published on 20 July 2020

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

scientific article

A randomized trial assessing the safety and immunogenicity of AS01 and AS02 adjuvanted RTS,S malaria vaccine candidates in children in Gabon

scientific article

Ad35.CS.01-RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults

scientific article published on 6 July 2015

Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01E and Protection against P falciparum Clinical Malaria ⬇️

scientific article published on October 6, 2011

Correction: Randomized Controlled Trial of RTS,S/AS02D and RTS,S/AS01E Malaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children.

scientific article

Correction: Safety of the Malaria Vaccine Candidate, RTS,S/AS01 in 5 to 17 Month Old Kenyan and Tanzanian Children

article by John Lusingu et al published 28 December 2010 in PLOS ONE

Correction: Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children.

scientific article

Design of a phase III multicenter trial to evaluate the efficacy of the RTS,S/AS01 malaria vaccine in children across diverse transmission settings in Africa

scientific article

Development and technical and clinical validation of a quantitative enzyme-linked immunosorbent assay for the detection of human antibodies to hepatitis B surface antigen in recipients of recombinant hepatitis B virus vaccine

scientific article published on 24 June 2009

Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial

scientific article published on December 2005

Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children ⬇️

scientific article

Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial

scientific article published on 13 January 2011

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

scientific article

Environmental modifiers of RTS,S/AS01 malaria vaccine efficacy in Lilongwe, Malawi

scientific article published on 12 June 2020

Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area.

scientific article

Evaluation of the immune response to RTS,S/AS01 and RTS,S/AS02 adjuvanted vaccines: randomized, double-blind study in malaria-naïve adults

scientific article published on January 2014

Evaluation of the safety and immunogenicity of the RTS,S/AS01 E malaria candidate vaccine when integrated in the expanded program of immunization

scientific article published on October 2010

Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial

scientific article published on 26 March 2007

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

scientific article

Five-year safety and immunogenicity of GlaxoSmithKline's candidate malaria vaccine RTS,S/AS02 following administration to semi-immune adult men living in a malaria-endemic region of The Gambia

scientific article published on 22 April 2009

Four year immunogenicity of the RTS,S/AS02(A) malaria vaccine in Mozambican children during a phase IIb trial

scientific article published on 7 April 2011

Four-year efficacy of RTS,S/AS01E and its interaction with malaria exposure

scientific article published on March 2013

Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

scientific article

Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine

scientific article published on 21 October 2015

Hepatitis A vaccine: indirect evidence of immune memory 12 years after the primary course

scientific article published in February 2004

Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections

scientific article published on 11 April 2018

Immune response to the hepatitis B antigen in the RTS,S/AS01 malaria vaccine, and co-administration with pneumococcal conjugate and rotavirus vaccines in African children: A randomized controlled trial

scientific article published on 13 April 2018

Immunogenicity and safety of an adjuvanted hepatitis B vaccine in pre-hemodialysis and hemodialysis patients

scientific article

Immunogenicity and safety of the RTS,S/AS01 malaria vaccine co-administered with measles, rubella and yellow fever vaccines in Ghanaian children: A phase IIIb, multi-center, non-inferiority, randomized, open, controlled trial

scientific article published on 17 March 2020

Immunogenicity and safety of the candidate RTS,S/AS01 vaccine in young Nigerian children: a randomized, double-blind, lot-to-lot consistency trial

scientific article published on 28 July 2014

Immunogenicity of Twinrix in older adults: a critical analysis

scientific article

Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial

scientific article

Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

scientific article (publication date: 11 April 2011)

Insights into long-lasting protection induced by RTS,S/AS02A malaria vaccine: further results from a phase IIb trial in Mozambican children

scientific article

Long-term immunogenicity and immune memory response to the hepatitis B antigen in the RTS,S/AS01E malaria vaccine in African children: a randomized trial

scientific article published on 17 January 2020

Long-term incidence of severe malaria following RTS,S/AS01 vaccination in children and infants in Africa: an open-label 3-year extension study of a phase 3 randomised controlled trial

scientific article published on 09 July 2019

Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children

scientific article published on August 2009

Malaria treatment with atovaquone-proguanil in malaria-immune adults: implications for malaria intervention trials and for pre-exposure prophylaxis of malaria

scientific article published on 11 February 2008

Pooled analysis of safety data from pediatric Phase II RTS,S/AS malaria candidate vaccine trials ⬇️

scientific article published on December 1, 2011

RTS,S malaria vaccine efficacy and immunogenicity during Plasmodium falciparum challenge is associated with HLA genotype

scientific article published on 10 February 2018

RTS,S/AS01 Malaria Vaccine Efficacy is Not Modified by Seasonal Precipitation: Results from a Phase 3 Randomized Controlled Trial in Malawi

scientific article published on 3 August 2017

RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection

scientific article published on 19 May 2006

Randomized controlled trial of RTS,S/AS02D and RTS,S/AS01E malaria candidate vaccines given according to different schedules in Ghanaian children

scientific article published on 2 October 2009

Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02D malaria vaccine in infants living in a malaria-endemic region ⬇️

scientific article published on January 8, 2013

Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection

scientific article

Response to "Poor control vaccines in two randomised trials of malaria vaccine?".

scientific article published on 30 May 2009

Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP.

scientific article published on 15 June 2016

Safety and Immunogenicity of Seven Dosing Regimens of the Candidate RTS,S/AS01E Malaria Vaccine Integrated within an Expanded Program on Immunization Regimen: A Phase II, Single-Center, Open, Controlled Trial in Infants in Malawi

scientific article published on 9 February 2018

Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP

scientific article published on 09 October 2018

Safety and efficacy of the RTS, S/AS01 E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial

scientific article

Safety and immunogenicity of RTS,S/AS01 malaria vaccine in infants and children with WHO stage 1 or 2 HIV disease: a randomised, double-blind, controlled trial

scientific article published on 6 July 2016

Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants

scientific article

Safety and immunogenicity of the RTS,S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in sub-Saharan Africa

scientific article published on 07 November 2019

Safety and immunogenicity profile of an experimental hepatitis B vaccine adjuvanted with AS04

scientific article published on 01 December 2004

Safety of the RTS,S/AS02A malaria vaccine in Mozambican children during a Phase IIb trial

scientific article

Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

scientific article

Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children

scientific article (publication date: 29 November 2010)

Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa

scientific article published on 23 April 2019

Safety, immunogenicity and duration of protection of the RTS,S/AS02(D) malaria vaccine: one year follow-up of a randomized controlled phase I/IIb trial

scientific article (publication date: 4 November 2010)

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

scientific article (publication date: 2011)

Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children

scientific article published on June 2016

Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS, S/AS01 malaria vaccine in African children

scientific article

The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01E on protective efficacy and anti-circumsporozoite protein antibody avidity in African infants

scientific article

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