List of works by Leslie M. Shaw

2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

scientific article

3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects

scientific article

A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank

scientific article published on 24 August 2013

APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern

scientific article

Active Cigarette Smoking in Cognitively-Normal Elders and Probable Alzheimer's Disease is Associated with Elevated Cerebrospinal Fluid Oxidative Stress Biomarkers

scientific article published on 25 July 2016

Alzheimer risk genes modulate the relationship between plasma apoE and cortical PiB binding

scientific article published on 15 October 2015

Alzheimer's disease biomarkers: walk with deliberate haste, don't run blithely on?

scientific article

Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects

scientific article

Alzheimer's disease neuroimaging initiative: a one-year follow up study using tensor-based morphometry correlating degenerative rates, biomarkers and cognition

scientific article published on April 2009

An Alzheimer's Disease-Derived Biomarker Signature Identifies Parkinson's Disease Patients with Dementia

scientific article

Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration

scientific article

ApoE4 effects on automated diagnostic classifiers for mild cognitive impairment and Alzheimer's disease

scientific article published on 04 January 2014

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer's disease

scientific article

Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression

scientific article published on 2 November 2015

Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease

scientific article

Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease

scientific article published on 23 August 2013

Association of plasma and cortical amyloid beta is modulated by APOE ε4 status

scientific article published on 26 March 2013

Biomarker discovery for Alzheimer's disease, frontotemporal lobar degeneration, and Parkinson's disease

scientific article

Biomarkers in frontotemporal lobar degenerations--progress and challenges

scientific article

Biomarkers of neurodegeneration for diagnosis and monitoring therapeutics

scientific article published on 9 March 2007

Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease

scientific article published on 17 June 2011

Brain amyloidosis ascertainment from cognitive, imaging, and peripheral blood protein measures

scientific article

Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease

scientific article

CSF Apo-E levels associate with cognitive decline and MRI changes

scientific article published on 03 January 2014

CSF beta-amyloid 1-42 - what are we measuring in Alzheimer's disease?

scientific article

CSF biomarker and PIB-PET-derived beta-amyloid signature predicts metabolic, gray matter, and cognitive changes in nondemented subjects

scientific article

CSF biomarker variability in the Alzheimer's Association quality control program

scientific article published on May 2013

CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study

scientific article published on 28 March 2016

CSF biomarkers cutoffs: the importance of coincident neuropathological diseases

scientific article published on 22 April 2012

CSF α-synuclein improves diagnostic and prognostic performance of CSF tau and Aβ in Alzheimer's disease

scientific article published on 29 June 2013

Cardiovascular risk factors, cortisol, and amyloid-β deposition in Alzheimer's Disease Neuroimaging Initiative

scientific article published on November 2012

Cerebrospinal fluid abnormalities and rate of decline in everyday function across the dementia spectrum: normal aging, mild cognitive impairment, and Alzheimer disease

scientific article

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

scientific article published on April 2009

Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer's disease

scientific article

Cerebrospinal fluid profiles and prospective course and outcome in patients with amnestic mild cognitive impairment

scientific article

Characterizing Alzheimer's disease using a hypometabolic convergence index

scientific article

Clinical Core of the Alzheimer's Disease Neuroimaging Initiative: progress and plans

scientific article

Clinical and multimodal biomarker correlates of ADNI neuropathological findings

scientific article published on 09 October 2013

Cognitive and functional resilience despite molecular evidence of Alzheimer's disease pathology

scientific article published on 2 November 2012

Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral sclerosis

scientific article published on 31 October 2012

Cognitive reserve and Alzheimer's disease biomarkers are independent determinants of cognition

scientific article

Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β-amyloid

scientific article published on December 2013

Comparison of analytical platforms for cerebrospinal fluid measures of β-amyloid 1-42, total tau, and p-tau181 for identifying Alzheimer disease amyloid plaque pathology

scientific article

Comparison of cerebrospinal fluid levels of tau and Aβ 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms

scientific article

Comparison of xMAP and ELISA assays for detecting cerebrospinal fluid biomarkers of Alzheimer's disease

scientific article published on January 2012

Design of comprehensive Alzheimer's disease centers to address unmet national needs

scientific article

Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease

scientific article

Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people

scientific article

Diagnostic accuracy of CSF Ab42 and florbetapir PET for Alzheimer's disease

scientific article

Effect of apolipoprotein E on biomarkers of amyloid load and neuronal pathology in Alzheimer disease

scientific article

Effects of cerebrospinal fluid proteins on brain atrophy rates in cognitively healthy older adults

scientific article published on October 2013

Effects of traumatic brain injury and posttraumatic stress disorder on Alzheimer's disease in veterans, using the Alzheimer's Disease Neuroimaging Initiative

scientific article

Emerging β-amyloid pathology and accelerated cortical atrophy

scientific article published on June 2014

Evidence for ordering of Alzheimer disease biomarkers

scientific article

Factors affecting Aβ plasma levels and their utility as biomarkers in ADNI

scientific article published on 30 July 2011

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

scientific article

Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers

scientific article published on 28 February 2017

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism

scientific article

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

scientific article

History of cigarette smoking in cognitively-normal elders is associated with elevated cerebrospinal fluid biomarkers of oxidative stress

scientific article

Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study

scientific article published in September 2015

Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014

scientific article

Improved protocol for measurement of plasma β-amyloid in longitudinal evaluation of Alzheimer's Disease Neuroimaging Initiative study patients

scientific article published on July 2012

Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease

scientific article

Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel

scientific article

Integration and relative value of biomarkers for prediction of MCI to AD progression: spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers

scientific article

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease

scientific article

Lack of shunt response in suspected idiopathic normal pressure hydrocephalus with Alzheimer disease pathology

scientific article

Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI

scientific article published on 29 June 2013

Longitudinal change of biomarkers in cognitive decline

scientific article published on 13 June 2011

Longitudinal plasma amyloid beta as a biomarker of Alzheimer's disease

scientific article published on 22 February 2012

Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairment

scientific article

Low plasma ApoE levels are associated with smaller hippocampal size in the Alzheimer's disease neuroimaging initiative cohort

scientific article

Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential

scientific article

Mapping correlations between ventricular expansion and CSF amyloid and tau biomarkers in 240 subjects with Alzheimer's disease, mild cognitive impairment and elderly controls

scientific article published on 21 February 2009

Memory, executive, and multidomain subtle cognitive impairment: clinical and biomarker findings

scientific article published on 17 June 2015

Multimodal imaging evidence of pathology-mediated disease distribution in corticobasal syndrome

scientific article published on 19 August 2016

Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition

scientific article

Nonlinear Association Between Cerebrospinal Fluid and Florbetapir F-18 β-Amyloid Measures Across the Spectrum of Alzheimer Disease

scientific article published on May 2015

Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment

scientific article

Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus

scientific article published on 23 March 2012

Plasma Tau Association with Brain Atrophy in Mild Cognitive Impairment and Alzheimer's Disease

scientific article published on 25 May 2017

Plasma amyloid beta measurements - a desired but elusive Alzheimer's disease biomarker

scientific article published on 08 March 2013

Plasma biomarkers associated with the apolipoprotein E genotype and Alzheimer disease

scientific article published on October 2012

Plasma epidermal growth factor levels predict cognitive decline in Parkinson disease

scientific article

Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease

scientific article

Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging

scientific article published on 13 April 2016

Plasma tau in Alzheimer disease

scientific article published on 30 September 2016

Prediction of MCI to AD conversion, via MRI, CSF biomarkers, and pattern classification

scientific article

Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance

scientific article published on 14 December 2010

Qualification of a surrogate matrix-based absolute quantification method for amyloid-β₄₂ in human cerebrospinal fluid using 2D UPLC-tandem mass spectrometry

scientific article

Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI.

scientific article

Relations between brain tissue loss, CSF biomarkers, and the ApoE genetic profile: a longitudinal MRI study

scientific article

Relationship between CSF biomarkers of Alzheimer's disease and rates of regional cortical thinning in ADNI data

scientific article

Relationship between plasma analytes and SPARE-AD defined brain atrophy patterns in ADNI

scientific article

Role of cerebrospinal fluid biomarkers in clinical trials for Alzheimer's disease modifying therapies

scientific article

Shapes of the trajectories of 5 major biomarkers of Alzheimer disease

scientific article published on July 2012

Simultaneous HPLC-MS-MS quantification of 8-iso-PGF(2alpha) and 8,12-iso-iPF(2alpha) in CSF and brain tissue samples with on-line cleanup

scientific article

Simultaneous analysis of cerebrospinal fluid biomarkers using microsphere-based xMAP multiplex technology for early detection of Alzheimer's disease

scientific article published on 06 April 2012

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

scientific article published on July 2011

The Alzheimer's Disease Neuroimaging Initiative 2 Biomarker Core: A review of progress and plans

scientific article published on July 2015

The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement

scientific article

The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.

scientific article

The Alzheimer's disease neuroimaging initiative: progress report and future plans

scientific article (publication date: May 2010)

The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI).

scientific article published on April 2013

The transitional association between β-amyloid pathology and regional brain atrophy

scientific article published on 9 December 2014

Total and phosphorylated tau protein as biological markers of Alzheimer's disease

scientific article

Transforming cerebrospinal fluid Aβ42 measures into calculated Pittsburgh Compound B units of brain Aβ amyloid

scientific article

Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects

scientific article

VENTRICULAR MAPS IN 804 SUBJECTS CORRELATE WITH COGNITIVE DECLINE, CSF PATHOLOGY, AND IMMINENT ALZHEIMER'S DISEASE

scientific article

Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects

scientific article published on September 2015

Ventricular maps in 804 ADNI subjects: correlations with CSF biomarkers and clinical decline

scientific article

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