List of works - Liam Sebag-Montefiore

A role for thioredoxin-interacting protein (Txnip) in cellular creatine homeostasis

scientific article published on 28 May 2013

Abnormal cardiac morphology, function and energy metabolism in the dystrophic mdx mouse: an MRI and MRS study

scientific article

Cardiac dysfunction and peri-weaning mortality in malonyl-coenzyme A decarboxylase (MCD) knockout mice as a consequence of restricting substrate plasticity

scientific article

Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background

scientific article

Changes in creatine transporter function during cardiac maturation in the rat.

scientific article

Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age

scientific article

Creatine uptake in mouse hearts with genetically altered creatine levels

scientific article published on 10 June 2008

High-energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymes.

scientific article

In vivo cardiac 1H-MRS in the mouse

scientific article

Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice

scientific article

Mice over-expressing the myocardial creatine transporter develop progressive heart failure and show decreased glycolytic capacity

scientific article

Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction

scientific article

Modulation of myocardial creatine transporter levels and the effects of gene regulation and post-translational modification on its function

doctoral thesis by Liam M. Sebag-Montefiore

On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury.

scientific article published on 21 April 2016

Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome

scientific article

Reduced inotropic reserve and increased susceptibility to cardiac ischemia/reperfusion injury in phosphocreatine-deficient guanidinoacetate-N-methyltransferase-knockout mice

scientific article published on 9 May 2005

Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart.

scientific article

Serial high resolution 3D–MRI after aortic banding in mice: band internalization is a source of variability in the hypertrophic response

scientific article published on 01 September 2005

Supranormal myocardial creatine and phosphocreatine concentrations lead to cardiac hypertrophy and heart failure: insights from creatine transporter-overexpressing transgenic mice

scientific article published on November 2005

The creatine kinase energy transport system in the failing mouse heart

scientific article published on 27 March 2007

List of works by Liam Sebag-Montefiore

A role for thioredoxin-interacting protein (Txnip) in cellular creatine homeostasis

Abnormal cardiac morphology, function and energy metabolism in the dystrophic mdx mouse: an MRI and MRS study

Cardiac dysfunction and peri-weaning mortality in malonyl-coenzyme A decarboxylase (MCD) knockout mice as a consequence of restricting substrate plasticity

Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background

Changes in creatine transporter function during cardiac maturation in the rat.

Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age

Creatine uptake in mouse hearts with genetically altered creatine levels

High-energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymes.

In vivo cardiac 1H-MRS in the mouse

Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice

Mice over-expressing the myocardial creatine transporter develop progressive heart failure and show decreased glycolytic capacity

Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction

Modulation of myocardial creatine transporter levels and the effects of gene regulation and post-translational modification on its function

On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury.

Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome

Reduced inotropic reserve and increased susceptibility to cardiac ischemia/reperfusion injury in phosphocreatine-deficient guanidinoacetate-N-methyltransferase-knockout mice

Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart.

Serial high resolution 3D–MRI after aortic banding in mice: band internalization is a source of variability in the hypertrophic response

Supranormal myocardial creatine and phosphocreatine concentrations lead to cardiac hypertrophy and heart failure: insights from creatine transporter-overexpressing transgenic mice

The creatine kinase energy transport system in the failing mouse heart