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List of works by David Sidransky

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment

scientific article published on 30 May 2016

A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non-Small Cell Lung Cancer and Serum DNA.

scientific article published on 29 August 2017

A Pilot Clinical Study of Treatment Guided by Personalized Tumorgrafts in Patients with Advanced Cancer ⬇️

scientific article published on June 14, 2011

A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma

scientific article published on 31 October 2016

A novel response element confers p63- and p73-specific activation of the WNT4 promoter

scientific article

A p53-type response element in the GDF15 promoter confers high specificity for p53 activation

scientific article published on 25 January 2007

A promoter methylation pattern in the N-methyl-D-aspartate receptor 2B gene predicts poor prognosis in esophageal squamous cell carcinoma

scientific article published in November 2007

A quantitative promoter methylation profile of prostate cancer

scientific article

A randomized phase II efficacy and correlative studies of cetuximab with or without sorafenib in recurrent and/or metastatic head and neck squamous cell carcinoma.

scientific article published on 13 January 2015

A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma

scientific article

A transcriptional progression model for head and neck cancer.

scientific article published in August 2003

A tumor-suppressive role for trypsin in human cancer progression ⬇️

scientific article published on October 15, 2003

AIM1 promoter hypermethylation as a predictor of decreased risk of recurrence following radical prostatectomy

scientific article

ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage

scientific article

Aberrant promoter methylation of multiple genes during pathogenesis of bladder cancer.

scientific article published on October 2008

Absence of ST7 gene alterations in human cancer

scientific article (publication date: September 2002)

Absence of V599E BRAF mutations in desmoplastic melanomas.

scientific article published in February 2005

Abstract 2482: Key tumor suppressor genes inactivated by promoter methylation and somatic mutations in head and neck cancer

article

Abstract 3640: Validation of qBiomarker as an accurate and efficient mutation detection method in a comprehensive analysis of patient-derived tumor xenografts

Abstract 527: Analysis of the interaction between microRNAs and Notch pathway members in HNSCC (head and neck squamous cell carcinoma)

Abstract B1-62: Bumphunting analysis identifies PAX5 promoter methylation and p53 somatic mutations in genomic instability pathways linked to very poor survival in head and neck cancer

Activation of the NOTCH pathway in head and neck cancer ⬇️

scientific article published on 18 December 2013

Adenoid cystic carcinoma: emerging role of translocations and gene fusions

scientific article published on 14 August 2016

Adenylate Kinase 3 Sensitizes Cells to Cigarette Smoke Condensate Vapor Induced Cisplatin Resistance ⬇️

scientific article published on June 15, 2011

Advancing toward a molecular characterization of polymorphous low grade adenocarcinoma.

scientific article published on 19 September 2017

Alteration of Cellular and Humoral Immunity by Mutant p53 Protein and Processed Mutant Peptide in Head and Neck Cancer

scientific article published on 01 December 2007

Alterations of GPI transamidase subunits in head and neck squamous carcinoma

scientific article

Altered sumoylation of p63alpha contributes to the split-hand/foot malformation phenotype

scientific journal article

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer

scientific article

An accelerated pathway for targeted cancer therapies.

scientific article

An epigenetic marker panel for detection of lung cancer using cell-free serum DNA.

scientific article

An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine

scientific article

An integrated genome-wide approach to discover deregulated microRNAs in non-small cell lung cancer: Clinical significance of miR-23b-3p deregulation.

scientific article

An oligonucleotide microarray for high-throughput sequencing of the mitochondrial genome

scientific article published on September 2006

Antiviral effect of ranpirnase against Ebola virus

scientific article published on 24 June 2016

Aquaporin 1 is overexpressed in lung cancer and stimulates NIH-3T3 cell proliferation and anchorage-independent growth

scientific article

Aquaporin expression in human lymphocytes and dendritic cells

scientific article published on March 2004

Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.

scientific article published on 25 August 2011

Assessment of gene promoter hypermethylation for detection of cervical neoplasia.

scientific article

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

scientific article published on April 2013

Association between lifestyle factors and CpG island methylation in a cancer-free population.

scientific article

Association of promoter methylation of VGF and PGP9.5 with ovarian cancer progression.

scientific article

BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer

scientific article published on 10 May 2011

BRAF Mutation in Papillary Thyroid Carcinoma ⬇️

scientific article published on April 16, 2003

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer

scientific article

BRAF mutations in anaplastic thyroid carcinoma: implications for tumor origin, diagnosis and treatment

scientific article

Biallelic inactivation of the RIZ1 gene in human gastric cancer ⬇️

scientific article (publication date: 9 October 2003)

Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy.

scientific article published on 21 February 2018

Biomarkers for lung cancer screening and detection

scientific article published on 22 October 2020

CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer

scientific article

Cancer epigenetics: above and beyond

scientific article published in May 2011

Cellular FLICE-like Inhibitory Protein Long Form (c-FLIPL) Overexpression is Related to Cervical Cancer Progression ⬇️

scientific article published on May 1, 2013

Cellular transformation by cigarette smoke extract involves alteration of glycolysis and mitochondrial function in esophageal epithelial cells

scientific article

Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression

scientific article published on 29 September 2009

Characterization of a human homologue of proteolysis-inducing factor and its role in cancer cachexia

scientific article

Characterization of the Methylation Patterns in Human Papillomavirus Type 16 Viral DNA in Head and Neck Cancers ⬇️

scientific article published on February 1, 2011

Chemo brain or tumor brain - that is the question: the presence of extracranial tumors profoundly affects molecular processes in the prefrontal cortex of TumorGraft mice

scientific article

Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma

scientific article published on 22 March 2020

Chronic Cigarette Smoke Mediated Global Changes in Lung Mucoepidermoid Cells: A Phosphoproteomic Analysis

scientific article

Chronic Exposure to Chewing Tobacco Induces Metabolic Reprogramming and Cancer Stem Cell-Like Properties in Esophageal Epithelial Cells

scientific article published on 21 August 2019

Chronic exposure to chewing tobacco selects for overexpression of stearoyl-CoA desaturase in normal oral keratinocytes.

scientific article published on 21 September 2015

Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells

scientific article published on 16 August 2016

Chronic shisha exposure alters phosphoproteome of oral keratinocytes

scientific article published on 19 July 2019

Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes.

scientific article

Cigarette smoke induces methylation of the tumor suppressor gene NISCH

scientific article published on 15 March 2013

Cigarette smoke induces mitochondrial metabolic reprogramming in lung cells

scientific article

Cigarette smoke induces promoter methylation of single-stranded DNA-binding protein 2 in human esophageal squamous cell carcinoma

scientific article published on May 2011

Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features

scientific article

Clinical Correlates of Promoter Hypermethylation of Four Target Genes in Head and Neck Cancer: A Cooperative Group Correlative Study ⬇️

scientific article published on February 26, 2013

Clinical and public health research using methylated DNA immunoprecipitation (MeDIP): a comparison of commercially available kits to examine differential DNA methylation across the genome

scientific article published in January 2012

Clusterin is a gene-specific target of microRNA-21 in head and neck squamous cell carcinoma

scientific article published on 10 December 2013

Cold atmospheric plasma treatment selectively targets head and neck squamous cell carcinoma cells.

scientific article

Colorimetric approach to high-throughput mutation analysis

scientific article published on 01 April 2005

Common pathway signature in lung and liver fibrosis

scientific article

Comparative mutational landscape analysis of patient-derived tumour xenografts

scientific article published on 24 January 2017

Correction: Association of Promoter Methylation of and with Ovarian Cancer Progression

article published in 2013

Correction: Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression

scientific article published on 29 October 2013

Correction: Expression of Aquaporin 5 (AQP5) Promotes Tumor Invasion in Human Non Small Cell Lung Cancer.

scientific article

Correction: OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation

scientific article published on 12 September 2008

Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer

scientific article

Corrigendum: A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma.

scientific article published on 26 June 2017

Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers

scientific article

DCC promoter hypermethylation in esophageal squamous cell carcinoma.

scientific article published on June 2008

DNA methylation markers in colorectal cancer

scientific article published on March 2010

Death-associated protein kinase promoter hypermethylation in normal human lymphocytes.

scientific article

Decreased mitochondrial DNA content in posttreatment salivary rinses from head and neck cancer patients

scientific article published in March 2006

Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma

scientific article

DeltaNp63 induces beta-catenin nuclear accumulation and signaling

scientific article published on 01 May 2002

DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development ⬇️

scientific article published on May 15, 2003

DeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation

scientific article

DeltaNp63alpha levels correlate with clinical tumor response to cisplatin

scientific article published in October 2005

DeltaNp63alpha overexpression induces downregulation of Sirt1 and an accelerated aging phenotype in the mouse

scientific article

DeltaNp63alpha up-regulates the Hsp70 gene in human cancer

scientific article

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

scientific article

Detecting cervical cancer by quantitative promoter hypermethylation assay on cervical scrapings: a feasibility study.

scientific article

Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma

scientific article published on 01 January 2002

Detection of BRAF mutation on fine needle aspiration biopsy specimens: a new diagnostic tool for papillary thyroid cancer

scientific article published in June 2004

Detection of LOH and mitochondrial DNA alterations in ductal lavage and nipple aspirate fluids from hngh-risk patients

scientific article published in March 2004

Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer.

scientific article published on 14 August 2006

Detection of methylated CDO1 in plasma of colorectal cancer; a PCR study

scientific article

Detection of mitochondrial deoxyribonucleic acid alterations in urine from urothelial cell carcinoma patients

scientific article published on 30 August 2011

Detection of promoter hypermethylation in salivary rinses as a biomarker for head and neck squamous cell carcinoma surveillance

scientific article published on 31 May 2011

Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer

scientific article published on April 2004

Detection of serum deoxyribonucleic acid methylation markers: a novel diagnostic tool for thyroid cancer.

scientific article

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

scientific article

Differential DNA hypermethylation of critical genes mediates the stage-specific tobacco smoke-induced neoplastic progression of lung cancer

scientific article published in April 2005

Differential promoter methylation of kinesin family member 1a in plasma is associated with breast cancer and DNA repair capacity

scientific article

Differential recognition of response elements determines target gene specificity for p53 and p63

scientific article

Dose-dependent activation of putative oncogene SBSN by BORIS

scientific article (publication date: 2012)

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer

scientific article

Dysregulation of splicing proteins in head and neck squamous cell carcinoma.

scientific article published on 6 February 2016

Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies

scientific article

Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis.

scientific article published on March 2004

Efficacy of weekly docetaxel and bevacizumab in mesenchymal chondrosarcoma: a new theranostic method combining xenografted biopsies with a mathematical model

scientific article

Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations

scholarly article

Elevated AKAP12 in paclitaxel-resistant serous ovarian cancer cells is prognostic and predictive of poor survival in patients

scientific article

Emerging molecular markers of cancer.

scientific article

Endothelin receptor type B gene promoter hypermethylation in salivary rinses is independently associated with risk of oral cavity cancer and premalignancy.

scientific article

Epigenetic Silencing of HOPX Promotes Cancer Progression in Colorectal Cancer ⬇️

scientific article published on July 1, 2012

Epigenetic heterogeneity of high-grade prostatic intraepithelial neoplasia: clues for clonal progression in prostate carcinogenesis.

scientific article

Epigenetic inactivation of RASSF1A in head and neck cancer ⬇️

scientific article published on September 1, 2003

Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine.

scientific article

Epigenetic silencing of S100A2 in bladder and head and neck cancers

scientific article published on 16 March 2015

Epigenetic silencing of human T (brachyury homologue) gene in non-small-cell lung cancer.

scientific article published on 31 October 2007

Epigenomics-Based Diagnostics

scientific article published on 14 May 2010

Epstein-Barr virus in head and neck cancer assessed by quantitative polymerase chain reaction

scientific article

Erratum: Corrigendum: CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer

article

Establishment and characterization of a platinum- and paclitaxel-resistant high grade serous ovarian carcinoma cell line

scientific article published on March 2017

Evaluation of MYB promoter methylation in salivary adenoid cystic carcinoma ⬇️

scientific article published on February 15, 2011

Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma.

scientific article published on January 2008

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

scientific article (publication date: 26 August 2011)

Exon 15 BRAF mutations are uncommon in melanomas arising in nonsun-exposed sites

scientific article

Expression of GULP1 in bronchial epithelium is associated with the progression of emphysema in chronic obstructive pulmonary disease.

scientific article published on 17 February 2017

Expression of aquaporin 5 (AQP5) promotes tumor invasion in human non small cell lung cancer

scientific article

Expression status and prognostic significance of mammalian target of rapamycin pathway members in urothelial carcinoma of urinary bladder after cystectomy ⬇️

scientific article published on October 11, 2010

Feasibility of quantitative PCR-based saliva rinse screening of HPV for head and neck cancer.

scientific article

Fine mapping of chromosome 3 in uveal melanoma: identification of a minimal region of deletion on chromosomal arm 3p25.1-p25.2.

scientific article published in December 2003

First Person: David Sidransky, MD: Clinician-Scientist Transforms Cancer Early Detection

scientific article published on 01 August 2018

Fluorescence visualization in oral neoplasia: shedding light on an old problem

scientific article published on 01 November 2006

Following mitochondrial footprints through a long mucosal path to lung cancer

scientific article

Forced cytochrome B gene mutation expression induces mitochondrial proliferation and prevents apoptosis in human uroepithelial SV-HUC-1 cells.

scientific article

Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck

scientific article

Frequent 14-3-3 sigma promoter methylation in benign and malignant prostate lesions

scientific article

Functional characterization of alternatively spliced GSN in head and neck squamous cell carcinoma

scientific article published on 26 July 2018

GSTP1 promoter methylation is associated with recurrence in early stage prostate cancer

scientific article

Gene expression alterations over large chromosomal regions in cancers include multiple genes unrelated to malignant progression

scholarly article

Gene promoter hypermethylation in tumors and lymph nodes of stage I lung cancer patients

scientific article published in April 2003

Genetic and epigenetic analysis of erbB signaling pathway genes in lung cancer ⬇️

scientific article published on December 1, 2010

Genetic and epigenetic screening for gene alterations of the chromatin-remodeling factor, SMARCA4/BRG1, in lung tumors.

scientific article published on October 2004

Genome-wide and gene-specific epigenomic platforms for hepatocellular carcinoma biomarker development trials

scientific article

Genome-wide genetic characterization of bladder cancer: a comparison of high-density single-nucleotide polymorphism arrays and PCR-based microsatellite analysis ⬇️

scientific article published on 01 May 2003

Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma ⬇️

scientific article published on February 22, 2013

Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population

scientific article

Genome-wide promoter analysis uncovers portions of the cancer methylome.

scientific article

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.

scientific article

Germline Translocation t(5;20)(p15;q11) and Familial Transitional Cell Carcinoma

Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds

scientific article published on 16 August 2010

Global and gene-specific DNA methylation pattern discriminates cholecystitis from gallbladder cancer patients in Chile.

scientific article

Growth of Malignant Non-CNS Tumors Alters Brain Metabolome

scientific article published on 20 February 2018

Growth of Triple Negative and Progesterone Positive Breast Cancer Causes Oxidative Stress and Down-Regulates Neuroprotective Transcription Factor NPAS4 and NPAS4-Regulated Genes in Hippocampal Tissues of TumorGraft Mice-an Aging Connection

scientific article published on 5 March 2018

Growth of malignant extracranial tumors alters microRNAome in the prefrontal cortex of TumorGraft mice

scientific article published on 3 August 2017

HIST1H2BB and MAGI2 methylation and somatic mutations as precision medicine biomarkers for diagnosis and prognosis of high-grade serous ovarian cancer

scientific article published on 24 June 2020

HOP/OB1/NECC1 promoter DNA is frequently hypermethylated and involved in tumorigenic ability in esophageal squamous cell carcinoma

scientific article published on January 2008

Habitual risk factors for head and neck cancer

scientific article

Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO.

scientific article published on 2 November 2005

High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients.

scientific article published in October 2007

High-performance detection of somatic D-loop mutation in urothelial cell carcinoma patients by polymorphism ratio sequencing

scientific article published on 31 March 2016

High-resolution microbiome profiling uncovers Fusobacterium nucleatum, Lactobacillus gasseri/johnsonii, and Lactobacillus vaginalis associated to oral and oropharyngeal cancer in saliva from HPV positive and HPV negative patients treated with surger

scientific article published on 7 September 2017

High-throughput molecular analysis of urine sediment for the detection of bladder cancer by high-density single-nucleotide polymorphism array ⬇️

scientific article published on September 15, 2003

Human AQP5 plays a role in the progression of chronic myelogenous leukemia (CML).

scientific article

Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer

scientific article published on 22 September 2006

Hypermethylation of Genes Detected in Urine from Ghanaian Adults with Bladder Pathology Associated with Schistosoma haematobium Infection

scientific article

Hypermethylation of MCAM gene is associated with advanced tumor stage in prostate cancer.

scientific article published on March 2008

Hypermethylation of the Pendred syndrome gene SLC26A4 is an early event in thyroid tumorigenesis ⬇️

scientific article published on May 1, 2003

I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma

scientific article

INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program.

scientific article published on 14 November 2017

Identification of guanine nucleotide-binding protein γ-7 as an epigenetically silenced gene in head and neck cancer by gene expression profiling ⬇️

scientific article published on 06 February 2013

Identification of head and neck squamous cell carcinoma biomarker candidates through proteomic analysis of cancer cell secretome.

scientific article published on 7 May 2013

Identification of hypermethylated genes associated with cisplatin resistance in human cancers

scientific article published on 9 March 2010

Identification of mtDNA mutations in human cancer

scientific article published on 01 January 2002

Identification of potential biomarkers of head and neck squamous cell carcinoma using iTRAQ based quantitative proteomic approach

scientific article published on 24 May 2018

Immune profiles in primary squamous cell carcinoma of the head and neck

scientific article published on 12 July 2019

In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development.

scientific article

In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia

scientific article published on 22 May 2017

Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung

scientific article (publication date: July 2002)

Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer

scientific article

Increased mitochondrial DNA content in saliva associated with head and neck cancer

scientific article published in April 2005

Increased plasma DNA integrity index in head and neck cancer patients

scientific article published in December 2006

Inhibition of TGF-β enhances the in vivo antitumor efficacy of EGF receptor-targeted therapy

scientific article published on 27 August 2012

Integrated analysis of whole-genome ChIP-Seq and RNA-Seq data of primary head and neck tumor samples associates HPV integration sites with open chromatin marks

scientific article published on 25 September 2017

Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment

scientific article

Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma

scientific article

Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1)

scientific article

Intraoperative molecular margin analysis in head and neck cancer

scientific article published on 01 January 2004

Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma

scientific article published on 13 March 2007

Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing

scientific article published on September 2004

Inverse relationship between human papillomavirus-16 infection and disruptive p53 gene mutations in squamous cell carcinoma of the head and neck

scientific article published on 01 January 2008

Involvement of aquaporins in colorectal carcinogenesis

scientific article published on October 2003

Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use.

scientific article

JAK3 Variant, Immune Signatures, DNA Methylation, and Social Determinants Linked to Survival Racial Disparities in Head and Neck Cancer Patients

scientific article published on 18 February 2019

KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses

scientific article

KRAS mutation status is associated with enhanced dependency on folate metabolism pathways in non-small cell lung cancer cells

scientific article published on 31 March 2014

Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer

scientific article

LKB1 protein expression in the evolution of glandular neoplasia of the lung.

scientific article published in August 2003

LKB1/STK11 suppresses cyclooxygenase-2 induction and cellular invasion through PEA3 in lung cancer.

scientific article published on August 2006

LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer

scientific article published on 24 April 2007

Lack of BRAF mutation in primary uveal melanoma.

scientific article published in July 2003

Lactoferrin down-regulates G1 cyclin-dependent kinases during growth arrest of head and neck cancer cells

scientific article published on 01 December 2004

Local controlled delivery of anti-neoplastic RNAse to the brain

scientific article

Long-Term Cigarette Smoke Exposure and Changes in MiRNA Expression and Proteome in Non-Small-Cell Lung Cancer.

scientific article published on July 2017

Loss of chromosome arms 3p and 9p and inactivation ofP16INK4a in normal epithelium of patients with primary lung cancer

article

Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer

scientific article published on 01 March 2005

MAP2K1 is a potential therapeutic target in erlotinib resistant head and neck squamous cell carcinoma

scientific article published on 11 December 2019

MDA-9/Syntenin regulates differentiation and angiogenesis programs in head and neck squamous cell carcinoma

scientific article

MGMT inactivation and clinical response in newly diagnosed GBM patients treated with Gliadel

scientific article published on 3 August 2015

MT1G hypermethylation is associated with higher tumor stage in prostate cancer

scientific article

Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer.

scientific article published on 4 November 2015

Membrane trafficking of AQP5 and cAMP dependent phosphorylation in bronchial epithelium

scientific article

Methylation of death-associated protein kinase is associated with cetuximab and erlotinib resistance ⬇️

scientific article published on April 15, 2012

Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer

scientific article

Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing ⬇️

scientific article published on 01 May 2003

MicroRNA alterations in head and neck squamous cell carcinoma.

scientific article

Microsatellite analysis of serum DNA in patients with head and neck cancer

scientific article

Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes

scientific article

Milk derived colloid as a novel drug delivery carrier for breast cancer

scientific article

Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation.

scientific article published in July 2002

Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma

scientific article published on 01 February 2002

Mitochondrial DNA alterations in thyroid cancer

scientific article published on 01 March 2003

Mitochondrial DNA as a cancer biomarker

scientific article published on May 2005

Mitochondrial DNA content increase in response to cigarette smoking

scientific article published in January 2006

Mitochondrial DNA mutation in normal margins and tumors of recurrent head and neck squamous cell carcinoma patients

scientific article published on 26 July 2010

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: a biomarker for the early detection of cancer

scientific article published on 13 December 2006

Mitochondrial DNA mutations in respiratory complex‐I in never‐smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutation ⬇️

scientific article published on June 1, 2012

Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer.

scientific article

Mitochondrial subversion in cancer

scientific article published in May 2011

Molecular Characterization of Esophageal Squamous Cell Carcinoma Using Quantitative Proteomics

scientific article published on 23 June 2023

Molecular Profiling of Malignant Pleural Effusion in Metastatic Non-Small-Cell Lung Carcinoma. The Effect of Preanalytical Factors

scientific article

Molecular Triage of Premalignant Lesions in Liquid-Based Cervical Cytology and Circulating Cell-Free DNA from Urine, Using a Panel of Methylated Human Papilloma Virus and Host Genes.

scientific article published on 26 September 2016

Molecular alterations associated with chronic exposure to cigarette smoke and chewing tobacco in normal oral keratinocytes

scientific article published on 3 May 2018

Molecular analysis of peritoneal fluid in ovarian cancer patients.

scientific article

Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation-specific PCR

scientific article

Molecular assessment of lymph nodes in patients with resected stage I non-small cell lung cancer: preliminary results of a prospective study

scientific article published on 01 March 2002

Molecular detection approaches for smoking associated tumors.

scientific article

Molecular margin analysis predicts local recurrence after sublobar resection of lung cancer

scientific article published on 01 March 2005

Molecular markers of radiation effectiveness in head and neck squamous cell carcinoma

scientific article published on April 2004

Molecular techniques and genetic alterations in head and neck cancer

scientific article published on 31 July 2008

Mouse mammary tumor-likeenv gene as a molecular marker for breast cancer?

article

Multi-Omics Analysis to Characterize Cigarette Smoke Induced Molecular Alterations in Esophageal Cells

scientific article published on 05 November 2020

Multiomic analysis of oral keratinocytes chronically exposed to shisha

scientific article published on 15 February 2019

Multiple strand displacement amplification of mitochondrial DNA from clinical samples

scientific article

Mutation of p53 in head and neck squamous cell carcinoma correlates with Bcl-2 expression and increased susceptibility to cisplatin-induced apoptosis

scientific article published on October 2004

Mutational activation of BRAF is not a major event in sporadic childhood papillary thyroid carcinoma

scientific article published on July 2005

Mutational analysis of BRAF in fine needle aspiration biopsies of the thyroid: a potential application for the preoperative assessment of thyroid nodules

scientific article published in April 2004

Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma

scientific article published on 01 March 2003

N-methyl-D-aspartate receptor type 2B is epigenetically inactivated and exhibits tumor-suppressive activity in human esophageal cancer.

scientific article published on April 2006

NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis

scientific article published on 24 November 2017

Neurofilament heavy polypeptide regulates the Akt-beta-catenin pathway in human esophageal squamous cell carcinoma

scientific article (publication date: 3 February 2010)

Notch1 mutations are drivers of oral tumorigenesis

scientific article

OGDHL is a modifier of AKT-dependent signaling and NF-κB function

scientific article

OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation.

scientific article

Optimal use of a panel of methylation markers with GSTP1 hypermethylation in the diagnosis of prostate adenocarcinoma

scientific article published in August 2004

Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation

scientific article published on June 2008

Overexpression of c-met as a prognostic indicator for transitional cell carcinoma of the urinary bladder: a comparison with p53 nuclear accumulation

scientific article published in March 2002

Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer

scientific article published on October 2006

Oxidized guanine lesions and hOgg1 activity in lung cancer.

scientific article published in June 2005

PARD3 Inactivation in Lung Squamous Cell Carcinomas Impairs STAT3 and Promotes Malignant Invasion.

scientific article

PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus and overall survival

scientific article published on July 2013

PGP9.5 methylation in diffuse-type gastric cancer

scientific article published on April 2006

PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma

scientific article published on June 2005

PIM1 kinase promotes gallbladder cancer cell proliferation via inhibition of proline-rich Akt substrate of 40 kDa (PRAS40)

scientific article published on 21 January 2019

PUMA in head and neck cancer

scientific article (publication date: 10 September 2003)

Paired box 5 methylation detection by droplet digital PCR for ultra-sensitive deep surgical margins analysis of head and neck squamous cell carcinoma

scientific article

Pathway activation strength is a novel independent prognostic biomarker for cetuximab sensitivity in colorectal cancer patients

scientific article published on 2 April 2015

Patient-derived xenografts for individualized care in advanced sarcoma.

scientific article

Performance of mitochondrial DNA mutations detecting early stage cancer

scientific article

Pharmacologic unmasking of epigenetically silenced genes in breast cancer

scientific article

Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.

scientific article

Phospho-DeltaNp63alpha/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure

scientific article

Positive Correlation of Tissue Inhibitor of Metalloproteinase-3 and Death-Associated Protein Kinase Hypermethylation in Head and Neck Squamous Cell Carcinoma

scientific article published on 01 August 2007

Precision health diagnostic and surveillance network uses S gene target failure (SGTF) combined with sequencing technologies to track emerging SARS-CoV-2 variants

scientific article published on 01 June 2022

Prenatal exposure to tobacco smoke leads to increased mitochondrial DNA content in umbilical cord serum associated to reduced gestational age.

scientific article published on February 2017

Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome

scientific article

Prioritizing Phase I Treatment Options Through Preclinical Testing on Personalized Tumorgraft ⬇️

scientific article published on December 19, 2011

Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma

scientific article published on 26 May 2016

Profiling the expression pattern of GPI transamidase complex subunits in human cancer

scientific article

Prognostic Significance of Promoter DNA Hypermethylation of cysteine dioxygenase 1 (CDO1) Gene in Primary Breast Cancer

scientific article published on 19 January 2016

Prognostic biomarkers in patients with human immunodeficiency virus-positive disease with head and neck squamous cell carcinoma

scientific article published on 25 September 2017

Prognostic significance of preoperative molecular serum analysis in renal cancer

scientific article published on 01 June 2002

Progression of microsatellite instability from premalignant lesions to tumors of the head and neck

scientific article published on 01 December 2002

Promoter DNA methylation of oncostatin m receptor-beta as a novel diagnostic and therapeutic marker in colon cancer

scientific article

Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy

scientific article published in December 2005

Promoter methylation of MCAM, ERα and ERβ in serum of early stage prostate cancer patients

scientific article published on 28 January 2017

Promoter methylation of heat shock protein B2 in human esophageal squamous cell carcinoma ⬇️

scientific article published on January 21, 2011

Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma ⬇️

scientific article published on May 23, 2011

Proteomic Changes in Oral Keratinocytes Chronically Exposed to Shisha (Water Pipe)

scientific article published on 01 February 2019

Proteomic analysis of cancer-cell mitochondria ⬇️

scientific article published on October 1, 2003

Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection

scientific article published on July 2006

Quantitative GSTP1 Methylation and the Detection of Prostate Adenocarcinoma in Sextant Biopsies ⬇️

scientific article published on November 5, 2003

Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer

scientific article published in December 2002

Quantitative GSTP1 methylation clearly distinguishes benign prostatic tissue and limited prostate adenocarcinoma

scientific article

Quantitative GSTP1 methylation levels correlate with Gleason grade and tumor volume in prostate needle biopsies.

scientific article

Quantitative RARbeta2 hypermethylation: a promising prostate cancer marker

scientific article

Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer

scientific article published on 01 January 2002

Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission

scientific article published on June 2010

Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer.

scientific article

Quantitative hypermethylation of NMDAR2B in human gastric cancer.

scientific article

Quantitative hypermethylation of a small panel of genes augments the diagnostic accuracy in fine-needle aspirate washings of breast lesions

article

Quantitative methylation profiles for multiple tumor suppressor gene promoters in salivary gland tumors

scientific article (publication date: 26 May 2010)

Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects.

scientific article

RACK1 and stratifin target DeltaNp63alpha for a proteasome degradation in head and neck squamous cell carcinoma cells upon DNA damage

scientific article

RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI-associated endometrial carcinoma

scientific article

Ranpirnase eradicates human papillomavirus in cultured cells and heals anogenital warts in a Phase I study

scientific article

Re: Is TIG1 a new tumor suppressor in prostate cancer?

scientific article published on 01 June 2003

Real-time gap ligase chain reaction: a rapid semiquantitative assay for detecting p53 mutation at low levels in surgical margins and lymph nodes from resected lung and head and neck tumors

scientific article published on 01 April 2004

Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity

scientific article published on 01 May 2002

Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase beta

scientific article

Regulation of ΔNp63α by NFκΒ

scientific article

Repurposing the FDA-Approved Antiviral Drug Ribavirin as Targeted Therapy for Nasopharyngeal Carcinoma

scientific article published on 30 June 2020

Ribonucleases as a novel pro-apoptotic anticancer strategy: review of the preclinical and clinical data for ranpirnase

scientific article published in January 2005

Role of human aquaporin 5 in colorectal carcinogenesis

scientific article published on 26 June 2008

Role of protein kinase N2 (PKN2) in cigarette smoke-mediated oncogenic transformation of oral cells.

scientific article

SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling

scientific article published on 12 September 2012

SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells.

scientific article

Screening of homologous recombination gene polymorphisms in lung cancer patients reveals an association of the NBS1-185Gln variant and p53 gene mutations

article

Secretome analysis of oral keratinocytes chronically exposed to shisha

scientific article published on 01 January 2019

Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244.

scientific article

Sensitization to UV-induced apoptosis by the histone deacetylase inhibitor trichostatin A (TSA).

scientific article

Serum protein MALDI profiling to distinguish upper aerodigestive tract cancer patients from control subjects

scientific article

Signaling alterations in oral keratinocytes in response to shisha and crude tobacco extract

scientific article published on 28 December 2020

Silencing of high-mobility group box 2 (HMGB2) modulates cisplatin and 5-fluorouracil sensitivity in head and neck squamous cell carcinoma

scientific article published in January 2015

Slow development impedes the uptake of diagnostics

scientific article published on 01 January 2008

Somatic mitochondrial mutation discovery using ultra-deep sequencing of the mitochondrial genome reveals spatial tumor heterogeneity in head and neck squamous cell carcinoma

scientific article published on 10 December 2019

Somatic mutation and gain of copy number of PIK3CA in human breast cancer

scientific article

Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma

scientific article published in October 2003

Suprabasin is hypomethylated and associated with metastasis in salivary adenoid cystic carcinoma

scientific article

T1799A BRAF mutations in conjunctival melanocytic lesions.

scientific article

TAp63gamma regulates hOGG1 and repair of oxidative damage in cancer cell lines

scientific article published on 7 February 2007

TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

scientific article

Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA

scientific article

Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor.

scientific article published in January 2018

Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress

scientific article published on 3 October 2006

The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection.

scientific article published on May 2004

The KRAS-Variant and Cetuximab Response in Head and Neck Squamous Cell Cancer: A Secondary Analysis of a Randomized Clinical Trial

scientific article published on 22 December 2016

The Ligamp TP53 Assay for Detection of Minimal Residual Disease in Head and Neck Squamous Cell Carcinoma Surgical Margins

scientific article

The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix.

scientific article

The Ras effector RASSF2 controls the PAR-4 tumor suppressor

scientific article

The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors ⬇️

scientific article published on July 31, 2013

The TGFβ-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors

scientific article published on 15 May 2014

The V599E BRAF mutation is uncommon in biliary tract cancers

scientific article

The effect of aquaporin 5 overexpression on the Ras signaling pathway

scientific article published on 26 December 2007

The effect of p53-RNAi and p53 knockout on human 8-oxoguanine DNA glycosylase (hOgg1) activity

scientific article

The oral cavity as a molecular mirror of lung carcinogenesis

scientific article published in June 2008

The role of PGP9.5 as a tumor suppressor gene in human cancer

scientific article

Tissue and Cell-Free DNA-Based Epigenomic Approaches for Cancer Detection

scientific article published on 16 December 2019

Tissue imprint for molecular mapping of deep surgical margins in patients with head and neck squamous cell carcinoma ⬇️

scientific article published on January 3, 2012

Tissue inhibitor of metalloproteinases-3 promoter methylation is an independent prognostic factor for bladder cancer.

scientific article published on 20 December 2007

Tumor Protein p63/Nuclear Factor κB Feedback Loop in Regulation of Cell Death ⬇️

scientific article published on October 20, 2011

Tumor-specific changes in mtDNA content in human cancer

scientific article

Tyrosine Phosphorylation Profiling Revealed the Signaling Network Characteristics of CAMKK2 in Gastric Adenocarcinoma

scientific article published on 13 May 2022

U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha

scientific article

Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors

scientific article published on 31 May 2005

Understanding the MIG6-EGFR Signaling Axis in Lung Tumorigenesis

scientific article published in May 2015

Use of single nucleotide polymorphism arrays to identify a novel region of loss on chromosome 6q in squamous cell carcinomas of the oral cavity

scientific article published on 01 April 2004

Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer

scientific article published on 16 December 2013

Words matter: distinguishing "personalized medicine" and "biologically personalized therapeutics"

scientific article

YAP1 and COX2 Coordinately Regulate Urothelial Cancer Stem-like Cells

scientific article published on 27 November 2017

Yes-associated protein 1 regulates the stability of DeltaNp63alpha

scientific article

miRNA and proteomic dysregulation in non-small cell lung cancer in response to cigarette smoke

scientific article published on 3 January 2018

p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways

scientific article published on 2 March 2010

p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study

scientific article published in July 2003

p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma ⬇️

scientific article published on December 15, 2010

p63 and p73: teammates or adversaries?

scientific article

p63 transcriptional regulation of epithelial integrity and cancer

scientific article published on 3 February 2007

p63-specific activation of the BPAG-1e promoter

scientific journal article

p63α Mutations Lead to Aberrant Splicing of Keratinocyte Growth Factor Receptor in the Hay-Wells Syndrome ⬇️

scientific article (publication date: 27 June 2003)

ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer

scientific article published on June 2008

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