List of works - Andreas Ebneth

Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity

scientific article

Characterization of HTT inclusion size, location, and timing in the zQ175 mouse model of Huntington's disease: an in vivo high-content imaging study

scientific article

Corrigendum to "Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line" [Stem Cell Res. 34/1873-5061 (2019) 101349-55]

scientific article published on 21 September 2020

Deploying human pluripotent stem cells to treat central nervous system disorders: facts, challenges and realising the potential

scientific article published on 16 October 2019

Development of LC/MS/MS, High-Throughput Enzymatic and Cellular Assays for the Characterization of Compounds That Inhibit Kynurenine Monooxygenase (KMO) ⬇️

scientific article published on May 20, 2013

Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders

scientific article published on 16 November 2020

Discovery and structure-activity relationship of potent and selective covalent inhibitors of transglutaminase 2 for Huntington's disease.

scientific article

Evaluation of a high-throughput fluorescence assay method for HERG potassium channel inhibition

scientific article published in June 2005

Fragment-based discovery of BACE1 inhibitors using functional assays

scientific article

Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration

scientific article published on 20 July 2018

Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line

scientific article published on 04 January 2019

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes

scientific article published on 01 August 2019

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.

scientific article published on 26 July 2018

HTS techniques to investigate the potential effects of compounds on cardiac ion channels at early-stages of drug discovery.

scientific article

Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

scientific article published on 15 February 2017

Identification and functional characterization of a novel KCNE2 (MiRP1) mutation that alters HERG channel kinetics

scientific article

Imaging Mutant Huntingtin Aggregates: Development of a Potential PET ligand

scientific article published on 14 July 2020

Ion channel screening technologies: will they revolutionize drug discovery?

scientific article published on 01 February 2002

MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes

scientific article

Morpholine containing CB2 selective agonists

scientific article

Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience

scientific article

SliceMap: An Algorithm for Automated Brain Region Annotation.

scientific article published on 18 October 2017

Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis

scientific article published on 19 July 2019

Systemic immune-checkpoint blockade with anti-PD1 antibodies does not alter cerebral amyloid-β burden in several amyloid transgenic mouse models

scientific article

The EBiSC iPSC bank for disease studies

scientific article published on 09 October 2020

The novel KMO inhibitor CHDI-340246 leads to a restoration of electrophysiological alterations in mouse models of Huntington's disease.

scientific article published on 6 May 2016

The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding

scientific article

Using electrophysiology and in silico three-dimensional modeling to reduce human Ether-à-go-go related gene K(+) channel inhibition in a histamine H3 receptor antagonist program

scientific article published on 6 December 2010

List of works by Andreas Ebneth

Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity

Characterization of HTT inclusion size, location, and timing in the zQ175 mouse model of Huntington's disease: an in vivo high-content imaging study

Corrigendum to "Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line" [Stem Cell Res. 34/1873-5061 (2019) 101349-55]

Deploying human pluripotent stem cells to treat central nervous system disorders: facts, challenges and realising the potential

Development of LC/MS/MS, High-Throughput Enzymatic and Cellular Assays for the Characterization of Compounds That Inhibit Kynurenine Monooxygenase (KMO) ⬇️

Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders

Discovery and structure-activity relationship of potent and selective covalent inhibitors of transglutaminase 2 for Huntington's disease.

Evaluation of a high-throughput fluorescence assay method for HERG potassium channel inhibition

Fragment-based discovery of BACE1 inhibitors using functional assays

Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration

Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.

HTS techniques to investigate the potential effects of compounds on cardiac ion channels at early-stages of drug discovery.

Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

Identification and functional characterization of a novel KCNE2 (MiRP1) mutation that alters HERG channel kinetics

Imaging Mutant Huntingtin Aggregates: Development of a Potential PET ligand

Ion channel screening technologies: will they revolutionize drug discovery?

MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes

Morpholine containing CB2 selective agonists

Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience

SliceMap: An Algorithm for Automated Brain Region Annotation.

Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis

Systemic immune-checkpoint blockade with anti-PD1 antibodies does not alter cerebral amyloid-β burden in several amyloid transgenic mouse models

The EBiSC iPSC bank for disease studies

The novel KMO inhibitor CHDI-340246 leads to a restoration of electrophysiological alterations in mouse models of Huntington's disease.

The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding

Using electrophysiology and in silico three-dimensional modeling to reduce human Ether-à-go-go related gene K(+) channel inhibition in a histamine H3 receptor antagonist program