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List of works by Angelika Bierhaus

(CA)(n) dinucleotide repeat polymorphism at the 5'-end of the aldose reductase gene is not associated with microangiopathy in Caucasians with long-term diabetes mellitus 1

scientific article published on 01 June 2000

A 63bp deletion in the promoter of rage correlates with a decreased risk for nephropathy in patients with type 2 diabetes

scientific article

A M55V polymorphism in the SUMO4 gene is associated with a reduced prevalence of diabetic retinopathy in patients with Type 1 diabetes

scientific article

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

scientific article

A mechanism converting psychosocial stress into mononuclear cell activation

scholarly article

A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival

scientific article

A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin

scientific article published on February 2007

A role for the receptor for advanced glycation end products in idiopathic pulmonary fibrosis

scientific journal article

A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)

scientific article published on 04 July 2008

AGE-modified albumin containing infusion solutions boosts septicaemia and inflammation in experimental peritonitis.

scientific article published on 28 April 2009

AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept ⬇️

scientific article published on March 1, 1998

Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis

scientific article published on 4 November 2007

Activation of NFκB dependent apoptotic pathway in pancreatic islet cells by hypoxia ⬇️

scientific article published on 01 July 2009

Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies?

scientific article published on 01 January 2007

Activation of the host response in human plasmodium falciparum malaria: Relation of parasitemia to tumor necrosis factor/cachectin, thrombin-antithrombin III, and protein C levels ⬇️

scientific article published on July 1, 1991

Activation of tubular epithelial cells in diabetic nephropathy

scientific article published in December 2002

Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor kappaB in PBMCs

scientific article published in March 2003

Adipocytokines as a novel target for the anti-inflammatory effect of atorvastatin in patients with type 2 diabetes

scientific article published in March 2005

Adult vascular progenitor cells and tissue regeneration in metabolic syndrome

scientific article

Advanced Glycation End Product (AGE)–Mediated Induction of Tissue Factor in Cultured Endothelial Cells Is Dependent on RAGE ⬇️

scientific article published on October 7, 1997

Advanced Glycation End Product-Induced Activation of NF-κB is Suppressed by α-Lipoic Acid in Cultured Endothelial Cells ⬇️

scientific article published on 01 September 1997

Advanced glycation end product receptor-mediated cellular dysfunction

scientific article

Aging-Dependent Reduction in Glyoxalase 1 Delays Wound Healing

scientific article published on 22 June 2013

Alagebrium reduces glomerular fibrogenesis and inflammation beyond preventing RAGE activation in diabetic apolipoprotein E knockout mice

scientific article

Androgen receptor isoforms AR-A and AR-B display functional differences in cultured human bone cells and genital skin fibroblasts

scientific article

Angiostatin is a novel anti-inflammatory factor by inhibiting leukocyte recruitment

scientific article published on 21 September 2004

Antiangiogenic properties of low molecular weight heparin - does tissue factor provide the answer?

scientific article published on 01 September 2004

Antiparasitic treatment of patients with P. falciparum malaria reduces the ability of patient serum to induce tissue factor by decreasing NF-kappa B activation.

scientific article

Apurinic/apyrimidinic endonuclease 1, p53, and thioredoxin are linked in control of aging in C. elegans

scientific article published on 24 March 2010

Aryl hydrocarbon receptor interacting protein gene (AIP) mutations are rare in patients with hormone secreting or non-secreting pituitary adenomas

scientific article published on 16 May 2008

Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes

scientific article published in January 2004

Association of homozygous SDF-1 3'A genotype with proliferative diabetic retinopathy

scientific article

Association of reduced glyoxalase 1 activity and painful peripheral diabetic neuropathy in type 1 and 2 diabetes mellitus patients

scientific article published on 23 January 2013

Association of stromal cell-derived factor 1 genotype with diabetic foot syndrome and macrovascular disease in patients with type 2 diabetes

scientific article published on 01 June 2006

Associations of fetuin-A levels with vascular disease in type 2 diabetes patients with early diabetic nephropathy.

scientific article

Atherosclerosis and restenosis: is there a role for RAGE?

scientific article

Bench-to-bedside review: The inflammation-perpetuating pattern-recognition receptor RAGE as a therapeutic target in sepsis

scientific article published on 09 January 2008

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

scientific article (publication date: 18 February 2003)

C. elegans as model for the study of high glucose- mediated life span reduction

scientific article published on 12 August 2009

C332C genotype of glyoxalase 1 and its association with late diabetic complications

scientific article published on 17 June 2013

CD166/ALCAM mediates proinflammatory effects of S100B in delayed type hypersensitivity

scientific article published on 31 May 2013

Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs.

scientific article published on 13 May 2008

Cell specific effects of glucocorticoid treatment on the NF-kappaBp65/IkappaBalpha system in patients with Crohn's disease

scientific article

Cellular infiltrates and NFκB subunit c-Rel signaling in kidney allografts of patients with clinical operational tolerance

scientific article published on October 2012

Central sympatholytics prolong survival in experimental sepsis

scientific article published on 06 February 2009

Changes in adiponectin multimer distribution in response to atorvastatin treatment in patients with type 2 diabetes

scientific article

Chemistry and pathobiology of advanced glycation end products.

scientific article

Chronic corticosterone-induced deterioration in rat behaviour is not paralleled by changes in hippocampal NF-kappaB-activation

scientific article published in June 2006

Clinical benefit of a short term dietary oatmeal intervention in patients with type 2 diabetes and severe insulin resistance: a pilot study

scientific article

Comment on: Lin et al. (2007) SUMO4 M55V variant is associated with diabetic nephropathy in type 2 diabetes: Diabetes 56: 1177-1180

scientific article published on 01 August 2007

Connexin 43 expression in normal and irradiated mouse skin

scientific article published on April 1997

Correction: Methylglyoxal Evokes Pain by Stimulating TRPA1.

scientific article published on 5 December 2013

Critical Evaluation of Mouse Models Used to Study Pain and Loss of Pain Perception in Diabetic Neuropathy ⬇️

scientific article published on 08 March 2012

Cyclosporin A Inhibits Monocyte Tissue Factor Activation in Cardiac Transplant Recipients ⬇️

scientific article published on December 16, 1997

Cyclosporine a inhibits tissue factor expression in monocytes/macrophages

scientific article published on 01 November 1996

Damage to the peritoneal membrane by glucose degradation products is mediated by the receptor for advanced glycation end-products

scientific article published on 30 November 2005

Decreased plasma lipoprotein lipase in hypoadiponectinemia: an association independent of systemic inflammation and insulin resistance

scientific article published in December 2004

Deletion of bone marrow-derived receptor for advanced glycation end products inhibits atherosclerotic plaque progression ⬇️

scientific article published on March 21, 2011

Depletion of the receptor for advanced glycation end products (RAGE) sensitizes towards apoptosis via p53 and p73 posttranslational regulation ⬇️

scientific article published on April 30, 2012

Determinants of the NF-kappaB response to acute psychosocial stress in humans

scientific article published on 26 September 2008

Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-κB ⬇️

scientific article (publication date: December 2001)

Differential effect of Rhizoma coptidis and its main alkaloid compound berberine on TNF-alpha induced NFkappaB translocation in human keratinocytes

scientific article published on 14 July 2006

Differential expression of CD44s and CD44v10 proteins and syndecan in normal and irradiated mouse epidermis

scientific article published on February 1997

Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy.

scientific article published on 16 December 2009

Distinct roles of Mac-1 and its counter-receptors in neonatal obstructive nephropathy

scientific article published in January 2006

Effect of R-(+)-alpha-lipoic acid on experimental diabetic retinopathy

scientific article published on 7 March 2006

Effects of stress reduction on cardiovascular risk factors in type 2 diabetes patients with early kidney disease - results of a randomized controlled trial (HEIDIS).

scientific article published on 05 May 2014

Effects of supplementation with alpha-lipoic acid on exercise-induced activation of coagulation

scientific article published in June 2005

Elevated thrombomodulin plasma levels as a result of endothelial involvement in plasmodium falciparum malaria

scientific article published on 01 September 1994

Endothelial dysfunction in diabetes mellitus

scientific article

Endothelial precursor cells and CRP on the RAGE: activation or cell death?

scientific article published in May 2009

Endothelial progenitor cells in regeneration after acute lung injury: do they play a role?

scientific article published on April 2013

Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells

scientific article published on September 2000

Erratum to: Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes

scholarly article published in Diabetologia

Erratum: Corrigendum: Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scholarly article published in Nature Medicine

Erythropoietin-mediated decrease of the redox-sensitive transcription factor NF-kappaB is inversely correlated with the hemoglobin level

scientific article published on 01 September 2002

Evidence of left ventricular contractile asynchrony by echocardiographic phase imaging in patients with type 2 diabetes mellitus and without clinically evident heart disease

scientific article published on 16 October 2006

Expression of CD44 isoforms during bleomycin-or radiation-induced pulmonary fibrosis in rats and mini-pigs

scientific article published on 01 March 1996

Expression of receptors for advanced glycation end products in peripheral occlusive vascular disease

scientific article published on March 1995

Expression of receptors for advanced glycation end-products in occlusive vascular and renal disease

scientific article published on January 1996

External electric muscle stimulation improves burning sensations and sleeping disturbances in patients with type 2 diabetes and symptomatic neuropathy

scientific article published on 16 January 2009

Functional polymorphisms of UCP2 and UCP3 are associated with a reduced prevalence of diabetic neuropathy in patients with type 1 diabetes

scientific article

Glimepiride reduces mononuclear activation of the redox-sensitive transcription factor nuclear factor-kappa B.

scientific article

Glucose, glycation, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy

scientific article

Glycated and carbamylated albumin are more “nephrotoxic” than unmodified albumin in the amphibian kidney ⬇️

scientific article published on March 2, 2011

Glycotoxins and cellular dysfunction. A new mechanism for understanding the preventive effects of lifestyle modifications

scientific article published in August 2006

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

scientific article published on 21 January 2008

HMGB1 as a predictor of infarct transmurality and functional recovery in patients with myocardial infarction ⬇️

scientific article published on March 28, 2011

HMGB1 is associated with atherosclerotic plaque composition and burden in patients with stable coronary artery disease

scientific article

HMGB1: the missing link between diabetes mellitus and heart failure

scientific article published on 12 August 2010

High mobility group box 1 prolongs inflammation and worsens disease in pneumococcal meningitis

scientific article published on 21 March 2013

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

article

High-molecular weight adiponectin is independently associated with the extent of coronary artery disease in men.

scientific article published on 19 November 2007

Hochfrequente Muskelstimulation zur Behandlung schmerzhafter Neuropathie bei Typ 2 Diabetikern verbessert die mikrovaskuläre Endothelzellfunktion

Hypercoagulability inhibits monocyte transendothelial migration through protease-activated receptor-1-, phospholipase-Cbeta-, phosphoinositide 3-kinase-, and nitric oxide-dependent signaling in monocytes and promotes plaque stability

scientific journal article

Hyperhomocyst(e)inemia and Endothelial Dysfunction in IDDM ⬇️

scientific article published on December 1, 1997

Hyperhomocyst(e)inemia and endothelial dysfunction in IDDM.

scientific article published in May 1998

Identical LDL-cholesterol lowering but non-identical effects on NF-κB activity: High dose simvastatin vs combination therapy with ezetimibe ⬇️

scientific article published on 07 May 2012

Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation

scientific article

Impact of autonomic neuropathy on left ventricular function in normotensive type 1 diabetic patients: a tissue Doppler echocardiographic study: response to Karamitsos et al

scientific article published on 01 May 2008

Improved vascular function upon pioglitazone treatment in type 2 diabetes is not associated with changes in mononuclear NF-kappaB binding activity

scientific article published on 01 September 2007

Inactivation of AP1 proteins by a nuclear serine protease precedes the onset of radiation-induced fibrosing alveolitis

scientific journal article

Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end products

scientific article published on 30 March 2006

Insufficient Glycemic Control Increases Nuclear Factor-κB Binding Activity in Peripheral Blood Mononuclear Cells Isolated From Patients With Type 1 Diabetes ⬇️

scientific article published on August 1, 1998

Insulin stimulates the clonogenic potential of angiogenic endothelial progenitor cells by IGF-1 receptor-dependent signaling

scientific article

Intravenous somatic gene transfer with antisense tissue factor restores blood flow by reducing tumor necrosis factor-induced tissue factor expression and fibrin deposition in mouse meth-A sarcoma

scientific article published on May 1996

Is diabetes an acquired disorder of reactive glucose metabolites and their intermediates? ⬇️

scientific article published on January 22, 2012

Kidney injury molecule-1 and the loss of kidney function in diabetic nephropathy: a likely causal link in patients with type 1 diabetes

scientific article

L-arginine and asymmetric dimethylarginine are early predictors for survival in septic patients with acute liver failure

scientific article

LPS and cytokine-activated endothelium

scientific article

Lack of association between polymorphisms of the toll-like receptor 4 gene and cerebral ischemia

scientific article published on 01 July 2004

Left ventricular diastolic function in type 2 diabetes mellitus is associated with myocardial triglyceride content but not with impaired myocardial perfusion reserve ⬇️

scientific article published on November 8, 2011

Levels of three distinct p75 neurotrophin receptor forms found in human plasma are altered in type 2 diabetic patients

scientific article published on 11 May 2007

Linking stress to inflammation

scientific article published on June 2006

Locally applied mononuclear bone marrow cells restore angiogenesis and promote wound healing in a type 2 diabetic patient

scientific article published on 01 October 2005

Long-term treatment of central Cushing's syndrome with rosiglitazone

scientific article published on 01 May 2007

Loss of caveolin expression in type I pneumocytes as an indicator of subcellular alterations during lung fibrogenesis

scientific article published on 01 January 1998

Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily

scientific article

Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy

scientific article published on 09 March 2011

Low levels of sRAGE are associated with increased risk for mortality in renal transplant recipients

scientific article published in September 2007

Macrophage migration inhibitory factor (MIF) and manganese superoxide dismutase (MnSOD) as early predictors for survival in patients with severe sepsis or septic shock

scientific article published in June 2010

Maturing dendritic cells depend on RAGE for in vivo homing to lymph nodes

scientific article published on 01 February 2008

Maturity-Onset Diabetes of the Young (MODY) caused by a Novel Nonsense Mutation E41X in the HNF-1α Gene ⬇️

scientific article published on August 5, 2010

Mechanism of endothelial cell activation

scientific article published on 01 April 1993

Mechanism of the tumor necrosis factor alpha-mediated induction of endothelial tissue factor

scientific article published on 01 November 1995

Methylglyoxal activates nociceptors through transient receptor potential channel A1 (TRPA1): a possible mechanism of metabolic neuropathies

scientific article published on 27 June 2012

Methylglyoxal as a new biomarker in patients with septic shock: an observational clinical study

scientific article

Methylglyoxal evokes pain by stimulating TRPA1

scientific article (publication date: 2013)

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scientific article

Minocycline reduces plaque size in diet induced atherosclerosis via p27(Kip1).

scientific article

Modulation of the vascular endothelium during infection--the role of NF-kappa B activation

scientific article

Molecular Mechanisms of Diabetic Angiopathy – Clues for Innovative Therapeutic Interventions ⬇️

scientific article published on January 1, 1998

Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications

scientific article published on 28 July 2009

NF-kappaB as a molecular link between psychosocial stress and organ dysfunction

scientific article published on 20 August 2004

New aspects of integrin-mediated leukocyte adhesion in inflammation: regulation by haemostatic factors and bacterial products

scientific article

New treatments for diabetic neuropathy: Pathogenetically oriented treatment ⬇️

scientific article published on December 1, 2003

No association of the 94T/G polymorphism in the adiponectin gene with diabetic complications

scientific article published in July 2005

Nuclear factor erythroid-derived 2 (Nfe2) regulates JunD DNA-binding activity via acetylation: a novel mechanism regulating trophoblast differentiation

scientific article published on 15 December 2011

Nε-(carboxymethyl)lysine-receptor for advanced glycation end product axis is a key modulator of obesity-induced dysregulation of adipokine expression and insulin resistance

scientific article published on 10 April 2014

Osteoporosis and cardiovascular disease--two sides of the same coin?

scientific article published in August 2003

Participation of the receptor for advanced glycation end products in efferocytosis

scientific article published on 18 April 2011

Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kappaB

scientific article published on 01 February 1999

Pharmacologic cholinesterase inhibition improves survival in experimental sepsis.

scientific article

Plasma sRAGE is independently associated with urinary albumin excretion in type 2 diabetes

scientific article published on 01 May 2006

Postprandial mononuclear NF-kappaB activation is independent of the AGE-content of a single meal

scientific article published on 01 April 2006

Posttranslational modification of lipoproteins--a fatal attraction in metabolic disease?

scientific article published in August 2005

Posttranslationally modified proteins as mediators of sustained intestinal inflammation

scientific article published on October 2006

Promoter polymorphisms of UCP1, UCP2, and UCP3 are not associated with diabetic microvascular complications in type 2 diabetes

scientific article published on 01 April 2007

Protective effects and anti-inflammatory pathways of exogenous calcitonin gene-related peptide in severe necrotizing pancreatitis

scientific article published on 14 August 2009

Protein C concentrate controls leukocyte recruitment during inflammation and improves survival during endotoxemia after efficient in vivo activation

scientific article published on 9 September 2011

Proximal neuropathic lesions in distal symmetric diabetic polyneuropathy: findings of high-resolution magnetic resonance neurography

scientific article

Quinapril treatment abolishes diabetes-associated atherosclerosis in RAGE/apolipoprotein E double knockout mice.

scientific article published on 4 June 2014

RAGE (receptor for advanced glycation end products): a central player in the inflammatory response

scientific article published in November 2004

RAGE Does Not Contribute to Renal Injury and Damage upon Ischemia/Reperfusion-Induced Injury

scientific article published on 04 November 2011

RAGE Signaling in Cell Adhesion and Inflammation

RAGE and Alzheimer's disease: a progression factor for amyloid-beta-induced cellular perturbation?

scientific article published on January 2009

RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo

scientific article published on 20 April 2010

RAGE and ICAM-1 differentially control leukocyte recruitment during acute inflammation in a stimulus-dependent manner

scientific article

RAGE does not affect amyloid pathology in transgenic ArcAbeta mice.

scientific article published in January 2009

RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy

scientific article published on April 2003

RAGE expression in the human peritoneal membrane

scientific article published on 13 May 2008

RAGE in inflammation: a new therapeutic target?

scientific article published on November 2006

RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides

scientific article

RAGE regulates immune cell infiltration and angiogenesis in choroidal neovascularization.

scientific article

RAGE signaling sustains inflammation and promotes tumor development

scientific article published on 21 January 2008

RAGE supports parathyroid hormone-induced gains in femoral trabecular bone

scientific article

RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis

scientific article

RAGE-dependent activation of gene expression of superoxide dismutase and vanins by AGE-rich extracts in mice cardiac tissue and murine cardiac fibroblasts

scientific article

RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.

scientific article published on 21 January 2009

RAGE-mediated interstitial fibrosis in neonatal obstructive nephropathy is independent of NF-κB activation ⬇️

scientific article published on May 15, 2013

Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging process: a mini-review

scientific article published on 21 October 2010

Reactive oxygen species in diabetes-induced vascular damage, stroke, and Alzheimer's disease

scientific article published on January 2009

Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor.

scientific article published on 15 July 2010

Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia

scientific article published on 29 January 2016

Receptor for advanced glycation end product expression in experimental diabetic retinopathy

scientific article published in April 2008

Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes

scientific article published on 28 May 2008

Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response

scientific article

Receptor for advanced glycation end products facilitates host defense during Escherichia coli-induced abdominal sepsis in mice

scientific article published on 01 September 2009

Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia.

scientific article

Receptor for advanced glycation end products is protective during murine tuberculosis

scientific article

Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases

scientific article published on 24 October 2008

Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.

scientific article

Receptor for advanced glycation endproduct (RAGE)-mediated nuclear factor-kappaB activation in vasculitic neuropathy

scientific article

Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicity

scientific article published on 9 January 2012

Receptor for advanced glycation endproducts (RAGE) is a key regulator of oval cell activation and inflammation-associated liver carcinogenesis in mice.

scientific article published in July 2013

Receptors for advanced glycation end-products targeting protect against hyperoxia-induced lung injury in mice

scientific article published on 18 June 2009

Reduction of postprandial hyperglycemia in patients with type 2 diabetes reduces NF-kappaB activation in PBMCs

scientific article

Regulation of osteoclast function and bone mass by RAGE.

scientific article

Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor

scientific article published on July 1999

Release of thrombomodulin from endothelial cells by concerted action of TNF-alpha and neutrophils: in vivo and in vitro studies

scientific article published on 01 January 1996

Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with type 2 diabetes or coronary artery disease

scientific article published on 18 July 2007

Role of NFkappaB in the mortality of sepsis ⬇️

scientific article published on September 1, 1997

Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice.

scientific article

Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo

scientific article

Rosiglitazone reduces angiotensin II and advanced glycation end product-dependent sustained nuclear factor-kappaB activation in cultured human proximal tubular epithelial cells

scientific article published on 18 August 2008

S100A8/A9 aggravates post-ischemic heart failure through activation of RAGE-dependent NF-κB signaling ⬇️

scientific article published on February 10, 2012

SDF-1 genotype influences insulin-dependent mobilization of adult progenitor cells in type 2 diabetes

scientific article published in April 2005

Serum soluble receptor for advanced glycation end products (sRAGE) is independently associated with cigarette smoking in non-diabetic healthy subjects

scientific article published on 21 March 2013

Skin-autofluorescence is an independent predictor of graft loss in renal transplant recipients.

scientific article published in April 2009

Soluble RAGE but not endogenous secretory RAGE is associated with albuminuria in patients with type 2 diabetes

scientific article published on 7 March 2007

Sp1-dependent regulation of PPARα in bone metabolism

scientific article published on January 2014

Sustained effects of a mindfulness-based stress-reduction intervention in type 2 diabetic patients: design and first results of a randomized controlled trial (the Heidelberger Diabetes and Stress-study).

scientific article published on 14 February 2012

Targeted reduction of advanced glycation improves renal function in obesity

scientific article published on 16 March 2011

Targeting Activation of Specific NF-κB Subunits Prevents Stress-Dependent Atherothrombotic Gene Expression ⬇️

scientific article published on December 20, 2012

The -174G>C IL-6 gene promoter polymorphism and diabetic microvascular complications

scientific article published on 12 January 2009

The 20210 G to A prothrombin polymorphism and late complications in type 1 diabetes mellitus

scientific article published on 01 January 1999

The AGE/RAGE/NF-(kappa)B pathway may contribute to the pathogenesis of polyneuropathy in impaired glucose tolerance (IGT).

scientific article published in May 2005

The Alzheimer's disease-diabetes angle: inevitable fate of aging or metabolic imbalance limiting successful aging. Preface

scientific article published on 01 January 2009

The Complexity of Sporadic Alzheimer’s Disease Pathogenesis: The Role of RAGE as Therapeutic Target to Promote Neuroprotection by Inhibiting Neurovascular Dysfunction ⬇️

scientific article published on March 11, 2012

The DG10S478 variant in the TCF7L2 gene is not associated with microvascular complications in type 2 diabetes

scientific article published on 10 December 2007

The HMGB1 receptor RAGE mediates ischemic brain damage

scientific article

The RAGE pathway in inflammatory myopathies and limb girdle muscular dystrophy

scientific article

The RAGE pathway: activation and perpetuation in the pathogenesis of diabetic neuropathy

scientific article published on 01 April 2008

The dietary pigment curcumin reduces endothelial tissue factor gene expression by inhibiting binding of AP-1 to the DNA and activation of NF-kappa B

scientific article published on 01 April 1997

The lectin-like domain of thrombomodulin ameliorates diabetic glomerulopathy via complement inhibition

scientific article published on 26 September 2012

The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment

scientific article published on November 2003

The receptor for advanced glycation end products impairs host defense in pneumococcal pneumonia

scientific article published in April 2009

The receptor for advanced glycation end products is dispensable in a mouse model of oral and esophageal carcinogenesis

scientific article published on May 28, 2013

The role of oxidative stress and NF-kappaB activation in late diabetic complications

scientific article

Therapeutic effects of metformin in breast cancer: involvement of the immune system?

scientific article published on 17 June 2011

Tissue factor as a link between wounding and tissue repair.

scientific article

Tissue factor expression during human and mouse development

scientific article published on July 1996

Tissue factor expression in an animal model of hydronephrosis

scientific article published on 01 October 1995

Tissue factor--a receptor involved in the control of cellular properties, including angiogenesis

scientific article published on 01 July 2001

Tissue factor-dependent pathway is not involved in exercise-induced formation of thrombin and fibrin ⬇️

scientific article published on January 1, 2002

Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

scientific article (publication date: May 2007)

Tuning the volume of the immune response: strength and persistence of stimulation determine migration and cytokine secretion of dendritic cells

scientific article

Understanding RAGE, the receptor for advanced glycation end products

scientific article

Urinary Adiponectin Is an Independent Predictor of Progression to End-Stage Renal Disease in Patients With Type 1 Diabetes and Diabetic Nephropathy

Urinary L-FABP and anaemia: distinct roles of urinary markers in type 2 diabetes

scientific article published on 11 November 2009

Urinary adiponectin excretion: a novel marker for vascular damage in type 2 diabetes

scientific article published on 09 June 2009

Urinary excretion of high molecular weight adiponectin is an independent predictor of decline of renal function in type 2 diabetes

scientific article published on 24 December 2013

Urinary liver-type fatty acid binding protein is an independent predictor of stroke and mortality in individuals with type 1 diabetes

scientific article published on 10 June 2017

Urinary liver-type fatty acid-binding protein and progression of diabetic nephropathy in type 1 diabetes

scientific article published on February 2013

Urinary n-acetyl-beta-d-glucosaminidase excretion: an indicator of neuropathy in type 2 diabetes

scientific article published on 20 September 2013

[AGE-RAGE: a hypothesis or a mechanism?]

scientific article published on 01 August 2004

[Coagulation, inflammation and immune response -- an evolutionary conserved plan as cause for disseminated intravasal coagulation?]

scientific article published on 01 February 2005

[Liposome-mediated transfection of thrombomodulin in vascular smooth muscle cells--a gene therapy concept to inhibit recurrent stenosis]

scientific article published on 01 March 2004

[Non-enzymatic glycation and oxidative stress in chronic illnesses and diabetes mellitus]

scientific article published on 01 January 1999

[Regulation of the endothelium by TNF]

scientific article published on 01 January 1991

[Role of the innate immune response in sepsis]

scientific article published on 01 January 2004

[The unsolved problem of diabetes mellitus type 2 and associated complications].

scientific article published in May 2009

alpha-Tocopherol induces leptin expression in healthy individuals and in vitro

scientific article published on July 1999

c-Fos-driven transcriptional activation of transforming growth factor β-1: inhibition of high glucose-induced promoter activity by thiazolidinediones ⬇️

scientific article published on May 2, 2003

daf-16/FOXO and glod-4/glyoxalase-1 are required for the life-prolonging effect of human insulin under high glucose conditions in Caenorhabditis elegans

scientific article

p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth

scientific journal article

sRAGE and esRAGE are not associated with peripheral or autonomic neuropathy in type 2 diabetes

scientific article published on 28 November 2007

sRAGE is elevated in septic patients and associated with patients outcome

scientific article published on 22 August 2007

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