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List of works by Peter Scheurich

A TNF receptor 2 selective agonist rescues human neurons from oxidative stress-induced cell death

scientific article

A humanized tumor necrosis factor receptor 1 (TNFR1)-specific antagonistic antibody for selective inhibition of tumor necrosis factor (TNF) action

scientific article published on 01 April 2008

A maximum likelihood estimator for parameter distributions in heterogeneous cell populations

article by Jan Hasenauer et al published May 2010 in Procedia Computer Science

A permissive role for tumor necrosis factor in vascular endothelial growth factor-induced vascular permeability.

scientific article

A single-chain TNF receptor antagonist is an effective inhibitor of TNF mediated cytotoxicity.

scientific article published on February 1995

A visual analytics approach for models of heterogeneous cell populations

scientific article

ATROSAB, a humanized antagonistic anti-tumor necrosis factor receptor one-specific antibody ⬇️

scientific article published on November 1, 2010

An anti-TNFR1 scFv-HSA fusion protein as selective antagonist of TNF action

scientific article published on 4 September 2013

Analysis of heterogeneous cell populations: A density-based modeling and identification framework

article

Analysis of interleukin 2 receptor sites on activated T cells

scientific article published on 01 May 1983

Analysis of lymphokine producing T helper cells at the clonal level

scientific article published on 01 May 1983

Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity

scientific article

Antagonistic control of tumor necrosis factor receptors by protein kinases A and C. Enhancement of TNF receptor synthesis by protein kinase A and transmodulation of receptors by protein kinase C.

scientific article published on September 1989

Antagonists of TNF action: clinical experience and new developments ⬇️

scientific article published on March 1, 2009

Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8

scientific article published on 01 July 2002

Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps.

scientific article

Biological effects of gamma-interferon on human tumor cells: quantity and affinity of cell membrane receptors for gamma-IFN in relation to growth inhibition and induction of HLA-DR expression

scientific article published in July 1985

Bistability analyses of a caspase activation model for receptor-induced apoptosis

scientific article published on 18 June 2004

Both tumor necrosis factor receptors, TNFR60 and TNFR80, are involved in signaling endothelial tissue factor expression by juxtacrine tumor necrosis factor alpha

scientific article published on 01 September 1995

Caspase-mediated cleavage converts the tumor necrosis factor (TNF) receptor-associated factor (TRAF)-1 from a selective modulator of TNF receptor signaling to a general inhibitor of NF-kappaB activation

scientific article published on 22 April 2003

Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization

scientific article

Coexpression of the human TNF receptors TR60 and TR80 in insect cells: analysis of receptor complex formation

scientific article published on October 1994

Conference

scientific article published on 01 September 1998

Continuous autotropic signaling by membrane-expressed tumor necrosis factor

scientific article published on 01 June 1999

Control of receptor-induced signaling complex formation by the kinetics of ligand/receptor interaction

scientific article published on 4 September 2002

Critical involvement of transmembrane tumor necrosis factor-alpha in endothelial programmed cell death mediated by ionizing radiation and bacterial endotoxin

scientific article published in December 1995

Death wins against life in a spatially extended model of the caspase-3/8 feedback loop

scientific article published on 21 January 2012

Density-based modeling and identification of biochemical networks in cell populations

Development of resistance to tumour necrosis factor (TNF alpha) in KYM-1 cells involves both TNF receptors

scientific article published on November 1993

Differential activation of TRAIL-R1 and -2 by soluble and membrane TRAIL allows selective surface antigen-directed activation of TRAIL-R2 by a soluble TRAIL derivative

scientific article published on 01 July 2001

Differential gamma-interferon response of human colon carcinoma cells: inhibition of proliferation and modulation of immunogenicity as independent effects of gamma-interferon on tumor cell growth

scientific article published on 01 August 1985

Dissection of the proliferative and differentiative signals controlling murine cytotoxic T lymphocyte responses

scientific article

Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes

scientific article published on 24 April 2014

Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

scientific article published in January 1998

Downregulation of tumor necrosis factor (TNF) sensitivity via modulation of TNF binding capacity by protein kinase C activators

scientific article published on December 1987

Dual function of cysteine rich domain (CRD) 1 of TNF receptor type 1: conformational stabilization of CRD2 and control of receptor responsiveness

scientific article published in March 2010

Early events during primary activation of T cells: antigen receptor cross-linking and interleukin 1 initiate proliferative response of human T cells

scientific article published on 01 November 1985

Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis

scientific article published on 8 July 2002

Enhanced MYCN oncogene expression in human neuroblastoma cells results in increased susceptibility to growth inhibition by TNF alpha

scientific article published in August 1990

Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site

scientific article published on 01 March 1997

Evidence that tumor necrosis factor alpha (TNF)-induced activation of neutrophil respiratory burst on biologic surfaces is mediated by the p55 TNF receptor

scientific article published on 01 July 1994

Expression of complete human IFN-gamma receptor and its extracellular domain in insect cells: purification and characterization of the recombinant proteins.

scientific article published on April 1994

Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway

scientific article published on 30 May 2001

Fluorescence correlation spectroscopy reveals topological segregation of the two tumor necrosis factor membrane receptors

scientific article published on 23 February 2010

Global Uncertainty Analysis for a Model of TNF-Induced NF-κB Signalling

Glycosylation of the human interferon-gamma receptor. N-linked carbohydrates contribute to structural heterogeneity and are required for ligand binding

scientific article published on January 1990

Heterogeneity reduces sensitivity of cell death for TNF-stimuli

scientific article

High affinity human IFN-gamma-binding capacity is encoded by a single receptor gene located in proximity to c-ros on human chromosome region 6q16 to 6q22

scientific article published on 01 August 1988

IFN-gamma receptors on human tumor cells: relationship between receptor ligand interactions and induction of IFN-gamma response

scientific article published on 01 September 1986

Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses

scientific article published on October 1990

Identification of a TRAF (TNF receptor-associated factor) gene in Caenorhabditis elegans

scientific article published on 01 December 1998

Identification of models of heterogeneous cell populations from population snapshot data

scientific article

Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses

scientific article published on 01 March 1987

Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF.

scientific article

Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

scientific article (publication date: 11 August 2000)

Intracellular localization and transcriptional regulation of tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4)

scientific article (publication date: October 2002)

Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway

scientific article published on 31 August 2010

Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system

scientific article published in October 2004

Mechanisms of TNF resistance: identification of membrane phosphoproteins associated with a dominant resistant phenotype in lymphoid-myeloid somatic cell hybrids.

scientific article

Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells

scientific article published on January 1997

Molecular Cloning and Expression of Human and Rat Tumor Necrosis Factor Receptor Chain (p60) and Its Soluble Derivative, Tumor Necrosis Factor-Binding Protein ⬇️

scientific article published on December 1, 1990

Monovalent TNF receptor 1-selective antibody with improved affinity and neutralizing activity

scientific article published on 02 October 2018

Murine T cell subsets and interleukins: relationships between cytotoxic T cells, helper T cells and accessory cells

scientific article published on October 1, 1982

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

scientific article published on June 2001

NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP.

scientific article published on August 2004

Nanoscale arrangement of apoptotic ligands reveals a demand for a minimal lateral distance for efficient death receptor activation

scientific article

Nanotube Action between Human Mesothelial Cells Reveals Novel Aspects of Inflammatory Responses ⬇️

scientific article published on December 27, 2011

Non-apoptotic Fas signaling.

scientific article

Noncytocidal mechanisms of action of tumor necrosis factor-alpha on human tumor cells: enhancement of HLA gene expression synergistic with interferon-gamma.

scientific article

ON/OFF and beyond--a boolean model of apoptosis

scientific article

Oncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis

scientific article

Organization of the human tumour necrosis factor receptor-associated factor 1 (TRAF1) gene and mapping to chromosome 9q33–34 ⬇️

scientific article published on August 11, 1997

Postnatal development of functional T cell subsets in the mouse: a frequency analysis of mitogen reactive precursors of proliferating, of cytotoxic and of IL 2 producing T cells

scientific article published on 01 July 1985

Quantification and characterization of high-affinity membrane receptors for tumor necrosis factor on human leukemic cell lines

scientific article published on 01 July 1986

Quantitation and characterization of gamma-interferon receptors on human tumor cells

scientific article published on 01 October 1986

Quantitative representation of all T cells committed to develop into cytotoxic effector cells and/or interleukin 2 activity-producing helper cells within murine T lymphocyte subsets ⬇️

scientific article published on 01 January 1984

Rapid modulation of tumor necrosis factor membrane receptors by activators of protein kinase C

scientific article published on 01 December 1986

Response to bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores

scientific article published on 2 February 2007

Reverse signaling through transmembrane TNF confers resistance to lipopolysaccharide in human monocytes and macrophages

scientific article

Role of the 75-kDa TNF receptor in TNF-induced activation of neutrophil respiratory burst

scientific article published on 01 January 1999

Segregation of APO‐1/Fas antigen‐ and tumor necrosis factor receptor‐mediated apoptosis ⬇️

scientific article published on October 1, 1994

Selective Blocking of TNF Receptor 1 Attenuates Peritoneal Dialysis Fluid Induced Inflammation of the Peritoneum in Mice

scientific article

Sensitivity analysis of programmed cell death and implications for crosstalk phenomena during Tumor Necrosis Factor stimulation

Sensitivity analysis of programmed cell death and implications for crosstalk phenomena during Tumor Necrosis Factor stimulation

Sequential therapy with recombinant interferons gamma and alpha in patients with unfavorable prognosis of chronic myelocytic leukemia: clinical responsiveness to recombinant IFN-alpha correlates with the degree of receptor down-regulation

scientific article published in February 1989

Single chain TNF derivatives with individually mutated receptor binding sites reveal differential stoichiometry of ligand receptor complex formation for TNFR1 and TNFR2

scientific article published on 04 March 2010

Single-chain TNF, a TNF derivative with enhanced stability and antitumoral activity

scientific article

Specific membrane receptors for human interferon-gamma (IFN-gamma).

scientific article

Steady state and (bi-) stability evaluation of simple protease signalling networks

scientific article published on 14 January 2007

Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

scientific article published on 20 May 2020

Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: functional analysis of the tumor necrosis factor receptors

scientific article published on 01 July 1996

T-T cell interactions during in vitro cytotoxic T cell responses. VI. The role of T cell-derived colony-stimulating factor in helper T cell activation

scientific article published on 01 February 1984

T-T cell interactions during in vitro cytotoxic T lymphocyte responses. V. Precursor frequencies and specificity of alloreactive helper T cells ⬇️

scientific article published on July 1, 1982

TNF Signaling in Peritoneal Mesothelial Cells: Pivotal Role of cFLIPL.

scientific article published on 17 January 2017

TNF receptor associated factors in cytokine signaling.

scientific article

TNF receptors TR60 and TR80 can mediate apoptosis via induction of distinct signal pathways

scientific article published on September 1994

TNF signal transduction and TNF-responsive genes

scientific article published on January 1, 1992

TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy

scientific article

TNFR1-induced activation of the classical NF-κB pathway

scientific article published on 08 February 2011

TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60

scientific article published on 01 September 1998

TR60 and TR80 tumor necrosis factor (TNF)-receptors can independently mediate cytolysis

scientific article

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

scientific article published on December 1998

TWEAK can induce cell death via endogenous TNF and TNF receptor 1.

scientific article

Targeted lipid-coated nanoparticles: delivery of tumor necrosis factor-functionalized particles to tumor cells

scientific article published on 21 March 2009

The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression

scientific article published on 30 November 2004

The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

scientific article (publication date: June 2001)

The Transmembrane Domains of TNF-Related Apoptosis-Inducing Ligand (TRAIL) Receptors 1 and 2 Co-Regulate Apoptotic Signaling Capacity ⬇️

scientific article published on August 3, 2012

The Tumor Necrosis Factor Receptor Stalk Regions Define Responsiveness to Soluble versus Membrane-Bound Ligand ⬇️

scientific article published on April 30, 2012

The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase

scientific article published on 01 July 1999

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

scientific journal article

The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation

scientific article published on 01 October 2000

The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor ⬇️

scientific article published on January 20, 1998

Tumor necrosis factor (TNF) alpha: control of TNF-sensitivity and molecular mechanisms of TNF-mediated growth inhibition

scientific article published on July 1987

Tumor necrosis factor (TNF) and phorbol ester induce TNF-related apoptosis-inducing ligand (TRAIL) under critical involvement of NF-kappa B essential modulator (NEMO)/IKKgamma

scientific article

Tumor necrosis factor (TNF) receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1

scientific article published on 01 January 1998

Tumor necrosis factor (TNF)-functionalized nanostructured particles for the stimulation of membrane TNF-specific cell responses

scientific article published on November 2005

Tumor necrosis factor and lymphotoxin gene expression in human tumor cell lines.

scientific article published in October 1988

Tumor necrosis factor enhances HLA-A,B,C and HLA-DR gene expression in human tumor cells

scientific article published on 01 February 1987

Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation

scientific article published on 13 October 2003

Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling.

scientific article

Tumor necrosis factor receptor-associated factor-1 enhances proinflammatory TNF receptor-2 signaling and modifies TNFR1-TNFR2 cooperation

scientific article published on 16 March 2009

Tumor necrosis factor signal transduction. Tissue-specific serine phosphorylation of a 26-kDa cytosolic protein.

scientific article

Tumor necrosis factor signaling.

scientific article

Tumor necrosis factor-induced changes of gene expression in U937 cells. Differentiation-dependent plasticity of the responsive state

scientific article published on 01 May 1988

Tumor necrosis factor-receptor 2 is up-regulated on lamina propria T cells in Crohn's disease and promotes experimental colitis in vivo

scientific article published on 01 November 2002

Tumour necrosis factor signal transduction

scientific article published on January 1990

p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells

scientific article published on February 2001

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