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List of works by Brett R Blackman

A new in vitro model to evaluate differential responses of endothelial cells to simulated arterial shear stress waveforms

scientific article published on 01 August 2002

An In Vitro Cynomolgus Vascular Surrogate System for Preclinical Drug Assessment and Human Translation

scientific article published on 20 August 2015

Arterial shear stress regulates endothelial cell-directed migration, polarity, and morphology in confluent monolayers

scientific article

Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation

scientific article

Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming

scientific article

Biomechanical activation of vascular endothelium as a determinant of its functional phenotype.

scholarly article

Capillary sprout endothelial cells exhibit a CD36 low phenotype: regulation by shear stress and vascular endothelial growth factor-induced mechanism for attenuating anti-proliferative thrombospondin-1 signaling

scientific article

Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis

scientific article

Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis

scientific article published on 8 December 2016

Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature.

scholarly article

Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice ⬇️

scientific article published on November 19, 2012

Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice

scientific article

Exposure of Induced Pluripotent Stem Cell-Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell-Like Phenotypes.

scientific article published on 19 June 2017

GRP78 upregulation by atheroprone shear stress via p38-, alpha2beta1-dependent mechanism in endothelial cells

scientific article

Hemodynamic Activation of β-Catenin and T-Cell-Specific Transcription Factor Signaling in Vascular Endothelium Regulates Fibronectin Expression ⬇️

scientific article published on April 28, 2011

Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro

scientific article

Hemodynamics and Mechanobiology of Endothelium

Hemodynamics associated with atrial fibrillation directly alters thrombotic potential of endothelial cells

scientific article published on 27 April 2016

Human IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow

scientific article

Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells ⬇️

scientific article published on January 1, 2013

In vitro cell shearing device to investigate the dynamic response of cells in a controlled hydrodynamic environment

scientific article published on 01 April 2000

Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype ⬇️

scientific article published on September 23, 2010

Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis

scientific article

Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis.

scientific article

Mechanical properties of the extracellular matrix alter expression of smooth muscle protein LPP and its partner palladin; relationship to early atherosclerosis and vascular injury

scientific article

Mechanisms of Amplified Arteriogenesis in Collateral Artery Segments Exposed to Reversed Flow Direction

scientific article

Mechanisms of mechanotransduction.

scientific article

Mechanosensitive endothelial gene expression profiles: scripts for the role of hemodynamics in atherogenesis?

scientific article published on 01 December 2001

Organotypic systems in drug metabolism and toxicity: challenges and opportunities ⬇️

scientific article published on May 26, 2012

PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns

scientific article

Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system

scientific article published on 6 December 2016

Selective modulation of endothelial cell [Ca2+]i response to flow by the onset rate of shear stress

scientific article published on 01 June 2000

Small molecule inducers of angiogenesis for tissue engineering

scientific article

Spatial and spectral heterogeneity of time-varying shear stress profiles in the carotid bifurcation by phase-contrast MRI.

scientific article

Three‐dimensional phase contrast angiography of the mouse aortic arch using spiral MRI ⬇️

scientific article published on June 7, 2011

Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytes

scientific article published on 25 November 2015

p21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow.

scientific article

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