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List of works by Pierre-Yves Dietrich

A multicenter phase II trial (SAKK 36/06) of single-agent everolimus (RAD001) in patients with relapsed or refractory mantle cell lymphoma

scientific article

A novel approach to characterize clonality and differentiation of human melanoma-specific T cell responses: spontaneous priming and efficient boosting by vaccination.

scientific article published in July 2006

A self-defence mechanism of astrocytes against Fas-mediated death involving interleukin-8 and CXCR2.

scientific article published in October 2002

ATIM-20. GAPVAC-101 TRIAL OF A HIGHLY PERSONALIZED PEPTIDE VACCINATION FOR PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA

Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 19 December 2018

An Experimentally Defined Hypoxia Gene Signature in Glioblastoma and Its Modulation by Metformin

scientific article published on 02 September 2020

Antigenic expression and spontaneous immune responses support the use of a selected peptide set from the IMA950 glioblastoma vaccine for immunotherapy of grade II and III glioma

scientific article published on 7 November 2017

Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma.

scientific article

Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells via aberrantly expressed vanilloid receptor-1.

scientific article published on April 2004

Arachidonylethanolamide induces apoptosis of human glioma cells through vanilloid receptor-1.

scientific article published on September 2004

B7-homolog 1 expression by human glioma: a new mechanism of immune evasion.

scientific article published on July 2005

BRAF/MEK double blockade in refractory anaplastic pleomorphic xanthoastrocytoma.

scientific article published on 24 February 2017

Brain microenvironment promotes the final functional maturation of tumor-specific effector CD8+ T cells

scientific article published on July 2007

Brain tumor immunotherapy: Illusion or hope?

scientific article published on 16 March 2017

CAR T-Cell Therapies in Glioblastoma: A First Look

scientific article published on 20 November 2017

Cell-penetrating peptides-the Swiss Army knife of cancer vaccines.

scientific article

Circulating Tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity

scientific article published on 01 March 2002

Classification of human astrocytic gliomas on the basis of gene expression: a correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes.

scientific article published on October 2003

Clinical activity of rituximab in extranodal marginal zone B-cell lymphoma of MALT type

scientific article (publication date: 15 October 2003)

Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide

scientific article published on March 2004

Complete remission with tyrosine kinase inhibitors in renal cell carcinoma

scientific article

Comprehensive metagenomic analysis of glioblastoma reveals absence of known virus despite antiviral-like type I interferon gene response

scientific article published on 8 May 2014

Cooperative expression of junctional adhesion molecule-C and -B supports growth and invasion of glioma

scientific article

Current strategies for vaccination in glioblastoma

scientific article published on 01 November 2019

Cutting edge: cross-presentation as a mechanism for efficient recruitment of tumor-specific CTL to the brain.

scientific article published in September 2003

De sérieuses préoccupations qui ne cachent pas nos espoirs

scientific article published on 01 May 2019

De vrais espoirs et de sérieuses préoccupations

Death receptors on reactive astrocytes: a key role in the fine tuning of brain inflammation?

scientific article

Decitabine Treatment of Glioma-Initiating Cells Enhances Immune Recognition and Killing

scientific article

Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans

scientific article

Delayed but Complete Response following Oral Temozolomide Treatment in Melanoma Leptomeningeal Carcinomatosis ⬇️

scientific article published on April 6, 2011

Describing adverse events in Swiss hospitalized oncology patients using the Global Trigger Tool

scientific article published on 12 May 2020

Diagnosis and treatment of follicular lymphoma: an update

scientific article published on 24 July 2018

Direct transoral approach to C2 for percutaneous vertebroplasty

scientific article published on November 2002

Distinct structural TCR repertoires in naturally occurring versus vaccine-induced CD8+ T-cell responses to the tumor-specific antigen NY-ESO-1

scientific article published on 01 May 2005

ER-mitochondria contacts control surface glycan expression and sensitivity to killer lymphocytes in glioma stem-like cells.

scientific article published on 10 March 2017

Early closure of fistula using neo-adjuvant intra-arterial chemotherapy in locally advanced anal cancer

scientific article published on 5 September 2017

Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants

scientific article published on 5 July 2016

Erratum to: MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and

article

Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex

scientific article

Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA.

scientific article published on 19 May 2004

Exemples of tumor markers and their clinical utility

scientific article published on May 22, 2013

Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy.

scientific article published on 14 March 2012

Exploratory Study of the Effect of IMA950/Poly-ICLC Vaccination on Response to Bevacizumab in Relapsing High-Grade Glioma Patients

scientific article published on 02 April 2019

Extrachromosomal driver mutations in glioblastoma and low-grade glioma

scientific article

Fine-needle aspiration biopsy for the diagnosis of metastatic type B thymoma to lymph nodes: a case report

scientific article published on 01 March 2013

First report of clinical responses to immunotherapy in 3 relapsing cases of chordoma after failure of standard therapies.

scientific article published on 21 June 2017

Gastrointestinal relapse of multiple myeloma and sustained response to lenalidomide: a case report.

scientific article published on 19 March 2011

Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma

scientific article

High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma

scientific article published in September 2004

Homing phenotypes of tumor-specific CD8 T cells are predetermined at the tumor site by crosspresenting APCs.

scientific article published on February 2005

Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues

scientific article published in March 2004

Hypoxia and antitumor CD8+ T cells: An incompatible alliance?

scientific article published on 9 September 2016

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

scientific article published on 02 August 2018

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

scientific article published on 01 June 2019

Identification of a novel population of highly cytotoxic c-Met-expressing CD8+ T lymphocytes.

scientific article published on 27 July 2017

Immune infiltration of spontaneous mouse astrocytomas is dominated by immunosuppressive cells from early stages of tumor development

scientific article published on 25 May 2010

Immunologic Clearance of a BK Virus-associated Metastatic Renal Allograft Carcinoma

scientific article published on 21 February 2020

Immunotherapy for brain tumors: obstacles and perspectives

scientific article published in April 2016

Immunotherapy for glioma: from illusion to realistic prospects?

scientific article published on January 2014

Immunotherapy of Brain Tumors.

scientific article published on 04 September 2015

Immunotherapy of Malignant Tumors in the Brain: How Different from Other Sites?

scientific article

Immunotherapy of metastatic melanoma by intratumoral injections of Vero cells producing human IL-2: phase II randomized study comparing two dose levels

scientific article published on March 2002

Impact of Radiochemotherapy on Immune Cell Subtypes in High-Grade Glioma Patients

scientific article published on 14 February 2020

Inflammation and lymphocyte infiltration are associated with shorter survival in patients with high-grade glioma

scientific article published on 21 June 2020

Late is usually too late, but too much is too much

scientific article published on May 22, 2013

Limits of CD133 as a marker of glioma self-renewing cells

scientific article published in July 2009

Long-term follow-up of patients with follicular lymphoma receiving single-agent rituximab at two different schedules in trial SAKK 35/98

scientific article

Low 5-year cumulative incidence of post-transplant lymphoproliferative disorders after solid organ transplantation in Switzerland

scientific article published on 08 March 2018

L’accès à l’innovation

scientific article published in May 2017

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

scientific article

Marker-independent identification of glioma-initiating cells

scientific article published on 21 February 2010

Maximizing output from current glioma vaccine trials to construct robust next-generation immunotherapies.

scientific article published in November 2013

Monovoxel 1H magnetic resonance spectroscopy in the progression of gliomas.

scientific article

Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival

article

Natural HLA class I ligands from glioblastoma: extending the options for immunotherapy ⬇️

scientific article published on December 23, 2012

Novel Cell-Penetrating Peptide-Based Vaccine Induces Robust CD4+ and CD8+ T Cell-Mediated Antitumor Immunity

scientific article published on 26 June 2015

Onco-sexologie : un regard au cœur des patients

Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment

scientific article published on 05 October 2020

Outcome of patients with nonmetastatic muscle-invasive bladder cancer not undergoing cystectomy after treatment with noncisplatin-based chemotherapy and/or radiotherapy: a retrospective analysis

scientific article published on 22 March 2016

Patient-Derived In Vitro Models for Drug Discovery in Colorectal Carcinoma

scientific article published on 31 May 2020

Pelvic osteoplasty in osteolytic metastases: technical approach under fluoroscopic guidance and early clinical results

scientific article

Peptides as cancer vaccines

scientific article published on 01 March 2019

Percutaneous Vertebroplasty in Metastatic Disease: Transpedicular Access and Treatment of Lysed Pedicles—Initial Experience ⬇️

scientific article published on November 1, 2003

Percutaneous cementoplasty in multiple myeloma: a valuable adjunct for pain control and ambulation maintenance

scientific article published on 25 October 2007

Percutaneous vertebroplasty in octogenarians: results and follow-up

scientific article published on December 2005

Peripheral tolerance limits CNS accumulation of CD8 T cells specific for an antigen shared by tumor cells and normal astrocytes.

scientific article

Phase 2 trial of single-agent everolimus in chemotherapy-naive patients with castration-resistant prostate cancer (SAKK 08/08).

scientific article

Phase I/II trial testing safety and immunogenicity of the multipeptide IMA950/poly-ICLC vaccine in newly diagnosed adult malignant astrocytoma patients

scientific article published on 01 July 2019

Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma

scientific article

Phenotypic switch of CD8(+) T cells reactivated under hypoxia toward IL-10 secreting, poorly proliferative effector cells

scientific article published on May 2015

Plasmablastic lymphoma clinically presenting in the urinary tract.

scientific article published on 29 April 2011

Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen.

scientific article

Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide

scientific article

Prophylactic Cranial Irradiation in Stage III Non-Small-Cell Lung Cancer: Overall Survival Should Not Necessarily Be the Final End Point

article

Prospective validation in epithelial tumors of a gene expression predictor of liver metastasis derived from uveal melanoma

scientific article published on 20 November 2019

Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 01 February 2019

Radicular pain after vertebroplasty: compression or irritation of the nerve root? Initial experience with the "cooling system".

scientific article

Radioimmunotherapy combined with maintenance anti-CD20 antibody may trigger long-term protective T cell immunity in follicular lymphoma patients.

scientific article

Recurrent multiple CNS hemangioblastomas with VHL disease treated with pazopanib: a case report and literature review

scientific article

Resources-Stratified Guidelines for Classical Hodgkin Lymphoma

scientific article published on 09 March 2020

Responsiveness to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade in SB28 and GL261 mouse glioma models

scientific article published on 05 September 2018

Retraction Note to: Retraction: Marker-independent identification of glioma-initiating cells

article

Sister cytotoxic CD8+ T cell clones differing in natural killer inhibitory receptor expression in human astrocytoma.

scientific article published in April 2002

Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma

scientific article

Survivin in brain tumors: an attractive target for immunotherapy

scientific article published on August 2003

Synergy between CD8 T cells and Th1 or Th2 polarised CD4 T cells for adoptive immunotherapy of brain tumours

scientific article

T-cell immune responses in the brain and their relevance for cerebral malignancies

scientific article published on 01 May 2003

T-cell immunotherapy for malignant glioma: toward a combined approach.

scientific article

The relationship between brain tumor cell invasion of engineered neural tissues and in vivo features of glioblastoma ⬇️

scientific article published on July 27, 2013

Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors

scientific article published on 12 October 2006

Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells

scientific article

Une période de craintes et de défis : vers un monde meilleur ?

scientific article published on 01 May 2020

Upfront targeted therapy for symptomatic melanoma brain metastases: paradigm changing?

scientific article

Vaccination of melanoma patients with Melan-A/Mart-1 peptide and Klebsiella outer membrane protein p40 as an adjuvant

scientific article published in October 2009

Vaccination with a Melan-A peptide selects an oligoclonal T cell population with increased functional avidity and tumor reactivity

scientific article published on 01 April 2002

Withdrawal: Identification of tumor antigens among the HLA peptidomes of glioblastoma tumors and plasma

scientific article published on 01 June 2019

[Cancer and sexual medicine: a hand to the human]

article by Marie-Laure Amram et al published 1 March 2018 in Revue médicale suisse

[Integration of nutritional care into cancer treatment: need for improvement]

scientific article published on 01 November 2011

[Not available, cope with it: an unacceptable scandal]

scientific article published on 01 May 2012

[Oncology: navigating the COVID-19 Pandemic and Steer the Course]

scientific article published on 01 April 2020

[Opening of the Geneva University Hospital Prostate Cancer Center]

[The care of the sexuality among oncologic patients - A research project within the University hospitals of Geneva]

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