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List of works by John Freedman

A Preliminary Study of Platelet Activation After Embolization of Marrow Contents ⬇️

scientific article published on November 1, 2012

A cluster-randomized controlled trial of a blood conservation algorithm in patients undergoing total hip joint arthroplasty

scientific article published in May 2007

A cost-effectiveness evaluation of platelet crossmatching and HLA matching in the management of alloimmunized thrombocytopenic patients

scientific article

A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell-mediated responses that are differentially sensitive to therapy

scientific article

A novel immunosuppressive pathway involving peroxynitrite-mediated [corrected] nitration of platelet antigens within antigen-presenting cells

scientific article published on 28 June 2008

A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy

scientific article

A provincial program of blood conservation: The Ontario Transfusion Coordinators (ONTraC).

scientific article published on 4 October 2005

A rabbit model for monitoring in vivo viability of human platelet concentrates using flow cytometry

scientific article published in June 2002

A rationale for universal tranexamic acid in major joint arthroplasty: overall efficacy and impact of risk factors for transfusion

scientific article published on 01 November 2018

A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg?

scientific article

A survey of red cell use in 45 hospitals in central Ontario, Canada

scientific article published on 01 August 1996

A trypsin-like platelet protease propagates protease-activated receptor-1 cleavage and platelet activation.

scientific article published on December 1998

ABO-identical versus nonidentical platelet transfusion: a systematic review

scientific article

Abnormal cellular immune mechanisms associated with autoimmune thrombocytopenia

scientific article

About the mechanism of action of WinRho SDF

scientific article published on 01 February 2007

Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia

scientific article

Activation of caspases‐9, ‐3 and ‐8 in human platelets triggered by BH3‐only mimetic ABT‐737 and calcium ionophore A23187: caspase‐8 is activated via bypass of the death receptors ⬇️

scientific article published on October 1, 2012

Acute leukemia evolving from multiple myeloma and co-expressing myeloid and plasma cell antigens

scientific article published on July 1990

Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality

scientific article published on 15 July 2008

Allogeneic platelet transfusions prevent murine T-cell-mediated immune thrombocytopenia

scientific article

Alloimmune Thrombocytopenia

Amplified inflammatory response to sequential hemorrhage, resuscitation, and pulmonary fat embolism: an animal study

scientific article published on 01 January 2010

An example of auto-anti-A1 agglutinins

scientific article published on 01 October 1980

Analysis of platelets by flow cytometry

scientific article

Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy

scientific article

Anti-D (WinRho SD) treatment of children with chronic autoimmune thrombocytopenic purpura stimulates transient cytokine/chemokine production

scientific article

Anti-D initially stimulates an Fc-dependent leukocyte oxidative burst and subsequently suppresses erythrophagocytosis via interleukin-1 receptor antagonist

scientific article published on 26 June 2003

Antibody-mediated inhibition of the human alloimmune response to platelet transfusion in Hu-PBL-SCID mice

scientific article published on 01 March 1999

Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis

scientific article published in Nature Communications

Applications of flow cytometry in the analysis of blood leukocytes.

scientific article

Applications of flow cytometry in transfusion medicine

scientific article published on April 1995

Assessment of complement binding by anti-D and anti-M antibodies employing labelled antiglobulin antibodies

scientific article published on 01 June 1980

Autoimmune Hemolysis: A Journey through Time

scientific article

Autoimmune haemolytic anaemia with the unusual combination of both IgM and IgG autoantibodies

scientific article published on 01 January 1977

Autoimmune hemolytic anemia with concurrence of warm and cold red cell autoantibodies and a warm hemolysin

scientific article published in July 1985

Autoimmune hemolytic anemia: a history.

scientific article published in July 2000

Autoimmune pathogenesis and autoimmune hemolytic anemia

scientific article

BH3-mimetic ABT-737 induces strong mitochondrial membrane depolarization in platelets but only weakly stimulates apoptotic morphological changes, platelet shrinkage and microparticle formation.

scientific article

Binding of thrombin to the G-protein-linked receptor, and not to glycoprotein Ib, precedes thrombin-mediated platelet activation.

scientific article

Blood platelet adhesion to protein studied by on-line acoustic wave sensor

scientific article published on 01 March 2001

CD8+ T cells are predominantly protective and required for effective steroid therapy in murine models of immune thrombocytopenia

scientific article

Calpain inhibition by calpeptin does not prevent APLT activity reduction in PS-exposing platelets, but calpeptin has independent pro-apoptotic effects

scientific article published on 29 March 2010

Can antibodies with specificity for soluble antigens mimic the therapeutic effects of intravenous IgG in the treatment of autoimmune disease?

scientific article

Cellular immune dysfunction in immune thrombocytopenia (ITP).

scientific article

Cellular immune mechanisms in autoimmune thrombocytopenic purpura: An update

scientific article

Cellular immune mechanisms in chronic autoimmune thrombocytopenic purpura (ATP)

scientific article published on January 1, 1992

Changing patterns of transfusion practice in a tertiary care hospital from 1977 to 1984

scientific article published on 01 July 1986

Characterization of HIV-1-specific antibodies and HIV-1-crossreactive antibodies to platelets in HIV-1-infected haemophiliac patients

scientific article

Characterization of platelet glycoproteins and platelet/endothelial cell antibodies in patients with thrombotic thrombocytopenic purpura

scientific article

Characterization of platelet-reactive antibodies in children with varicella-associated acute immune thrombocytopenic purpura (ITP).

scientific article

Characterization of red blood cells strongly coated in vitro by C3 via the alternative pathway

scientific article published on 01 May 1980

Co-stimulation with LPS or Poly I:C markedly enhances the anti-platelet immune response and severity of fetal and neonatal alloimmune thrombocytopenia

scientific article

Coagulopathic patients with traumatic intracranial bleeding: defining the role of recombinant factor VIIa.

scientific article

Comparative study of Watson's and Cairns's trabeculectomies in a Black population with open angle glaucoma ⬇️

scientific article published on February 1, 1977

Comparison of a modified manual hexadimethrine bromide (Polybrene) and a low-ionic-strength solution antibody detection technique

scientific article published on 01 March 1985

Comparison of low-molecular-weight products following reaction of C3-C3b with C3b inactivator and with trypsin

scientific article

Comparison of platelet immunity in patients with SLE and with ITP.

scientific article

Complement in thrombotic thrombocytopenic purpura

scientific article

Concurrent and separate inside-out transition of platelet apoptosis and activation markers to the platelet surface

scientific article

Concurrent measurement of the survival of two populations of rabbit platelets labeled with either two PKH lipophilic dyes or two concentrations of biotin

scientific article published in February 2002

Control mechanisms in thrombin generation

scientific article

Coordinate activation of human platelet protease-activated receptor-1 and -4 in response to subnanomolar alpha-thrombin

scientific article

Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia

scientific article

Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity

scientific article

Differences in specificities of anti-C3d sera raised to C3d antigens prepared in different ways ⬇️

scientific article published on 01 January 1981

Directions for research in autoimmune thrombocytopenic purpura (ITP) ⬇️

scientific article published on June 1, 1998

Downregulation of the anti-HLA alloimmune response by variable region-reactive (anti-idiotypic) antibodies in leukemic patients transfused with platelet concentrates

scientific article published on 01 January 1993

Effect of complement on the viscoelastic properties of human erythrocyte membrane.

scientific article

Effect of premedication guidelines and leukoreduction on the rate of febrile nonhaemolytic platelet transfusion reactions

scientific article published on September 2000

Effects of distal embolization on the timing of platelet and inflammatory cell activation in interventional coronary no-reflow

scientific article published on 01 July 2010

Epidural anesthesia in pregnant patients with low platelet counts ⬇️

scientific article published on June 1, 1988

Epitope specificity and isotype of monoclonal anti-D antibodies dictate their ability to inhibit phagocytosis of opsonized platelets

scientific article

Evaluation of a novel transfusion algorithm employing point-of-care coagulation assays in cardiac surgery: a retrospective cohort study with interrupted time-series analysis.

scientific article published in March 2015

Experience of a network of transfusion coordinators for blood conservation (Ontario Transfusion Coordinators [ONTraC])

scientific article published on 13 November 2007

Extending storage of human platelets from 5 to 7 or 8 days does not significantly reduce their in vivo recovery and survival in a rabbit model

scientific article published on 01 July 2003

Extreme leukoreduction of major histocompatibility complex class II positive B cells enhances allogeneic platelet immunity

scientific article published on 01 January 1999

Fibrinogen and von Willebrand factor-independent platelet aggregation in vitro and in vivo

scientific article published on 05 July 2006

Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression

scientific article published on 30 March 2009

Flow cytometric analysis of platelet function in stored platelet concentrates

scientific article published on 01 April 1999

Flow cytometric analysis of platelets from childrenwith the Wiskott‐Aldrich syndrome reveals defects in platelet development, activation and structure ⬇️

scientific article published on June 1, 1997

Flow cytometric evaluation of platelet activation in blood collected into EDTA vs. Diatube-H, a sodium citrate solution supplemented with theophylline, adenosine, and dipyridamole

scientific article published on 01 September 1995

Flow cytometric parameters for characterizing platelet activation by measuring P-selectin (CD62) expression: theoretical consideration and evaluation in thrombin-treated platelet populations

scientific article published on 01 March 2000

Further Observations on the Preparation of Antiglobulin Reagents Reacting with C3d and C4d on Red Cells ⬇️

scientific article published on July 1, 1977

GPIbα is required for platelet-mediated hepatic thrombopoietin generation

scientific article published on 24 May 2018

Gamma-globulins prepared from sera of multiparous women bind anti-HLA antibodies and inhibit an established in vivo human alloimmune response.

scientific article

Guidelines on the use of intravenous immune globulin for neurologic conditions

scientific article

HLA alloimmunization against platelet transfusions: pathophysiology, significance, prevention and management ⬇️

scientific article published on April 1, 2012

Hemoglobin Optimization for Coronary Bypass: A 10-Year Canadian Multicenter Experience

scientific article published on 06 December 2018

Hemolink, an o-raffinose cross-linked haemoglobin-based oxygen carrier, does not affect activation and function of human platelets in whole blood in vitro

scientific article

Hemolytic warm IgM autoagglutinins in autoimmune hemolytic anemia

scientific article published on 01 November 1987

Higher thrombin concentrations are required to induce platelet apoptosis than to induce platelet activation.

scientific article published in March 2007

How should Canada fund the blood system? An evaluation of the chargeback proposal

scientific article

How to Avoid False-Negative and False-Positive Diagnoses of Platelet Apoptosis: Illustrative Experimental and Clinically Relevant Cases

scientific article published on 30 May 2018

ITP: an overview of the conference and future directions with an abbreviated ITP history

scientific article

IVIG induces dose-dependent amelioration of ITP in rodent models

scientific article published on 01 February 2003

IVIg inhibits reticuloendothelial system function and ameliorates murine passive-immune thrombocytopenia independent of anti-idiotype reactivity.

scientific article

IVIg-mediated amelioration of murine ITP via FcgammaRIIB is independent of SHIP1, SHP-1, and Btk activity

scientific article

Idiopathic thrombocytopenia and neutropenia in childhood

scientific article

Idiopathic thrombocytopenic purpura (ITP): a historical odyssey ⬇️

scientific article published on June 1, 1998

IgG antiplatelet immunity is dependent on an early innate natural killer cell-derived interferon-gamma response that is regulated by CD8+ T cells

scientific article

IgG-mediated immunosuppression is not dependent on erythrocyte clearance or immunological evasion: implications for the mechanism of action of anti-D in the prevention of haemolytic disease of the newborn?

scientific article published in October 2007

Immune responsiveness against allogeneic platelet transfusions is determined by the recipient's major histocompatibility complex class II phenotype

scientific article published on 01 November 2004

Immunoadsorption may provide a cost‐effective approach to management of patients with inhibitors to FVIII ⬇️

scientific article published on November 1, 2003

Immunoadsorption of factor VIII inhibitors

scientific article

Immunoglobulin G-mediated regulation of the murine immune response to transfused red blood cells occurs in the absence of active immune suppression: implications for the mechanism of action of anti-D in the prevention of haemolytic disease of the fe

scientific article published on 7 February 2008

In HPA 1a-immunized women the decrease in anti-HPA 1a antibody level during pregnancy is not associated with anti-idiotypic antibodies

scientific article published on 30 January 2009

Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia ⬇️

scientific article published on November 15, 1991

Indirect allorecognition of platelets by T helper cells during platelet transfusions correlates with anti-major histocompatibility complex antibody and cytotoxic T lymphocyte formation ⬇️

scientific article published on July 15, 1995

Induction of a secondary human anti-HLA alloimmune response in severe combined immunodeficient mice engrafted with human lymphocytes

scientific article published on 01 November 1997

Inhibition of a secondary human alloimmune response via the soluble active component of CD154 (CD40L) in severe combined immune-deficient mice engrafted with human lymphocytes.

scientific article published in August 1999

Inhibition of xenogeneic GVHD by PEN110 treatment of donor human PBMNCs

scientific article published in February 2004

Interleukins 1beta, 6, 8 and tumour necrosis factor alpha do not induce platelet activation

scientific article published on 01 October 2001

Intraarticular methylprednisolone therapy in hemophilic arthropathy ⬇️

scientific article published on January 1, 1988

Intravenous immunoglobulin ameliorates ITP via activating Fc gamma receptors on dendritic cells

scientific article

Intravenous immunoglobulin and anti-D in idiopathic thrombocytopenic purpura (ITP): mechanisms of action

scientific article

Intravenous immunoglobulin inhibits anti-glycoprotein IIb-induced platelet apoptosis in a murine model of immune thrombocytopenia

scientific article

Management of chronic immune thrombocytopenic purpura in children and adults

scientific article published on January 1, 1998

Markers of platelet apoptosis: methodology and applications ⬇️

scientific article published on May 1, 2012

Mass-scale high-throughput multiplex polymerase chain reaction for human platelet antigen single-nucleotide polymorphisms screening of apheresis platelet donors

scientific article

Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage

scientific article

Membrane-bound immunoglobulins and complement components on young and old red cells

scientific article published on 01 November 1984

Mitochondrial Inner Membrane Depolarization as a Marker of Platelet Apoptosis : Disclosure of Nonapoptotic Membrane Depolarization

scientific article published on 16 September 2016

Mitochondrial control of platelet apoptosis: effect of cyclosporin A, an inhibitor of the mitochondrial permeability transition pore

scientific article published on 23 February 2009

Mitochondrial permeability transition pore (MPTP)-dependent and -independent pathways of mitochondrial membrane depolarization, cell shrinkage and microparticle formation during platelet apoptosis

scientific article published on 10 October 2014

Monoclonal IgG can ameliorate immune thrombocytopenia in a murine model of ITP: an alternative to IVIG.

scientific article

Monoclonal antibodies that mimic the action of anti-D in the amelioration of murine ITP act by a mechanism distinct from that of IVIg

scientific article

Monoclonal antibody-mediated inhibition of the human HLA alloimmune response to platelet transfusion is antigen specific and independent of Fcgamma receptor-mediated immune suppression

scientific article published on 01 August 2000

Monoclonal platelet antigen capture assays (MAIPA) and reagents: a statement.

scientific article published in November 2007

Multimodal Patient Blood Management Program Based on a Three-pillar Strategy: A Systematic Review and Meta-analysis

scientific article published on 01 May 2019

Natural killer cell numbers and activity in patients with chronic autoimmune thrombocytopenic purpura

scientific article published on 01 February 1994

Nitric oxide insufficiency and arterial thrombosis.

scientific article published in January 2000

Optimal Conditions for the Use of Sulphydryl Compounds in Dissociating Red Cell Antibodies ⬇️

scientific article published on 01 January 1976

Parthenocissus tricuspiduta Activity Directed against Human Red Blood Cells Coated with C3b ⬇️

scientific article published on 01 September 1981

Pathologic high shear stress induces apoptosis events in human platelets

scientific article

Pentastarch instead of albumin as replacement fluid for therapeutic plasma exchange. The Canadian Apheresis Group

scientific article

Peripheral blood monocyte-derived chemokine blockade prevents murine transfusion-related acute lung injury (TRALI)

scientific article published on 17 March 2014

Permeabilization and fixation conditions for intracellular flow cytometric detection of the T-cell receptor ? chain and other intracellular proteins in lymphocyte subpopulations ⬇️

scientific article published on July 1, 1998

Persistence of phosphatidylserine exposure on activated platelets in vivo in rabbits

scientific article published on 01 August 2007

Persistence of procoagulant surface expression on activated human platelets: involvement of apoptosis and aminophospholipid translocase activity.

scientific article published on 7 December 2006

Phosphatidylserine exposure and other apoptotic-like events in Bernard-Soulier syndrome platelets

scientific article published on August 2010

Plasma cortisol suppression response in the South African black population with glaucoma ⬇️

scientific article published on November 1, 1976

Plasma fibronectin depletion enhances platelet aggregation and thrombus formation in mice lacking fibrinogen and von Willebrand factor

scientific article

Plasma fibronectin supports hemostasis and regulates thrombosis

scientific article

Plasma glutathione peroxidase deficiency and platelet insensitivity to nitric oxide in children with familial stroke

scientific article published on 01 August 1999

Plasma-derived biological medicines used to promote haemostasis

scientific article published on 01 May 2008

Plasmin accelerates platelet-dependent prothrombinase formation without activating the platelets

scientific article published on 01 February 1996

Platelet Apoptosis Can Be Triggered Bypassing the Death Receptors

scientific article published on 01 January 2019

Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo

scientific article

Platelet activation and apoptosis are different phenomena: evidence from the sequential dynamics and the magnitude of responses during platelet storage

scientific article published on 15 May 2008

Platelet activation and hypercoagulability following treatment with porcine factor VIII (HYATE:C).

scientific article

Platelet activation and von Willebrand factor binding to platelets in newborn infants with central venous lines

scientific article published on 06 December 2006

Platelet activation in warm and cold heart surgery

scientific article published in June 1995

Platelet activation induced by porcine factor VIII (Hyate:C).

scientific article

Platelet and immune responses to oral cyclic dexamethasone therapy in childhood chronic immune thrombocytopenic purpura

scientific article

Platelet and red blood cell phagocytosis kinetics are differentially controlled by phosphatase activity within mononuclear cells

scientific article published in November 2007

Platelet apoptosis in stored platelet concentrates and other models ⬇️

scientific article published on June 1, 2003

Platelet cold agglutinins: a flow cytometric analysis

scientific article

Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets

scientific article

Platelet-surface glycoproteins in healthy and preeclamptic mothers and their newborn infants

scientific article

Platelets and innate immunity

scientific article published on 18 December 2009

Platelets and the immune continuum ⬇️

scientific article published on April 1, 2011

Platelets and von Willebrand factor ⬇️

scientific article published on June 1, 2003

Platelets in hemostasis and thrombosis: role of integrins and their ligands.

scientific article

Porcine von Willebrand factor and thrombin induce the activation of c-Jun amino-terminal kinase (JNK/SAPK) whereas only thrombin induces activation of extracellular signal-related kinase 2 (ERK2) in human platelets

scientific article published on 01 June 2000

Potential Creutzfeldt-Jakob disease (CJD) exposure: to notify or not to notify

scientific article published on 01 September 1997

Preanalytical requirements for flow cytometric evaluation of platelet activation: choice of anticoagulant

scientific article published on 01 June 1999

Prenatal diagnosis of neonatal alloimmune thrombocytopenia using an allele-specific oligonucleotide probe

scientific article

Preparation of red cells coated with C4 and C3 subcomponents and production of anti-C4d and anti-C3d

scientific article published on 01 October 1976

Prevention of posttransfusion CMV in the era of universal WBC reduction: a consensus statement

scientific article

Proceedings of a consensus conference: towards an understanding of TRALI.

scientific article published in January 2005

Procoagulant surface exposure and apoptosis in rabbit platelets: association with shortened survival and steady-state senescence

scientific article published in April 2004

Prophylactic platelet transfusions: which dose is the best dose? A review of the literature

scientific article

Prospective platelet crossmatching for selection of compatible random donors ⬇️

scientific article published on 01 January 1984

Purification and characterization of human platelet glutathione-S-transferase

scientific article published on 01 June 1986

Quantification of antibodies to the C3d subcomponent of human C3 ⬇️

scientific article published on June 1, 1977

Quantification of platelet activation status by analyzing P-selectin expression

scientific article published on 01 July 2000

Random donor platelet cross-matching

scientific article published on 01 January 1986

Random donor platelet crossmatching: comparison of four platelet antibody detection methods

scientific article published on 01 May 1988

Rapid clearance of procoagulant platelet-derived microparticles from the circulation of rabbits

scientific article published on 01 July 2006

Rapid separation of CD4+ and CD19+ lymphocyte populations from human peripheral blood by a magnetic activated cell sorter (MACS)

scientific article published on 01 November 1993

Recent progress in understanding the pathogenesis of immune thrombocytopenia

scientific article

Recipient T lymphocytes modulate the severity of antibody-mediated transfusion-related acute lung injury

scientific article published on 08 July 2010

Recipient antigen-processing pathways of allogeneic platelet antigens: essential mediators of immunity

scientific article

Recipient humoral immunity against leukoreduced allogeneic platelets is suppressed by aminoguanidine, a selective inhibitor of inducible nitric oxide synthase

scientific article published on 01 October 1996

Red blood cell-bound C3d in normal subjects and in random hospital patients ⬇️

scientific article published on 01 November 1982

Red blood cell-bound C3d in selected hospital patients

scientific article published on 01 November 1982

Relative efficacy of intravenous immunoglobulin G in ameliorating thrombocytopenia induced by antiplatelet GPIIbIIIa versus GPIbalpha antibodies

scientific article

Renal sympathetic denervation for resistant hypertension: a transiently sustained placebo effect?

scientific article published on 06 November 2014

Reticulated platelet counts in the assessment of thrombocytopenic disorders ⬇️

scientific article published on June 1, 1998

Review article: risks of anemia and related management strategies: can perioperative blood management improve patient safety?

scientific article published on 25 January 2013

Role of mitochondrial membrane permeabilization and depolarization in platelet apoptosis

scientific article published on 23 August 2017

Role of platelet surface glycoprotein Ibalpha and P-selectin in the clearance of transfused platelet concentrates

scientific article published on 01 October 2004

Selective triggering of platelet apoptosis, platelet activation or both.

scientific article

Sepsis- and endotoxemia-generated cytokines do not trigger activation of human platelets

scientific article published in December 2002

Simple method for differentiating between HLA and platelet-specific antibodies by flow cytometry

scientific article published on December 1991

Stored platelet concentrates produced by the platelet-rich plasma method are more resistant to apoptosis but more sensitive to activation than are platelets prepared by the buffy-coat and apheresis methods

scientific article published on 01 July 2009

Suppressed natural killer cell activity in patients with chronic autoimmune thrombocytopenic purpura ⬇️

scientific article published on August 1, 1991

The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187.

scientific article published on December 2009

The ONTraC Ontario program in blood conservation

scientific article published on 19 December 2013

The Platelet Function Analyzer (PFA‐100®): a novel in‐vitro system for evaluation of primary haemostasis in children ⬇️

scientific article published on April 1, 1998

The activity of the von Willebrand factor cleaving protease ADAMTS-13 in newborn infants

scientific article

The cellular immunology associated with autoimmune thrombocytopenic purpura: an update.

scientific article

The effect of rabbit antithymocyte serum (RATS) and OKT3 on peripheral blood mononuclear cell subsets following renal transplantation

scientific article published on 01 December 1994

The history of idiopathic thrombocytopenic purpura (ITP).

scientific article

The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy

scientific article published on 25 January 2017

The level of matrix metalloproteinase-2 in donor plasma strongly correlates with post-transfusion recovery of stored platelet concentrates

scientific article published on 19 November 2007

The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies ⬇️

scientific article published on October 24, 2011

The relationship of von Willebrand factor binding to activated platelets from healthy neonates and adults

scientific article

The significance of complement on the red cell surface.

scientific article

The use of immunoglobulin therapy for patients undergoing solid organ transplantation: an evidence-based practice guideline.

scientific article published on January 2010

Theme issue on Ontario initiatives in blood conservation and blood management

scientific article published on 03 October 2005

Theme issue on platelets

scientific article published on 01 June 2003

Thrombin binding to platelets and their activation in plasma

scientific article published on 01 November 1994

Thrombin-triggered platelet apoptosis.

scientific article

Thymic retention of CD4+CD25+FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia

scientific article

Transfusion of IgG-opsonized foreign red blood cells mediates reduction of antigen-specific B cell priming in a murine model.

scientific article published in July 2008

Transfusion of antibody-opsonized red blood cells results in a shift in the immune response from the red blood cell to the antibody in a murine model.

scientific article published in September 2010

Transfusion--whence and why.

scientific article published on 20 December 2013

Transfusion-related acute lung injury (TRALI)

scientific article published on 01 November 2001

Transfusion-related immunomodulation by platelets is dependent on their expression of MHC Class I molecules and is independent of white cells

scientific article published on 02 June 2008

Triple heterozygosity in the integrin alphaIIb subunit in a patient with Glanzmann's thrombasthenia.

scientific article published in May 2004

Unexplained periparturient thrombocytopenia

scientific article

Unique processing pathways within recipient antigen-presenting cells determine IgG immunity against donor platelet MHC antigens

scientific article published on March 2000

Universal tranexamic acid therapy to minimize transfusion for major joint arthroplasty: a retrospective analysis of protocol implementation

scientific article published on 3 September 2015

Update on Blood Conservation for Cardiac Surgery ⬇️

scientific article published on October 14, 2011

Use of the indirect platelet radioactive antiglobulin test with anti-IgG and anti-C3 in immune and nonimmune thrombocytopenias.

scientific article

Vitronectin stabilizes thrombi and vessel occlusion but plays a dual role in platelet aggregation.

scientific article

Warm IgM anti-IT causing autoimmune haemolytic anaemia

scientific article published on 01 January 1977

White cell depletion of red cell and pooled random-donor platelet concentrates by filtration and residual lymphocyte subset analysis

scientific article published in June 1991

p38 MAPK is activated but not necessary in porcine von Willebrand factor-dependent platelet activation

scientific article published on 01 December 1999

von Willebrand factor (VWF)-dependent human platelet activation: porcine VWF utilizes different transmembrane signaling pathways than does thrombin to activate platelets, but both require protein phosphatase function

scientific article

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