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List of works by David F Ackart

2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain

scientific article published in Scientific Reports

2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability.

scientific article

A model of type 2 diabetes in the guinea pig using sequential diet-induced glucose intolerance and streptozotocin treatment

scientific article published on 12 January 2017

Activities of TMC207, rifampin, and pyrazinamide against Mycobacterium tuberculosis infection in guinea pigs

scientific article

Beijing sublineages of Mycobacterium tuberculosis differ in pathogenicity in the guinea pig.

scientific article

Cigarette smoke increases susceptibility to tuberculosis--evidence from in vivo and in vitro models

scientific article published on 28 February 2011

Copper resistance is essential for virulence of Mycobacterium tuberculosis

scientific article

Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection

scientific article published on 17 June 2020

Drug treatment combined with BCG vaccination reduces disease reactivation in guinea pigs infected with Mycobacterium tuberculosis

scientific article published on 11 January 2012

Evaluation of standard chemotherapy in the guinea pig model of tuberculosis

scientific article

Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis

scientific article

Expression of antimicrobial drug tolerance by attached communities of Mycobacterium tuberculosis

scientific article

Increased severity of tuberculosis in Guinea pigs with type 2 diabetes: a model of diabetes-tuberculosis comorbidity

scientific article

Inhibition and breaking of advanced glycation end-products (AGEs) with bis-2-aminoimidazole derivatives

scientific article published on January 2015

Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits

scientific article published on 16 October 2020

Metformin enhances protection in guinea pigs chronically infected with Mycobacterium tuberculosis

scientific article published on 01 October 2020

Non-diabetic hyperglycemia exacerbates disease severity in Mycobacterium tuberculosis infected guinea pigs

scientific article

Reversal of Mycobacterium tuberculosis phenotypic drug resistance by 2-aminoimidazole-based small molecules

scientific article

Second generation 2-aminoimidazole based advanced glycation end product inhibitors and breakers

scientific article published on 29 June 2015

Study of Real-Time Spatial and Temporal Behavior of Bacterial Biolms Using 2D Impedance Spectroscopy

scientific article published on 27 July 2020

The Discovery of 2-Aminobenzimidazoles That Sensitize Mycobacterium smegmatis and M. tuberculosis to β-Lactam Antibiotics in a Pattern Distinct from β-Lactamase Inhibitors.

scientific article

Uptake and accumulation of oxidized low-density lipoprotein during Mycobacterium tuberculosis infection in guinea pigs

scientific article