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List of works by Mahendra S Rao

A cost-effective and efficient reprogramming platform for large-scale production of integration-free human induced pluripotent stem cells in chemically defined culture

scientific article published on 11 June 2015

A focused microarray to assess dopaminergic and glial cell differentiation from fetal tissue or embryonic stem cells

scientific article published on 15 December 2005

A large-scale proteomic analysis of human embryonic stem cells

scientific article

A molecular scheme for improved characterization of human embryonic stem cell lines

scientific article published on 18 August 2006

A platform for rapid generation of single and multiplexed reporters in human iPSC lines

scientific article

A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells

scientific article published on August 2009

An efficient method for the derivation of mouse embryonic stem cells.

scientific article published on 9 December 2005

An in vitro model of human dopaminergic neurons derived from embryonic stem cells: MPP+ toxicity and GDNF neuroprotection

scientific article published on December 2006

Assessing self-renewal and differentiation in human embryonic stem cell lines

scientific article published on 17 November 2005

Autoimmune modulation of astrocyte-mediated homeostasis.

scientific article published on January 2007

BG01V: a variant human embryonic stem cell line which exhibits rapid growth after passaging and reliable dopaminergic differentiation.

scientific article

Brg1 is required for murine neural stem cell maintenance and gliogenesis

scientific journal article

Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells

scientific article

Cellular lifespan and senescence signaling in embryonic stem cells

scientific article

Characterization and in vitro differentiation potential of a new human embryonic stem cell line, ReliCellhES1.

scientific article published on March 2006

Characterization of a new NIH-registered variant human embryonic stem cell line, BG01V: a tool for human embryonic stem cell research

scientific article published on 17 November 2005

Characterization of progenitor-cell-specific genes identified by subtractive suppression hybridization

scientific article published in March 2004

Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes

scientific article published on 05 August 2015

Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies

scientific article

Comparisons between transcriptional regulation and RNA expression in human embryonic stem cell lines

scientific article published in June 2006

Conservation and variation of gene regulation in embryonic stem cells assessed by comparative genomics

scientific article published on January 2005

Creation of engineered human embryonic stem cell lines using phiC31 integrase

scientific article published on 25 October 2007

Cross-species transcriptional profiles establish a functional portrait of embryonic stem cells

scientific article published on 19 October 2006

Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation

scientific article published on 30 June 2006

Derivation and characterization of neuronal precursors and dopaminergic neurons from human embryonic stem cells in vitro

scientific article published on January 2006

Derivation of Human-Induced Pluripotent Stem Cells in Chemically Defined Medium

scientific article published on January 2017

Derivation, Characterization, and Neural Differentiation of Integration-Free Induced Pluripotent Stem Cell Lines from Parkinson's Disease Patients Carrying SNCA, LRRK2, PARK2, and GBA Mutations

scientific article

Designing, testing, and validating a focused stem cell microarray for characterization of neural stem cells and progenitor cells

scientific article

Designing, testing, and validating a microarray for stem cell characterization

scientific article published on 01 January 2006

Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications.

scientific article published on 10 June 2016

Developing safe therapies from human pluripotent stem cells

scientific article

Development of a focused microarray to assess human embryonic stem cell differentiation

scientific article published on June 2005

Development of antibodies to human embryonic stem cell antigens

scientific article

Differences between human and mouse embryonic stem cells

scientific article published in May 2004

Differential fate of multipotent and lineage-restricted neural precursors following transplantation into the adult CNS.

scientific article

Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor response

scientific article

Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease

scientific article published in December 2002

Distinguishing features of progenitor cells in the late embryonic and adult hippocampus

scientific article published in March 2003

Dopaminergic differentiation of human embryonic stem cells

scientific article

Efficient Generation of Astrocytes from Human Pluripotent Stem Cells in Defined Conditions ⬇️

scientific article published on May 1, 2013

Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions

scientific article

Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes

scientific article

Enhanced differentiation of human neural crest stem cells towards the Schwann cell lineage by aligned electrospun fiber matrix

scientific article published on 27 April 2013

Establishing standards for the characterization of human embryonic stem cell lines

scientific article published on 27 October 2005

Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes

scientific article

Evolutionarily conserved transcriptional co-expression guiding embryonic stem cell differentiation

scientific article

Expression profiling of human glial precursors

scientific article

Functional SDF1 alpha/CXCR4 signaling in the developing spinal cord

scientific article published on 01 April 2005

Gap junctional communication is required to maintain mouse cortical neural progenitor cells in a proliferative state

scientific article published in August 2004

Gene expression analysis of RNA purified from embryonic stem cells and embryoid body-derived cells using a high-throughput microarray platform

scientific article published on 01 September 2007

Gene expression in human embryonic stem cell lines: unique molecular signature

scientific article published on 30 December 2003

Gene expression profile of neuronal progenitor cells derived from hESCs: activation of chromosome 11p15.5 and comparison to human dopaminergic neurons.

scientific article

Generation and transplantation of dopaminergic neurons derived from embryonic stem cells

scientific article published on May 2007

Generation of GFP Reporter Human Induced Pluripotent Stem Cells Using AAVS1 Safe Harbor Transcription Activator-Like Effector Nuclease

scientific article

Genetic Modification in Human Pluripotent Stem Cells by Homologous Recombination and CRISPR/Cas9 System

scientific article

Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells

scientific article

Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines

scientific article published on 3 May 2006

Global Characterization and Genomic Stability of Human MultiStem, A Multipotent Adult Progenitor Cell

scientific article published in January 2009

Glutamate transporter expression and function in human glial progenitors

scientific article published on January 2004

Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes

scientific article

Hes1 but not Hes5 regulates an astrocyte versus oligodendrocyte fate choice in glial restricted precursors

scientific journal article

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress

scientific article published on 31 March 2016

Human Induced Pluripotent Stem Cell NEUROG2 Dual Knockin Reporter Lines Generated by the CRISPR/Cas9 System ⬇️

scientific article

Human Schwann Cells Retain Essential Phenotype Characteristics After Immortalization ⬇️

scientific article published on July 6, 2011

Human embryonic stem cells have enhanced repair of multiple forms of DNA damage

scientific article published on 19 June 2008

Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS

scientific article (publication date: 2011)

Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease

scientific article

Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers

scientific article published on 15 March 2018

Identification by automated screening of a small molecule that selectively eliminates neural stem cells derived from hESCs but not dopamine neurons

scientific article

Identifying and tracking neural stem cells

scientific article

Illustrating the potency of current Good Manufacturing Practice-compliant induced pluripotent stem cell lines as a source of multiple cell lineages using standardized protocols

scientific article published on 21 May 2018

Increased dentate neurogenesis after grafting of glial restricted progenitors or neural stem cells in the aging hippocampus

scientific article

Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells

scientific article published in September 2006

Isolation of neural stem and precursor cells from rodent tissue

scientific article published on 01 January 2008

Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001.

scientific article

Long-term culture of human embryonic stem cells in feeder-free conditions

scientific article published on February 2004

MPSS profiling of human embryonic stem cells

scientific article

Massively parallel signature sequencing

scientific article published in January 2006

Massively parallel signature sequencing profiling of fetal human neural precursor cells

scientific article published in April 2006

Mechanisms controlling embryonic stem cell self-renewal and differentiation

scientific journal article

Membrane properties of rat embryonic multipotent neural stem cells

scientific article published on January 2004

Microarray analysis of selected genes in neural stem and progenitor cells

scientific article published in December 2002

Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines

scientific article published on 2 April 2015

Monitoring differentiation of human embryonic stem cells using real-time PCR.

scientific article

Monitoring early differentiation events in human embryonic stem cells by massively parallel signature sequencing and expressed sequence tag scan.

scientific article published on December 2004

NTera2: a model system to study dopaminergic differentiation of human embryonic stem cells.

scientific article

Neural stem cell therapy in the aging brain: pitfalls and possibilities

scientific article published on December 2003

Neurogenesis in Talpha-1 tubulin transgenic mice during development and after injury

scientific article

Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord.

scientific article published in January 2003

Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain

scientific journal article

Olig genes are expressed in a heterogeneous population of precursor cells in the developing spinal cord

scientific article published in January 2004

Oligodendrocyte and astrocyte development in rodents: an in situ and immunohistological analysis during embryonic development

scientific article published in October 2002

Oligodendrocytes, GRPs and MNOPs

scientific article

Optimizing dopaminergic differentiation of pluripotent stem cells for the manufacture of dopaminergic neurons for transplantation ⬇️

scientific article published on May 7, 2013

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

scientific article

Properties of a fetal multipotent neural stem cell (NEP cell).

scientific article published in November 2002

Properties of four human embryonic stem cell lines maintained in a feeder-free culture system

scientific article published on February 2004

Properties of pluripotent human embryonic stem cells BG01 and BG02.

scientific article published on January 2004

Revisiting the astrocyte-oligodendrocyte relationship in the adult CNS.

scientific article published on 18 March 2007

SDF1alpha/CXCR4 signaling stimulates beta-catenin transcriptional activity in rat neural progenitors

scientific article published on 15 February 2006

Schwann cell-like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP-dependent

scientific article

Self-renewal and differentiation capabilities are variable between human embryonic stem cell lines I3, I6 and BG01V

2009 scientific article

Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling

scientific article

Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain

scientific article published in August 2005

Stage-dependent Olig2 expression in motor neurons and oligodendrocytes differentiated from embryonic stem cells

scientific article published in February 2007

Stage-specific role for shh in dopaminergic differentiation of human embryonic stem cells induced by stromal cells

scientific article published on January 2010

Stem cell and precursor cell therapy

scientific article

Stem cell myths

scientific article published on January 2008

Stem cells for the treatment of neurological disorders

scientific article published on February 2008

Stem cells: shibboleths of development, part II: Toward a functional definition

scientific article

Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells

scientific journal article

Survival and engraftment of dopaminergic neurons manufactured by a Good Manufacturing Practice-compatible process

scientific article

The microenvironment of the embryonic neural stem cell: lessons from adult niches?

scientific article published on December 2007

Toward cell replacement therapy: promises and caveats

scientific article published on November 2003

Transcription activator-like effector nuclease (TALEN)-mediated CLYBL targeting enables enhanced transgene expression and one-step generation of dual reporter human induced pluripotent stem cell (iPSC) and neural stem cell (NSC) lines

scientific article

Transcriptome Dynamics of Developing Photoreceptors in Three-Dimensional Retina Cultures Recapitulates Temporal Sequence of Human Cone and Rod Differentiation Revealing Cell Surface Markers and Gene Networks

scientific article

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation

scientific article

Transcriptome coexpression map of human embryonic stem cells

scientific article published on 2 May 2006

Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state.

scientific article published on February 2005

Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines

scientific article published on April 2016

Truncated tyrosine kinase B brain-derived neurotrophic factor receptor directs cortical neural stem cells to a glial cell fate by a novel signaling mechanism

scientific article published on 22 December 2006

Using human pluripotent stem cell-derived dopaminergic neurons to evaluate candidate Parkinson's disease therapeutic agents in MPP+ and rotenone models

scientific article published on 30 January 2013

Whole genome analysis of human neural stem cells derived from embryonic stem cells and stem and progenitor cells isolated from fetal tissue.

scientific article published in February 2007

Xeno-free defined conditions for culture of human embryonic stem cells, neural stem cells and dopaminergic neurons derived from them

scientific article

beta1 integrin maintains integrity of the embryonic neocortical stem cell niche

scientific article (publication date: August 2009)

cGMP-Manufactured Human Induced Pluripotent Stem Cells Are Available for Pre-clinical and Clinical Applications

scientific article

hESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury ⬇️

scientific article published on January 1, 2013

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