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List of works by William E Grizzle

(18)F-FDG PET/CT imaging detects therapy efficacy of anti-EMMPRIN antibody and gemcitabine in orthotopic pancreatic tumor xenografts

scientific article published on April 2012

A Phase I study of combined modality (90)Yttrium-CC49 intraperitoneal radioimmunotherapy for ovarian cancer

scientific article published on 01 September 2002

A migration signature and plasma biomarker panel for pancreatic adenocarcinoma

scientific article published on 11 November 2010

A phase I trial of the single-chain immunotoxin SGN-10 (BR96 sFv-PE40) in patients with advanced solid tumors

scientific article

A pilot study of ovarian cancer chemoprevention using medroxyprogesterone acetate in an avian model of spontaneous ovarian carcinogenesis

scientific article published in October 2002

AR negative triple negative or "quadruple negative" breast cancers in African American women have an enriched basal and immune signature.

scientific article

Acidic pH-targeted chitosan capped mesoporous silica coated gold nanorods facilitate detection of pancreatic tumors via multispectral optoacoustic tomography

scientific article

Adeno-associated virus 2-mediated antiangiogenic cancer gene therapy: long-term efficacy of a vector encoding angiostatin and endostatin over vectors encoding a single factor

scientific article published on March 2004

Adenovirus-mediated FLT1-targeted proapoptotic gene therapy of human prostate cancer

scientific article

Anti-tumor activity of TRA-8 anti-death receptor 5 (DR5) monoclonal antibody in combination with chemotherapy and radiation therapy in a cervical cancer model

scientific article published on 4 November 2005

Anti-tumor activity of the TRA-8 anti-DR5 antibody in combination with cisplatin in an ex vivo human cervical cancer model

scientific article published on 4 January 2008

Antibody responses of variable lymphocyte receptors in the lamprey.

scientific article

Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model ⬇️

scientific article published on September 1, 2003

Applying proteomic-based biomarker tools for the accurate diagnosis of pancreatic cancer

scientific article

Assessment of biomarker expression in predicting pathologic response to neoadjuvant chemotherapy in patients with locally advanced breast cancer

scientific article published on 01 September 2007

Aurora Kinase-A Inactivates DNA Damage-Induced Apoptosis and Spindle Assembly Checkpoint Response Functions of p73 ⬇️

scientific article published on February 14, 2012

BRCA1 proteins regulate growth of ovarian cancer cells by tethering Ubc9 ⬇️

scientific article published on August 20, 2012

BXD recombinant inbred mice represent a novel T cell-mediated immune response tumor model

article

Biobank: What's in a Name?

scientific article published on 01 June 2019

Biological, Medical, and Other Tissue Variables Affecting Biospecimen Utilization

scientific article published on 01 June 2019

Biomarkers and the genetics of early neoplastic lesions ⬇️

scientific article published on January 1, 2010

Biomarkers in Diagnosis of pancreatic carcinoma in fine-needle aspirates

scientific article published on 01 October 2006

Biospecimen Utilization: A Critical Challenge in Global Bioresource/Biobanking Operations

scientific article published on 01 June 2019

Breast tumor xenografts: diffusion-weighted MR imaging to assess early therapy with novel apoptosis-inducing anti-DR5 antibody

scientific article published on September 2008

CCL25 mediates migration, invasion and matrix metalloproteinase expression by breast cancer cells in a CCR9-dependent fashion ⬇️

scientific article published on February 23, 2011

CCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion

scientific article

CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion

scientific article

CCR9-CCL25 interactions promote cisplatin resistance in breast cancer cell through Akt activation in a PI3K-dependent and FAK-independent fashion ⬇️

scientific article published on May 3, 2011

COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs ⬇️

scientific article published on July 11, 2013

CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion

scientific article

CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth

scientific article published on January 2009

Celecoxib inhibits cellular growth, decreases Ki-67 expression and modifies apoptosis in ovarian cancer cell lines

scientific article published on August 2006

Cholangiocyte endothelin 1 and transforming growth factor beta1 production in rat experimental hepatopulmonary syndrome

scientific article published in August 2005

Clinical and biological significance of CXCR5 expressed by prostate cancer specimens and cell lines

scientific article published on November 2009

Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer

scientific article

Commentary on Improving Biospecimen Utilization by Classic Biobanks: Identifying Past and Minimizing Future Mistakes

scientific article published on 01 December 2018

Comparison of predicted probabilities of proportional hazards regression and linear discriminant analysis methods using a colorectal cancer molecular biomarker database.

scientific article published on 02 March 2007

Comparison of the predictive qualities of three prognostic models of colorectal cancer

scientific article published on June 2010

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Current and Emerging Clinical Applications of Multispectral Optoacoustic Tomography (MSOT) in Oncology

scientific article

DCE-MRI detects early vascular response in breast tumor xenografts following anti-DR5 therapy

scientific article

Development and progression of colorectal neoplasia ⬇️

scientific article published on January 1, 2010

Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples.

scientific article

Differential expression of breast cancer-associated genes between stage- and age-matched tumor specimens from African- and Caucasian-American Women diagnosed with breast cancer ⬇️

scientific article published on May 22, 2012

Early Therapy Evaluation of Combined Cetuximab and Irinotecan in Orthotopic Pancreatic Tumor Xenografts by Dynamic Contrast-Enhanced Magnetic Resonance Imaging

scholarly article by Hyunki Kim et al published May 2011 in Molecular imaging : official journal of the Society for Molecular Imaging

Early therapy evaluation of combined anti-death receptor 5 antibody and gemcitabine in orthotopic pancreatic tumor xenografts by diffusion-weighted magnetic resonance imaging

scientific article published on October 2008

Early therapy evaluation of combined cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging

scientific article published on June 2011

Effect of TRA-8 anti-death receptor 5 antibody in combination with chemotherapy in an ex vivo human ovarian cancer model.

scientific article published in July 2009

Effect of exercise and calorie restriction on biomarkers of aging in mice

scientific article

Effect of niclosamide on basal-like breast cancers

scientific article published on 19 February 2014

Effects of Cold Ischemia on Gene Expression: A Review and Commentary

scientific article

Effects of HIV-1 Nef, a cytotoxic viral protein, on the growth of primary colorectal cancer

scientific article published on 15 January 2005

Effects of body weight gain reduction resulting from chemopreventive agent treatment on mammary gland morphology

scientific article published in January 2002

Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents

scientific article (publication date: 2002)

Efficacy of anti-death receptor 5 (DR5) antibody (TRA-8) against primary human ovarian carcinoma using a novel ex vivo tissue slice model

scientific article published on 15 February 2007

Errata: Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples.

scientific article

Exosomes: a novel pathway of local and distant intercellular communication that facilitates the growth and metastasis of neoplastic lesions

scientific article

Experimental cancer therapy using restoration of NAD+ -linked 15-hydroxyprostaglandin dehydrogenase expression

scientific article

Expression and histopathological correlation of CCR9 and CCL25 in ovarian cancer

scientific article published on 31 May 2011

Expression of CEA, Tag-72, and Lewis-Y antigen in primary and metastatic lesions of ovarian carcinoma ⬇️

scientific article published on 01 October 2003

Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer

scientific article published on 8 June 2007

Expression of sperm protein 17 (Sp17) in ovarian cancer

scientific article

Expression of the MHC Class II Pathway in Triple-Negative Breast Cancer Tumor Cells Is Associated with a Good Prognosis and Infiltrating Lymphocytes

scientific article

Extracelluar matrix metalloproteinase as a novel target for pancreatic cancer therapy ⬇️

scientific article published on October 1, 2011

Factors Affecting the Use of Human Tissues in Biomedical Research: Implications in the Design and Operation of a Biorepository

scientific article published on January 2016

Feasibility of performing chemoprevention trials in women at elevated risk of ovarian carcinoma: initial examination of celecoxib as a chemopreventive agent

scientific article

Genomic regulation of invasion by STAT3 in triple negative breast cancer.

scientific article published on 24 December 2016

Gli1 promotes cell survival and is predictive of a poor outcome in ERalpha-negative breast cancer

scientific article

Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer

scientific article published on 03 January 2020

Hedgehog pathway expression in heterogeneous pancreatic adenocarcinoma: implications for the molecular analysis of clinically available biopsies

scientific article published in December 2007

High-grade tumor differentiation is an indicator of poor prognosis in African Americans with colonic adenocarcinomas

scientific article published on May 2005

Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells

scientific article

Hormone receptors and proliferation in breast carcinomas of equivalent histologic grades in pre- and postmenopausal women

scientific article published in March 2002

How to efficiently obtain human tissues to support specific biomedical research projects

scientific article published on 12 May 2009

Human PDE4A8, a novel brain-expressed PDE4 cAMP-specific phosphodiesterase that has undergone rapid evolutionary change

scientific article

IRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cells

scientific article

Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models in Admixed Race Populations

scientific article published on 13 May 2020

Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia

scientific article published on September 2007

Increased pulmonary vascular endothelin B receptor expression and responsiveness to endothelin-1 in cirrhotic and portal hypertensive rats: a potential mechanism in experimental hepatopulmonary syndrome

scientific article published on 01 May 2003

Inhibition of tumorigenicity by the 5'-untranslated RNA of the human c-myc P0 transcript

scientific article published on 01 August 2003

Issues in collecting, processing and storing human tissues and associated information to support biomedical research

scientific article

KISS1 over-expression suppresses metastasis of pancreatic adenocarcinoma in a xenograft mouse model ⬇️

scientific article published on September 16, 2010

L-Methionine inhibits growth of human pancreatic cancer cells

scientific article published on February 2014

LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer

scientific article

Lessons Learned During Three Decades of Operations of Two Prospective Bioresources ⬇️

scientific article published on 20 November 2018

Lung resistance-related protein (LRP) expression in malignant ascitic cells as a prognostic marker for advanced ovarian serous carcinoma.

scientific article published on 24 March 2013

Mandatory fortification with folic acid in the United States is associated with increased expression of DNA methyltransferase-1 in the cervix

scientific article

Mandatory fortification with folic acid in the United States is not associated with changes in the degree or the pattern of global DNA methylation in cells involved in cervical carcinogenesis

scientific article published on January 2006

Methionine inhibits cellular growth dependent on the p53 status of cells

scientific article published on February 2007

MicroRNA profiling of novel African American and Caucasian Prostate Cancer cell lines reveals a reciprocal regulatory relationship of miR-152 and DNA methyltranferase 1.

scientific article

Molecular staging of colorectal cancer in African-American and Caucasian patients using phenotypic expression of p53, Bcl-2, MUC-1 AND p27(kip-1).

scientific article

Mucinous expression in benign and neoplastic glandular lesions of the uterine cervix

scientific article published on 01 October 2006

Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array: Application to hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinoma

scientific article published on February 2006

Northwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES.

scientific article

Novel approaches to smoothing and comparing SELDI TOF spectra

scientific article published on January 2005

Nuclear Kaiso indicates aggressive prostate cancers and promotes migration and invasiveness of prostate cancer cells.

scientific article

Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer

scientific article published on April 2004

Organizational issues in providing high-quality human tissues and clinical information for the support of biomedical research

scientific article published on January 2010

Ovarian expression of markers associated with proliferation or apoptosis in women with diminished ovarian reserve

scientific article published on 30 May 2006

PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers

scientific article

Paradigms for primary prevention of ovarian carcinoma

scientific article

Patterns of global DNA and histone methylation appear to be similar in normal, dysplastic and neoplastic oral epithelium of humans

scientific article

Phase I study of 90Y-CC49 monoclonal antibody therapy in patients with advanced non-small cell lung cancer: effect of chelating agents and paclitaxel co-administration

scientific article

Phosphorylated LIM kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis

scientific article published on 30 August 2007

Plasma protein profiles differ between women diagnosed with cervical intraepithelial neoplasia (cin) 1 and 3.

scientific article

Polyethylene glycosylated curcumin conjugate inhibits pancreatic cancer cell growth through inactivation of Jab1.

scientific article published on 24 April 2009

Postsurgical disparity in survival between African Americans and Caucasians with colonic adenocarcinoma

scientific article published on July 2004

Prognostic significance of p27(kip-1) expression in colorectal adenocarcinomas is associated with tumor stage

scientific article published on March 2004

Prognostic significance of p53 codon 72 polymorphism differs with race in colorectal adenocarcinoma

scientific article published on April 2009

Prognostic value of mucin 4 expression in colorectal adenocarcinomas

scientific article

Pulmonary angiogenesis in a rat model of hepatopulmonary syndrome

scientific article

Quantitation of cytosine deaminase mRNA by real-time reverse transcription polymerase chain reaction: a sensitive method for assessing 5-fluorocytosine toxicity in vitro

scientific article published on February 2002

RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4

scientific article published on 26 May 2016

Receiver operating characteristic (ROC) to determine cut-off points of biomarkers in lung cancer patients

scientific article published on January 2003

Recurrence and survival predictive value of phenotypic expression of Bcl-2 varies with tumor stage of colorectal adenocarcinoma

scientific article published on January 2005

Recurrent read-through fusion transcripts in breast cancer

scientific article

S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase.

scientific article

SIRT1 is significantly elevated in mouse and human prostate cancer.

scientific article

SPARC-Independent Delivery of Nab-Paclitaxel without Depleting Tumor Stroma in Patient-Derived Pancreatic Cancer Xenografts

scientific article published on February 2016

Self-calibrated warping for mass spectra alignment.

scientific article

Smad4 inhibits tumor growth by inducing apoptosis in estrogen receptor-alpha-positive breast cancer cells

scientific article

Small molecule inhibitors of IRES-mediated translation.

scientific article published on 15 July 2015

Standards for immunohistochemical imaging: a protein reference device for biomarker quantitation

scientific article

Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling

scientific article published on 26 June 2013

Surveying the serologic proteome in a tissue-specific kras(G12D) knockin mouse model of pancreatic cancer

scientific article published on 17 November 2015

TBCRC 002: a phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormone receptor-positive and HER2-negative breast cancer

scientific article published on 18 February 2020

TBCRC 019: A Phase II Trial of Nanoparticle Albumin-Bound Paclitaxel with or without the Anti-Death Receptor 5 Monoclonal Antibody Tigatuzumab in Patients with Triple-Negative Breast Cancer.

scientific article published on 16 March 2015

TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth.

scientific article published on December 2007

Targeting Acidity in Pancreatic Adenocarcinoma: Multispectral Optoacoustic Tomography Detects pH-Low Insertion Peptide Probes In Vivo.

scientific article

Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974.

scientific article

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The Importance of Human Tissue Bioresources in Advancing Biomedical Research

scientific article published on 01 June 2019

The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype

scientific article

The Utilization of Biospecimens: Impact of the Choice of Biobanking Model

scientific article published on 01 June 2019

The biology of incipient, pre-invasive or intraepithelial neoplasia ⬇️

scientific article published on January 1, 2010

The effect of antigen retrieval on cells fixed in 10% neutral buffered formalin followed by transfer to 70% ethanol

scientific article

The efficacy of 9-cis-retinoic acid (aliretinoin) as a chemopreventive agent for cervical dysplasia: results of a randomized double-blind clinical trial

scientific article published on February 2003

The neutral red assay can be used to evaluate cell viability during autophagy or in an acidic microenvironment in vitro

scientific article published on 03 August 2020

The pattern of expression of Mn and Cu-Zn superoxide dismutase varies among squamous cell cancers of the lung, larynx, and oral cavity

scientific article

The role of endothelin-1 and the endothelin B receptor in the pathogenesis of hepatopulmonary syndrome in the rat.

scientific article published in June 2004

Transcriptional repressor Kaiso promotes epithelial to mesenchymal transition and metastasis in prostate cancer through direct regulation of miR-200c.

scientific article

Translational Dysregulation in Cancer: Molecular Insights and Potential Clinical Applications in Biomarker Development

scientific article published on 26 July 2017

Translational Pathology of Early Cancer ⬇️

scientific article published on 01 January 2010

Translational control of the undifferentiated phenotype in ER‑positive breast tumor cells: Cytoplasmic localization of ERα and impact of IRES inhibition.

scientific article published on 23 March 2018

Translational pathology of neoplasia ⬇️

scientific article published on January 1, 2010

Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation

scientific article published in November 2002

Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70.

scientific article

Tumor specific liposomes improve detection of pancreatic adenocarcinoma in vivo using optoacoustic tomography

scientific article

Validation of a robust proteomic analysis carried out on formalin-fixed paraffin-embedded tissues of the pancreas obtained from mouse and human.

scientific article

Vascular endothelial growth factor reduces tamoxifen efficacy and promotes metastatic colonization and desmoplasia in breast tumors

scientific article

miRNAs are stable in colorectal cancer archival tissue blocks

scientific article published on January 2012

p53 and erbB-2 are not associated in matched cases of primary and metastatic ovarian carcinomas

scientific article published on January 2003

the need for review and understanding of SELDI/MALDI mass spectroscopy data prior to analysis

scientific article

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