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List of works by Charles Janeway

A B-cell receptor-specific selection step governs immature to mature B cell differentiation

scholarly article

A NK1.1+ thymocyte-derived TCR beta-chain transgene promotes positive selection of thymic NK1.1+ alpha beta T cells

scientific article published on 01 September 2000

A Tale of Two T Cells ⬇️

scientific article published on 01 April 1998

A cloned, antigen-specific, Ia-restricted Lyt-1+,2- T cell with suppressive activity

scientific article published on 01 January 1983

A column method for deoxygenating human hemoglobin

scientific article published on 01 May 1966

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity ⬇️

scientific article (publication date: 24 July 1997)

A molecular map of T cell development.

scientific article published in August 1998

A novel MHC class II epitope expressed in thymic medulla but not cortex

scientific article

A novel method for concurrent visualization of immunostain under light and electron microscopy in pancreatic islets

scientific article published on 01 December 1998

A pool of central memory-like CD4 T cells contains effector memory precursors

scientific article published in March 2003

A primitive immune system

scientific article published in Nature

A role for accessibility to self-peptide-self-MHC complexes in intrathymic negative selection

scientific article published on 01 April 2001

A simple method for the radioactive iodination of CD4 molecules

scientific article published on May 1990

A trip through my life with an immunological theme

scientific article

Ability of fixed B-lymphoma cells to present foreign protein antigen fragments and allogenic MHC molecules to a cloned helper-T-cell line

scientific article published on 01 October 1987

Absence of an antigen-specific helper T cell required for the expression of the Tn 15 idiotype in mice treated with anti-μ antibody ⬇️

scientific article published on 01 February 1980

Accessories or coreceptors?

scientific article published in Nature

Activity of migration inhibitory factor in the absence of antigen

scientific article published in August 1972

Advances in paediatrics

scientific article published on 01 October 1965

Affinity-purified antigen-specific products produced by T cells share epitopes recognized by heterologous antisera raised against several different antigen-specific products from T cells ⬇️

scientific article published on 01 December 1983

Alpha(1,3)-fucosyltransferase VII and alpha(2,3)-sialyltransferase IV are up-regulated in activated CD4 T cells and maintained after their differentiation into Th1 and migration into inflammatory sites

scientific article published on 01 October 1999

Alteration at a single amino acid residue in the T cell receptor alpha chain complementarity determining region 2 changes the differentiation of naive CD4 T cells in response to antigen from T helper cell type 1 (Th1) to Th2.

scientific article

Altered positive selection due to corecognition of floppy peptide/MHC II conformers supports an integrative model of thymic selection

scholarly article

An MHC interaction site maps to the amino-terminal half of the T cell receptor α chain variable domain ⬇️

scientific article published on June 12, 1992

An analysis of the defective response of CBA/N mice to T-dependent antigens ⬇️

scientific article published on 01 October 1975

An ancient system of host defense ⬇️

scientific article published on February 1, 1998

An explanation for the protective effect of the MHC class II I–E molecule in murine diabetes

scientific article published in Nature

An external stimulus that mimics Mls locus responses

scientific article published on 01 February 1988

An islet-specific CD8+ T cell hybridoma generated from non-obese diabetic mice recognizes insulin as an autoantigen

scientific article

Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitus

scientific article

Anti-CD45 augments response of a Th2 clone to TCR cross-linking

scientific article published on 01 July 1994

Antibody-activated immunoregulatory T cells are defective in B cell deprived mice

scientific article published on 01 January 1990

Antigen presentation by B cells

scientific article published in Nature

Antigen-dependent selection of B lymphoma cells varying in Ia density by cloned antigen-specific L3T4a+ T cells: a possible in vitro model for B cell adaptive differentiation

scientific article published on 01 January 1984

Approaching the asymptote? Evolution and revolution in immunology

scientific article

Are All Baby Foods Special Dietary Foods? ⬇️

scientific article published on 01 September 1967

Are there cellular superantigens?

scientific article

Asymmetry in the recognition of antigen: self class II MHC and non-self class II MHC molecules by the same T-cell receptor

scientific article

Autocrine growth inhibition of a cloned line of helper T cells

scientific article published on March 1986

B cell-deprived mice lack functional expression of certain T suppressor cell subsets

scientific article published on 01 January 1984

Bacterial proteins that mediate the association of a defined subset of T cell receptor:CD4 complexes with class II MHC.

scientific article published on February 1990

Beneficial autoimmunity?

scientific article published on 01 September 1982

Blood and Blood Derivatives-A New Public Health Field

scientific article published on 01 January 1946

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells ⬇️

scientific article published on September 1, 1983

Both high and low avidity antibodies to the T cell receptor can have agonist or antagonist activity ⬇️

scientific article published on October 1, 1994

Breaking T cell tolerance with foreign and self co-immunogens. A study of autoimmune B and T cell epitopes of cytochrome c ⬇️

scientific article published on 01 August 1992

CD4+ T cells: specificity and function.

scientific article published on January 1988

CD62L is required on effector cells for local interactions in the CNS to cause myelin damage in experimental allergic encephalomyelitis

scientific article published on 01 March 2001

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

scientific article

CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. VII. CONCENTRATED HUMAN SERUM ALBUMIN.

scientific article

CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. XII. THE USE OF CONCENTRATED NORMAL HUMAN SERUM GAMMA GLOBULIN (HUMAN IMMUNE SERUM GLOBULIN) IN THE PREVENTION AND ATTENUATION OF MEASLES.

scientific article published on July 1944

CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. XXXVI. INACTIVATION OF THE VIRUS OF HOMOLOGOUS SERUM HEPATITIS IN SOLUTIONS OF NORMAL HUMAN SERUM ALBUMIN BY MEANS OF HEAT.

scientific article

CIITA activates the expression of MHC class II genes in mouse T cells

scientific article

Cell cooperation during in vivo anti-hapten antibody responses. V. Two synergistic Ly-1+23- helper T cells with distinctive specificities

scientific article published in April 1980

Cell cooperation during in vivo anti-hapten antibody responses. VI. Evidence for an allogeneic effect replacing one of two helper T cells

scientific article published in April 1980

Cell interactions in the immune system: the role of self recognition in the targeting of nonspecific effector molecules by helper T cells

scientific article published on 01 January 1986

Cell surface expression and alloantigenic function of a human class I MHC heavy chain gene (HLA-B7) in transgenic mice

scientific article published on 01 February 1988

Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells.

scientific article published on May 1992

Cellular cooperation during in vivo anti-hapten antibody responses. I. The effect of cell number on the response ⬇️

scientific article published on 01 April 1975

Cellular cooperation during in vivo anti-hapten antibody responses. II. The effect of in vivo and in vitro x-irradiation on T and B cells ⬇️

scientific article published on 01 April 1975

Cellular cooperation during in vivo anti-hapten antibody responses. III. The helper cell activity of activated thymocytes, of spleen cells treated with anti-theta serum, and of spleen cells from anti-thymocyte serum-treated or adult thymectomized do ⬇️

scientific article published on 01 April 1975

Characterization of H4: a mouse T lymphocyte activation molecule functionally associated with the CD3/T cell receptor

scientific article published on 01 November 1996

Characterization of a novel human surface molecule selectively expressed by mature thymocytes, activated T cells and subsets of T cell lymphomas

scientific article

Chronic treatment with rabbit anti-mouse mu-chain antibody alters the characteristic immunoglobulin heavy-chain restriction of murine suppressor T-cell factors

scientific article

Cloned helper T cells can kill B lymphoma cells in the presence of specific antigen: Ia restriction and cognatevs. noncognate interactions in cytolysis ⬇️

scientific article published on October 1, 1984

Cloning and expression of a Leishmania donovani gene instructed by a peptide isolated from major histocompatibility complex class II molecules of infected macrophages ⬇️

scientific article published on November 1, 1995

Co-receptor selection: chance or necessity?

scientific article published on 01 May 1993

Co-stimulation of murine CD4 T cell growth: cooperation between B7 and heat-stable antigen

scientific journal article

Coclustering of CD4 (L3T4) molecule with the T-cell receptor is induced by specific direct interaction of helper T cells and antigen-presenting cells

scientific article

Continuity and Change

Control of T cell responses to staphylococcal enterotoxins by stimulator cell MHC class II polymorphism.

scientific article

Cooperative interaction of B lymphocytes with antigen-specific helper T lymphocytes is MHC restricted

scientific article published in Nature

Cross-antagonism of a T cell clone expressing two distinct T cell receptors

scientific article published on 01 September 1999

Cross-linking and conformational change in T-cell receptors: role in activation and in repertoire selection

scientific article published on January 1989

Danger - pathogen on the premises! Immunological tolerance

scientific article

Deciphering the mysteries of RNA-containing lupus antigens

scientific article published on 01 July 1982

Decoding the patterns of self and nonself by the innate immune system

scientific article (publication date: 12 April 2002)

Defective antigen presentation in chronically protein-deprived mice

scientific article published on 01 April 1988

Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition

scientific article published on 01 May 1999

Development of CD8alpha/alpha and CD8alpha/beta T cells in major histocompatibility complex class I-deficient mice

scientific article

Diagnosis and treatment of antibody deficiency syndromes.

scientific article published in May 1968

Differences in the avidity of TCR interactions with a superantigenic ligand affect negative selection but do not allow positive selection ⬇️

scientific article published on 01 December 1995

Different phenotypic variants of the mouse B cell tumor A20/2J are selected by antigen- and mitogen-triggered cytotoxicity of L3T4-positive, I-A-restricted T cell clones

scientific article published on January 1986

Different superantigens interact with distinct sites in the Vbeta domain of a single T cell receptor

scientific article

Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment

scientific article published on 01 June 2000

Differential effects of antibodies to Lyt-2 and L3T4 on cytolysis by cloned, Ia-restricted T cells expressing both proteins.

scientific article published on July 1987

Differential expression of Ia glycoprotein complexes in F1 hybrid mice detected with alloreactive cloned T cell lines

scientific article published on 01 December 1982

Differential sensitivity to mutations in a single peptide by two TCRs having identical beta-chains and closely related alpha-chains

scientific article

Direct interactions between B and T lymphocytes bearing complementary receptors

scientific article

Direct physical interaction involving CD40 ligand on T cells and CD40 on B cells is required to propagate MMTV

scientific article published on 01 July 1995

Direct receptor:receptor interactions between T and B lymphocytes: idiotypic restriction in the antibody response to a cloned helper T cell receptor

scientific article published on 01 January 1987

Distinctive immunological properties of cultured murine thymic epithelial cells

scientific article published on February 1984

Diversity in T-cell receptor gamma gene usage in intestinal epithelium

scientific article

Diversity, Development, Ligands, and Probable Functions of γδ T Cells ⬇️

scientific article published on January 1, 1991

Diversity, development, ligands, and probable functions of gamma delta T cells.

scientific article

Do B cells drive the diversification of immune responses?

scientific article published on 01 April 1993

Do suppressor T cells exist? A reply

scientific article published on 01 June 1988

Dual receptor T cells extend the immune repertoire for foreign antigens.

scientific article

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

scientific article

Efficiency of antigen presentation differs in mice differing at the Mls locus ⬇️

scientific article published on 01 November 1983

Elevated temperature regulates tumor necrosis factor-mediated immune killing

scientific article

Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis.

scientific article published in September 2003

Epithelial homing of γδ T cells?

Erratum: An explanation for the protective effect of the MHC class II I–E molecule in murine diabetes

scientific article published in Nature

Evidence for Fas-dependent and Fas-independent mechanisms in the pathogenesis of experimental autoimmune encephalomyelitis

scientific article published on June 1999

Evidence for a physical association of CD4 and the CD3: α : β T-cell receptor

scientific article published in Nature

Evidence for an immunoglobulin-dependent antigen-specific helper T cell

scientific article

Exclusive Expression of MHC Class II Proteins on CD45+ Cells in Pancreatic Islets of NOD Mice ⬇️

scientific article published on 01 May 1991

Exogenously Provided Peptides of a Self-antigen Can Be Processed into Forms that Are Recognized by Self–T Cells ⬇️

scientific article published on May 4, 1998

Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice

scientific article

Experimental malaria in the CBA/N mouse ⬇️

scientific article published on December 1, 1979

Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. I. Mapping of genes for Id-460 expression to the variable region of immunoglobulin heavy-chain locus and to the variable region of immunoglobulin kappa-light-ch

scientific article

Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. II. Transient idiotypic dominance

scientific article

Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. III. Detection of Id-460 in normal serum that does not bind dinitrophenyl ⬇️

scientific article published on November 1, 1981

Expression of the co-stimulator molecule B7-1 in pancreatic beta-cells accelerates diabetes in the NOD mouse

scientific article published on 01 March 1995

Expression of the novel T cell activation molecule hpH4 in HIV-infected patients: correlation with disease status

scientific article published on 01 April 2000

Expression of transgene encoded TGF-beta in islets prevents autoimmune diabetes in NOD mice by a local mechanism.

scientific article published in August 2002

Extensive CD4 cross-linking inhibits T cell activation by anti-receptor antibody but not by antigen

scientific article published on September 1, 1992

Family Medicine — Fad or for Real? ⬇️

scientific article published on August 15, 1974

Frontiers of the immune system

scientific article published in Nature

Functional activities of antibodies against brain-associated T cell antigens. I. Induction of T cell proliferation

scientific article published on 01 July 1981

Functional and phenotypic evidence for presentation of E alpha 52-68 structurally related self-peptide(s) in I-E alpha-deficient mice

scientific article published on 01 May 2000

Functional heterogeneity among the T-derived lymphocytes of the mouse. IV. Nature of spontaneously induced suppressor cells

scientific article published on April 1975

Further observations on the Swiss type of agammaglobulinemia (alymphocytosis). The effect of syngeneic bone-marrow cells

scientific article published in January 1966

Gamma delta T cells: research on the frontlines of defence

scientific article published on 01 September 1990

Gamma delta T-cell lines isolated from intestinal epithelium respond to a B-cell lymphoma

scientific article published on 01 November 1993

Generation, propagation, and variation in cloned, antigen-specific, Ia-restricted cytolytic T-cell lines

scientific article

Goals and constraints in the education of physicians

scientific article published on 01 February 1974

Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2 ⬇️

scientific article published on 01 September 1984

HISTOLOGICAL AND SEROLOGICAL SEQUENCES IN EXPERIMENTAL HYPERSENSITIVITY.

scientific article

Hapten-specific augmentation of the anti-idiotype antibody response to hapten-myeloma protein conjugates in mice ⬇️

scientific article published on June 1, 1973

Heat-stable antigen is a costimulatory molecule for CD4 T cell growth

scientific journal article

Helper T Cells Specific for Protein Antigens: Role of Self Major Histocompatibility Complex and Immunoglobulin Gene Products ⬇️

scientific article published on 01 January 1982

Helper T cell interactions.

scientific article published on June 1979

High density insulin receptor-positive T lymphocytes from nonobese diabetic mice transfer insulitis and diabetes

scientific article published on 01 October 1996

High fives or hand clasps?

scientific article published on 01 November 1992

High levels of IL-2 alter signal transduction in cloned IL-4-producing CD4 T cells

scientific article published on 01 November 1992

How T lymphocytes recognize antigen

scientific article published on May 1, 1980

How does the immune system distinguish self from nonself?

scientific article published on 01 June 2000

How the immune system protects the host from infection ⬇️

scientific article published on November 1, 2001

How the immune system recognizes invaders.

scientific article

How the immune system works to protect the host from infection: a personal view

scientific article

Human T-cell receptor expression

scientific article published in Nature

IRAK-M is a negative regulator of Toll-like receptor signaling

scientific article

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

scientific article

Idiotypes, T-Cell Receptors, and T-B Cooperation ⬇️

scientific article published on January 1, 1980

IgG anti-DNA autoantibodies within an individual autoimmune mouse are the products of clonal selection

scientific article

Immune recognition and effector function in subsets of CD4 T cells

Immune response gene function correlates with the expression of an Ia antigen. I. Preferential association of certain Ae and E alpha chains results in a quantitative deficiency in expression of an Ae:E alpha complex

scientific article

Immune response gene function correlates with the expression of an Ia antigen. II. A quantitative deficiency in A(e):E(a), complex expression causes a corresponding defect in antigen-presenting cell function ⬇️

scientific article published on February 1, 1982

Immune responses of BALB/c mice to the idiotype of T15 and of other myeloma proteins of BALB/c origin: implications for an immune network and antibody multispecificity

scientific article

Immune serum from mice contact-sensitized with picryl chloride contains an antigen-specific T cell factor that transfers immediate cutaneous reactivity.

scientific article

Immunochemical identification of cytophilic antibody in human lymphocytes

scientific article

Immunogenicity signals 1,2,3 ... and 0.

scientific article

Immunoglobulin determinants on the lymphocytes of normal rabbits. 3. As4 and As6 determinants on individual lymphocytes and the concept of allelic exclusion

Immunoglobulin determinants on the lymphocytes of normal rabbits. I. Demonstration by the mixed antiglobulin reaction of determinants recognized by anti-gamma, anti-mu, anti-Fab and anti-allotype sera, anti-As4 and anti-As6.

scientific article

Immunologic amnesia. Study of an 11-year-old girl with recurrent severe infections associated with dysgammaglobulinemia, lymphopenia and lymphocytotoxic antibody, resulting in loss of immunologic memory

scientific article published in January 1968

Immunology at Yale

scientific article published on 01 January 1999

Immunology: improving on nature in the twenty-first century

scientific article

Immunoregulatory role of Ig isotypes. I. Induction of contrasuppressor T cells for contact sensitivity responses by antibodies of the IgM, IgG1, and IgG3 isotypes.

scientific article

Immunoregulatory role of Ig isotypes. II. Activation of cells that block induction of contact sensitivity responses by antibodies of IgG2a and IgG2b isotypes

article

Immunotherapy by peptides?

scientific article published in Nature

Implantation of a foetal thymus, restoring immunological competence in a patient with thymic aplasia (Digeorge's syndrome).

scientific article

In vitro cultivation of nonlymphoid thymic cells: morphological and immunological characterization

scientific article published on 01 February 1984

Induction of B cell costimulatory function by recombinant murine CD40 ligand

scientific article published on 01 January 1994

Induction of autoreactive B cells allows priming of autoreactive T cells ⬇️

scientific article published on June 1, 1991

Induction of receptors for interleukin 2 requires T cell Ag:Ia receptor crosslinking and interleukin 1

scientific article published on 01 January 1984

Influence of immunoglobulin-dependent T cells on antibody class switching

scientific article published on 01 August 1986

Inhibition of the responses of a cloned CD4+ T cell line to different class II major histocompatibility complex ligands by anti-CD4 and by anti-receptor Fab fragments are directly related

scientific article published on 01 January 1989

Innate Immunity: The Virtues of a Nonclonal System of Recognition ⬇️

scientific article (publication date: 31 October 1997)

Innate immune induction of the adaptive immune response

scientific article

Innate immune recognition

scientific article (publication date: 2002)

Innate immune recognition and control of adaptive immune responses ⬇️

scientific article published on 01 October 1998

Innate immune recognition: mechanisms and pathways

scientific article (publication date: February 2000)

Innate immunity

scientific article published on 01 February 1999

Innate immunity: impact on the adaptive immune response

scientific article published on February 1997

Insulin-dependent diabetes mellitus and its animal models.

scientific article

Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance

scientific article

Intestinal intraepithelial lymphocytes are a distinct set of γδ T cells

scientific article published in Nature

Intravenous dissociated gamma globulin in control of hypogammaglobulinemia.

scientific article published in July 1969

Introduction: T-cell:B-cell interaction.

scientific article published in September 1989

Introduction: The role of innate immunity in the adaptive immune response ⬇️

scientific article published on October 1, 1998

Invasive Haemophilus influenzae type b infections in vaccinated and unvaccinated children in Canada, 2001-2003.

scientific article

Inverse Ir gene control of the antibody and T cell proliferative responses to human basement membrane collagen

scientific article published on 01 November 1987

Isoform-specific associations of CD45 with accessory molecules in human T lymphocytes

scientific article published on February 1, 1992

Isolation of antigen-binding cells from unprimed mice. II. Evidence for monospecificity of antigen-binding cells ⬇️

scientific article published on April 1, 1976

It is easier for a camel to pass the needle's eye

scientific article published on 01 January 1992

John Howland Award Acceptance Address: From the American Pediatric Society, April 26,1978, New York, New York

scientific article published on December 1, 1978

Ligand thresholds at different stages of T cell development

scientific article published on 01 January 1990

Ligands for the T-cell receptor: hard times for avidity models

scientific article published on May 1995

Lipid-modified antigens. I. Specificity of guinea pig T lymphocyte responses and I-region restriction ⬇️

scientific article published on April 1, 1979

Lipoproteins take their toll on the host

scientific article published on 01 December 1999

Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells

scientific article

Low doses of interleukin 2 induce bystander cell lysis by antigen-specific CD4+ inflammatory T cell clones in short-term assay

scientific article published in September 1988

Lymphocyte activation and effector functions. Editorial overview. The role of cell surface molecules

scientific article published on 01 June 1993

Lymphocytes: the Third World

scientific article published on 01 January 1985

MHC and T cell development

scientific article

MHC recognition by clones of Mls specific T-lymphocytes ⬇️

scientific article published on 01 January 1982

MHC specificity of iIELs

scientific article

MIs: makes a little sense

scientific article published in Nature

Maintenance of TCR clonality in T cells expressing genes for two TCR heterodimers

scientific article

Medicine, medical science and health

scientific article published on March 1, 1979

Metabolism of gamma globulin fragments in normal and agammaglobulinemic persons

scientific article published in April 1968

Microbial induction of co-stimulatory activity for CD4 T-cell growth

scientific article published in April 1991

Modes of cell:cell communication in the immune system

scientific article published on 01 August 1985

Molecular associations on the T cell surface correlate with immunological memory

scientific article published in October 1990

Molecular characterization of antibodies bearing Id-460. I. The structure of two highly homologous VH genes used to produce idiotype positive immunoglobulins

scientific article published in March 1986

Molecular characterization of antibodies bearing Id-460. II. Molecular basis for Id-460 expression

scientific article

Monoclonal Antibodies Against T Cell Receptor/CD3 Complex Induce Cell Death of Th1 Clones in the Absence of Accessory Cells ⬇️

scientific article published on January 1, 1991

Monoclonal antibodies specific for Ia glycoproteins raised by immunization with activated T cells: possible role of T cellbound Ia antigens as targets of immunoregulatory T cells

scientific article published on 01 February 1984

Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation

scientific article published on 01 June 1989

Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease

scientific article (publication date: May 1981)

Monoclonal antibody against an Ir gene product? ⬇️

scientific article published on October 1, 1980

Monoclonal antibody detection of a major self peptide. MHC class II complex ⬇️

scientific article published on 01 June 1992

MyD88 Is an Adaptor Protein in the hToll/IL-1 Receptor Family Signaling Pathways ⬇️

scientific article (publication date: August 1998)

Nathalie Masse, 1919-1975 ⬇️

scientific article published on September 1, 1976

Negative selection of thymocytes expressing the D10 TCR

scientific article

Non-dinitrophenyl-binding immunoglobulin that bears a dominant idiotype (Id460) associated with antidinitrophenyl antibody is specific for an antigen on Pasteurella pneumotropica

scientific article

On the complexity of self

scientific article published in Nature

On the intrathymic intercellular transfer of self-determinants.

scientific article

On the self-referential nature of naive MHC class II-restricted T cells

scientific article published in December 2000

On the semantics of immune recognition

scientific article published on May 1996

Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells

scientific article

PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae

scientific article

Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptide

scientific article

Passive immunization against chicken pox

scientific article published on 01 May 1969

Pediatric education in the United States

scientific article published on 01 September 1966

Pediatrics and the adolescent. Presentation of the C. Anderson Aldrich Award to J. Roswell Gallagher

scientific article published in March 1973

Peptide antagonists inhibit proliferation and the production of IL-4 and/or IFN-gamma in T helper 1, T helper 2, and T helper 0 clones bearing the same TCR

scientific article published on 01 May 1997

Peptides bound to MHC

article by Charles A. Janeway et al published May 1992 in Nature

Phylogenetic perspectives in innate immunity

scientific article (publication date: 21 May 1999)

Physical association of CD4 and the T-cell receptor can be induced by anti-T-cell receptor antibodies

scientific article

Physical association of CD4 with the T cell receptor ⬇️

scientific article published on February 1, 1992

Pillars Article: Sequence Analysis of Peptides Bound to MHC Class II Molecules. Nature. 1991. 353: 622-627.

scientific article

Pillars article: approaching the asymptote? Evolution and revolution in immunology. Cold spring harb symp quant biol. 1989. 54: 1-13.

scientific article

Polymorphism of the mouse T-cell receptor AV20S1 gene

scientific article published in April 2000

Presentation of the Howland Award to Louis K. Diamond

scientific article published on October 1, 1973

Presentation of the self antigen myelin basic protein by dendritic cells leads to experimental autoimmune encephalomyelitis.

scientific article

Presidential Address to The American Association of Immunologists. The road less traveled by: the role of innate immunity in the adaptive immune response ⬇️

scientific article published on July 15, 1998

Prevention of Posttransfusion Hepatitis ⬇️

scientific article published on October 26, 1970

Prevention of diabetes in NOD mice by injection of autoreactive T-lymphocytes

scientific article published on December 1989

Progress in immunology. Syndromes of diminished resistance to infection

scientific article

Qa-2-dependent selection of CD8alpha/alpha T cell receptor alpha/beta(+) cells in murine intestinal intraepithelial lymphocytes

scientific article

Quantitative variation in la antigen expression plays a central role in immune regulation

scientific article published on April 1984

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

scientific article

Receptor-directed focusing of lymphokine release by helper T cells

scientific article published in March 1988

Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors.

scientific article

Recognition of core and flanking amino acids of MHC class II-bound peptides by the T cell receptor

scientific article

Recognition of immunoglobulin idiotypes by thymus-derived lymphocytes ⬇️

scientific article published on June 1, 1975

Recurrent infections, episodic lymphopenia and impaired cellular immunity

scientific article published on August 1969

Regulation of the immune response through idiotypic interactions

scientific article published on 01 January 1984

Regulatory responses in contact sensitivity: Afferent suppressor T cells inhibit the activation of efferent suppressor T cells ⬇️

scientific article published on February 1, 1991

Relapsing and remitting experimental autoimmune encephalomyelitis in B cell deficient mice

scientific article published in June 2000

Reminiscences of late Professor S.T. Achar

scientific article published on June 1, 1970

Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis

scientific article published in September 1996

Responses of T cells to ligands for the T-cell receptor

scientific article

Rules for peptide presentation by MHC class II molecules

scientific article published on January 1993

STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation.

scientific article

STUDIES ON INFECTIOUS MONONUCLEOSIS. II. THE RELATIONSHIP OF THE ORGANISMS OF THE GENUS LISTERELLA TO THE DISEASE, AS STUDIED BY THE AGGLUTINATION REACTION.

scientific article published on March 1941

STUDIES ON THE PLASMA PROTEINS. V. THE EFFECT OF CONCENTRATED SOLUTIONS OF HUMAN AND BOVINE SERUM ALBUMIN ON BLOOD VOLUME AFTER ACUTE BLOOD LOSS IN MAN.

scientific article

Screening for inherited diseases

scientific article published on 01 April 1971

Selected populations of alloreactive T cells contain helper T cells but lack ThId, an antigen-specific helper T cell required for dominant production of the T15 idiotype

scientific article published on March 1981

Selective Elements for the Vß Region of the T Cell Receptor: MIs and the Bacterial Toxic Mitogens

scientific article published on January 1, 1991

Selective induction of growth factor production and growth factor receptor expression by different signals to a single T cell

scientific article published on 01 November 1989

Self la-recognizing T cells undergo an ordered series of interactions with ia-bearing substrate cells of defined function during their development: A model ⬇️

scientific article published on 01 January 1984

Self peptides isolated from MHC glycoproteins of non-obese diabetic mice

scientific article published on 01 March 1994

Self superantigens?

scientific article

Self-defense: The fruit fly style ⬇️

scientific article published on January 20, 1998

Self-recognition and the biased mature repertoire in TCR beta transgenic mice: the exception that supports the rule.

scientific article published in October 2002

Sequence analysis of peptides bound to MHC class II molecules

scientific article

Signaling by a new anti-Thy 1 monoclonal antibody inhibits T cell proliferation and interferes with T-cell-mediated induction of costimulatory molecule B7-2.

scientific article

Signals and signs for lymphocyte responses

scientific article published on January 1994

Some shortcomings of medical education in a free society

scientific article published on 01 January 1967

Specific and Nonspecific Cooperation Between M-Locus-Incompatible T and B Cells During Adoptive Anti-Hapten Antibody Responses in Mice ⬇️

scientific article published on 01 January 1976

Specific loss of stimulator activity following mixed lymphocyte reactions is due to cytotoxic cells ⬇️

scientific article published on October 1, 1976

Specificity and function of T cells bearing gamma delta receptors

scientific article published in March 1988

Stimulator cell type influences the response of T cells to staphylococcal enterotoxins

scientific article published on February 1994

Studies on naturally processed peptides associated with MHC class II molecules.

scientific article

Studies with intravenous gamma globulin.

scientific article

Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides

scientific article

Superantigen-like properties of an antibody bispecific for MHC class II molecules and the V beta domain of the T cell antigen receptor

scientific article published on 01 April 1994

Suppressor T cells and immunoregulation: an overview

scientific article

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma ⬇️

scientific article published on January 1, 1993

Synthetic antigens composed exclusively of L- or D- amino acids. II. Effect of optical configuration on the metabolism and fate of synthetic polypeptide antigens in mice

scientific article published on 01 February 1968

Synthetic antigens composed exclusively of L- or D-amino acids. 3. Anamnestic response to a synthetic polypeptide composed exclusively of D-amino acids ⬇️

scientific article published on 01 November 1969

Synthetic antigens composed exclusively of L- or D-amino acids. I. Effect of optical configuration on the immunogenicity of synthetic polypeptides in mice ⬇️

scientific article published on 01 July 1967

T and B cell receptors discriminate major histocompatibility complex class II conformations influenced by the invariant chain

scientific article published on 01 August 1992

T cell adhesion to endothelial cells and extracellular matrix is modulated upon transendothelial cell migration

scientific article published in January 1997

T cell-mediated immunity in malaria. I. The Ly phenotype of T cells mediating resistance to Plasmodium yoelii.

scientific article published in July 1982

T cells from epicutaneously immunized mice are prone to T cell receptor revision

scientific article

T cells specific for hapten-modified self are precommitted for self major histocompatibility complex antigens before encounter with the hapten ⬇️

scientific article published on April 1, 1978

T cells with two functional antigen-specific receptors

scientific article

T lymphocyte responses to Mls locus antigens involve recognition of H-2 I region gene products ⬇️

scientific article published on April 28, 1977

T lymphocytes responding to Mls-locus antigens are Lyt-1+, 2− andI-A restricted ⬇️

scientific article published on January 1, 1980

T-Cell receptor idiotypes

scientific article published on 01 January 1980

T-cell development: a role for self-peptides in positive selection

scientific article

T-cell populations with different functions

scientific article published on February 13, 1975

T-cell receptors: is the repertoire inherently MHC-specific?

scientific article published on May 1997

T-cell regulation of IgA responses

scientific article published on 01 December 1983

T-cell responses to Mls and to bacterial proteins that mimic its behavior

scientific article published on February 1989

TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective

scientific article published on 01 August 1993

TCR-CD4 and TCR-TCR interactions as distinctive mechanisms for the induction of increased intracellular calcium in T-cell signalling

scientific article published on August 1993

The B cell is the initiating antigen-presenting cell in peripheral lymph nodes.

scientific article published in February 1987

The Child With Recurrent Infections ⬇️

scientific article published on 01 June 1971

The Fab fragment of a directly activating monoclonal antibody that precipitates a disulfide-linked heterodimer from a helper T cell clone blocks activation by either allogeneic Ia or antigen and self-Ia ⬇️

scientific article published on May 1, 1984

The Immunological System of the Child: Part I: Development of Immunity in the Child ⬇️

scientific article published on October 30, 2010

The Immunological System of the Child: Part II: Immunological Deficiency States ⬇️

scientific article published on October 30, 2010

The Imprint of Intrathymic Self-Peptides on the Mature T Cell Receptor Repertoire ⬇️

scientific article published on 01 October 1997

The L3T4 molecule is part of the helper T-cell antigen/Ia recognition complex

scientific article published in January 1987

The Mls locus: new clues to a lingering mystery

scientific article published on 01 May 1988

The Mls locus: past, present and future

scientific article

The PTK-STAT signaling pathway has essential roles in T-cell activation in response to antigen stimulation

scientific article

The Structure and Function of T Cell Receptor Complexes ⬇️

scientific article published on 01 October 1984

The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

scientific article published on January 1, 1992

The alpha- and beta-subunits of a murine T cell antigen/Ia receptor have a molecular weight of 31,000 in the absence of N-linked glycosylation ⬇️

scientific article published on November 1, 1984

The biologic activity of anti-T cell receptor V region monoclonal antibodies is determined by the epitope recognized.

scientific article published in February 1988

The case of the missing CD4s

scientific article published on 01 July 1992

The child with frequent infections: diagnostic considerations ⬇️

scientific article published on 01 April 1969

The co-receptor function of CD4.

scientific article published on May 1991

The co-receptor function of murine CD4.

scientific article published on June 1989

The discovery of T cell help for B cell antibody formation: a perspective from the 30th anniversary of this discovery

scientific article published in April 1999

The expression of I-Ed molecules in F1 hybrid mice detected with antigen-specific, I-Ed-restricted cloned T-cell lines ⬇️

scientific article published on 01 January 1984

The fate of a D-amino acid polypeptide [p(D-Tyr, D-Glu, D-Ala), 247] in newborn and adult mice: relationship to the induction of tolerance

scientific article published on 01 March 1969

The gamma globulins. 3. The antibody deficiency syndromes

scientific article published on 01 October 1966

The gamma globulins. 3. The antibody deficiency syndromes

scientific article published on September 1966

The gamma globulins. II. Hypergammaglobulinemia

scientific article published on 01 September 1966

The gamma globulins. II. Hypergammaglobulinemia

scientific article published on September 1966

The gamma globulins. IV. Therapeutic uses of gamma globulin

scientific article published on October 1966

The immune destruction of pancreatic β cells

scientific article published on 01 August 1985

The immune system evolved to discriminate infectious nonself from noninfectious self ⬇️

scientific article published on January 1, 1992

The immunobiology of T cell responses to Mls-locus-disparate stimulator cells. II. Effects of Mls-locus-disparate stimulator cells on cloned, protein antigen-specific, Ia-restricted T cell lines.

scientific article published on April 1985

The immunobiology of T cell responses to Mls-locus-disparate stimulator cells. III. Helper and cytolytic functions of cloned, Mls-reactive T cell lines

scientific article published on 01 January 1986

The immunobiology of the T cell response to Mls locus disparate stimulator cells

scientific article published on 01 January 1988

The immunobiology of the T cell response to Mls-locus-disparate stimulator cells. I. Unidirectionality, new strain combinations, and the role of Ia antigens.

scientific article published in April 1985

The immunosuppressive agent 15-deoxyspergualin functions by inhibiting cell cycle progression and cytokine production following naive T cell activation

scientific article published in November 2002

The influence of valence on the functional activities of monoclonal anti-L3T4 antibodies. Discrimination of signaling from other effects

scientific article published on November 1987

The mechanism of a hapten-specific helper effect in mice

scientific article published on October 1, 1973

The mouse mammary tumor virus envelope gene product is required for superantigen presentation to T cells

scientific article

The orientation of a T cell receptor to its MHC class II:peptide ligands ⬇️

scientific article published on November 1, 1997

The pathogenesis of adoptive murine autoimmune diabetes requires an interaction between alpha 4-integrins and vascular cell adhesion molecule-1.

scientific article

The priming of helper T cells.

scientific article

The response in vitro of human lymphocytes to phytohemagglutinin and to antigens after fractionation on discontinuous density gradients of albumin ⬇️

scientific article published on December 1, 1970

The role of CD4 and CD8 T cells in type I diabetes in the NOD mouse.

scientific article published on June 1997

The role of CD4 in T-cell activation: accessory molecule or co-receptor?

scientific article

The role of CD4 vs. CD8 T cells in IDDM.

scientific article

The role of Fas in autoimmune diabetes

scientific article published on 01 April 1997

The role of L3T4 in T cell activation: L3T4 may be both an Ia-binding protein and a receptor that transduces a negative signal

scientific article published on 01 January 1986

The role of immunoglobulin and B cells in T cell ontogeny and repertoire formation--a commentary

The role of lymphocyte subsets in accelerated diabetes in nonobese diabetic-rat insulin promoter-B7-1 (NOD-RIP-B7-1) mice

scientific article

The role of self-recognition in receptor repertoire development. Members of the Janeway Laboratory

scientific article

The role of the murine L3T4 molecule in T cell activation: differential effects of anti-L3T4 on activation by monoclonal anti-receptor antibodies

scientific article published on January 1987

The role of thymus-derived lymphocytes in an antibody-mediated hapten-specific helper effect ⬇️

scientific article published on January 1, 1975

The selection of self-MHC recognizing T lymphocytes: a role for idiotypes?

scientific article published on 01 October 1982

The source of early IFN-gamma that plays a role in Th1 priming

scientific article published on 01 August 2001

The specific direct interaction of helper T cells and antigen-presenting B cells

scientific article published on August 1986

The specificity and orientation of a TCR to its peptide-MHC class II ligands

scientific journal article

The specificity of T lymphocyte responses to chemically defined antigens

scientific article (publication date: 1976)

The specificity of cellular immune responses II. The structure of antigenic determinants leading to T-lymphocyte stimulation ⬇️

scientific article published on December 1, 1976

The specificity of cellular immune responses in guinea pigs. I. T cells specific for 2,4-dinitrophenyl-o-tyrosyl residues ⬇️

scientific article published on January 1, 1975

The specificity of cellular immune responses in guinea pigs. III. The precision of antigen recognition by T lymphocytes ⬇️

scientific article published on December 1, 1976

The targeting of effector molecules in the immune system

scientific article published on 01 November 1986

The use of the polymerase chain reaction to map CD4+ T cell epitopes ⬇️

scientific article published on 01 November 1991

Through a glass, darkly …

scientific article published on 01 April 1982

Thymic selection: two pathways to life and two to death

scientific article published on April 1994

Tissue-specific and cell surface expression of human major histocompatibility complex class I heavy (HLA-B7) and light (beta 2-microglobulin) chain genes in transgenic mice

scientific article

To thine own self be true...

scientific article published on 01 August 1991

Transgenes and knockout mutations in animal models of type 1 diabetes and multiple sclerosis

scientific article

Transgenic mice demonstrate that epithelial homing of gamma/delta T cells is determined by cell lineages independent of T cell receptor specificity.

scientific article

Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression ⬇️

scientific article published on October 1, 1997

Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs

scientific article published on October 1, 1992

Two Different VH Gene Products Make Up the T-Cell Receptors ⬇️

scientific article published on January 1, 1976

Two distinct antigen-specific suppressor factors induced by the oral administration of antigen

scientific article

Type 1 diabetes mellitus: an imbalance between effector and regulatory T cells?

scientific article

Unnecessary and preventable hospitalizations: report on an internal audit

scientific article published on November 1971

Use of Concentrated Human Serum gamma-Globulin in the Prevention and Attenuation of Measles

scientific article

Use of anti-idiotype immunosorbents to isolate circulating antigen-specific T cell-derived molecules from hyperimmune sera ⬇️

scientific article published on March 1, 1983

V beta selective elements: self and non-self

scientific article published on February 1991

Variability of invariant mouse CD3ε chains detected by anti-CD3 antibodies

scientific article published on 01 May 2000

Varieties of idiotype-specific helper T cells--a commentary

scientific article published on 01 January 1986

graal: a Drosophila gene coding for several mosaic serine proteases

scientific article published in October 2004

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