Search filters

List of works by Janina Ratajczak

"Small stem cells" in adult tissues: very small embryonic-like stem cells stand up!

scientific article published on January 2009

A Novel View of the Adult Stem Cell Compartment From the Perspective of a Quiescent Population of Very Small Embryonic-Like Stem Cells

scientific article published on January 2017

A Pivotal Role of Activation of Complement Cascade (CC) in Mobilization of Hematopoietic Stem/Progenitor Cells (HSPC)

scientific article published in 2008

A multi-instrumental approach to identify and purify very small embryonic like stem cells (VSELs) from adult tissues

scientific article published on 19 October 2008

A novel insight into aging: are there pluripotent very small embryonic-like stem cells (VSELs) in adult tissues overtime depleted in an Igf-1-dependent manner?

scientific article published in November 2010

A novel role of complement in mobilization: immunodeficient mice are poor granulocyte-colony stimulating factor mobilizers because they lack complement-activating immunoglobulins

scientific article published on 23 August 2007

A pivotal role of activation of complement cascade (CC) in mobilization of hematopoietic stem/progenitor cells (HSPC).

scientific article published on January 2008

ATP-Nlrp3 Inflammasome-Complement Cascade Axis in Sterile Brain Inflammation in Psychiatric Patients and its Impact on Stem Cell Trafficking

scientific article published on 01 August 2019

Abstract 4072: Embryonic rest hypothesis of cancer development revisited: functional gonadotropic hormone receptors are expressed by normal and malignant hematopoietic cells and functional erythropoietin receptor is expressed by germline-derived tumo

scientific article published in August 2015

Adult marrow-derived very small embryonic-like stem cells and tissue engineering

scientific article published on October 2007

Adult murine bone marrow-derived very small embryonic-like stem cells differentiate into the hematopoietic lineage after coculture over OP9 stromal cells

scientific article published on 27 October 2010

An emerging link in stem cell mobilization between activation of the complement cascade and the chemotactic gradient of sphingosine-1-phosphate ⬇️

scientific article published on 03 September 2012

Are bone marrow stem cells plastic or heterogenous--that is the question

scientific article published in June 2005

Beta-glucan enhances complement-mediated hematopoietic recovery after bone marrow injury

scientific article published on 15 January 2006

Bioactive Phospholipids Enhance Migration and Adhesion of Human Leukemic Cells by Inhibiting Heme Oxygenase 1 (HO-1) and Inducible Nitric Oxygenase Synthase (iNOS) in a p38 MAPK-Dependent Manner

scientific article published on 9 October 2018

Bioactive lipids S1P and C1P are prometastatic factors in human rhabdomyosarcoma, and their tissue levels increase in response to radio/chemotherapy

scientific article published on 24 April 2013

Bioactive lipids and cationic antimicrobial peptides as new potential regulators for trafficking of bone marrow-derived stem cells in patients with acute myocardial infarction

scientific article published on 19 February 2013

Biological significance of the different erythropoietic factors secreted by normal human early erythroid cells

scientific article published in May 2003

Bone Marrow - Home of Versatile Stem Cells.

scientific article published on 08 May 2008

Bone marrow as a source of circulating CXCR4+ tissue-committed stem cells

scientific article published in February 2005

Both hepatocyte growth factor (HGF) and stromal-derived factor-1 regulate the metastatic behavior of human rhabdomyosarcoma cells, but only HGF enhances their resistance to radiochemotherapy.

scientific article published in November 2003

CD133 Expression Strongly Correlates with the Phenotype of Very Small Embryonic-/Epiblast-Like Stem Cells

scientific article published on January 2013

CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion

scientific article published in March 2004

CXCR7: a new SDF-1-binding receptor in contrast to normal CD34(+) progenitors is functional and is expressed at higher level in human malignant hematopoietic cells.

scientific article published in December 2010

Cancer from the perspective of stem cells and misappropriated tissue regeneration mechanisms

scientific article published on 30 October 2018

Cardiomyocyte differentiation of bone marrow-derived Oct-4+CXCR4+SSEA-1+ very small embryonic-like stem cells

scientific article published on August 2010

Cell recovery comparison between plasma depletion/reduction- and red cell reduction-processing of umbilical cord blood

scientific article published on August 26, 2011

Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction

scientific article published on 18 November 2004

Ceramide-1-phosphate regulates migration of multipotent stromal cells and endothelial progenitor cells--implications for tissue regeneration

scientific article published in March 2013

Correction: Cancer from the perspective of stem cells and misappropriated tissue regeneration mechanisms

scientific article published on 01 April 2019

Correction: Novel evidence that extracellular nucleotides and purinergic signaling induce innate immunity-mediated mobilization of hematopoietic stem/progenitor cells

scientific article published on 01 April 2019

Emerging concept of cancer as a stem cell disorder

scientific article published in January 2006

Epiblast/germ line hypothesis of cancer development revisited: lesson from the presence of Oct-4+ cells in adult tissues

scientific article published in June 2010

Erythrocyte-derived microvesicles may transfer phosphatidylserine to the surface of nucleated cells and falsely 'mark' them as apoptotic.

scientific article published on 24 April 2009

Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow

scientific article published in August 2015

Evidence of a Pivotal Role for the Distal Part of the Complement Cascade in the Diurnal Release of Hematopoietic Stem Cells Into Peripheral Blood

scientific article published on 17 June 2015

Evidence that very small embryonic-like stem cells are mobilized into peripheral blood

scientific article published on 29 May 2008

Evidence that vitronectin is a potent migration-enhancing factor for cancer cells chaperoned by fibrinogen: a novel view of the metastasis of cancer cells to low-fibrinogen lymphatics and body cavities

scientific article published on 13 September 2016

Expression of the erythropoietin receptor by germline-derived cells - further support for a potential developmental link between the germline and hematopoiesis

scientific article published on 17 June 2014

Extracellular Microvesicles as Game Changers in Better Understanding the Complexity of Cellular Interactions-From Bench to Clinical Applications

scientific article published on 8 June 2017

Extracellular microvesicles/exosomes: discovery, disbelief, acceptance, and the future?

scientific article published on 14 September 2020

Fetal liver very small embryonic/epiblast like stem cells follow developmental migratory pathway of hematopoietic stem cells.

scientific article published in September 2009

Flt3-Ligand-Mobilized Peripheral Blood, but Not Flt3-Ligand-Expanded Bone Marrow, Facilitating Cells Promote Establishment of Chimerism and Tolerance

scientific article published in April 2006

Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1

scientific article (publication date: 15 May 2003)

Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts

scientific article published on 29 May 2015

Genome-wide analysis of murine bone marrow‑derived very small embryonic-like stem cells reveals that mitogenic growth factor signaling pathways play a crucial role in the quiescence and ageing of these cells

scientific article published on 23 May 2013

Hematopoietic Stem and Progenitor Cells (HSPCs)

scientific article published on 01 January 2019

Hematopoietic stem cells from NOD mice exhibit autonomous behavior and a competitive advantage in allogeneic recipients

scientific article published in March 2005

Hematopoietic stem/progenitor cells express several functional sex hormone receptors-novel evidence for a potential developmental link between hematopoiesis and primordial germ cells

scientific article published on 3 March 2015

Heme Oxygenase 1 (HO-1) as an Inhibitor of Trafficking of Normal and Malignant Hematopoietic Stem Cells - Clinical and Translational Implications

scientific article published on 16 November 2020

Heterogeneous populations of bone marrow stem cells--are we spotting on the same cells from the different angles?

scientific article published in January 2004

Horizontal transfer of RNA and proteins between cells by extracellular microvesicles: 14 years later

scientific article published on 4 March 2016

Human CD34+ cells isolated from bone marrow peripheral blood, cord blood and thymus secrete CCR5 binding β-chemokines

scientific article published in July 2000

Human haematopoietic stem/progenitor cells express several functional sex hormone receptors

scientific article published on 30 October 2015

Hunt for pluripotent stem cell -- regenerative medicine search for almighty cell

scientific article published on 04 February 2008

Identification of heme oxygenase 1 (HO-1) as a novel negative regulator of mobilization of hematopoietic stem/progenitor cells

scientific article published on February 2015

Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient

scientific article published on 24 August 2004

Innate Immunity as Orchestrator of Bone Marrow Homing for Hematopoietic Stem/Progenitor Cells ⬇️

scientific article published on January 1, 2013

Innate immunity orchestrates the mobilization and homing of hematopoietic stem/progenitor cells by engaging purinergic signaling-an update

scientific article published on 15 May 2020

Leukemia inhibitory factor: a newly identified metastatic factor in rhabdomyosarcomas

scientific article published on March 2007

Macrophage migration inhibitory factor is secreted by rhabdomyosarcoma cells, modulates tumor metastasis by binding to CXCR4 and CXCR7 receptors and inhibits recruitment of cancer-associated fibroblasts

scientific article published on 22 September 2010

Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer

scientific article published in February 2005

Migration of Bone Marrow and Cord Blood Mesenchymal Stem Cells In Vitro Is Regulated by Stromal-Derived Factor-1-CXCR4 and Hepatocyte Growth Factor-c-met Axes and Involves Matrix Metalloproteinases

scientific article published in May 2006

Mobilization of bone marrow-derived Oct-4+ SSEA-4+ very small embryonic-like stem cells in patients with acute myocardial infarction

scientific article published on January 2009

Mobilization of hematopoietic stem cells as a result of innate immunity-mediated sterile inflammation in the bone marrow microenvironment-the involvement of extracellular nucleotides and purinergic signaling

scientific article published on 5 March 2018

Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow

scientific article published on 6 November 2003

Modulation of the SDF-1-CXCR4 axis by the third complement component (C3)--implications for trafficking of CXCR4+ stem cells

scientific article published on August 2006

Molecular characterization of isolated from murine adult tissues very small embryonic/epiblast like stem cells (VSELs).

scientific article published on 04 June 2010

Multigene Targeting with Antisense Oligodeoxynucleotides: An Exploratory Study Using Primary Human Leukemia Cells

scientific article published in July 2005

Nlrp3 Inflammasome Signaling Regulates the Homing and Engraftment of Hematopoietic Stem Cells (HSPCs) by Enhancing Incorporation of CXCR4 Receptor into Membrane Lipid Rafts

scientific article published on 13 July 2020

Novel Therapeutic Approaches in Regenerative Medicine—Adult Tissue-Derived Very Small Embryonic-like Stem Cells and Harnessing Paracrine Signals of Adult Stem Cells

scientific article published in 2014

Novel evidence that an alternative complement cascade pathway is involved in optimal mobilization of hematopoietic stem/progenitor cells in Nlrp3 inflammasome-dependent manner

scientific article published on 26 July 2019

Novel evidence that extracellular nucleotides and purinergic signaling induce innate immunity-mediated mobilization of hematopoietic stem/progenitor cells

scientific article published in September 2018

Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells

scientific article published on 20 December 2015

Oligodeoxynucleotide-mediated inhibition of c-myb gene expression in autografted bone marrow: a pilot study

scientific article published on February 2002

Optimization of isolation and further characterization of umbilical-cord-blood-derived very small embryonic/ epiblast-like stem cells (VSELs).

scientific article published on 14 September 2009

Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas

scientific article published in December 2010

Pannexin-1 channel "fuels" by releasing ATP from bone marrow cells a state of sterile inflammation required for optimal mobilization and homing of hematopoietic stem cells

scientific article published on 12 June 2020

Paracrine Effects of Fetal Stem Cells

scientific article published in 2016

Paracrine proangiopoietic effects of human umbilical cord blood-derived purified CD133+ cells--implications for stem cell therapies in regenerative medicine

scientific article published on 5 November 2012

Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV.

scientific article published on January 2003

Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells

scientific article published in May 2002

Poor Mobilization in T-Cell-Deficient Nude Mice Is Explained by Defective Activation of Granulocytes and Monocytes

scientific article published on 18 July 2016

Potential Clinical Applications of Stem Cells in Regenerative Medicine

scientific article published on 01 January 2019

Quiescent CD34+ early erythroid progenitors are resistant to several erythropoietic 'inhibitory' cytokines; role of FLIP.

scientific article published in October 2003

RasGrf1: genomic imprinting, VSELs, and aging

scientific article published in July 2011

Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes.

scientific article published on 21 October 2008

Sphingosine-1-phosphate-mediated mobilization of hematopoietic stem/progenitor cells during intravascular hemolysis requires attenuation of SDF-1-CXCR4 retention signaling in bone marrow

scientific article published on 29 December 2013

The Emerging Link Between the Complement Cascade and Purinergic Signaling in Stress Hematopoiesis.

scientific article

The Expanding Family of Bone Marrow Homing Factors for Hematopoietic Stem Cells: Stromal Derived Factor 1 Is Not the Only Player in the Game ⬇️

scientific article published on June 4, 2012

The Inhibition of CD39 and CD73 Cell Surface Ectonucleotidases by Small Molecular Inhibitors Enhances the Mobilization of Bone Marrow Residing Stem Cells by Decreasing the Extracellular Level of Adenosine

scientific article published on 01 December 2019

The Involvment of Hematopoietic-Specific PLC -β2 in Homing and Engraftment of Hematopoietic Stem/Progenitor Cells

scientific article published on 04 October 2016

The Nlrp3 Inflammasome Orchestrates Mobilization of Bone Marrow-Residing Stem Cells into Peripheral Blood.

scientific article

The Nlrp3 inflammasome as a "rising star" in studies of normal and malignant hematopoiesis

scientific article published on 20 April 2020

The cell cycle- and insulin-signaling-inhibiting miRNA expression pattern of very small embryonic-like stem cells contributes to their quiescent state

scientific article published on 12 May 2015

The migration of bone marrow-derived non-hematopoietic tissue-committed stem cells is regulated in an SDF-1-, HGF-, and LIF-dependent manner

scientific article published on 28 March 2006

The molecular nature of very small embryonic-like stem cells in adult tissues

scientific article published in November 2014

The negative effect of prolonged somatotrophic/insulin signaling on an adult bone marrow-residing population of pluripotent very small embryonic-like stem cells (VSELs).

scientific article published on 5 January 2012

The proper criteria for identification and sorting of very small embryonic-like stem cells, and some nomenclature issues

scientific article published in April 2014

The role of innate immunity in trafficking of hematopoietic stem cells-an emerging link between activation of complement cascade and chemotactic gradients of bioactive sphingolipids

scientific article published on January 2012

The role of pluripotent embryonic-like stem cells residing in adult tissues in regeneration and longevity

scientific article published on 19 February 2011

The role of sphingosine-1 phosphate and ceramide-1 phosphate in trafficking of normal stem cells and cancer cells

scientific article published on 4 November 2013

The role of stromal-derived factor-1--CXCR7 axis in development and cancer

scientific article published on 14 October 2009

The third complement component as modulator of platelet production

scientific article published on January 2007

Thrombopoietin, but not cytokines binding to gp130 protein-coupled receptors, activates MAPKp42/44, AKT, and STAT proteins in normal human CD34+ cells, megakaryocytes, and platelets

scientific article published in July 2002

Tissue-specific muscle, neural and liver stem/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury

scientific article published in February 2004

Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis

scientific article published on 11 May 2005

Very Small Embryonic-Like Stem Cells (VSELs)

scientific article published on 01 January 2019

Very Small Embryonic-like Stem Cells and Their Potential Relevance for Kidney Homeostasis

scientific article published in 2011

Very small embryonic-like (VSEL) stem cells in adult organs and their potential role in rejuvenation of tissues and longevity

scientific article published on 14 June 2008

Very small embryonic-like (VSEL) stem cells: purification from adult organs, characterization, and biological significance

scientific article published on 06 May 2008

Very small embryonic-like stem cells are present in adult murine organs: ImageStream-based morphological analysis and distribution studies

scientific article (publication date: December 2008)

Very small embryonic-like stem cells: characterization, developmental origin, and biological significance

scientific article published on June 2008

Very small embryonic-like stem-cell optimization of isolation protocols: an update of molecular signatures and a review of current in vivo applications

scientific article published on 15 November 2013

Very small embryonic/epiblast-like stem cells (VSELs) and their potential role in aging and organ rejuvenation--an update and comparison to other primitive small stem cells isolated from adult tissues.

scientific article

Paulina is supported by:

About Paulina

Help