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List of works by Elizaveta Freinkman

6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels

scientific article published on 13 June 2019

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

scientific article

Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis.

scientific article published on 2 April 2018

Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism

scientific article published on August 2016

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

scientific article published in July 2015

Bacteria regulate choanoflagellate development with lipid activators, inhibitors, and synergists

article

Bacterial lipids activate, synergize, and inhibit a developmental switch in choanoflagellates

scientific article published on 27 June 2016

Bionectriol A, a polyketide glycoside from the fungus Bionectria sp. associated with the fungus-growing ant, Apterostigma dentigerum ⬇️

scientific article published on December 2009

Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation

scientific article published on 15 June 2016

Corrigendum: A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.

scientific article

Critical role for arginase 2 in obesity-associated pancreatic cancer

scientific article published on 14 August 2017

Cytoplasmic ATP Hydrolysis Powers Transport of Lipopolysaccharide Across the Periplasm in E. coli ⬇️

scientific article published on November 8, 2012

Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition

scientific article

Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans

scientific article

Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes

article published in the Proceedings of the National Academy of Sciences of the United States of America

Enhanced phosphocholine metabolism is essential for terminal erythropoiesis

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

scientific article published on 12 October 2016

Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes

scientific article published on 9 February 2017

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

scientific article published on 01 May 2018

Histidine catabolism is a major determinant of methotrexate sensitivity

scientific article published in Nature

JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition

scientific article published on 17 September 2018

JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.

scientific article published on 22 January 2018

LACTB is a tumour suppressor that modulates lipid metabolism and cell state

scientific article

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes.

scientific article published on 26 October 2017

Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique Vulnerabilities

scientific article published on 19 January 2016

Metabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique Vulnerabilities

scientific article published on 01 July 2020

PIK3CA mutant tumors depend on oxoglutarate dehydrogenase

scientific article published on 10 April 2017

Periodic production of retinoic acid by meiotic and somatic cells coordinates four transitions in mouse spermatogenesis.

scientific article published on 6 November 2017

Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites

scientific article

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.

scientific article

Rapid immunopurification of mitochondria for metabolite profiling and absolute quantification of matrix metabolites

scientific article published on 29 September 2017

Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer

scientific article published on 06 December 2019

Regulated assembly of the transenvelope protein complex required for lipopolysaccharide export

scientific article published on 8 June 2012

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.

scientific article

Sequence variation in G-protein-coupled receptors: analysis of single nucleotide polymorphisms

scientific article

Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death

scientific article published on 13 February 2019

Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.

scientific article published on 10 October 2017

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.

scientific article published on July 2015

Targeting tumor phenotypic plasticity and metabolic remodeling in adaptive cross-drug tolerance

scientific article published on 20 August 2019

The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel

scientific article

The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D.

scientific article published on 29 April 2014

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers

scientific article

Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential

scientific article

mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.

scientific article

mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold.

scientific article published on 23 November 2016

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