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List of works by Peter Walter

53 Signal recognition particle: A ribonucleoprotein required for cotranslational translocation of proteins, isolation and properties

scientific article published on January 1, 1983

A CHOP-regulated microRNA controls rhodopsin expression ⬇️

scientific article published on March 14, 2011

A bacterial secretory protein requires signal recognition particle for translocation across mammalian endoplasmic reticulum

scientific article published in October 1982

A case of siderosis bulbi without a radiologically detectable foreign body.

scientific article published in February 2013

A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing

scientific article

A first line of defense against ER stress ⬇️

scientific article published on August 6, 2012

A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling

scientific article

A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking

scientific article

Accuracy of intraocular lens power calculation using partial coherence interferometry in patients with high myopia

scientific article

Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome

scientific article published on 01 November 2019

An ER-mitochondria tethering complex revealed by a synthetic biology screen

scientific article

An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation

scientific article published on 10 August 2020

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

scientific article published on 05 November 2020

An unfolded protein-induced conformational switch activates mammalian IRE1.

scientific article published on 3 October 2017

Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells

scientific article

Antimyeloma Effects of the Heat Shock Protein 70 Molecular Chaperone Inhibitor MAL3-101

scientific article

Automated identification of pathways from quantitative genetic interaction data

scientific article

BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

scientific article published on June 2017

Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses

scientific article

Blue-yellow and standard pattern visual evoked potentials in phakic and pseudophakic glaucoma patients and controls

scientific article published on 4 September 2015

Bypassing a Kinase Activity with an ATP-Competitive Drug ⬇️

scientific article published on October 16, 2003

Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch.

scientific article published on 20 July 2016

Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether

scientific article published on 31 May 2019

Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress

scientific article published on 20 July 2016

Central corneal thickness determination in corneal edema using ultrasound pachymetry, a Scheimpflug camera, and anterior segment OCT.

scientific article published on 21 April 2015

Clinical observations and occurrence of complications following heavy silicone oil surgery

scientific article published on 14 April 2014

Coexpressed subunits of dual genetic origin define a conserved supercomplex mediating essential protein import into chloroplasts

scientific article published on 03 December 2020

Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1 ⬇️

scientific article published on July 6, 2011

Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma

scientific article

Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum

scientific article

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α

scientific article published on 15 December 2021

Development of a stress response therapy targeting aggressive prostate cancer.

scientific article published in May 2018

Disruption of IRE1α through its kinase domain attenuates multiple myeloma

scientific article published on 01 August 2019

ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast ⬇️

scientific article published on May 14, 2013

ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13.

scientific article

ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery

scientific article published on 22 July 2014

ERMES-mediated ER-mitochondria contacts: molecular hubs for the regulation of mitochondrial biology

scientific article

Electro-spun Membranes as Scaffolds for Human Corneal Endothelial Cells

scientific article published in January 2018

Endoplasmic reticulum stress in disease pathogenesis

scientific article published on January 2008

Endoplasmic reticulum stress sensing in the unfolded protein response

scientific article published on March 2013

Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic

scientific article published on 19 May 2015

Engineering ER-stress dependent non-conventional mRNA splicing.

scientific article published on 9 July 2018

Evaluation of Long-term Anatomic Changes Following Canaloplasty With Anterior Segment Spectral-domain Optical Coherence Tomography and Ultrasound Biomicroscopy

scientific article published on 30 November 2017

Evaluation of early anatomical changes following canaloplasty with anterior segment spectral-domain optical coherence tomography and ultrasound biomicroscopy

scientific article published on 9 December 2015

Functional genomic screen reveals genes involved in lipid-droplet formation and utilization

scientific article

Gebauer SLc Original and Moria One-Use Plus automated microkeratomes for ultrathin Descemet's stripping automated endothelial keratoplasty preparation

scientific article

Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response

scientific article published on 14 May 2020

Goldmann Applanation Tonometry versus Dynamic Contour Tonometry after Vitrectomy with Silicone Oil Endotamponade

scientific article published on 25 January 2017

Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity ⬇️

scientific article published on March 28, 2011

Identification of yeast proteins necessary for cell-surface function of a potassium channel

scientific article

Implantation of a novel telemetric intraocular pressure sensor in patients with glaucoma (ARGOS study): 1-year results

scientific article published on 22 January 2015

Influence of the prediction error of the first eye undergoing cataract surgery on the refractive outcome of the fellow eye

scientific article published on 31 October 2014

Inhibition of the integrated stress response by viral proteins that block p-eIF2-eIF2B association

scientific article published on 20 July 2020

Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury

scientific article

Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion

scientific article

Intercepting IRE1 kinase-FMRP signaling prevents atherosclerosis progression

scientific article published on 22 February 2022

Intracellular protein topogenesis

scientific article published on 01 January 1984

Long-term follow-up after implantation of a telemetric intraocular pressure sensor in patients with glaucoma: a safety report

scientific article published on 14 November 2017

Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering ⬇️

scientific article published on August 26, 2010

Mechanism of protein translocation across the endoplasmic reticulum

scientific article published on January 1, 1982

Mechanism of protein translocation across the endoplasmic reticulum membrane

scientific article published on January 1986

Messenger RNA targeting to endoplasmic reticulum stress signalling sites.

scientific article

Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress

scientific article published on 06 January 2020

Molecular Biology of the Cell ⬇️

biology textbook published by Garland Science and currently authored by Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts and Peter Walter

Multiple selection filters ensure accurate tail-anchored membrane protein targeting

scientific article

On the mechanism of sensing unfolded protein in the endoplasmic reticulum

scientific article

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

scientific article published on July 2014

Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits

scientific article

Partial Coherence Laser Interferometry in Highly Myopic versus Emmetropic Eyes.

scientific article

Pharmacological brake-release of mRNA translation enhances cognitive memory

scientific article published in 2013

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response

scientific article published on 15 April 2015

Pil1 controls eisosome biogenesis

scientific article

Pkh-kinases control eisosome assembly and organization

scientific article

Preparation of microsomal membranes for cotranslational protein translocation

scientific article published in January 1983

Protein translocation across the endoplasmic reticulum

scientific article published in August 1984

Quantitative microscopy reveals dynamics and fate of clustered IRE1α

scientific article published on 23 December 2019

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

scientific article published on 03 August 2009

Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe.

scientific article published on 25 September 2017

Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells

scientific article published on 01 April 2020

Secretion requires a cytoplasmically disposed sulphydryl of the RER membrane

scientific article published in July 1980

Seg1 controls eisosome assembly and shape ⬇️

scientific article published on August 6, 2012

Signal recognition protein is required for the integration of acetylcholine receptor delta subunit, a transmembrane glycoprotein, into the endoplasmic reticulum membrane

scientific article

Small molecule ISRIB suppresses the integrated stress response within a defined window of activation

article published in the Proceedings of the National Academy of Sciences of the United States of America

Small molecule cognitive enhancer reverses age-related memory decline in mice

scientific article published on 01 December 2020

Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation.

scientific article published on 20 July 2016

Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1

scientific article published on 30 December 2014

Structural and functional basis for RNA cleavage by Ire1 ⬇️

scientific article published on July 6, 2011

Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction

scientific article published on 30 January 2020

Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule

scientific article

Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response

scientific article published on 20 January 2016

Targeting IRE1 with small molecules counteracts progression of atherosclerosis

scientific article published on 30 January 2017

The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response

scientific article published on 15 October 2019

The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins

scientific article

The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections

scientific article

The effect of air, SF6 and C3F8 on immortalized human corneal endothelial cells

scientific article published on 6 September 2016

The effect of cataract surgery on blue-yellow and standard-pattern visual-evoked potentials

scientific article published on 17 July 2014

The integrated stress response: From mechanism to disease

scientific article

The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly

scientific article

The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1

scientific article published on 24 December 2018

The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis ⬇️

scientific article published on October 15, 2012

Topography of retinal recovery processes in humans

scientific article published on 20 October 2014

Translation from the 5' untranslated region shapes the integrated stress response

scientific article

Translational control by eIF2α phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine

scientific article published on March 2016

Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α.

scientific article

Translational control of nicotine-evoked synaptic potentiation in mice and neuronal responses in human smokers by eIF2α

scientific article published on March 2016

Translocation of a lysosomal enzyme across the microsomal membrane requires signal recognition particle ⬇️

scientific article published on August 30, 1983

Translocation of proteins across membranes: the signal hypothesis and beyond

scientific article published on January 1, 1979

Translocation of proteins across the endoplasmic reticulum

scientific article published on 01 January 1982

Tryptic dissection and reconstitution of translocation activity for nascent presecretory proteins across microsomal membranes ⬇️

scientific article published on April 1, 1979

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response ⬇️

scientific article published on August 18, 2011

Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry

scholarly article

Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer

scientific article

X-ray structures of the signal recognition particle receptor reveal targeting cycle intermediates

scientific article

eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response

scientific article

eIF2α-mediated translational control regulates the persistence of cocaine-induced LTP in midbrain dopamine neurons

scientific article published on 13 December 2016

tRNA ligase structure reveals kinetic competition between non-conventional mRNA splicing and mRNA decay

scientific article published on 25 June 2019

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