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List of works by Dale S Edgerton

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Physiologic action of glucagon on liver glucose metabolism

scientific article published on October 1, 2011
Insulin's direct effects on the liver dominate the control of hepatic glucose production

scientific article published on February 2006
Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo.

scientific article published on 15 September 2009
Small increases in insulin inhibit hepatic glucose production solely caused by an effect on glycogen metabolism

scientific article published in August 2001
Molecular Characterization of Insulin-Mediated Suppression of Hepatic Glucose Production In Vivo

scientific article published on February 25, 2010
Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs.

scientific article
The direct and indirect effects of insulin on hepatic glucose production in vivo

scientific article published on 01 September 1998
Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes

scientific article published on 22 March 2005
Current strategies for the inhibition of hepatic glucose production in type 2 diabetes

scientific article published on January 2009
Unlike mice, dogs exhibit effective glucoregulation during low-dose portal and peripheral glucose infusion

scientific article published on September 30, 2003
A novel glucagon receptor antagonist, NNC 25-0926, blunts hepatic glucose production in the conscious dog.

scientific article published on 16 February 2007
Evidence against a physiologic role for acute changes in CNS insulin action in the rapid regulation of hepatic glucose production

scientific article published on May 2, 2012
Physiological consequences of phasic insulin release in the normal animal

scientific article
Intraportal GLP-1 infusion increases nonhepatic glucose utilization without changing pancreatic hormone levels

scientific article published on 07 August 2007
Insulin action on the liver in vivo

scientific article published on November 2007
Splanchnic free fatty acid kinetics

scientific article published on June 1, 2003
Interaction between the central and peripheral effects of insulin in controlling hepatic glucose metabolism in the conscious dog.

scientific article
Glucagon as a Critical Factor in the Pathology of Diabetes

scientific article published on February 1, 2011
Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes

scientific article
Insulin's direct hepatic effect explains the inhibition of glucose production caused by insulin secretion

scientific article published on 23 March 2017
40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

article
Islet auto-transplantation into an omental or splenic site results in a normal beta cell but abnormal alpha cell response to mild non-insulin-induced hypoglycemia

scientific article
Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis.

scientific article published on 03 May 2016
Effect of 11 beta-hydroxysteroid dehydrogenase-1 inhibition on hepatic glucose metabolism in the conscious dog.

scientific article
Portal glucose infusion increases hepatic glycogen deposition in conscious unrestrained rats

scientific article published on 01 October 1999
Changes in glucose and fat metabolism in response to the administration of a hepato-preferential insulin analog.

scientific article
Effects of insulin deficiency or excess on hepatic gluconeogenic flux during glycogenolytic inhibition in the conscious dog.

scientific article published in November 2002
Impact of hematopoietic cyclooxygenase-1 deficiency on obesity-linked adipose tissue inflammation and metabolic disorders in mice

scientific article published on 27 August 2013
Intraportally delivered GLP-1, in the presence of hyperglycemia induced via peripheral glucose infusion, does not change whole body glucose utilization

scientific article published on 4 December 2007
Inhibition of dipeptidyl peptidase-4 by vildagliptin during glucagon-like Peptide 1 infusion increases liver glucose uptake in the conscious dog

scientific article published on 7 October 2008
Inhalation of insulin (Exubera) is associated with augmented disposal of portally infused glucose in dogs

scientific article published in April 2005
Effect of vagal cooling on the counterregulatory response to hypoglycemia induced by a low dose of insulin in the conscious dog.

scientific article published in March 2001
Effects of the nitric oxide donor SIN-1 on net hepatic glucose uptake in the conscious dog.

scientific article published on 20 November 2007
Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial hepatic specific 11beta hydroxysteroid dehydrogenase type 1 activity

scientific article published on 01 November 2006
Selective tonic inhibition of G-6-Pase catalytic subunit, but not G-6-P transporter, gene expression by insulin in vivo

scientific article
Triglyceride uptake and lipoprotein lipase-generated fatty acid spillover in the splanchnic bed of dogs

scientific article published on 06 April 2007
Effects of hyperglycemia on hepatic gluconeogenic flux during glycogen phosphorylase inhibition in the conscious dog.

scientific article
Effects of 11β-hydroxysteroid dehydrogenase-1 inhibition on hepatic glycogenolysis and gluconeogenesis.

scientific article published on 12 February 2013
Is Brain Insulin Action Relevant to the Control of Plasma Glucose in Humans?

scientific article published on March 1, 2015
Selective antagonism of the hepatic glucocorticoid receptor reduces hepatic glucose production

scientific article published on 01 September 2006
Inhalation of insulin in dogs: assessment of insulin levels and comparison to subcutaneous injection

scientific article published in April 2004
Inhalation of human insulin is associated with improved insulin action compared with subcutaneous injection and endogenous secretion in dogs

scientific article published on 08 September 2006
Inhalation of human insulin (exubera) augments the efficiency of muscle glucose uptake in vivo

scientific article published in December 2006
Biologic Comparison of Inhaled Insulin Formulations: ExuberaTM and Novel Spray-Dried Engineered Particles of Dextran-10

scientific article published on August 9, 2014
Glucagon's yin and yang effects on hepatic glucose production

scientific article published on June 1, 2013
Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery

article published in 2019
The effect of an acute elevation of NEFA concentrations on glucagon-stimulated hepatic glucose output

scientific article published on 11 April 2006
Glucose autoregulation is the dominant component of the hormone-independent counterregulatory response to hypoglycemia in the conscious dog.

scientific article published on 16 May 2017
Inhaled insulin is associated with prolonged enhancement of glucose disposal in muscle and liver in the canine

scientific article
Effects of intraportal exenatide on hepatic glucose metabolism in the conscious dog.

scientific article published on 14 May 2013

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