Search filters

List of works by Adamantios Mamais

A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity

scientific article

Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson's disease brains with Lewy body pathology

scientific article published on 25 July 2018

Arsenite stress down-regulates phosphorylation and 14-3-3 binding of leucine-rich repeat kinase 2 (LRRK2), promoting self-association and cellular redistribution

scientific article

Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue.

scientific article published on 27 January 2012

Detection of endogenous S1292 LRRK2 autophosphorylation in mouse tissue as a readout for kinase activity.

scientific article

Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2

scientific article published on 05 October 2018

Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases ⬇️

scientific article published on 05 June 2013

Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease

scientific article

Fine-mapping, gene expression and splicing analysis of the disease associated LRRK2 locus

scientific article

GTP binding controls complex formation by the human ROCO protein MASL1

scientific article

Genetic analysis of neurodegenerative diseases in a pathology cohort

Globular glial tauopathies (GGT) presenting with motor neuron disease or frontotemporal dementia: an emerging group of 4-repeat tauopathies

scientific article published on 21 July 2011

Hexokinases link DJ-1 to the PINK1/parkin pathway

scientific article published on 29 September 2017

Inhibition of LRRK2 kinase activity stimulates macroautophagy

scientific journal article

LRRK2 links genetic and sporadic Parkinson's disease

scientific article published on 05 March 2019

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

scientific article published on 01 October 2020

LRRK2 mediates tubulation and vesicle sorting from lysosomes

scientific article published on 11 November 2020

LRRK2: dropping (kinase) inhibitions and seeking an (immune) response

scientific article published on 24 March 2014

Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue

scientific article

Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation

scientific journal article

Phosphorylation of 4E-BP1 in the mammalian brain is not altered by LRRK2 expression or pathogenic mutations

scientific article

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

scientific article

Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice

Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis

scientific article published on 17 May 2020

The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network

scientific article published on 01 May 2020

Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils

scientific article published on 15 May 2019

mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition

scientific article published on 21 March 2018

mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1

scientific article (publication date: 12 October 2016)

Paulina is supported by:

About Paulina

Help