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List of works by Luba Trakhtenbrot

A clonal hypereosinophilic syndrome with specific and effective therapy: a report of two cases

scientific article published on 01 December 2006

A new MALDI-TOF-based assay for monitoring JAK2 V617F mutation level in patients undergoing allogeneic stem cell transplantation (allo SCT) for classic myeloproliferative disorders (MPD).

scientific article

A role for common fragile site induction in amplification of human oncogenes

scientific article published on 01 February 2002

Absence of negative growth regulation in three new murine radiation-induced myeloid leukemia cell lines with deletion of chromosome 2

scientific article published on 01 December 1992

Acquisition of a Ph chromosome with minor BCR/ABL fusion in treatment-related myelodysplastic syndrome with chromosome 7 abnormalities in a patient treated for Hodgkin disease

scientific article published in May 2005

Amplification of band q22 of chromosome 21, including AML1, in older children with acute lymphoblastic leukemia: an emerging molecular cytogenetic subgroup

scientific article published on 01 August 2003

Apaf1 in chronic myelogenous leukemia (CML) progression: reduced Apaf1 expression is correlated with a H179R p53 mutation during clinical blast crisis.

scientific article published on 23 March 2007

Assessment of the response to imatinib in chronic myeloid leukemia patients--comparison between the FISH, multiplex and RT-PCR methods.

scientific article published in October 2004

BCR-ABL transcripts are not detected in cord blood or the peripheral blood of the newborn child whose mother developed chronic myeloid leukemia while pregnant.

scientific article published on 28 July 2009

COMBO-FISH for focussed fluorescence labelling of gene domains: 3D-analysis of the genome architecture of abl and bcr in human blood cells

scientific article published on 28 November 2005

Cellular and molecular characteristics of an immortalized ataxia-telangiectasia (group AB) cell line

scientific article published on May 1989

Characterizing T cells in SCID patients presenting with reactive or residual T lymphocytes.

scientific article published on 20 November 2012

Chimerism testing and detection of minimal residual disease after allogeneic hematopoietic transplantation using the bioView (Duet) combined morphological and cytogenetical analysis

scientific article published on 01 August 2002

Chromosomal mapping of the murine c-abl proto-oncogene by in situ hybridization

scientific article published on 01 February 1990

Chromosomal numerical aberrations in apparently normal oral mucosa of heavy smokers affected by lung cancer

scientific article published on 9 December 2009

Chromosomal numerical aberrations in oral lichen planus

scientific article published in May 2009

Chromosome 13q deletion and IgH abnormalities may be both masked by near-tetraploidy in a high proportion of multiple myeloma patients: a combined morphology and I-FISH analysis.

scientific article

Clonal expansion and not cell interconversion is the basis for the neuroblast and nonneuronal types of the SK-N-SH neuroblastoma cell line ⬇️

scientific article published on May 1, 2003

Clonal expansion of a new MLL rearrangement in the absence of leukemia

scientific article published on 01 May 2005

Co-existence of clonal expanded autologous and transplacental-acquired maternal T cells in recombination activating gene-deficient severe combined immunodeficiency

scientific article

Co-existence of multiple subclones in TEL-AML1 at diagnosis of acute lymphoblastic leukaemia in association with submicroscopic deletion of AML1.

scientific article

Coexistence of several unbalanced translocations in a case of neuroblastoma: the contribution of multicolor spectral karyotyping

scientific article published on July 1999

Combined analysis of morphology and fluorescence in situ hybridization in follow-up of minimal residual disease in a child with Philadelphia-positive acute lymphoblastic leukemia

scientific article published on 01 October 2002

Comparison of triple helical COMBO-FISH and standard FISH by means of quantitative microscopic image analysis of abl/bcr positions in cell nuclei

scientific article published on 19 September 2006

Correlation between losses of IGH or its segments and deletions of 13q14 in t(11;14) (q13;q32) multiple myeloma

scientific article published on 01 January 2010

Could rhG-CSF induction of tetraploidy contribute to leukemogenesis in healthy donors?

scientific article published on 21 June 2007

Cytogenetic studies on B-cell leukemias of AKR origin

scientific article published on 01 March 1987

Deletion of chromosome 2 is an early event in the development of radiation-induced myeloid leukemia in SJL/J mice

scientific article published on 01 August 1988

Demonstration of Thymopoietin Transcripts in Different Hematopoietic Cell Lines ⬇️

scientific article published on January 1, 1995

Detection of non-diploid cells in premalignant and malignant oral lesions using combined morphological and FISH analysis - a new method for early detection of suspicious oral lesions.

scientific article published on 26 March 2007

Detection of unidentified chromosome abnormalities in human neuroblastoma by spectral karyotyping (SKY).

scientific article published on July 2001

Determination of chromosome 13 status in bone marrow cells of patients with multiple myeloma using combined morphologic and fluorescence in situ hybridization analysis

scientific article published on 01 March 2004

Diagnosis of Relapsed Burkitt's Lymphoma in a Urine Sample: an Unusual "FISHing" Expedition

scientific article published in October 2015

Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient

scientific article published on 17 February 2009

Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation

scholarly article

Evolutionary regulation of the blind subterranean mole rat, Spalax, revealed by genome-wide gene expression

scientific article

Fast‐FISH Detection and Semi‐Automated Image Analysis of Numerical Chromosome Aberrations in Hematological Malignancies ⬇️

scientific article published on January 1, 1998

Fluorescence lifetime imaging of DAPI-stained nuclei as a novel diagnostic tool for the detection and classification of B-cell chronic lymphocytic leukemia

scientific article published on 17 June 2016

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells

scientific article published on 12 October 2006

Hairy cell leukemia-variant without typical morphology and with near-tetraploid DNA content.

scientific article published on 20 December 2016

Hexasomy of chromosome 8 and trisomy of chromosome 11 characterize two karyotypically independent clones in a case of acute non-lymphocytic leukemia. Conventional cytogenetic and FISH investigation.

scientific article published in November 1995

Hyperphosphatemia during spontaneous tumor lysis syndrome culminate in severe hypophosphatemia at the time of blast crisis of Phneg CML to acute myelomoncytic leukemia

scientific article published on 29 August 2012

Identification of a region in glycoprotein IIIa involved in subunit association with glycoprotein IIb: further lessons from Iraqi-Jewish Glanzmann thrombasthenia

scientific article published on 01 August 2001

Immature leukemic CD34+CXCR4+ cells from CML patients have lower integrin-dependent migration and adhesion in response to the chemokine SDF-1.

scientific article

In vitro proliferative advantage of bone marrow cells with tetrasomy 8 in Ewing sarcoma

scientific article published on 01 September 1996

Induction of polyploidy by nuclear fusion mechanism upon decreased expression of the nuclear envelope protein LAP2β in the human osteosarcoma cell line U2OS.

scientific article published on 28 January 2014

Interphase fluorescence in situ hybridization detection of chromosome 17 and 17q region gains in neuroblastoma: are they secondary events?

scientific article published on 01 September 2002

Involvement of der(12)t(12;21)(p13;q22) and as well as additional rearrangements of chromosome 12 homolog in ETV6/RUNX1-positive acute lymphoblastic leukemia

scientific article published in April 2009

Is fluorescence in-situ hybridization sufficient in patients with myelodysplastic syndromes and insufficient cytogenetic testing?

scientific article published on 06 September 2018

Karyotypic evolution pathways in medulloblastoma/primitive neuroectodermal tumor determined with a combination of spectral karyotyping, G-banding, and fluorescence in situ hybridization.

scientific article published in February 2004

Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy ⬇️

scientific article published on June 29, 2011

Malignant transformation of normal enterocytes following downregulation of Bak expression

scientific journal article

Multilineage hematopoietic engraftment after allogeneic peripheral blood stem cell transplantation without conditioning in SCID patients

scientific article

Multiple Myeloma Presenting in Patients Younger than 50 Years of Age: A Single Institution Experience

scientific article published on 08 June 2020

Neural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21

scientific article

New insights to the MLL recombinome of acute leukemias

scientific article

Newly diagnosed multiple myeloma patients carrying monoallelic deletion of the whole locus of immunoglobulin heavy chain gene have a better prognosis compared to those with t(4;14) and t(14;16)

scientific article published on 06 February 2019

Noninvasive detection of aneuploid cells in laryngeal epithelial precursor lesions

scientific article published on 6 May 2011

Oral lichen planus patients exhibit consistent chromosomal numerical aberrations: A follow-up analysis

scientific article published on 30 July 2015

P53 in blind subterranean mole rats--loss-of-function versus gain-of-function activities on newly cloned Spalax target genes

scientific article published on 16 October 2006

Philadelphia-chromosome-positive T-lymphoblastic leukemia: acute leukemia or chronic myelogenous leukemia blastic crisis

scientific article

Polyploidization of Murine Mesenchymal Cells Is Associated with Suppression of the Long Noncoding RNA H19 and Reduced Tumorigenicity ⬇️

scientific article published on October 9, 2012

Post-essential thrombocythemia myelofibrosis and chronic myelomonocytic leukemia can co-exist with complex cytogenetic abnormalities

scientific article published on 23 July 2010

Preleukemia in experimental leukemogenesis.

scientific article published on January 1989

Preleukemia in long-term plasmacytoma-regressor mice

scientific article published on May 29, 1998

Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.

scientific article published on 3 November 2016

Reciprocal relationship between a Ph-negative clone with trisomy 8 associated with severe myelodysplasia and a Ph-positive clone following imatinib treatment in a patient with accelerated-phase chronic myelogenous leukemia (CML).

scientific article published in December 2004

Reduced expression of plakoglobin correlates with adverse outcome in patients with neuroblastoma.

scientific article published on July 2001

SKY analysis of childhood neural tumors and cell lines demonstrates a susceptibility of aberrant chromosomes to further rearrangements.

scientific article published on 2 November 2006

SKY detection of chromosome rearrangements in two cases of tMDS with a complex karyotype

scientific article published on 01 October 2002

SKY reveals a high frequency of unbalanced translocations involving chromosome 6 in t(12;21)-positive acute lymphoblastic leukemia

scientific article published on 06 April 2007

SMURF2 prevents detrimental changes to chromatin, protecting human dermal fibroblasts from chromosomal instability and tumorigenesis

scientific article published on 26 February 2020

Severe eosinophilia in children: a diagnostic dilemma.

scientific article published in May 2013

Simultaneous detection of deletions of 9q and 22q in a subgroup of chronic myelocytic leukemia Philadelphia-positive patients by a novel probe

scientific article published on 01 February 2003

Standardization criteria for the detection of BCR/ABL fusion in interphase nuclei of chronic myelogenous leukemia patients by fluorescence in situ hybridization

scientific article published on 01 December 2000

Subgroup of patients with Philadelphia-positive chronic myelogenous leukemia characterized by a deletion of 9q proximal to ABL gene: expression profiling, resistance to interferon therapy, and poor prognosis.

scientific article

Sustained Response to Imatinib in a Pediatric Patient with Concurrent Myeloproliferative Disease and Lymphoblastic Lymphoma Associated with a CCDC88C-PDGFRB Fusion Gene

scientific article published on 06 February 2019

Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer

scientific article

Tetraploid myeloid cells in donors of peripheral blood stem cells treated with rhG-CSF

scientific article published on 01 July 2003

The MLL recombinome of acute leukemias in 2013.

scientific article

The MLL recombinome of acute leukemias in 2017.

scientific article published on 13 July 2017

The SIL gene is essential for mitotic entry and survival of cancer cells.

scientific article published on 24 April 2007

The increased expression of 14q32 small nucleolar RNA transcripts in promyelocytic leukemia cells is not dependent on PML–RARA fusion gene ⬇️

scientific article published on October 12, 2012

The multiparametric scanning system for evaluation of minimal residual disease in hematological malignancies

scientific article published on January 2004

The presence of a single PML-RARA isoform lacking exon 5 in FISH-negative APL samples

scientific article published on 25 October 2007

Therapy-related acute myeloid leukemia with t(2;11)(q37;q23) after treatment for osteosarcoma.

scientific article

Three-dimensional spectral precision distance microscopy of chromatin nanostructures after triple-colour DNA labelling: a study of the BCR region on chromosome 22 and the Philadelphia chromosome

scientific article

Translocation t(11;14) in newly diagnosed patients with multiple myeloma: Is it always favorable?

scientific article published on 6 May 2016

Treatment with interferon alpha prior to discontinuation of imatinib in patients with chronic myeloid leukemia

scientific article published on 13 December 2011

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