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List of works by David Givol

"Retroposon" insertion into the cellular oncogene c-myc in canine transmissible venereal tumor

scientific article published on February 1985

A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3.

scientific article

A positive feedback mechanism in the transcriptional activation of Apaf-1 by p53 and the coactivator Zac-1.

scientific article published on February 2002

A rapid assay for drug sensitivity of glioblastoma stem cells

scientific article published on 11 May 2007

A search for bcl1, bcl2, and c-myc oncogene rearrangements in chronic lymphocytic leukemia

scientific article published on 01 January 1989

Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element ⬇️

scientific article published on December 16, 1982

Activation of the c-mos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome ⬇️

scientific article published on December 1, 1983

Allelic immunoglobulin VH genes in two mouse strains: possible germline gene recombination.

scientific article published on January 1983

Alloactivated Lyt 1 +2− T lymphoblasts bind syngeneic Ia antigens

scientific article published in Nature

Analysis of recombinant DNA clones specific for the murine p53 cellular tumor antigen ⬇️

scientific article published on January 1, 1983

Analysis of the gene coding for the murine cellular tumour antigen p53 ⬇️

scientific article published on September 1, 1984

Anti-V region framework antibodies affect the ligand binding of VL dimer ⬇️

scientific article published on January 1, 1979

Antibodies to immunoglobulin heavy chain variable regions protect helper cells from specific suicide by radiolabeled antigen

scientific article published on 01 April 1980

Antigen-binding receptors on T cells from long-term MLR. evidence of binding sites for allogeneic and self-MHC products

scientific article published on 01 January 1980

BCL6 is regulated by p53 through a response element frequently disrupted in B-cell non-Hodgkin lymphoma.

scientific article published on 25 October 2005

CD133-positive hematopoietic stem cell "stemness" genes contain many genes mutated or abnormally expressed in leukemia

scientific article published on 01 September 2005

Cloning and sequence of the cDNA corresponding to the variable region of immunoglobulin heavy chain MPC11 ⬇️

scientific article published on August 25, 1980

Combining site and antigenic determinants of the V regions

scientific article published on January 1978

Common origin of transmissible venereal tumors (TVT) in dogs

scientific article published in January 1987

Comparison of EGF receptor sequences as a guide to study the ligand binding site

scientific article published on April 1991

Comparison of the dimensions of the combining sites of the dinitrophenyl-binding immunoglobulin A myeloma proteins MOPC 315, MOPC 460 and XRPC 25 by spin-label mapping ⬇️

scientific article published on August 1, 1977

Conservation and divergence of immunoglobulin VH pseudogenes ⬇️

scientific article published on January 1, 1983

Correlated expression of VH framework and VHidiotypic determinants on T helper cells and on functionally undefined T cells binding group A streptococcal carbohydrate ⬇️

scientific article published on February 1, 1980

Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells

scientific article published on 16 September 2010

DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.

scientific article published in June 2001

DNA microarrays identification of primary and secondary target genes regulated by p53.

scientific article

Design principle of gene expression used by human stem cells: implication for pluripotency

scientific article

Developmental expression of c-kit, a proto-oncogene encoded by the W locus ⬇️

scientific article published on August 1, 1990

Developmental expression of two murine fibroblast growth factor receptors, flg and bek ⬇️

scientific article published on December 1, 1991

Dimerization and activation of the kit receptor by monovalent and bivalent binding of the stem cell factor ⬇️

scientific article published on August 5, 1992

Diversity of germ-line immunoglobulin VH genes

scientific article published in July 1981

Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups ⬇️

scientific article published on February 1, 1983

Expression of the bcl-2 gene in mouse B lymphocytic cell lines is differentiation stage specific

scientific article published on 01 April 1987

Flg-2, a new member of the family of fibroblast growth factor receptors

scientific article published on June 1, 1991

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells

scientific article published on 12 October 2006

General method for the specific isolation of peptides containing modified residues, using insoluble antibody columns ⬇️

scientific article published on July 20, 1971

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation

scientific article published on December 2011

Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer

scientific article

H-2-restricted helper factor secreted by clone hybridoma cells

scientific article published on September 1981

HIPK2 downregulates vimentin and inhibits breast cancer cell invasion.

scientific article published on 15 February 2012

HIPK2 modulates p53 activity towards pro-apoptotic transcription

scientific article published on 14 October 2009

HIPK2-a therapeutical target to be (re)activated for tumor suppression: role in p53 activation and HIF-1α inhibition.

scientific article published on April 2010

Hair growth induction by the Tellurium immunomodulator AS101: association with delayed terminal differentiation of follicular keratinocytes and ras-dependent up-regulation of KGF expression

scientific article published on 4 December 2003

Hepcidin, a key regulator of iron metabolism, is transcriptionally activated by p53.

scientific article

Homology between an endogenous viral LTR and sequences inserted in an activated cellular oncogene

scientific article published on April 1983

Identification of direct p73 target genes combining DNA microarray and chromatin immunoprecipitation analyses.

scientific article

Immunoglobulin heavy chain gene rearrangements in chronic lymphocytic leukaemia: correlation with clinical stage

scientific article

Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin

scientific article published on April 1999

Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs

scientific article published on October 1998

Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes ⬇️

scientific article published on May 12, 2003

Insertional mutagenesis and breast carcinoma

scientific article published in Nature

Interactions of the lanthanide- and hapten-binding sites in the Fv fragment from the myeloma protein MOPC 315 ⬇️

scientific article published on April 1, 1976

Isolated hapten-binding receptors of sensitized lymphocytes. IV. Expression of immimoglobulin variable regions in (4-hydroxy-3-nitrophenyl) acetyl (NP)-specific receptors isolated from murine B and T lymphocytes ⬇️

scientific article published on April 1, 1979

Isolation of peptides that inhibit binding of basic fibroblast growth factor to its receptor from a random phage-epitope library

scientific article published on November 1993

KIT ligand (mast cell growth factor) inhibits the growth of KIT-expressing melanoma cells

scientific article published on 01 August 1993

MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells.

scientific article

Mapping of Murine Fibroblast Growth Factor Receptors Refines Regions of Homology between Mouse and Human Chromosomes

scientific article published on 01 June 1994

Mechanism of activation of the mouse c-mos oncogene by the LTR of an intracisternal A-particle gene

scientific article published on December 1984

Monoclonal anti-VH antibodies recognize a common VH determinant expressed on immunoglobulin heavy chains from various species

scientific article published in July 1983

Multiple structural elements determine ligand binding of fibroblast growth factor receptors. Evidence that both Ig domain 2 and 3 define receptor specificity ⬇️

scientific article published on April 15, 1993

Nanog inhibits the switch of myogenic cells towards the osteogenic lineage

scientific article published on 26 November 2007

Nanog transforms NIH3T3 cells and targets cell-type restricted genes

scientific article

Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis.

scientific article

Nucleotide sequence of the rat skeletal muscle actin gene ⬇️

scientific article published on August 26, 1982

On the location of palindromes in immunoglobulin genes ⬇️

scientific article published on June 1, 1977

Organization and evolution of immunoglobulin VH gene subgroups

scientific article

Outcome signature genes in breast cancer: is there a unique set?

scientific article published on 12 August 2004

PCR-based identification of new receptors: molecular cloning of a receptor for fibroblast growth factors

scientific article published on May 1, 1991

PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.

scientific article

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells ⬇️

scientific article published on December 13, 1984

Polymorphism of germ-line immunoglobulin VH genes correlates with allotype and idiotype markers ⬇️

scientific article published on 01 December 1981

Polymorphism of human immunoglobulin VH genes: a possible marker of autoimmune disease

scientific article published on 01 September 1987

Preparation and characterization of anti-framework antibodies to the heavy chain variable region (VH) of mouse immunoglobulins ⬇️

scientific article published on November 1, 1978

Preparation and characterization of anti-framework antibodies to the kappa-chain variable region (V kappa) of mouse immunoglobulins

scientific article published on 01 February 1980

Preparation and characterization of antibodies to the λ chain variable region (Vλ) of mouse immunoglobulins ⬇️

scientific article published on November 1, 1978

Preparation of a semisynthetic antibody

scientific article published on April 4, 1978

Profile of gene expression regulated by induced p53: connection to the TGF-beta family

scientific article

Promoter mutations that allow nifA-independent expression of the nitrogen fixation nifHDKY operon

scientific article published on October 1983

Protein kinase C-dependent release of a functional whole extracellular domain of the mast cell growth factor (MGF) receptor by MGF-dependent human myeloid cells

scientific article published on 01 June 1994

Rearrangement of the oncogene c-mos in mouse myeloma NSI and hybridomas

scientific article published in December 1983

Receptor functions and ligand-dependent transforming potential of a chimeric kit proto-oncogene ⬇️

scientific article published on November 1, 1990

Recovery of antibody activity on reoxidation of completely reduced polyalanyl heavy chain and its Fd fragment derived from anti-2,4-dinitrophenyl antibody ⬇️

scientific article published in December 1968

Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells.

scientific article published on 31 May 2010

Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors.

scientific article published on 25 February 2010

Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs.

scientific article published on 15 May 2011

Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc.

scientific article

Retention and loss of immunoglobulin heavy chain alleles in helper T cell hybridoma clones ⬇️

scientific article published on January 1, 1983

Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown

scientific article

S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation.

scientific article published on 30 January 2006

Selective participation of immunoglobulin V region and major histocompatibility complex products in antigen binding by T cells ⬇️

scientific article published on December 1, 1978

Simple DNA sequences in homologous flanking regions near immunoglobulin VH genes: a role in gene interaction?

scientific article published on June 1982

Skeletal muscle actin mRNA. Characterization of the 3' untranslated region

scientific article published on February 1981

Solubilization of lymphocyte and thymocyte antigens by a reversible chemical modification

scientific article

Soluble c-kit proteins and antireceptor monoclonal antibodies confine the binding site of the stem cell factor ⬇️

scientific article published on February 25, 1993

Specific spin labelling of the Fc region of immunoglobulins ⬇️

scientific article published on August 1, 1977

Specificity of interactions of hapten side chains with the combining site of the myeloma protein MOPC 315 ⬇️

scientific article published on August 1, 1977

Steel factor and c-kit protooncogene: genetic lessons in signal transduction

scientific article published on January 1994

Structural organization of the murine c-kit proto-oncogene

scientific article published on July 1, 1992

Structure and activity of the translocated c-myc in mouse plasmacytoma XRPC-24.

scientific article published in January 1986

Structure of immunoglobulin gamma 2b heavy chain gene cloned from mouse embryo gene library

scientific article

Structure-function analyses of the kit receptor for the steel factor ⬇️

scientific article published on July 1, 1993

Subunit interaction in antibodies and antibody fragments studied by circular polarization of fluorescence ⬇️

scientific article published on 01 April 1975

T-cell hybridoma bearing heavy chain variable region determinants producing (T,G)-A--L-specific helper factor

scientific article published on 01 July 1980

Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha

scientific article

The 5' region of the p53 gene: evolutionary conservation and evidence for a negative regulatory element

scientific article published on December 1985

The UVB-induced gene expression profile of human epidermis in vivo is different from that of cultured keratinocytes

scientific article published on 01 April 2006

The binding of 2,4,6-trinitrophenyl derivatives to the mouse myeloma immunoglobulin A protein MOPC 315 ⬇️

scientific article published on January 1, 1978

The gross architecture of an antibody-combining site as determined by spin-label mapping ⬇️

scientific article published on August 1, 1977

The role of nitro groups in the binding of nitroaromatics to protein MOPC 315 ⬇️

scientific article published on September 1, 1978

Transposable elements and cancer

scientific article published in January 1986

Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem cells

scientific article

Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo

scientific article

Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function.

scientific article

p53 reactivation: the link to zinc

scientific article published on 15 July 2012

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