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List of works by Stephen F Previs

13C/31P NMR assessment of mitochondrial energy coupling in skeletal muscle of awake fed and fasted rats. Relationship with uncoupling protein 3 expression

scientific article published in December 2000

2 H 2 O-Based High-Density Lipoprotein Turnover Method for the Assessment of Dynamic High-Density Lipoprotein Function in Mice ⬇️

scientific article published on June 13, 2013

A Novel Biomarker of Neuronal Glutamate Metabolism in Nonhuman Primates Using Localized <sup>1</sup>H-Magnetic Resonance Spectroscopy: Development and Effects of BNC375, an α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator

scientific article published on 29 September 2020

A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis

scientific article published on 30 March 2016

A comparison of 2H2O and phenylalanine flooding dose to investigate muscle protein synthesis with acute exercise in rats

scientific article

A critical evaluation of mass isotopomer distribution analysis of gluconeogenesis in vivo

scientific article published on 01 July 1999

A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans ⬇️

scientific article published on July 1, 1995

A novel approach for assessing protein synthesis in channel catfish, Ictalurus punctatus.

scientific article published on 27 June 2009

Acute resistance exercise augments integrative myofibrillar protein synthesis

scientific article published on August 23, 2011

Akt2 is required for hepatic lipid accumulation in models of insulin resistance.

scientific article

Altered cholesterol homeostasis in cultured and in vivo models of cystic fibrosis

scientific journal article

An Improved Measurement of Isotopic Ratios by High Resolution Mass Spectrometry ⬇️

scientific article published on January 3, 2013

Analysis of Mammalian Cell Proliferation and Macromolecule Synthesis Using Deuterated Water and Gas Chromatography-Mass Spectrometry

scientific article

Assay of the 13C and 2H mass isotopomer distribution of phosphoenolpyruvate by gas chromatography/mass spectrometry

scientific article published on 01 June 1996

Assay of the concentration and 13C-labeling pattern of phenylacetylglutamine by nuclear magnetic resonance

scientific article published on 01 September 1994

Assay of the deuterium enrichment of water via acetylene

scientific article published on 01 June 1996

Assessment of cardiac proteome dynamics with heavy water: slower protein synthesis rates in interfibrillar than subsarcolemmal mitochondria.

scientific article published on March 2013

Assessment of mitochondrial energy coupling in vivo by 13C/31P NMR

scientific article

Attenuation of Slc27a5 Gene Expression Followed by LC–MS Measurement of Bile Acid Reconjugation Using Metabolomics and a Stable Isotope Tracer Strategy ⬇️

scientific article published on August 26, 2011

Brain insulin controls adipose tissue lipolysis and lipogenesis

scientific article

CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects

scientific article

Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis

scientific article

Chronic ethanol and triglyceride turnover in white adipose tissue in rats: inhibition of the anti-lipolytic action of insulin after chronic ethanol contributes to increased triglyceride degradation

scientific article published on 07 August 2007

Chronic ethanol-induced insulin resistance is associated with macrophage infiltration into adipose tissue and altered expression of adipocytokines

scientific journal article

Complicating factors in the application of the "average method" for determining the contribution of gluconeogenesis

scientific article published on June 2008

Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo.

scientific article published in December 2000

Contributions of liver and kidneys to glycerol production and utilization in the dog.

scientific article

Correction of 13C mass isotopomer distributions for natural stable isotope abundance

scientific article published on 01 March 1996

Correction: The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

scientific article published on 19 January 2017

Cumulative responses of muscle protein synthesis are augmented with chronic resistance exercise training

scientific article published on 11 October 2010

DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates

scientific article published on 20 April 2018

Demonstration of diet-induced decoupling of fatty acid and cholesterol synthesis by combining gene expression array and2H2O quantification ⬇️

scientific article published on January 15, 2012

Determination of low levels of 2H-labeling using high-resolution mass spectrometry: application in studies of lipid flux and beyond

scientific article published on February 2014

Determination of the 13C-labeling pattern of glucose by gas chromatography-mass spectrometry

scientific article published on 01 August 1993

Determination of the enrichment of the hydrogen bound to carbon 5 of glucose on 2H2O administration

scientific article published in October 2001

Diet-induced obesity alters protein synthesis: tissue-specific effects in fasted versus fed mice

scientific article published on March 2008

Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 Inhibitors

scientific article published on 12 November 2015

Disruption of IRS-2 causes type 2 diabetes in mice

scientific article

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey

scientific article published on 05 October 2016

Duodenal-jejunal bypass surgery induces hepatic lipidomic alterations associated with ameliorated hepatic steatosis in mice

scientific article published on 26 July 2016

Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats.

scientific article

Effect of Error Propagation in Stable Isotope Tracer Studies: An Approach for Estimating Impact on Apparent Biochemical Flux.

scientific article published on 19 August 2015

Effect of sampling interval on the use of "doubly labeled" water for measuring CO2 production

scientific article published on 01 February 2005

Effects of 13-Hour Hyperglucagonemia on Energy Expenditure and Hepatic Glucose Production in Humans

scientific article published on 07 October 2016

Effects of anacetrapib on plasma lipids, apolipoproteins and PCSK9 in healthy, lean rhesus macaques

scientific article published on 21 April 2014

Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice.

scientific article published on 4 July 2013

Enhanced data-independent analysis of lipids using ion mobility-TOFMSE to unravel quantitative and qualitative information in human plasma

scientific article

Enhancing studies of pharmacodynamic mechanisms via measurements of metabolic flux

scientific article

Equilibration of 2H labeling between body water and free amino acids: Enabling studies of proteome synthesis ⬇️

scientific article published on April 27, 2011

Erratum to: Localization of Fatty Acyl and Double Bond Positions in Phosphatidylcholines Using a Dual Stage CID Fragmentation Coupled with Ion Mobility Mass Spectrometry.

scientific article published on 13 July 2011

Ethylmalonic/adipic aciduria: effects of oral medium-chain triglycerides, carnitine, and glycine on urinary excretion of organic acids, acylcarnitines, and acylglycines

scientific article published in September 1991

Evaluation of CETP activity in vivo under non-steady-state conditions: influence of anacetrapib on HDL-TG flux

scientific article

Examining targeted protein degradation from physiological and analytical perspectives: Enabling translation between cells and subjects

scientific article published on 15 September 2020

Exposure to azide markedly decreases the abundance of mRNAs encoding cholesterol synthetic enzymes and inhibits cholesterol synthesis

scientific article published on March 2007

FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis

scientific article

GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy.

scientific article published on 5 June 2017

Gas chromatography-mass spectrometry assay of the (18)o enrichment of water as trimethyl phosphate

scientific article

Gaussian Process Modeling of Protein Turnover

scientific article published on 27 May 2016

Glucagon like receptor 1/ glucagon dual agonist acutely enhanced hepatic lipid clearance and suppressed de novo lipogenesis in mice

scientific article published on 24 October 2017

Glucagon receptor antagonism induces increased cholesterol absorption

scientific article

Glycation Reduces the Stability of ApoAI and Increases HDL Dysfunction in Diet-Controlled Type 2 Diabetes.

scientific article published on 25 October 2017

Glycerol production and utilization in humans: sites and quantitation

scientific article published on 01 December 1996

HDL flux is higher in patients with nonalcoholic fatty liver disease

scientific article published on 10 September 2019

Headspace analyses of acetone: a rapid method for measuring the 2H-labeling of water

scientific article published on 19 May 2010

Headspace analyses of ²H labeling of acetone: enabling studies of fatty acid oxidation in vivo

scientific article published on 17 September 2010

High-sugar diets increase cardiac dysfunction and mortality in hypertension compared to low-carbohydrate or high-starch diets.

scientific article

Hormonal regulation of intracellular lipolysis in C57BL/6J mice: effect of diet-induced adiposity and data normalization

scientific article

Identification of 2-(2'-octenyl) succinic acid in urine

scientific article published on 01 May 1990

Identifying Static and Kinetic Lipid Phenotypes by High Resolution UPLC–MS: Unraveling Diet-Induced Changes in Lipid Homeostasis by Coupling Metabolomics and Fluxomics ⬇️

article by Jose M. Castro-Perez et al published 2 September 2011 in Journal of Proteome Research

Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out mice

scientific article

In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS ⬇️

scientific article published on September 30, 2010

In vivo effects of anacetrapib on preβ HDL: improvement in HDL remodeling without effects on cholesterol absorption ⬇️

scientific article published on July 29, 2013

In vivo isotopically labeled atherosclerotic aorta plaques in ApoE KO mice and molecular profiling by matrix-assisted laser desorption/ionization mass spectrometric imaging

scientific article

Inaccuracies in selected ion monitoring determination of isotope ratios obviated by profile acquisition: nucleotide 18O/16O measurements

scientific article

Increased plasma membrane cholesterol in cystic fibrosis cells correlates with CFTR genotype and depends on de novo cholesterol synthesis

scientific article

Influence of diet on the modeling of adipose tissue triglycerides during growth

scientific article

Inhibition of cholesteryl ester transfer protein increases cholesteryl ester content of large HDL independently of HDL-to-HDL homotypic transfer: in vitro vs in vivo comparison using anacetrapib and dalcetrapib

scientific article published on 03 June 2015

Is there glucose production outside of the liver and kidney?

scientific article published on January 2009

Isotope Fractionation during Gas Chromatography Can Enhance Mass Spectrometry-Based Measures of 2H-Labeling of Small Molecules

scientific article published on 20 November 2020

Isotopologue distributions of peptide product ions by tandem mass spectrometry: quantitation of low levels of deuterium incorporation

scientific article

Key Concepts Surrounding Studies of Stable Isotope-Resolved Metabolomics

scientific article published on 01 January 2020

Limitations in estimating gluconeogenesis and Cori cycling from mass isotopomer distributions using [U-13C6]glucose

scientific article published in May 1998

Limitations in estimating gluconeogenesis and Cori cycling from mass isotopomer distributions using [U-13C6]glucose

scientific article

Limitations of the mass isotopomer distribution analysis of glucose to study gluconeogenesis. Heterogeneity of glucose labeling in incubated hepatocytes

scientific article published on 01 July 1998

Limitations of the mass isotopomer distribution analysis of glucose to study gluconeogenesis. Substrate cycling between glycerol and triose phosphates in liver

scientific article published on 01 August 1995

Lipid-lowering actions of imidazoline antihypertensive agents in metabolic syndrome X.

scientific article published on 17 January 2006

Lipidome of atherosclerotic plaques from hypercholesterolemic rabbits

scientific article

Localization of fatty acyl and double bond positions in phosphatidylcholines using a dual stage CID fragmentation coupled with ion mobility mass spectrometry

scientific article

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

scientific article published on 01 July 2000

Mapping lipogenic flux: A Gold LDI-MS approach for imaging neutral lipid kinetics

scientific article published on 25 August 2020

Mass spectrometric analysis of metabolite excretion in five Japanese patients with the late-onset form of glutaric aciduria type II

scientific article published on 01 August 1991

Measurement of apo(a) kinetics in human subjects using a microfluidic device with tandem mass spectrometry ⬇️

scientific article published on June 30, 2013

Measuring Acetyl-CoA and Acetylated Histone Turnover in vivo: Effect of a High Fat Diet

scientific article published on 16 December 2020

Measuring H218O Tracer Incorporation on a QQQ-MS Platform Provides a Rapid, Transferable Screening Tool for Relative Protein Synthesis ⬇️

scientific article published on February 10, 2012

Measuring gluconeogenesis using a low dose of 2H2O: advantage of isotope fractionation during gas chromatography

scientific article

Measuring in vivo metabolism using heavy water

scientific article

Measuring protein synthesis using metabolic 2H labeling, high-resolution mass spectrometry, and an algorithm ⬇️

scientific article published on January 20, 2011

Measuring proteome dynamics in vivo: as easy as adding water?

scientific article

Methods for measuring gluconeogenesis in vivo

scientific article

Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta are protected against diet-induced obesity

scientific article published on January 2007

Model of extreme hypoglycemia in dogs made ketotic with (R,S)-1,3-butanediol acetoacetate esters ⬇️

scientific article published on 01 July 1995

Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis

scientific article published on 21 July 2020

Multiplexed Quantification of Proglucagon-Derived Peptides by Immunoaffinity Enrichment and Tandem Mass Spectrometry after a Meal Tolerance Test

scientific article published in October 2015

New methodologies for studying lipid synthesis and turnover: Looking backwards to enable moving forwards ⬇️

scientific article published on May 22, 2013

Noninvasive probing of citric acid cycle intermediates in primate liver with phenylacetylglutamine

scientific article published on 01 May 1996

Novel application of the "doubly labeled" water method: measuring CO2 production and the tissue-specific dynamics of lipid and protein in vivo

scientific article published on 20 December 2005

Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver

article

Phenotyping of adipose, liver, and skeletal muscle insulin resistance and response to pioglitazone in spontaneously obese rhesus monkeys

scientific article published on 31 January 2017

Plasma Proteome Dynamics: Analysis of Lipoproteins and Acute Phase Response Proteins with 2H2O Metabolic Labeling ⬇️

scientific article published on March 5, 2012

Prenatal Diagnosis and Neonatal Monitoring of a Fetus with Glutaric Aciduria Type II Due to Electron Transfer Flavoprotein (β-Subunit) Deficiency

scientific article published on November 1, 1991

Preserved protein synthesis in the heart in response to acute fasting and chronic food restriction despite reductions in liver and skeletal muscle.

scientific article published on 29 April 2008

Proteome Dynamics Reveals Pro-Inflammatory Remodeling of Plasma Proteome in a Mouse Model of NAFLD

scientific article published on 21 July 2016

Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water ⬇️

scientific article published on March 3, 2012

Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS.

scientific article published on 6 March 2018

Quantifying cholesterol synthesis in vivo using (2)H(2)O: enabling back-to-back studies in the same subject

scientific article

Quantifying rates of glucose production in vivo following an intraperitoneal tracer bolus

scientific article published on 20 September 2016

Quantifying rates of protein synthesis in humans by use of 2H2O: application to patients with end-stage renal disease

scientific article published on 23 December 2003

Quantitative profiling of oxylipins in plasma and atherosclerotic plaques of hypercholesterolemic rabbits

scientific article published on 28 October 2015

Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

scientific article published on June 2000

Reply to Letter to the Editor: "The art of quantifying glucose metabolism"

scientific article published on 01 August 2017

Reproducibility of gas chromatography-mass spectrometry measurements of 2H labeling of water: application for measuring body composition in mice

scientific article published on 31 January 2006

Sources of blood glycerol during fasting

scientific article

Spatial and temporal studies of metabolic activity: contrasting biochemical kinetics in tissues and pathways during fasted and fed states

scientific article published on 26 March 2019

Stable isotope studies of phytanic acid α-oxidation: in vivo production of formic acid ⬇️

scientific article published on 01 August 1997

Stable isotope-based flux studies in nonalcoholic fatty liver disease

scientific article

Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS.

scientific article

Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts

scientific article published on 14 March 2018

Targeting a ceramide double bond improves insulin resistance and hepatic steatosis

scientific article

The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

scientific article

The application of 2H2O to measure skeletal muscle protein synthesis

scientific article

The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets

scientific article

The impact of extracellular fatty acids and oxygen tension on lipid synthesis and assembly in pancreatic cancer cells

scientific article published on 12 May 2020

The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species

scientific article

Tracer-based assessments of hepatic anaplerotic and TCA cycle flux: practicality, stoichiometry, and hidden assumptions

scientific article published on September 2015

Tracer-based estimates of protein flux in cases of incomplete product renewal: evidence and implications of heterogeneity in collagen turnover

scientific article

Tracing gluconeogenesis with deuterated water: measurement of low deuterium enrichments on carbons 6 and 2 of glucose

scientific article published on 01 May 1997

Tracking fatty acid kinetics in distinct lipoprotein fractions in vivo: a novel high-throughput approach for studying dyslipidemia in rodent models ⬇️

scientific article published on October 5, 2012

Triglyceride synthesis in epididymal adipose tissue: contribution of glucose and non-glucose carbon sources

scientific article published on 29 December 2008

Turnover of histones and histone variants in postnatal rat brain: effects of alcohol exposure

scientific article published on 23 October 2017

Use of [13C18] Oleic Acid and Mass Isotopomer Distribution Analysis to Study Synthesis of Plasma Triglycerides In Vivo: Analytical and Experimental Considerations ⬇️

scientific article published on June 10, 2013

Use of [6,6-2H2]glucose and of low-enrichment [U-13C6]-glucose for sequential or simultaneous measurements of glucose turnover by gas chromatography-mass spectrometry

scientific article published on 01 April 1994

Using 2H2O to study the influence of feeding on protein synthesis: effect of isotope equilibration in vivo vs. in cell culture.

scientific article published on 25 January 2005

Using [2H]water to quantify the contribution of de novo palmitate synthesis in plasma: Enabling back-to-back studies

scientific article published on 2 January 2018

Using isotope tracers to study metabolism: application in mouse models

scientific article published in January 2004

siRNA-mediated inhibition of SREBP cleavage-activating protein reduces dyslipidemia in spontaneously dysmetabolic rhesus monkeys

scientific article published on 06 March 2017

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