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List of works by Ian F. Tannock

"PSA-itis": knowledge of serum prostate specific antigen and other causes of anxiety in men with metaststic prostate cancer

scientific article published in December 2002

10-year analysis of the ATAC trial: wrong conclusion? ⬇️

scientific article published on 01 March 2011

1869 UTILIZATION AND IMPACT OF PERI-OPERATIVE CHEMOTHERAPY FOR MUSCLE-INVASIVE BLADDER CANCER: A POPULATION-BASED OUTCOMES STUDY

scientific article published in 2013

A National Cancer Institute of Canada clinical trials group phase II study of eniluracil (776C85) and oral 5-fluorouracil in patients with advanced squamous cell head and neck cancer

scientific article

A Phase II trial of docetaxel and cisplatin in patients with recurrent or metastatic nasopharyngeal carcinoma

scientific article published on October 2002

A comparison of cell proliferation parameters in solid and ascites Ehrlich tumors

scientific article published on 01 August 1969

A contemporary prognostic nomogram for men with hormone-refractory metastatic prostate cancer: a TAX327 study analysis

scientific article published in November 2007

A critical appraisal of the "human tumor stem-cell assay".

scientific article

A critical evaluation of the role of aromatase inhibitors as adjuvant therapy for postmenopausal women with breast cancer ⬇️

scientific article published on June 8, 2011

A critique of the fragility index - Authors' reply

scientific article published on 30 September 2019

A fatal case of Pneumocystis jirovecii pneumonia in a breast cancer patient receiving weekly paclitaxel and trastuzumab

A mechanistic cohort study evaluating cognitive impairment in women treated for breast cancer

scientific article published on 2 May 2017

A phase I trial of pantoprazole in combination with doxorubicin in patients with advanced solid tumors: evaluation of pharmacokinetics of both drugs and tissue penetration of doxorubicin

scientific article published on 12 September 2014

A phase II study of cediranib (AZD 2171) in treatment naive patients with progressive unresectable recurrent or metastatic renal cell carcinoma. A trial of the PMH phase 2 consortium ⬇️

scientific article published on January 26, 2013

A phase II study of methotrexate, vinblastine, doxorubicin and cisplatin plus recombinant human granulocyte-macrophage colony stimulating factors in patients with advanced transitional cell carcinoma.

scientific article

A phase II trial of continuous low-dose oral cyclophosphamide and celecoxib in patients with renal cell carcinoma

scientific article published on 29 September 2006

A phase II trial of sorafenib in first-line metastatic urothelial cancer: a study of the PMH Phase II Consortium

scientific article

A predictive model for survival in metastatic cancer patients attending an outpatient palliative radiotherapy clinic

scientific article published in August 2002

A prospective study examining elder-relevant outcomes in older adults with prostate cancer undergoing treatment with chemotherapy or abiraterone

scientific article published on 4 February 2016

A randomised, placebo-controlled, double-blind trial of the effects of d-methylphenidate on fatigue and cognitive dysfunction in women undergoing adjuvant chemotherapy for breast cancer

scientific article published on 31 October 2007

A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study

scientific article

A randomized double-blind placebo-controlled cross-over trial of the impact on quality of life of continuing dexamethasone beyond 24 h following adjuvant chemotherapy for breast cancer

scientific article published on 6 September 2012

A randomized trial of two dose levels of cyclophosphamide, methotrexate, and fluorouracil chemotherapy for patients with metastatic breast cancer

scientific article published in September 1988

A retrospective analysis of the relationship between changes in serum PSA, palliative response and survival following systemic treatment in a Canadian randomized trial for symptomatic hormone-refractory prostate cancer

scientific article

ASCO core values

scientific article published in December 2006

Abiraterone acetate in metastatic castration-resistant prostate cancer: a retrospective review of the Princess Margaret experience of (I) low dose abiraterone and (II) prior ketoconazole

scientific article published on 16 July 2014

Absolute benefits of medical therapies in phase III clinical trials for breast and colorectal cancer

scientific article published on 30 November 2009

Acid pH in tumors and its potential for therapeutic exploitation

scientific article published in August 1989

Activity of mitomycin C for aerobic and hypoxic cells in vitro and in vivo

scientific article published on 01 September 1983

Activity of the hypoxia-activated pro-drug TH-302 in hypoxic and perivascular regions of solid tumors and its potential to enhance therapeutic effects of chemotherapy

scientific article published on 13 December 2013

Addition of bevacizumab to chemotherapy for treatment of solid tumors: similar results but different conclusions

scientific article published on 13 December 2010

Adjuvant Radiation Therapy After Radical Nephrectomy in Patients with Localized Renal Cell Carcinoma: A Systematic Review and Meta-analysis

scientific article published on 05 November 2018

Adjuvant chemotherapy for breast cancer: discordance between physicians' perception of benefit and the results of clinical trials

scientific article published on 01 June 1994

Adjuvant chemotherapy for high‐risk urothelial transitional cell carcinoma: the Princess Margaret Hospital experience ⬇️

scientific article published on September 1, 1998

Adjuvant radiation or systemic therapy for renal cell carcinoma: A brief review ⬇️

scientific article published on July 1, 1995

Aflibercept versus placebo in combination with docetaxel and prednisone for treatment of men with metastatic castration-resistant prostate cancer (VENICE): a phase 3, double-blind randomised trial.

scientific article published on 4 June 2013

Alternative views on alternative therapies

An attempt at selective chemotherapy of hypoxic cells: triethylenemelamine and irradiation of a C3H mouse mammary tumour

scientific article published in October 1972

Analysis of the prognostic effects of inclusion in a clinical trial and of myelosuppression on survival after adjuvant chemotherapy for breast carcinoma

scientific article published on June 2001

Analysis of trials using chemotherapy for metastatic bladder cancer

scientific article published on January 1988

Analyzing the same data in two ways: a demonstration model to illustrate the reporting and misreporting of clinical trials

scientific article

Androgen receptor expression and outcomes in early breast cancer: a systematic review and meta-analysis

scientific article

Antitumor activity of nigericin and 5-(N-ethyl-N-isopropyl)amiloride: an approach to therapy based on cellular acidification and the inhibition of regulation of intracellular pH

scientific article published on 01 January 1994

Are prostate cancer clinical trial enrollment criteria and endpoints appropriate?

scientific article published on 01 February 2006

Are treatment strategies of urologic oncologists influenced by the opinions of their colleagues?

scientific article

Assessing adherence to oral chemotherapy using different measurement methods: Lessons learned from capecitabine

scientific article published on 09 September 2013

Assessing cognitive function in cancer patients

scientific article published on 15 March 2006

Assessment of study design in clinical trials for bladder cancer

scientific article published on November 1992

Assessment of tumor cell repopulation after chemotherapy for advanced ovarian cancer: pilot study

scientific article

Association between androgen receptor expression, Ki-67 and the 21-gene recurrence score in non-metastatic, lymph node-negative, estrogen receptor-positive and HER2-negative breast cancer

scientific article published on 15 June 2015

Axillary nodes dissection in breast cancer

Benefit of Adjuvant Chemotherapy and Pelvic Lymph Node Dissection in pT3 and Node Positive Bladder Cancer Patients Treated with Radical Cystectomy

scientific article published on 27 April 2016

Benefits of Adjuvant Chemotherapy for Bladder Cancer

scientific article published on 25 June 2015

Bias in reporting of end points of efficacy and toxicity in randomized, clinical trials for women with breast cancer

scientific article published on 9 January 2013

Bias in reporting of randomised clinical trials in oncology

scientific article

Biology and tumor growth

scientific article published on 01 April 1983

Bone metastases: pathophysiology and management policy

scientific article published on March 1991

Breast cancer: Tamoxifen--when more might be better

scientific article published on 05 February 2013

Broadening horizons in medical management of prostate cancer ⬇️

scientific article published on June 1, 2011

Can Oncologists Predict the Efficacy of Treatments in Randomized Trials?

scientific article published on 27 July 2020

Can modelling of PSA dynamics accelerate drug development for prostate cancer?

scientific article published on 13 December 2016

Cancer and cancer-therapy related cognitive dysfunction: an international perspective from the Venice cognitive workshop

scientific article published on 31 October 2007

Cancer: Resistance through repopulation

scientific article published on 03 December 2014

Cautionary Tails

scientific article published on 20 October 2020

Cell kinetics and chemotherapy: a critical review

scientific article published on August 1, 1978

Cell kinetics-where to now?

scientific article published on November 1980

Cell proliferation in human melanoma ⬇️

scientific article published on June 1, 1970

Changes in bone mineral density in men starting androgen deprivation therapy and the protective role of vitamin D.

scientific article published on 6 April 2013

Chemotherapy Rescues Hypoxic Tumor Cells and Induces Their Reoxygenation and Repopulation-An Effect That Is Inhibited by the Hypoxia-Activated Prodrug TH-302.

scientific article

Chemotherapy dose escalation: case unproven ⬇️

scientific article published on 01 August 1997

Chemotherapy for adenocystic carcinoma ⬇️

scientific article published on 01 August 1980

Chemotherapy for head and neck cancer

scientific article

Chemotherapy for metastatic transitional carcinoma of the urinary tract. A prospective trial of methotrexate, adriamycin, and cyclophosphamide (MAC) with cis-platinum for failure

scientific article

Chemotherapy for patients with hormone-refractory prostate cancer

scientific article published in November 2004

Chemotherapy for recurrent or metastatic carcinoma of the nasopharynx. A review of the Princess Margaret Hospital experience

scientific article

Chemotherapy with gemcitabine-containing regimens for locally recurrent or metastatic nasopharyngeal carcinoma

scientific article published in December 2002

Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate cancer: a Canadian randomized trial with palliative end points

scientific article

Chemotherapy-Based Treatment for Castration-Resistant Prostate Cancer ⬇️

scientific article published on August 15, 2011

Chemotherapy-induced infiltrative pneumonitis cases in breast cancer patients ⬇️

scientific article published on 04 January 2012

Choosing a better end point for trials of bone-protective agents.

scientific article

Cis-platinum and hormones in cancer of prostate

scientific article published on 01 September 1980

Clinical Outcomes in Men of Diverse Ethnic Backgrounds with Metastatic Castration Resistant Prostate Cancer

scientific article published on 11 April 2020

Clinical relevance of breast cancer biology.

scientific article

Clinical variables associated with PSA response to abiraterone acetate in patients with metastatic castration-resistant prostate cancer.

scientific article published on 23 January 2014

Cognitive Function in Patients With Colorectal Cancer Who Do and Do Not Receive Chemotherapy: A Prospective, Longitudinal, Controlled Study

scientific article published on 2 November 2015

Cognitive Function, Fatigue, and Menopausal Symptoms in Women Receiving Adjuvant Chemotherapy for Breast Cancer ⬇️

scientific article published on November 15, 2003

Cognitive function after chemotherapy in adults with solid tumours

scientific article published on September 2007

Cognitive function and fatigue after diagnosis of colorectal cancer

scientific article

Cognitive function in breast cancer patients receiving adjuvant chemotherapy

scientific article published in July 2000

Cognitive function, fatigue, and menopausal symptoms in breast cancer patients receiving adjuvant chemotherapy: evaluation with patient interview after formal assessment

scientific article published in October 2006

Cognitive impairment associated with chemotherapy for cancer: report of a workshop

scientific article

Collaborative clinical trials: quality or quantity?

scientific article published in February 2001

Combination chemotherapy used prior to radiation therapy for locally advanced squamous cell carcinoma of the head and neck

scientific article published on 01 June 1982

Combined modality treatment with radiotherapy and chemotherapy

scientific article published on October 1989

Comment on Angulo et al.: “A Man's got to know his limitations” ⬇️

scientific article published on 01 September 1995

Commentary on "cytoreduction nephrectomy in metastatic renal cancer: the results of Southwest Oncology Group Trial 8949"

scientific article published on 01 November 2000

Companion Diagnostics to Identify Biomarkers of Response to Anticancer Drugs Targeting the Proteome

scientific article published on 01 November 2019

Company Stock Prices Before and After Public Announcements Related to Oncology Drugs

Comparative Survival of Asian and White Metastatic Castration-Resistant Prostate Cancer Men Treated With Docetaxel

scientific article published on 29 January 2020

Comparison of Eligibility Criteria Between Protocols, Registries, and Publications of Cancer Clinical Trials

scientific article published on 25 May 2016

Comparison of absolute benefits of anticancer therapies determined by snapshot and area methods

scientific article published on 24 June 2012

Comparison of growth of human bladder cancer in tissue culture or as xenografts with clinical and pathological characteristics ⬇️

scientific article published on June 1, 1984

Compendium of unpublished phase III trials in oncology: characteristics and impact on clinical practice

scientific article published on 11 July 2011

Concurrent and sequential administration of chemotherapy and the Mammalian target of rapamycin inhibitor temsirolimus in human cancer cells and xenografts

scientific article

Concurrent cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy and radiotherapy for breast carcinoma: a well tolerated adjuvant regimen

scientific article

Conventional cancer therapy: promise broken or promise delayed? ⬇️

scientific article published on 01 May 1998

Convergent discriminitive, and predictive validity of the Prostate Cancer Specific Quality of Life Instrument (PROSQOLI) assessment and comparison with analogous scales from the EORTC QLQ-C30 and a trial-specific module. European Organisation for Re

scientific article

Cost-utility analysis of chemotherapy using paclitaxel, docetaxel, or vinorelbine for patients with anthracycline-resistant breast cancer

scientific article

Criteria of tumor response used in clinical trials of chemotherapy

Critical evaluation of disease stabilization as a measure of activity of systemic therapy: lessons from trials with arms in which patients do not receive active treatment.

scientific article

Cytokines and their relationship to the symptoms and outcome of cancer.

scientific article

Cytostatic potential of novel agents that inhibit the regulation of intracellular pH.

scientific article published on July 2002

Cytotoxicity of compounds that interfere with the regulation of intracellular pH: a potential new class of anticancer drugs

scientific article published on 01 March 1987

Death of tumor cells after intracellular acidification is dependent on stress-activated protein kinases (SAPK/JNK) pathway activation and cannot be inhibited by Bcl-2 expression or interleukin 1beta-converting enzyme inhibition ⬇️

scientific article published on July 1, 1998

Delivering affordable cancer care in high-income countries

article

Delivery of meaningful cancer care: a retrospective cohort study assessing cost and benefit with the ASCO and ESMO frameworks

scientific article published on 02 June 2017

Delivery of perioperative chemotherapy for bladder cancer in routine clinical practice

scientific article published on 10 June 2014

Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group

scientific article

Design and interpretation of clinical trials that evaluate agents that may offer protection from the toxic effects of cancer chemotherapy ⬇️

scientific article published on September 1, 1998

Design of placebo-controlled randomized trials of anticancer agents: Ethical considerations based on a review of published trials

scientific article published on 25 October 2021

Determinants of quality of life in patients with advanced cancer

scientific article published on 30 March 2010

Disclosure-in the blink of an eye

scientific article published on 01 February 2019

Disseminated intravascular coagulation as the presenting sign of metastatic prostate cancer

scientific article published on November 2006

Distribution of the anticancer drugs doxorubicin, mitoxantrone and topotecan in tumors and normal tissues.

scientific article published on 17 May 2013

Do Contemporary Randomized Controlled Trials Meet ESMO Thresholds for Meaningful Clinical Benefit?

scientific article published on 13 October 2016

Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer

scientific article (publication date: 7 October 2004)

Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study

scientific article published in January 2008

Doctor's dilemma: incorporating tumor markers into clinical decision-making

scientific article published in June 2002

Donepezil reduces cognitive impairment associated with anti-cancer drugs in a mouse model ⬇️

scientific article published on July 22, 2011

Dose escalation of gemcitabine concomitant with radiation and cisplatin for nonsmall cell lung cancer: a phase 1-2 study

scientific article published in October 2010

Drug penetration in solid tumours

scientific article (publication date: August 2006)

Drug resistance and the solid tumor microenvironment

scientific article (publication date: 3 October 2007)

Drug resistance in metastatic castration-resistant prostate cancer

scientific article

Duration of suppression of bone turnover following treatment with zoledronic acid in men with metastatic castration-resistant prostate cancer

scientific article published on 20 October 2017

Early palliative care for patients with advanced cancer: a cluster-randomised controlled trial

scientific article published on 19 February 2014

Economic evaluation of chemotherapy with mitoxantrone plus prednisone for symptomatic hormone-resistant prostate cancer: based on a Canadian randomized trial with palliative end points

scientific article published in June 1998

Editorial on "Interpretation of time-to-event outcomes in randomized trials: an online randomized experiment" by I. R. Weir et al

scientific article published on 01 January 2019

Effect of multifocality and multicentricity on outcome in early stage breast cancer: a systematic review and meta-analysis

scientific article

Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy

scientific article published on 3 February 2015

Effect of the selective estrogen receptor modulator arzoxifene on repopulation of hormone-responsive breast cancer xenografts between courses of chemotherapy

scientific article published on November 2005

Effect of transient hypoxia on sensitivity to doxorubicin in human and murine cell lines

scientific article published on April 1990

Effectiveness of specialized palliative care: a systematic review

scientific article

Effects of agents which inhibit the regulation of intracellular pH on murine solid tumours ⬇️

scientific article published on August 1, 1992

Effects of food on bioavailability of lapatinib: useful data, wrong conclusion.

scientific article

Effects of long-term androgen deprivation therapy on cognitive function over 36 months in men with prostate cancer

scientific article

Effects of the mammalian target of rapamycin inhibitor CCI-779 used alone or with chemotherapy on human prostate cancer cells and xenografts

scientific article

Efficacy and toxicity of abiraterone and docetaxel in octogenarians with metastatic castration-resistant prostate cancer

scientific article published on 7 October 2014

Endpoints of clinical trials for muscle-invasive bladder cancer

scientific article published on January 1990

Endpoints of clinical trials in invasive bladder cancer

scientific article published on October 1990

Enhanced drug delivery in rabbit VX2 tumours using thermosensitive liposomes and MRI-controlled focused ultrasound hyperthermia

scientific article published in January 2012

Environmental enrichment protects against cognitive impairment following chemotherapy in an animal model

scientific article published on 23 June 2016

Epidermal growth factor receptor overexpression and outcomes in early breast cancer: A systematic review and a meta-analysis

scientific article published on 31 October 2017

Eradication of a disease: how we cured symptomless prostate cancer

scientific article published on 01 April 2002

Ethics in oncology: consulting for the investment industry

scientific article published on February 2007

Evaluating the Value of Number of Cycles of Docetaxel and Prednisone in Men With Metastatic Castration-Resistant Prostate Cancer ⬇️

scientific article published on June 22, 2011

Evaluation of Treatment Benefit: Randomized Controlled Trials and Population-Based Observational Research ⬇️

scientific article published on August 12, 2013

Evaluation of cognitive function associated with chemotherapy: a review of published studies and recommendations for future research

scientific article published on 7 May 2007

Evaluation of the probability of spontaneous transfer of drug resistance between cells in culture

scientific article

Everolimus, when combined with exemestane, adds toxicity with minimal benefit for women with breast cancer

scientific article published on 01 August 2014

Evidence against apoptosis as a major mechanism for reproductive cell death following treatment of cell lines with anti-cancer drugs

scientific article

Evolution of clinical trial design in early drug development: systematic review of expansion cohort use in single-agent phase I cancer trials

scientific article published on 14 October 2013

Evolution of the randomized controlled trial in oncology over three decades

scientific article published on 27 October 2008

Experimental chemotherapy and concepts related to the cell cycle

scientific article published on February 1986

Experimental models of bladder cancer: a critical review

scientific article

Factors associated with failure to publish large randomized trials presented at an oncology meeting

scientific article published in July 2003

Factors that influence the penetration of methotrexate through solid tissue

scientific article

Failure of 2-deoxy-D-glucose and 5-thio-D-glucose to kill hypoxic cells of two murine tumors ⬇️

scientific article published on 01 March 1983

Failure of 5-day vinblastine infusion in the treatment of patients with advanced refractory breast cancer

scientific article published on 01 September 1982

Failure of 5-day vinblastine infusion in the treatment of patients with renal cell carcinoma

scientific article published in February 1985

Failure of short-course multiple drug chemotherapy to benefit patients with recurrent or metastatic head and neck cancer

scientific article published on 01 April 1982

Failures in Phase III: Causes and Consequences

scientific article published on 01 October 2015

False-positive results in clinical trials: multiple significance tests and the problem of unreported comparisons

scientific article published in February 1996

Fatigue in people with localized colorectal cancer who do and do not receive chemotherapy: a longitudinal prospective study.

scientific article published on 20 July 2016

Fatigue, menopausal symptoms, and cognitive function in women after adjuvant chemotherapy for breast cancer: 1- and 2-year follow-up of a prospective controlled study

scientific article published in November 2005

Flawed trials for cancer

scientific article published on 10 December 2019

Flow cytometric analysis of doxorubicin accumulation in cells from human and rodent cell lines

scientific article published on 01 January 1989

Flow cytometric calibration of intracellular pH measurements in viable cells using mixtures of weak acids and bases

scientific article published in August 1996

Gemcitabine plus cisplatin, an active regimen in advanced urothelial cancer: a phase II trial of the National Cancer Institute of Canada Clinical Trials Group

scientific article

Gemcitabine: a promising new agent in the treatment of advanced urothelial cancer ⬇️

scientific article published on December 1, 1997

Global drug development in cancer: a cross-sectional study of clinical trial registries

scientific article published on 8 October 2009

Goals of palliative cancer therapy ⬇️

scientific article published on 01 February 1993

Growth and characterization of multicellular tumor spheroids of human bladder carcinoma origin

scientific article published on 01 August 1986

Harms of Intermittent vs Continuous Androgen-Deprivation Therapy for Prostate Cancer

scientific article published on 01 April 2016

Have Investigators Forgotten How to Write?

scientific article published on 04 January 2021

Health-related quality of life in men with metastatic prostate cancer treated with prednisone alone or mitoxantrone and prednisone

scientific article

Heterogeneity of intracellular pH and of mechanisms that regulate intracellular pH in populations of cultured cells ⬇️

scientific article published on 01 May 1998

High risk of vascular events in patients with urothelial transitional cell carcinoma treated with cisplatin based chemotherapy

scientific article published on 01 December 1998

Honorary and ghost authorship in reports of randomised clinical trials in oncology

scientific article published on 5 August 2016

How American oncologists treat breast cancer: an assessment of the influence of clinical trials

scientific article published on 01 January 1991

How expert physicians would wish to be treated if they had genitourinary cancer

scientific article published on 01 November 1988

How valid are claims for synergy in published clinical studies?

scientific article published on 07 February 2012

Immunotherapy for Urothelial Cancer: Where Are the Randomized Trials?

scientific article published on 01 July 2019

Impact of androgen deprivation therapy on physical and cognitive function, as well as quality of life of patients with nonmetastatic prostate cancer

scientific article published in December 2006

Impact of androgen-deprivation therapy on cognitive function in men with nonmetastatic prostate cancer

scientific article published in November 2010

Impact of androgen-deprivation therapy on physical function and quality of life in men with nonmetastatic prostate cancer

scientific article

Impact of progression at baseline and on-treatment progression events in three large prostate cancer trials

scientific article published on 11 December 2019

Impact of spin in the abstracts of articles reporting results of randomized controlled trials in the field of cancer: the SPIIN randomized controlled trial

scientific article

Improved local control of invasive bladder cancer by concurrent cisplatin and preoperative or definitive radiation. The National Cancer Institute of Canada Clinical Trials Group

scientific article published in November 1996

Improving Treatment for Advanced Prostate Cancer

scientific article published on 01 July 2019

In Reply

In Reply

article published in 2008

In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: cyclophosphamide and BCNU.

scientific article

In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: methotrexate, 5-fluorouracil and adriamycin

scientific article

Influence of cell concentration in limiting the therapeutic benefit of P-glycoprotein reversal agents

scientific article

Influence of censoring on conclusions of trials for women with metastatic breast cancer

scientific article

Influence of concurrent medications on outcomes of men with prostate cancer included in the TAX 327 study

scientific article published on January 2013

Influence of glucose concentration on growth and formation of necrosis in spheroids derived from a human bladder cancer cell line

scientific article published on 01 June 1986

Influence of hypoxia and an acidic environment on the metabolism and viability of cultured cells: potential implications for cell death in tumors

scientific article published on 01 June 1986

Influence of low pH on cytotoxicity of paclitaxel, mitoxantrone and topotecan

scientific article published in January 1997

Influence of measurement error on assessment of response to anticancer chemotherapy: proposal for new criteria of tumor response ⬇️

scientific article published on 01 September 1984

Influence of measurement error on response rates

Influence of reduced concentration of L-glutamine on growth and viability of cells in monolayer, in spheroids, and in experimental tumours

scientific article

Influence of the proton pump inhibitor lansoprazole on distribution and activity of doxorubicin in solid tumors

scientific article

Influence of vitamin A on immunological response

scientific article

Informative censoring - a neglected cause of bias in oncology trials

scientific article published on 09 April 2020

Informing Patients About Expected Outcomes: The Efficacy-Effectiveness Gap

scientific article published on 11 March 2020

Inhibition of endosomal sequestration of basic anticancer drugs: influence on cytotoxicity and tissue penetration

scientific article published on March 2006

Inhibition of the regulation of intracellular pH: potential of 5-(N,N-hexamethylene) amiloride in tumour-selective therapy

scientific article published on October 1994

Initial biopsy Gleason score as a predictive marker for survival benefit in patients with castration-resistant prostate cancer treated with docetaxel: data from the TAX327 study

scientific article

Interleukin-2 for metastatic melanoma: treating polyuria with insulin?

scientific article published on 01 July 1990

Intermittent androgen blockade should be regarded as standard therapy in prostate cancer

scientific article published on 15 July 2008

Intra-individual variability in women with breast cancer

scientific article published on 12 March 2014

Is there a role for chemotherapy in prostate cancer?

scientific article published on September 2004

Is there evidence that chemotherapy is of benefit to patients with carcinoma of the prostate?

scientific article

Knowing your tumour?

scientific article published on 01 June 2020

Lack of evidence for a role of chemotherapy in the routine management of locally advanced head and neck cancer

scientific article

Lapatinib plus paclitaxel as first-line therapy for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: inappropriate conclusions from a company-sponsored study?

scientific article published on 2 March 2009

Levels of sex hormones have limited effect on cognition in older men with or without prostate cancer

scientific article

Limited penetration of anticancer drugs through tumor tissue: a potential cause of resistance of solid tumors to chemotherapy

scientific article published in March 2002

Limits to Personalized Cancer Medicine

scientific article

Long-term follow-up of a phase III intergroup study of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study ⬇️

scientific article published on 01 July 1997

Long-term impact of androgen-deprivation therapy on physical function and quality of life

scientific article published on 24 March 2015

Long-term outcome of radiation-based conservation therapy for invasive bladder cancer.

scientific article published on July 2007

Low-Dose Abiraterone in Metastatic Prostate Cancer: Is It Practice Changing? Facts and Facets

scientific article published on 01 March 2020

Low-Fat Abiraterone Food Effect Is of Great Consequence

scientific article published on 06 September 2018

Low-dose prophylactic platelet transfusions in recipients of an autologous peripheral blood progenitor cell transplant and patients with acute leukemia: a randomized controlled trial with a sequential Bayesian design

scientific article published in December 2004

Lysosomes, lysosomal enzymes, and cancer.

scientific article published on January 1993

M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) chemotherapy for transitional cell carcinoma: the Princess Margaret Hospital experience

scientific article published on 01 August 1989

MRI monitoring of intratumoral drug delivery and prediction of the therapeutic effect with a multifunctional thermosensitive liposome

scientific article published on 8 June 2011

Malignant pheochromocytoma of the urinary bladder

scientific article published on 01 February 2007

Malignant properties of sublines selected from a human bladder cancer cell line that contains an activated c-Ha-ras oncogene.

scientific article published in September 1988

Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017.

scientific article

Management of advanced prostate cancer after first-line chemotherapy

scientific article

Management of breast and prostate cancer: how does quality of life enter the equation?

scientific article published on May 1990

Management of decreased bone mineral density in men starting androgen-deprivation therapy for prostate cancer

scientific article published on 24 October 2008

Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015

scientific article published on 02 May 2016

Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.

scientific article published on 3 June 2015

Many men with castrate-sensitive metastatic prostate cancer should not receive chemotherapy

scientific article published on 12 December 2015

Mathematics in the realm of lapatinib: 500 + 500 = 1,500?

scientific article published on 5 May 2008

Measuring health-related quality of life

scientific article published on 01 July 1999

Measuring health-related quality of life in clinical trials that evaluate the role of chemotherapy in cancer treatment ⬇️

scientific article published on June 30, 1998

Mechanisms of Drug Resistance Related to the Microenvironment of Solid Tumors and Possible Strategies to Inhibit Them

scientific article published on July 2015

Mechanisms of interaction between radiation and drugs with potential for improvements in therapy

scientific article published on 01 January 1988

Memory loss in chemotherapy-treated rats is exacerbated in high-interference conditions and related to suppression of hippocampal neurogenesis

scientific article published on 18 December 2014

Menopausal symptoms in women undergoing chemotherapy-induced and natural menopause: a prospective controlled study

scientific article published on 14 October 2009

Meta-Analysis Evaluating the Impact of Site of Metastasis on Overall Survival in Men With Castration-Resistant Prostate Cancer

scientific article

Methods of immunosuppression for study of growth and lung colony formation by human tumor cells in mice

scientific article published on 01 April 1986

Methotrexate and mitomycin for patients with metastatic transitional cell carcinoma of the urinary tract

scientific article published on May 1983

Misonidazole increases the toxicity of BCNU for hypoxic cells

scientific article published on 01 March 1982

Molecular screening to select therapy for advanced cancer?

scientific article published on 01 May 2019

More pharmaceutical company influence?

scientific article published on 01 October 1998

Neoadjuvant chemotherapy in head and neck cancer: no way to preserve a larynx ⬇️

scientific article published on 01 February 1992

Neurobiological Mechanisms of Chemotherapy-induced Cognitive Impairment in a Transgenic Model of Breast Cancer

scientific article published on 4 November 2017

Neutrophil-to-lymphocyte ratio as a prognostic biomarker for men with metastatic castration-resistant prostate cancer receiving first-line chemotherapy: data from two randomized phase III trials.

scientific article

New perspectives in combined radiotherapy and chemotherapy treatment ⬇️

scientific article published on March 1, 1994

New therapies for castration-resistant prostate cancer: efficacy and safety

scientific article published on 04 May 2011

Nonrandomized clinical trials of cancer chemotherapy: phase II or III?

scientific article published on 01 August 1988

OP5. Economic evaluation of chemotherapy with mitoxantrone plus prednisone for symptomatic hormone resistant prostate cancer based on a Canadian randomised trial with palliative endpoints

article

On the existence of a G 0 -phase in the cell cycle

scientific article published on 01 October 1970

Oncogenic targets, magnitude of benefit, and market pricing of antineoplastic drugs

scientific article published on 23 May 2011

Oncology in 2050 - A Retrospective?

scientific article published on 25 April 2020

Outcomes and endpoints in cancer trials: bridging the divide

scientific article

Overall Survival of Black and White Men With Metastatic Castration-Resistant Prostate Cancer Treated With Docetaxel

scientific article published on 21 December 2018

Overview of Canadian trials in hormonally resistant prostate cancer

scientific article published on December 1996

Oxygen diffusion and the distribution of cellular radiosensitivity in tumours ⬇️

scientific article published on July 1, 1972

Oxygen distribution in tumours: influence on cell proliferation and implications for tumour therapy

scientific article published on 01 January 1976

PROSTATE SPECIFIC ANTIGEN RESPONSE TO MITOXANTRONE AND PREDNISONE IN PATIENTS WITH REFRACTORY PROSTATE CANCER:

Pantoprazole Affecting Docetaxel Resistance Pathways via Autophagy (PANDORA): Phase II Trial of High Dose Pantoprazole (Autophagy Inhibitor) with Docetaxel in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

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Perceived cognitive impairment in people with colorectal cancer who do and do not receive chemotherapy

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Perceptions of palliative care among patients with advanced cancer and their caregivers

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Personal prostate-specific antigen screening and treatment choices for localized prostate cancer among expert physicians

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Pharmacokinetic studies of amiloride and its analogs using reversed-phase high-performance liquid chromatography

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Pharmacological class effects of anticancer drugs: opportunities for decreasing healthcare spending

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Phase I/II study of the CAPABLE regimen for patients with poorly differentiated carcinoma of the nasopharynx ⬇️

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Phase II multicenter study of epirubicin for hormone-resistant prostatic cancer with measurable soft tissue disease.

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Phase II study of sulofenur (LY186641) in measurable metastatic renal cancer

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Population kinetics of carcinoma cells, capillary endothelial cells, and fibroblasts in a transplanted mouse mammary tumor

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Possible role of cell kinetics in prediction of the response to cancer therapy

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Potential drug interactions and duplicate prescriptions among cancer patients

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Potential for therapeutic gain from combined-modality treatment

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Preclinical development of molecular-targeted agents for cancer

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Predictive model for survival in patients with advanced cancer.

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Prognostic indices of inflammatory markers, cognitive function and fatigue for survival in patients with localised colorectal cancer.

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Prostate cancer

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Prostate-specific antigen and pain surrogacy analysis in metastatic hormone-refractory prostate cancer

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Purchasing silence

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Quality assessment of clinical trials in bladder cancer

scientific article published on 01 January 1988

Quality control in chemotherapy ⬇️

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Quality of abstracts describing randomized trials in the proceedings of American Society of Clinical Oncology meetings: guidelines for improved reporting

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Quality of cancer care

scientific article published on July 2004

Quality of life and understanding of disease status among cancer patients of different ethnic origin

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Quality of life and/or symptom control in randomized clinical trials for patients with advanced cancer

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Quality of life measurement in breast cancer patients

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Quantitative immunohistochemistry for evaluating the distribution of Ki67 and other biomarkers in tumor sections and use of the method to study repopulation in xenografts after treatment with paclitaxel

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Quantitative techniques for study of the anatomy and function of small blood vessels in tumors

scientific article published on 01 May 1969

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Raising concern about the American Society of Clinical Oncology conflict of interest policy amendment

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Randomised controlled trials and population-based observational research: partners in the evolution of medical evidence

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scientific article

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Randomized phase III trial comparing the new potent and selective third-generation aromatase inhibitor vorozole with megestrol acetate in postmenopausal advanced breast cancer patients. North American Vorozole Study Group

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Randomized, double-blind, controlled trial of mitoxantrone/prednisone and clodronate versus mitoxantrone/prednisone and placebo in patients with hormone-refractory prostate cancer and pain

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Recursive partitioning analysis of prognostic factors for survival in patients with advanced cancer

scientific article published on 19 October 2008

Reduction of intracellular pH as a possible mechanism for killing cells in acidic regions of solid tumors: effects of carbonylcyanide-3-chlorophenylhydrazone.

scientific article published in August 1989

Reduction of intracellular pH as a strategy to enhance the pH-dependent cytotoxic effects of melphalan for human breast cancer cells

scientific article

Reduction of tumour intracellular pH and enhancement of melphalan cytotoxicity by the ionophore Nigericin

scientific article published on 01 January 1995

Reflections on medical oncology: 25 years of clinical trials--where have we come and where are we going?

scientific article published on January 2008

Reflections on medical oncology: an appeal for better clinical trials and improved reporting of their results

scientific article published on 01 January 1983

Regulation of intracellular pH in subpopulations of cells derived from spheroids and solid tumours.

scientific article published in November 1993

Regulation of intracellular pH in tumor cell lines: influence of microenvironmental conditions

scientific article published on 01 August 1992

Relevance of randomised controlled trials in oncology.

scientific article

Removing the Primary Tumor after the Cancer Has Spread ⬇️

scientific article published on December 6, 2001

Reply to J. Zhu et al

scientific article published on 23 September 2013

Repopulation in murine breast tumors during and after sequential treatments with cyclophosphamide and 5-fluorouracil ⬇️

scientific article published on May 1, 2003

Repopulation of cancer cells during therapy: an important cause of treatment failure

scientific article

Reporting of Serious Adverse Drug Reactions of Targeted Anticancer Agents in Pivotal Phase III Clinical Trials ⬇️

scientific article published on 06 December 2010

Requirement of the Na+/H+ exchanger for tumor growth

scientific article published on 01 January 1989

Response

Response criteria phase II/phase III invasive bladder cancer

scientific article published on 01 January 1986

Response of Chinese hamster ovary cells to anticancer drugs under aerobic and hypoxic conditions

scientific article

Response of aerobic and hypoxic cells in a solid tumor to adriamycin and cyclophosphamide and interaction of the drugs with radiation

scientific article published on 01 December 1982

Responsibility in Advertising: An Oncologist's View ⬇️

scientific article published on 01 November 1979

Responsiveness to change in health-related quality of life in a randomized clinical trial: a comparison of the Prostate Cancer Specific Quality of Life Instrument (PROSQOLI) with analogous scales from the EORTC QLQ-C30 and a trial specific module. E

scientific article published in February 1998

Retreatment of men with metastatic castrate-resistant prostate cancer with abiraterone

scientific article published on 11 August 2014

Retreatment of patients with the same chemotherapy: implications for clinical mechanisms of drug resistance

scientific article

Reversal of ATP-binding cassette drug transporter activity to modulate chemoresistance: why has it failed to provide clinical benefit?

scientific article published on June 2013

Risk of incremental toxicities and associated costs of new anticancer drugs: a meta-analysis

scientific article published on 29 September 2014

Risks and benefits of phase 1 clinical trials evaluating new anticancer agents: a case for more innovation

scientific article published on 01 November 2004

Role of Autophagy as a Survival Mechanism for Hypoxic Cells in Tumors

scientific article published on June 2016

Scheduling of paclitaxel and gefitinib to inhibit repopulation for optimal treatment of human cancer cells and xenografts that overexpress the epidermal growth factor receptor ⬇️

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Scheduling of radiation and chemotherapy for limited-stage small-cell lung cancer: repopulation as a cause of treatment failure?

scientific article published on 01 March 2006

Screening trials are even more difficult than we thought they were

scientific article published in February 2002

Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment

scientific article

Selective estrogen receptor modulators as inhibitors of repopulation of human breast cancer cell lines after chemotherapy

scientific article published on October 2003

Sequential chemotherapy and radiation for nasopharyngeal cancer: absence of long-term benefit despite a high rate of tumor response to chemotherapy

scientific article published on 01 April 1987

Serum alkaline phosphatase changes predict survival independent of PSA changes in men with castration-resistant prostate cancer and bone metastasis receiving chemotherapy ⬇️

scientific article published on 02 October 2010

Serum lipids and outcome of early-stage breast cancer: results of a prospective cohort study

scientific article published on November 2005

Should Screen-detected Breast Cancers Be Managed Differently?

scientific article published on 01 August 2005

Should bisphosphonates be used routinely in patients with prostate cancer metastatic to bone?

scientific article published on 01 October 2002

Should docetaxel be standard of care for patients with metastatic hormone-sensitive prostate cancer? Pro and contra

scientific article

Side effects associated with the use of dexamethasone for prophylaxis of delayed emesis after moderately emetogenic chemotherapy.

scientific article published on April 2006

Simple prognostic score for metastatic castration-resistant prostate cancer with incorporation of neutrophil-to-lymphocyte ratio.

scientific article published on 3 July 2014

Slogans and donor pages of cancer centres: do they convey discordant messages?

scientific article published on 01 April 2018

Some problems related to the design and analysis of clinical trials

scientific article

Sorafenib for metastatic renal cancer: the Princess Margaret experience

scientific article

Spin and bias: the tip of the iceberg

scientific article published in July 2013

Statistical power of negative randomized controlled trials presented at American Society for Clinical Oncology annual meetings

scientific article

Studies with glycolysis-deficient cells suggest that production of lactic acid is not the only cause of tumor acidity

scientific article

Study of testosterone-guided androgen deprivation therapy in management of prostate cancer

scientific article published on 2 November 2015

Survival and PSA response of patients in the TAX 327 study who crossed over to receive docetaxel after mitoxantrone or vice versa

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Systemic therapy for non-clear cell renal cell carcinomas: a systematic review and meta-analysis

scientific article published on 02 June 2014

Systemic treatment for prostate cancer

scientific article published on 01 August 1998

Talking to a patient.

scientific article

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The Age Sensitivity of Epithelial Cells of Mouse Small Intestine ⬇️

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The Price We Pay for Progress: A Meta-Analysis of Harms of Newly Approved Anticancer Drugs

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The Tumor Microenvironment and Strategies to Improve Drug Distribution ⬇️

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The association between radiographic response and overall survival in men with metastatic castration‐resistant prostate cancer receiving chemotherapy ⬇️

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The changing face of hormonal therapy for prostate cancer

scientific article published on 01 September 2008

The chronic administration of drugs that inhibit the regulation of intracellular pH: in vitro and anti-tumour effects

scientific article

The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenase ⬇️

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The current status of adjuvant chemotherapy for bladder cancer

scientific article published on 01 November 1990

The development of risk groups in men with metastatic castration-resistant prostate cancer based on risk factors for PSA decline and survival

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The distribution of the anticancer drug Doxorubicin in relation to blood vessels in solid tumors

scientific article

The distribution of the therapeutic monoclonal antibodies cetuximab and trastuzumab within solid tumors

scientific article

The effect of chemotherapeutic agents on tumor vasculature in subcutaneous and orthotopic human tumor xenografts

scientific article

The effect of heat on antiport function and survival in mammalian cells

scientific article published on 01 February 1996

The effect of the drug lonidamine on Chinese hamster ovary cells in vitro and on experimental tumors

scientific article published on 01 September 1984

The effects of the anti-cancer drugs, methotrexate and 5-fluorouracil, on cognitive function in mice

scientific article published on 28 August 2006

The effects of vasodilating drugs on pH in tumors

scientific article published on 01 January 1999

The fate of abstracts submitted to a cancer meeting: factors which influence presentation and subsequent publication ⬇️

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The five Rs of chemotherapy

scientific article published in June 2016

The fragility of phase 3 trials supporting FDA-approved anticancer medicines: a retrospective analysis

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The hypoxia-activated ProDrug AQ4N penetrates deeply in tumor tissues and complements the limited distribution of mitoxantrone.

scientific article published on 27 January 2009

The influence of P-glycoprotein expression and its inhibitors on the distribution of doxorubicin in breast tumors

scientific article

The influence of erythropoietin on cognitive function in women following chemotherapy for breast cancer

scientific article published in February 2009

The influence of expression of P-glycoprotein on the penetration of anticancer drugs through multicellular layers

scientific article

The intra-tumoral relationship between microcirculation, interstitial fluid pressure and liposome accumulation

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The paradox of precision medicine

scientific article published on 01 June 2018

The penetration of anticancer drugs through tumor tissue as a function of cellular adhesion and packing density of tumor cells

scientific article published on January 2006

The potential of lactate and succinate to kill nutrient deprived tumor cells by intracellular acidification

scientific article published on 01 February 1991

The prognostic importance of metastatic site in men with metastatic castration-resistant prostate cancer

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The prognostic role of p53, metallothionein, P-glycoprotein, and MIB-1 in muscle-invasive urothelial transitional cell carcinoma ⬇️

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The proliferation of capillary endothelial cells

scientific article published on 01 January 1972

The radiation response of human bladder cancer assessed in vitro or as xenografts in immune-deprived mice.

scientific article published in October 1984

The recruitment of patients into clinical trials

scientific article published on June 1995

The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour ⬇️

scientific article

The relationship of body mass index and serum testosterone with disease outcomes in men with castration-resistant metastatic prostate cancer.

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The reporting of trials of adjuvant therapy for breast cancer

scientific article published on 01 November 1990

The response of viable tumor cords to a single dose of radiation

scientific article

The role of kinin receptors in cancer and therapeutic opportunities.

scientific article published on 11 December 2013

The role of systemic chemotherapy in the management of muscle-invasive bladder cancer

scientific article

The transition from phase II to phase III studies

scientific article published on 26 January 2009

The translational research chain: is it delivering the goods?

scientific article

Therapeutic potential of analogues of amiloride: inhibition of the regulation of intracellular pH as a possible mechanism of tumour selective therapy

scientific article published on February 1993

Third line chemotherapy in patients with metastatic breast cancer: an evaluation of quality of life and cost

scientific article published in April 1999

Tolerability and efficacy of docetaxel in older men with metastatic castrate-resistant prostate cancer (mCRPC) in the TAX 327 trial.

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Tolerability of the Intergroup 0099 (INT 0099) regimen in locally advanced nasopharyngeal cancer with a focus on patients' nutritional status

scientific article

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Toxicity of 5-fluorouracil for aerobic and hypoxic cells in two murine tumours

scientific article published on 01 January 1987

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Treating the patient, not just the cancer

scientific article published on 01 December 1987

Treatment of cancer with radiation and drugs

scientific article

Treatment of metastatic prostatic cancer with low-dose prednisone: evaluation of pain and quality of life as pragmatic indices of response

scientific article published on May 1989

Treatment of prostate cancer with intermittent versus continuous androgen deprivation: a systematic review of randomized trials.

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Trials in palliative treatment--have the goal posts been moved?

scientific article published in March 2008

Tumor growth and cell kinetics in chronically hypoxic animals

scientific article published on 01 July 1970

Tumor physiology and drug resistance

scientific article

Tumor physiology and resistance to chemotherapy: repopulation and drug penetration

scientific article

Tumour response to chemotherapy in animals that have been treated with the same drugs prior to tumour implantation: a model for studying host effects on apparent drug resistance

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Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity.

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scientific article

Use and misuse of waterfall plots

scientific article published on 29 October 2014

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Use of the proton pump inhibitor pantoprazole to modify the distribution and activity of doxorubicin: a potential strategy to improve the therapy of solid tumors

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Vitamin A and the radiation response of experimental tumors: an immune-mediated effect

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Xenografts of human bladder cancer in immune-deprived mice

scientific article published on 01 September 1982

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

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pH dependent cytotoxicity of N-dodecylimidazole: a compound that acquires detergent properties under acidic conditions

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