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List of works by Frances J Northington

A pilot cohort study of cerebral autoregulation and 2-year neurodevelopmental outcomes in neonates with hypoxic-ischemic encephalopathy who received therapeutic hypothermia

scientific article published on 20 October 2015

A systematic review of the role of intrapartum hypoxia-ischemia in the causation of neonatal encephalopathy.

scientific article published on December 2008

A time for cocktails and inclusion

scientific article published on 01 June 2018

A working model for hypothermic neuroprotection.

scientific article published on 16 April 2018

Accumulation of PSA-NCAM marks nascent neurodegeneration in the dorsal hippocampus after neonatal hypoxic-ischemic brain injury in mice

scientific article published on 23 July 2020

Accuracy of head ultrasound for the detection of intracranial hemorrhage in preterm neonates: Comparison with brain MRI and susceptibility-weighted imaging ⬇️

scientific article published on May 24, 2012

Adenosine modulates N-methyl-D-aspartate-stimulated hippocampal nitric oxide production in vivo

scientific article published on September 1995

Advanced Pediatric Neurosonography Techniques: Contrast-Enhanced Ultrasonography, Elastography, and Beyond

scientific article published on 27 December 2017

An Inhibitor of the Mitochondrial Permeability Transition Pore Lacks Therapeutic Efficacy Following Neonatal Hypoxia Ischemia in Mice

scientific article published on 05 March 2019

Antioxidant status alters levels of Fas-associated death domain-like IL-1B-converting enzyme inhibitory protein following neonatal hypoxia-ischemia.

scientific article published in January 2007

Apoptosis in perinatal hypoxic-ischemic brain injury: how important is it and should it be inhibited?

scientific article published on 10 October 2005

Apparent diffusion coefficient scalars correlate with near-infrared spectroscopy markers of cerebrovascular autoregulation in neonates cooled for perinatal hypoxic-ischemic injury

scientific article

Ascending Lipopolysaccharide-Induced Intrauterine Inflammation in Near-Term Rabbits Leading to Newborn Neurobehavioral Deficits

scientific article published on 01 January 2018

Blood Biomarkers for Evaluation of Perinatal Encephalopathy

scientific article

Blood biomarkers for evaluation of perinatal encephalopathy: state of the art.

scientific article published on 17 January 2018

Blood biomarkers for neonatal hypoxic-ischemic encephalopathy in the presence and absence of sentinel events

scientific article published on 06 October 2020

Brain injury in neonatal incontinentia pigmenti: the role of multimodality neuroimaging

scientific article

Breathing and temperature control disrupted by morphine and stabilized by clonidine in neonatal rats.

scientific article published on 5 July 2014

Brief update on animal models of hypoxic-ischemic encephalopathy and neonatal stroke

scientific article

Cannabinoid receptor expression in peripheral arterial chemoreceptors during postnatal development

scientific article published in October 2004

Cell therapy for neonatal hypoxia-ischemia and cerebral palsy

scientific article published in May 2012

Cerebral Autoregulation and Conventional and Diffusion Tensor Imaging Magnetic Resonance Imaging in Neonatal Hypoxic-Ischemic Encephalopathy.

scientific article published on 2 April 2018

Cerebrovascular autoregulation and neurologic injury in neonatal hypoxic-ischemic encephalopathy.

scientific article published on 13 August 2013

Characterization of MRI techniques to assess neonatal brain oxygenation and blood flow

scientific article published on 30 April 2019

Characterization of ionotropic glutamate receptor-mediated nitric oxide production in vivo in rats

scientific article published in April 1997

Chorioamnionitis in Rats Precipitates Extended Postnatal Inflammatory Lymphocyte Hyperreactivity

scientific article published on 28 March 2019

Clinical and neuroimaging features as diagnostic guides in neonatal neurology diseases with cerebellar involvement

scientific article

Communication Challenges in Neonatal Encephalopathy

scientific article published on 3 August 2016

Correlation Between White Matter Injury Identified by Neonatal Diffusion Tensor Imaging and Neurodevelopmental Outcomes Following Term Neonatal Asphyxia and Therapeutic Hypothermia: An Exploratory Pilot Study

scientific article published on 09 May 2019

Delayed injury of hippocampal interneurons after neonatal hypoxia-ischemia and therapeutic hypothermia in a murine model

scientific article published on 01 August 2018

Delayed neural network degeneration after neonatal hypoxia-ischemia

scientific article

Delayed neurodegeneration in neonatal rat thalamus after hypoxia-ischemia is apoptosis.

scientific article

Diffusion Tensor Imaging Detects Occult Cerebellar Injury in Severe Neonatal Hypoxic-Ischemic Encephalopathy

scientific article published on 18 January 2017

Does diffusion tensor imaging-based tractography at 3 months of age contribute to the prediction of motor outcome after perinatal arterial ischemic stroke?

scientific article published on 20 October 2011

Dorsolumbosacral agenesis, nonterminal myelocystocele and secondary tonsillar herniation: prenatal and postnatal MRI evaluation and pathological correlation

scientific article published on 26 September 2013

EEG Monitoring Technique Influences the Management of Hypoxic-Ischemic Seizures in Neonates Undergoing Therapeutic Hypothermia.

scientific article published on 17 January 2017

Effect of hyperoxic exposure during early development on neurotrophin expression in the carotid body and nucleus tractus solitarii

scientific article

Endoplasmic reticulum pathology and stress response in neurons precede programmed necrosis after neonatal hypoxia-ischemia

scientific article

Evidence for Sexual Dimorphism in the Response to TLR3 Activation in the Developing Neonatal Mouse Brain: A Pilot Study

article

Extended Combined Neonatal Treatment With Erythropoietin Plus Melatonin Prevents Posthemorrhagic Hydrocephalus of Prematurity in Rats

Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as "continuum" phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain

scientific article published on 2 August 2007

GLT1, glial glutamate transporter, is transiently expressed in neurons and develops astrocyte specificity only after midgestation in the ovine fetal brain

scientific article

Gentamicin pharmacokinetics in neonates undergoing therapeutic hypothermia

scientific article published on April 2013

Glial fibrillary acidic protein as a biomarker for neonatal hypoxic-ischemic encephalopathy treated with whole-body cooling ⬇️

scientific article published on June 15, 2011

Glial fibrillary acidic protein as a biomarker for periventricular white matter injury

scientific article published on March 2013

Head Ultrasound Resistive Indices Are Associated With Brain Injury on Diffusion Tensor Imaging Magnetic Resonance Imaging in Neonates With Hypoxic-Ischemic Encephalopathy

scientific article published on 24 August 2020

Head Ultrasound in Neonatal Hypoxic-Ischemic Injury and Its Mimickers for Clinicians: A Review of the Patterns of Injury and the Evolution of Findings Over Time

scientific article published on 22 June 2018

Hypoxia-ischemia and therapeutic hypothermia in the neonatal mouse brain--a longitudinal study

scientific article

Imaging neurodegeneration in the mouse hippocampus after neonatal hypoxia-ischemia using oscillating gradient diffusion MRI.

scientific article published on 04 October 2013

In vivo high-resolution diffusion tensor imaging of the mouse brain

scientific article published on 12 June 2013

Increased morbidity in severe early intrauterine growth restriction

scientific article published on July 2004

Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice

scientific article

Large fetal sacrococcygeal teratomas: could early delivery improve outcome?

scientific article

Later cooling within 6 h and temperatures outside 33-34 °C are not associated with dysfunctional autoregulation during hypothermia for neonatal encephalopathy

scientific article published on 08 April 2020

Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI.

scientific article

Necrostatin-1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia-ischemia

scientific article

Neonatal Hypoxic-Ischemic Encephalopathy Yields Permanent Deficits in Learning Acquisition: A Preclinical Touchscreen Assessment

scientific article published on 05 June 2020

Neonatal brain imaging and the identification of metabolic acidemia and hypoxic-ischemic encephalopathy

scientific article

Neonatal head ultrasonography today: a powerful imaging tool!

scientific article

Neonatal mice lacking functional Fas death receptors are resistant to hypoxic-ischemic brain injury

scientific article

Neonatal neuroimaging findings in congenital myotonic dystrophy

Neonatal neuroimaging findings in inborn errors of metabolism

scientific article published on 07 May 2012

Neuronal cell death in neonatal hypoxia-ischemia

scientific article published on May 2011

Newborn Cerebrovascular Responses after First Trimester Moderate Maternal Ethanol Exposure in Sheep ⬇️

scientific article published on July 1, 1997

Ontogeny of retrograde labeled chemoafferent neurons in the newborn rat nodose-petrosal ganglion complex: an ex vivo preparation

scientific article published in August 2005

Optimizing Cerebral Autoregulation May Decrease Neonatal Regional Hypoxic-Ischemic Brain Injury

scientific article published on 16 December 2016

Oscillating gradient diffusion MRI reveals unique microstructural information in normal and hypoxia-ischemia injured mouse brains

scientific article

Oscillating gradient diffusion kurtosis imaging of normal and injured mouse brains

scientific article published on 30 March 2018

Oscillating-gradient diffusion magnetic resonance imaging detects acute subcellular structural changes in the mouse forebrain after neonatal hypoxia-ischemia

scientific article published in January 2018

P-450 epoxygenase and NO synthase inhibitors reduce cerebral blood flow response to N-methyl-D-aspartate

scientific article published on 01 October 2000

PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury

scientific article published in September 2004

Parent Experience of Neonatal Encephalopathy

scientific article published on 8 December 2016

Perinatal inflammation/infection and its association with correction of metabolic acidosis in hypoxic-ischemic encephalopathy

scientific article published on 21 January 2016

Perinatal risk factors for severe injury in neonates treated with whole-body hypothermia for encephalopathy

scientific article published on 18 March 2014

Plasma and CSF Candidate Biomarkers of Neonatal Encephalopathy Severity and Neurodevelopmental Outcomes

scientific article published on 28 June 2020

Prenatal cerebellar hemorrhage: fetal and postnatal neuroimaging findings and postnatal outcome

scientific article published on 29 January 2015

Prenatal opioid exposure: The next neonatal neuroinflammatory disease

scientific article published on 22 November 2019

Preschool Language Outcomes following Perinatal Hypoxic-Ischemic Encephalopathy in the Age of Therapeutic Hypothermia

scientific article published on 05 June 2019

Programmed Necrosis: A Prominent Mechanism of Cell Death following Neonatal Brain Injury

scientific article

Quantification of white matter injury following neonatal stroke with serial DTI.

scientific article

Reduction of caspase-8 and -9 cleavage is associated with increased c-FLIP and increased binding of Apaf-1 and Hsp70 after neonatal hypoxic/ischemic injury in mice overexpressing Hsp70

scientific journal article

Relationships between cerebral autoregulation and markers of kidney and liver injury in neonatal encephalopathy and therapeutic hypothermia

scientific article published on 4 May 2017

Repetitive Neonatal Erythropoietin and Melatonin Combinatorial Treatment Provides Sustained Repair of Functional Deficits in a Rat Model of Cerebral Palsy.

scientific article

Reply to: is there really a need to adjust gentamicin dosing in neonates treated with hypothermia?

scientific article published in December 2013

Risk factors for periventricular white matter injury in very low birthweight neonates.

scientific article published on 7 October 2015

Seizure Susceptibility Correlates with Brain Injury in Male Mice Treated with Hypothermia after Neonatal Hypoxia-Ischemia

scientific article published on 28 February 2019

Sex specific correlation between GABAergic disruption in the dorsal hippocampus and flurothyl seizure susceptibility after neonatal hypoxic-ischemic brain injury

scientific article published on 09 December 2020

Sex-specific associations between cerebrovascular blood pressure autoregulation and cardiopulmonary injury in neonatal encephalopathy and therapeutic hypothermia

scientific article published on 31 January 2017

Sexual dimorphism in BDNF signaling after neonatal hypoxia-ischemia and treatment with necrostatin-1.

scientific article published on 17 December 2013

Steady pulsed imaging and labeling scheme for noninvasive perfusion imaging

scientific article

Susceptibility weighted imaging of the neonatal brain

scientific article

The Johns Hopkins Neurosciences Intensive Care Nursery Tenth Anniversary (2009-2019): A Historical Reflection and Vision for the Future

scientific article published on 01 January 2020

The Role of Diffusion Tensor Imaging in Detecting Hippocampal Injury Following Neonatal Hypoxic-Ischemic Encephalopathy

scientific article published on 16 October 2018

The search continues: neuroprotection for all neonates with hypoxic-ischemic encephalopathy

scientific article published in October 2017

Therapeutic Hypothermia Provides Variable Protection against Behavioral Deficits after Neonatal Hypoxia-Ischemia: A Potential Role for Brain-Derived Neurotrophic Factor

scientific article published on 15 February 2017

Toll-like receptor-3 activation increases the vulnerability of the neonatal brain to hypoxia-ischemia

scientific article published on July 2013

Transfontanellar duplex brain ultrasonography resistive indices as a prognostic tool in neonatal hypoxic-ischemic encephalopathy before and after treatment with therapeutic hypothermia

scientific article published on 26 November 2015

Treatment advances in neonatal neuroprotection and neurointensive care

scientific article published on April 2011

Ultrasound Predicts White Matter Integrity after Hypothermia Therapy in Neonatal Hypoxic-Ischemic Injury

scientific article published on 17 June 2019

Umbilical Cord Blood NOS1 as a Potential Biomarker of Neonatal Encephalopathy.

scientific article published on 22 May 2017

Variability of resistive indices in the anterior cerebral artery during fontanel compression in preterm and term neonates measured by transcranial duplex sonography

scientific article published on 13 February 2014

Which neuroprotective agents are ready for bench to bedside translation in the newborn infant?

scientific article published on 9 February 2012

White-gray matter echogenicity ratio and resistive index: sonographic bedside markers of cerebral hypoxic-ischemic injury/edema?

scientific article published on 25 August 2011

X chromosome-linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia-ischemia through up-regulation of mitochondrial antioxidants

scientific article published on 4 December 2007

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