List of works - Ei-ichi Negishi

1,4-Pentenyne as a five-carbon synthon for efficient and selective syntheses of natural products containing 2,4-dimethyl-1-penten-1,5-ylidene and related moieties by means of Zr-catalyzed carboalumination of alkynes and alkenes

scientific article published in January 2008

A convenient and genuine equivalent to HZrCp2Cl generated in situ from ZrCp2Cl2-DIBAL-H

scientific article published on 01 August 2006

A genealogy of Pd-catalyzed cross-coupling

A new protocol for the enantioselective synthesis of methyl-substituted alkanols and their derivatives through a hydroalumination/ zirconium-catalyzed alkylalumination tandem process

scientific article published on 01 June 2002

A novel, highly selective, and general methodology for the synthesis of 1,5-diene-containing oligoisoprenoids of all possible geometrical combinations exemplified by an iterative and convergent synthesis of coenzyme Q(10)

scientific article published on 01 January 2002

A profile of Professor Richard F. Heck

A quarter of a century of explorations in organozirconium chemistry

scientific article

Anti-Carbometalation of Homopropargyl Alcohols and Their Higher Homologues via Non-Chelation-ControlledSyn-Carbometalation and Chelation-Controlled Isomerization†

Catalytic enantioselective synthesis of chiral organic compounds of ultra-high purity of >99% ee

scientific article

Catalytic, efficient, and syn-selective construction of deoxypolypropionates and other chiral compounds via Zr-catalyzed asymmetric carboalumination of allyl alcohol

scientific article published in March 2006

Clean Inversion of Configuration in the Pd-Catalyzed Cross-Coupling of 2-Bromo-1,3-dienes ⬇️

scientific article published on November 12, 2003

Diastereoselective, Enantioselective, and Regioselective Carboalumination Reactions Catalyzed by Zirconocene Derivatives

Effects of organometals on the palladium-catalyzed tandem carbopalladation-cross coupling for preparing stereodefined exocyclic alkenes

scholarly article by Ei-ichi Negishi et al published January 1990 in Tetrahedron Letters

Efficient and selective synthesis of (S,R,R,S,R,S)-4,6,8,10,16,18-hexamethyl-docosane via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA reaction)

scientific article published on 15 February 2008

Efficient and selective synthesis of 6,7-Dehydrostipiamide via Zr-catalyzed asymmetric carboalumination and Pd-catalyzed cross-coupling of organozincs

scientific article

Enantioselective synthesis of chiral isotopomers of 1-alkanols by a ZACA-Cu-catalyzed cross-coupling protocol

scientific article published on 28 October 2014

Fully reagent-controlled asymmetric synthesis of (-)-spongidepsin via the Zr-catalyzed asymmetric carboalumination of alkenes (ZACA reaction).

scientific article published on 21 June 2007

Highly Efficient, Convergent, and Enantioselective Synthesis of Phthioceranic Acid

scientific article published on 18 June 2015

Highly Enantiospecific Borylation for Chiral α-Amino Tertiary Boronic Esters

scientific article published on 19 October 2018

Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling

scientific article published on December 2006

Highly efficient asymmetric synthesis of fluvirucinine A1 via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA)-lipase-catalyzed acetylation tandem process

scientific article published on 13 December 2007

Highly enantioselective synthesis of γ-, δ-, and ε-chiral 1-alkanols via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA)-Cu- or Pd-catalyzed cross-coupling

scientific article

Highly general stereo-, regio-, and chemo-selective synthesis of terminal and internal conjugated enynes by the Pd-catalysed reaction of alkynylzinc reagents with alkenyl halides

Highly regio- and stereoselective synthesis of (Z)-trisubstituted alkenes via propyne bromoboration and tandem Pd-catalyzed cross-coupling

scientific article published on September 2009

Highly regioselective generation of “thermodynamic” enolates and their direct characterization by NMR

Highly selective synthesis of conjugated dienoic and trienoic esters via alkyne elementometalation–Pd-catalyzed cross-coupling ⬇️

scientific article published on June 27, 2011

Highly stereo- and regioselective synthesis of (Z)-trisubstituted alkenes via 1-bromo-1-alkyne hydroboration-migratory insertion-Zn-promoted iodinolysis and Pd-catalyzed organozinc cross-coupling

scientific article

Highly stereoselective total synthesis of fully hydroxy-protected mycolactones A and B and their stereoisomerization upon deprotection

scientific article published on 15 March 2011

Magical power of transition metals: past, present, and future (Nobel Lecture).

scientific article published on 29 June 2011

Molecular tuning of the closed shell C-H···F-C hydrogen bond

scientific article

Palladium-catalyzed alkynylation.

scientific article

Recent advances in efficient and selective synthesis of di-, tri-, and tetrasubstituted alkenes via Pd-catalyzed alkenylation-carbonyl olefination synergy

scientific article

Search for highly efficient, stereoselective, and practical synthesis of complex organic compounds of medicinal importance as exemplified by the synthesis of the C21-C37 fragment of amphotericin B.

scientific article published on 03 September 2013

Synthesis and Reactivity of Zirconocene Derivatives

article

Total synthesis of (+)-scyphostatin featuring an enantioselective and highly efficient route to the side-chain via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA)

scientific article published on 23 February 2010

Use of InCl(3) as a cocatalyst and a Cl(2)Pd(DPEphos)-P(2-furyl)(3) catalyst system for one-pot hydrometalation-cross-coupling and carbometalation-cross-coupling tandem processes

scientific article published on 01 May 2004

Widely applicable synthesis of enantiomerically pure tertiary alkyl-containing 1-alkanols by zirconium-catalyzed asymmetric carboalumination of alkenes and palladium- or copper-catalyzed cross-coupling

scientific article published on 13 May 2013

Zirconocene-promoted stereoselective bicyclization of 1,6- and 1,7-dienes to produce trans-zirconabicyclo[3.3.0]octanes and cis-zirconabicyclo[4.3.0]nonanes

Zirconocenes

article

List of works by Ei-ichi Negishi

1,4-Pentenyne as a five-carbon synthon for efficient and selective syntheses of natural products containing 2,4-dimethyl-1-penten-1,5-ylidene and related moieties by means of Zr-catalyzed carboalumination of alkynes and alkenes

A convenient and genuine equivalent to HZrCp2Cl generated in situ from ZrCp2Cl2-DIBAL-H

A genealogy of Pd-catalyzed cross-coupling

A new protocol for the enantioselective synthesis of methyl-substituted alkanols and their derivatives through a hydroalumination/ zirconium-catalyzed alkylalumination tandem process

A novel, highly selective, and general methodology for the synthesis of 1,5-diene-containing oligoisoprenoids of all possible geometrical combinations exemplified by an iterative and convergent synthesis of coenzyme Q(10)

A profile of Professor Richard F. Heck

A quarter of a century of explorations in organozirconium chemistry

Anti-Carbometalation of Homopropargyl Alcohols and Their Higher Homologues via Non-Chelation-ControlledSyn-Carbometalation and Chelation-Controlled Isomerization†

Catalytic enantioselective synthesis of chiral organic compounds of ultra-high purity of >99% ee

Catalytic, efficient, and syn-selective construction of deoxypolypropionates and other chiral compounds via Zr-catalyzed asymmetric carboalumination of allyl alcohol

Clean Inversion of Configuration in the Pd-Catalyzed Cross-Coupling of 2-Bromo-1,3-dienes ⬇️

Diastereoselective, Enantioselective, and Regioselective Carboalumination Reactions Catalyzed by Zirconocene Derivatives

Effects of organometals on the palladium-catalyzed tandem carbopalladation-cross coupling for preparing stereodefined exocyclic alkenes

Efficient and selective synthesis of (S,R,R,S,R,S)-4,6,8,10,16,18-hexamethyl-docosane via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA reaction)

Efficient and selective synthesis of 6,7-Dehydrostipiamide via Zr-catalyzed asymmetric carboalumination and Pd-catalyzed cross-coupling of organozincs

Enantioselective synthesis of chiral isotopomers of 1-alkanols by a ZACA-Cu-catalyzed cross-coupling protocol

Fully reagent-controlled asymmetric synthesis of (-)-spongidepsin via the Zr-catalyzed asymmetric carboalumination of alkenes (ZACA reaction).

Highly Efficient, Convergent, and Enantioselective Synthesis of Phthioceranic Acid

Highly Enantiospecific Borylation for Chiral α-Amino Tertiary Boronic Esters

Highly efficient and selective synthesis of conjugated triynes and higher oligoynes of biological and materials chemical interest via palladium-catalyzed alkynyl-alkenyl coupling

Highly efficient asymmetric synthesis of fluvirucinine A1 via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA)-lipase-catalyzed acetylation tandem process

Highly enantioselective synthesis of γ-, δ-, and ε-chiral 1-alkanols via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA)-Cu- or Pd-catalyzed cross-coupling

Highly general stereo-, regio-, and chemo-selective synthesis of terminal and internal conjugated enynes by the Pd-catalysed reaction of alkynylzinc reagents with alkenyl halides

Highly regio- and stereoselective synthesis of (Z)-trisubstituted alkenes via propyne bromoboration and tandem Pd-catalyzed cross-coupling

Highly regioselective generation of “thermodynamic” enolates and their direct characterization by NMR

Highly selective synthesis of conjugated dienoic and trienoic esters via alkyne elementometalation–Pd-catalyzed cross-coupling ⬇️

Highly stereo- and regioselective synthesis of (Z)-trisubstituted alkenes via 1-bromo-1-alkyne hydroboration-migratory insertion-Zn-promoted iodinolysis and Pd-catalyzed organozinc cross-coupling

Highly stereoselective total synthesis of fully hydroxy-protected mycolactones A and B and their stereoisomerization upon deprotection

Magical power of transition metals: past, present, and future (Nobel Lecture).

Molecular tuning of the closed shell C-H···F-C hydrogen bond

Palladium-catalyzed alkynylation.

Recent advances in efficient and selective synthesis of di-, tri-, and tetrasubstituted alkenes via Pd-catalyzed alkenylation-carbonyl olefination synergy

Search for highly efficient, stereoselective, and practical synthesis of complex organic compounds of medicinal importance as exemplified by the synthesis of the C21-C37 fragment of amphotericin B.

Synthesis and Reactivity of Zirconocene Derivatives

Total synthesis of (+)-scyphostatin featuring an enantioselective and highly efficient route to the side-chain via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA)

Use of InCl(3) as a cocatalyst and a Cl(2)Pd(DPEphos)-P(2-furyl)(3) catalyst system for one-pot hydrometalation-cross-coupling and carbometalation-cross-coupling tandem processes

Widely applicable synthesis of enantiomerically pure tertiary alkyl-containing 1-alkanols by zirconium-catalyzed asymmetric carboalumination of alkenes and palladium- or copper-catalyzed cross-coupling

Zirconocene-promoted stereoselective bicyclization of 1,6- and 1,7-dienes to produce trans-zirconabicyclo[3.3.0]octanes and cis-zirconabicyclo[4.3.0]nonanes

Zirconocenes