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List of works by Klemen Strle

A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease

scientific article

A novel human autoantigen, endothelial cell growth factor, is a target of T and B cell responses in patients with Lyme disease

scientific article published on January 2013

An expanded population of pathogenic regulatory T cells in giant cell arteritis is abrogated by IL-6 blockade therapy

scientific article

Annexin A2 is a target of autoimmune T and B cell responses associated with synovial fibroblast proliferation in patients with antibiotic-refractory Lyme arthritis

scientific article published on 14 July 2015

Antibodies to endothelial cell growth factor and obliterative microvascular lesions in the synovium of patients with antibiotic-refractory lyme arthritis

scientific article

Association of a Toll-like receptor 1 polymorphism with heightened Th1 inflammatory responses and antibiotic-refractory Lyme arthritis

scientific article published on May 2012

Borrelia burgdorferi RST1 (OspC type A) genotype is associated with greater inflammation and more severe Lyme disease

scientific article

Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis

scientific article published on 17 June 2019

Borrelia burgdorferi stimulates macrophages to secrete higher levels of cytokines and chemokines than Borrelia afzelii or Borrelia garinii

scientific article published on December 2009

Borrelia burgdorferi stimulation of chemokine secretion by cells of monocyte lineage in patients with Lyme arthritis

scientific article published on September 9, 2010

C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts

scientific article published on 15 June 2006

CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells

scientific article published on 20 March 2019

Clinical correlations with Porphyromonas gingivalis antibody responses in patients with early rheumatoid arthritis

scientific article published on January 2013

Cytokine-hormone interactions: tumor necrosis factor alpha impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts

scientific article

Detection of Borrelia burgdorferi Cell-free DNA in Human Plasma Samples for Improved Diagnosis of Early Lyme Borreliosis

scientific article published on 25 June 2020

Diagnostic Utility of CXCL13 in Lyme Neuroborreliosis

scientific article published on 28 March 2020

Differences in Genotype, Clinical Features, and Inflammatory Potential of Borrelia burgdorferi sensu stricto Strains from Europe and the United States

scientific article published on May 2016

Dysregulation of CD4+CD25(high) T cells in the synovial fluid of patients with antibiotic-refractory Lyme arthritis.

scientific article published on June 2013

Elevated levels of IL-23 in a subset of patients with post-lyme disease symptoms following erythema migrans

scientific article

Evaluation of Modified 2-Tiered Serodiagnostic Testing Algorithms for Early Lyme Disease

scientific article published on 27 January 2017

Evidence of the Immune Relevance of Prevotella copri, a Gut Microbe, in Patients With Rheumatoid Arthritis

scientific article published on 18 November 2016

IL-10 Prevents Apoptosis of Brain Endothelium during Bacteremia

scientific article published on May 20, 2011

IL-10 promotes survival of microglia without activating Akt.

scientific article published in January 2002

IL-1beta impairs insulin-like growth factor i-induced differentiation and downstream activation signals of the insulin-like growth factor i receptor in myoblasts.

scientific article

IL-1beta suppresses prolonged Akt activation and expression of E2F-1 and cyclin A in breast cancer cells

scientific article published on June 2004

Impact of pre-existing treatment with statins on the course and outcome of tick-borne encephalitis

scientific article published in PLoS ONE

Induction of IL-10 by Borrelia burgdorferi is regulated by the action of CD14-dependent p38-MAPK and cAMP-mediated chromatin remodeling

scientific article published on 8 January 2018

Inflammatory Immune Responses in Patients with Tick-Borne Encephalitis: Dynamics and Association with the Outcome of the Disease

scientific article published on 31 October 2019

Inflammatory Immune Responses in the Pathogenesis of Tick-Borne Encephalitis.

scientific article published on 22 May 2019

Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes

scientific article published on June 11, 2012

Interferon-gamma production in Lyme arthritis synovial tissue promotes differentiation of fibroblast-like synoviocytes into immune effector cells

scientific article published on 04 January 2019

Lyme Disease in Humans

scientific article published on 11 December 2020

Lyme Disease-Associated IgG4 Autoantibodies Correlate with Synovial Pathology in Antibiotic-Refractory Lyme Arthritis.

scientific article

Matrix metalloproteinase-10 is a target of T and B cell responses that correlate with synovial pathology in patients with antibiotic-refractory Lyme arthritis

scientific article published on 24 February 2016

MicroRNA Expression Shows Inflammatory Dysregulation and Tumor-Like Proliferative Responses in Joints of Patients With Postinfectious Lyme Arthritis.

scientific article published on 11 January 2017

Multiplexed detection and quantification of human antibody response to COVID-19 infection using a plasmon enhanced biosensor platform

scientific article published on 09 October 2020

Novel activity of an anti-inflammatory cytokine: IL-10 prevents TNFalpha-induced resistance to IGF-I in myoblasts.

scientific article

Performance of United States serologic assays in the diagnosis of Lyme borreliosis acquired in Europe

scientific article

Posttreatment Symptoms in Lyme Borreliosis

scientific article published on 29 January 2020

Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide.

scientific article published on 15 July 2004

Prototypical anti-inflammatory cytokine IL-10 prevents loss of IGF-I-induced myogenin protein expression caused by IL-1beta

scientific article

Regulation of IGF-I function by proinflammatory cytokines: at the interface of immunology and endocrinology

scientific article

Reply to Parvu and Parvu

scientific article published on 26 January 2014

Reply to Seligman et Al

scientific article published on 07 May 2014

Robust interferon signature and suppressed tissue repair gene expression in synovial tissue from patients with postinfectious, Borrelia burgdorferi-induced Lyme arthritis

scientific article published on 17 October 2018

T-Helper 17 Cell Cytokine Responses in Lyme Disease Correlate With Borrelia burgdorferi Antibodies During Early Infection and With Autoantibodies Late in the Illness in Patients With Antibiotic-Refractory Lyme Arthritis

scientific article published on 11 January 2017

Tick-Specific Borrelial Antigens Appear to Be Upregulated in American but Not European Patients With Lyme Arthritis, a Late Manifestation of Lyme Borreliosis

scientific article published on June 12, 2013

Treg cell numbers and function in patients with antibiotic-refractory or antibiotic-responsive Lyme arthritis

scientific article

Two rheumatoid arthritis-specific autoantigens correlate microbial immunity with autoimmune responses in joints

scientific article published on 26 June 2017