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Authors whose works are in public domain in at least one jurisdiction

List of works by Victoria Ploplis

51-100 of 139 results

The generation and characterization of mice expressing a plasmin-inactivating active site mutation

scientific article

Humoral immune response to 2,4-dinitrophenyl--keyhole limpet hemocyanin in antigen-free, germ-free and conventional BALB/c mice

scientific article published on 01 January 1994

Early platelet dysfunction in a rodent model of blunt traumatic brain injury reflects the acute traumatic coagulopathy found in humans

scientific article

Functional differences between Streptococcus pyogenes cluster 1 and cluster 2b streptokinases are determined by their β‐domains

scientific article published on 07 March 2013

The lack of binding of VEK-30, an internal peptide from the group A streptococcal M-like protein, PAM, to murine plasminogen is due to two amino acid replacements in the plasminogen kringle-2 domain.

scientific article published on 26 November 2007

A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice

scientific article published on 13 March 2009

The urokinase plasminogen activator receptor (uPAR) controls macrophage phagocytosis in intestinal inflammation

scientific article published on 21 May 2014

Plasminogen activator inhibitor-1 stimulates macrophage activation through Toll-like Receptor-4.

scientific article published on 14 June 2016

A key role for the urokinase plasminogen activator (uPA) in invasive Group A streptococcal infection

scientific article

Direct Host Plasminogen Binding to Bacterial Surface M-protein in Pattern D Strains of Streptococcus pyogenes Is Required for Activation by Its Natural Coinherited SK2b Protein

scientific article published on June 12, 2015

CovRS-Regulated Transcriptome Analysis of a Hypervirulent M23 Strain of Group A Streptococcus pyogenes Provides New Insights into Virulence Determinants

scientific article published on July 27, 2015

Genomic Characterization of a Pattern D Streptococcus pyogenes emm53 Isolate Reveals a Genetic Rationale for Invasive Skin Tropicity

scientific article published on 04 April 2016

Fibrinolysis in Trauma: "Myth," "Reality," or "Something in Between".

scientific article published on 20 February 2017

The β-domain of cluster 2b streptokinase is a major determinant for the regulation of its plasminogen activation activity by cellular plasminogen receptors

scientific article published on January 31, 2014

A deficiency of uPAR alters endothelial angiogenic function and cell morphology

scientific article

Calorimetric evaluation of the existence of separate domains in bovine prothrombin

scientific article published on 01 January 1981

Targeting plasminogen activator inhibitor-1: role in cell signaling and the biology of domain-specific knock-in mice

scientific article published on September 2007

Expression of human plasminogen cDNA in a baculovirus vector-infected insect cell system

scientific article published in June 1989

Early coagulation events induce acute lung injury in a rat model of blunt traumatic brain injury.

scientific article published on 17 May 2016

Fibrinogen has chaperone-like activity

scientific article published on 04 December 2008

Blood component therapy in trauma guided with the utilization of the perfusionist and thromboelastography

scientific article published on September 1, 2011

The existence of independent domain structures in human Lys77-plasminogen

scientific article published on May 25, 1981

Dimerization is not a determining factor for functional high affinity human plasminogen binding by the group A streptococcal virulence factor PAM and is mediated by specific residues within the PAM a1a2 domain.

scientific article

Systemic platelet dysfunction is the result of local dysregulated coagulation and platelet activation in the brain in a rat model of isolated traumatic brain injury

scientific article published on 21 May 2014

Severe deficiency of coagulation Factor VII results in spontaneous cardiac fibrosis in mice

scientific article

Restoration of thrombolytic potential in plasminogen-deficient mice by bolus administration of plasminogen

scientific article published on 01 August 1996

Streptococcus pyogenes Employs Strain-dependent Mechanisms of C3b Inactivation to Inhibit Phagocytosis and Killing of Bacteria

scientific article published on March 4, 2016

Variable region in streptococcal M-proteins provides stable binding with host fibrinogen for plasminogen-mediated bacterial invasion

scientific article published on 9 March 2017

Phenotypic differentiation of Streptococcus pyogenes populations is induced by recombination-driven gene-specific sweeps

scientific article published on 8 November 2016

Abrogation of Plasminogen Activator Inhibitor-1-Vitronectin Interaction Ameliorates Acute Kidney Injury in Murine Endotoxemia

scientific article published on March 23, 2015

Neutralization of Streptolysin S-Dependent and Independent Inflammatory Cytokine IL-1β Activity Reduces Pathology During Early Group A Streptococcal Skin Infection

scientific article published on 03 July 2018

Spleen cells from antigen-minimized mice are superior to spleen cells from germ-free and conventional mice in the stimulation of primary in vitro proliferative responses to nominal antigens

scientific article published on 01 January 1995

Activation of band 3 mediates group A Streptococcus streptolysin S-based beta-haemolysis

scientific article published on 18 January 2016

Influence of plasminogen deficiency on the contribution of polymorphonuclear leucocytes to fibrin/ogenolysis: studies in plasminogen knock-out mice.

scientific article

Growth and behavioral development in plasminogen gene-targeted mice.

scientific article published in March 1999

Focal arterial inflammation is augmented in mice with a deficiency of the protein C gene

scientific article published on 01 December 2006

Monoclonal antibodies to discrete regions of human Glu1-plasminogen

scientific article published on 01 November 1982

Attenuation of neointima formation following arterial injury in PAI-1 deficient mice.

scientific article published in January 2001

The ex vivo reversibility of dabigatran-induced whole-blood coagulopathy as monitored by thromboelastography: mechanistic implications for clinical medicine

scientific article published on 10 July 2012

Targeted Thromboelastographic (TEG) Blood Component and Pharmacologic Hemostatic Therapy in Traumatic and Acquired Coagulopathy

scientific article published on 10 March 2016

A fibrin specific monoclonal antibody which interferes with the fibrinolytic effect of tissue plasminogen activator

scientific article published on 01 June 1988

An accompanying genetic severe deficiency of tissue factor protects mice with a protein C deficiency from lethal endotoxemia

scientific article

Combined factor VII/protein C deficiency results in intrauterine coagulopathy in mice

scientific article published on April 2000

Endoluminal arterial injury in plasminogen-deficient mice

scientific article published in June 2000

Conformationally organized lysine isosteres in Streptococcus pyogenes M protein mediate direct high-affinity binding to human plasminogen.

scientific article published on 19 July 2017

The vitronectin‐binding domain of plasminogen activator inhibitor‐1 plays an important functional role in lipopolysaccharide‐induced lethality in mice

scientific article published on December 1, 2012

Abnormal whole blood thrombi in humans with inherited platelet receptor defects

scientific article

Gene targeting in hemostasis. plasminogen

scientific article

gamma-Glutamate and beta-hydroxyaspartate in proteins

scientific article

Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation.

scientific article published on 23 March 2017