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List of works by Tetsuo Sawai

A new simple assay for determining aminoglycoside inactivation in intact cells of Pseudomonas aeruginosa

scientific article published on 01 January 1997

A novel glycylcycline, 9-(N,N-dimethylglycylamido)-6-demethyl-6-deoxytetracycline, is neither transported nor recognized by the transposon Tn10-encoded metal-tetracycline/H+ antiporter

scientific article

Appearance in Japan of highly macrolide-resistant Escherichia coli producing macrolide 2'-phosphotransferase II.

scientific article

Appearance of fosfomycin resistant Rahnella aquatilis clinically isolated in Japan.

scientific article

Aspartic acid-66 is the only essential negatively charged residue in the putative hydrophilic loop region of the metal-tetracycline/H+ antiporter encoded by transposon Tn10 of Escherichia coli

scientific article published on September 8, 1992

Association of rpoB mutations with rifampicin resistance in Mycobacterium avium

scientific article published on 20 December 2005

Delta pH-dependent accumulation of tetracycline in Escherichia coli

scientific article published on January 1991

Determination of a transmembrane segment using cysteine-scanning mutants of transposon Tn10-encoded metal-tetracycline/H+ antiporter.

scientific article

Difference in pathway of Escherichia coli outer membrane permeation between penicillins and cephalosporins

scientific article published in February 1985

Effect of EM201, an in vivo metabolite of erythromycin (EM), on signal transduction of IL-2 receptor

scientific article published in June 2004

Effect of interaction between outer membrane permeability and beta-lactamase production on resistance to beta-lactam agents in gram-negative bacteria.

scientific article

Effects of magnesium and sodium ions on the outer membrane permeability of cephalosporins in Escherichia coli.

scientific article

Effects of sulfhydryl reagents on the Cys65 mutant of the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli.

scientific article

Energetics of tetracycline efflux system encoded by Tn10 in Escherichia coli.

scientific article published in December 1985

His257 is a uniquely important histidine residue for tetracycline/H+ antiport function but not mandatory for full activity of the transposon Tn10-encoded metal-tetracycline/H+ antiporter

scientific article

Hot spots for sulfhydryl inactivation of Cys mutants in the widely conserved sequence motifs of the metal-tetracycline/H+ antiporter of Escherichia coli.

scientific article

Identification of Escherichia coli clinical isolates producing macrolide 2'-phosphotransferase by a highly sensitive detection method.

scientific article published in October 1998

Identification of porins in outer membrane of Proteus, Morganella, and Providencia spp. and their role in outer membrane permeation of beta-lactams

scientific article

Identification of the active site of Citrobacter freundii beta-lactamase using dansyl-penicillin

scientific article published on 01 June 1987

Kinetic studies on inactivation of Citrobacter freundii cephalosporinase by sulbactam ⬇️

scientific article published on July 1, 1983

Kinetic studies on the inhibition of Proteus vulgaris beta-lactamase by imipenem ⬇️

scientific article published on January 1, 1984

Kinetic study on the inhibition of type Ib penicillinase by imipenem and thienamycin.

scientific article

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by a transposon Tn10. Histidine 257 plays an essential role in H+ translocation.

scientific article

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by a transposon, Tn10. The role of the conserved dipeptide, Ser65-Asp66, in tetracycline transport

scientific article

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by transposon Tn10. Roles of the aspartyl residues located in the putative transmembrane helices ⬇️

scientific article published on April 15, 1992

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by transposon Tn10. The role of a conserved sequence motif, GXXXXRXGRR, in a putative cytoplasmic loop between helices 2 and 3 ⬇️

scientific article published on September 25, 1992

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by transposon Tn10. The structural resemblance and functional difference in the role of the duplicated sequence motif between hydrophobic segments 2 and 3 and segments 8 and 9.

scientific article

Novel Fosfomycin resistance of Pseudomonas aeruginosa clinical isolates recovered in Japan in 1996.

scientific article published on July 2000

Novel carbapenem derivative SF2103A: studies on the mode of beta-lactamase inactivation ⬇️

scientific article published on March 1, 1984

Orientation of the carboxyl terminus of the transposon Tn10-encoded tetracycline resistance protein in Escherichia coli

scientific article published in June 1990

Outer membrane permeation of beta-lactam antibiotics in Escherichia coli, Proteus mirabilis, and Enterobacter cloacae

scientific article published on October 1982

Purification and characterization of two kinds of porins from the Enterobacter cloacae outer membrane ⬇️

scientific article published on June 1, 1984

Reconstitution of the metal‐tetracycline/H+ antiporter of Escherichia coli in proteoliposomes including F0F1‐ATPase ⬇️

scientific article published on October 23, 1995

Second-site mutation of Ala-220 to Glu or Asp suppresses the mutation of Asp-285 to Asn in the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli.

scientific article

Second-site suppressor mutations for the Asp-66-->Cys mutant of the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli

scientific article

Serine residues responsible for tetracycline transport are on a vertical stripe including Asp-84 on one side of transmembrane helix 3 in transposon Tn10-encoded tetracycline/H+ antiporter of Escherichia coli.

scientific article published in July 1992

Site-specificity of the second-site suppressor mutation of the Asp-285-->Asn mutant of metal-tetracycline/H+ antiporter of Escherichia coli and the effects of amino acid substitutions at the first and second sites.

scientific article published in January 1995

Stoichiometry of metal-tetracycline/H+antiport mediated by transposon Tn10-encoded tetracycline resistance protein inEscherichia coli ⬇️

scientific article published on May 6, 1991

Substrate‐induced acceleration of N‐ethylmaleimide reaction with the Cys‐65 mutant of the transposon Tn 10‐encoded metal‐tetracycline/H+ antiporter depends on the interaction of Asp‐66 with the substrate ⬇️

scientific article published on March 27, 1995

The in vivo assembly and function of the N- and C-terminal halves of the Tn10-encoded TetA protein in Escherichia coli.

scientific article

The role of histidine residues conserved in the putative ATP-binding region of macrolide 2'-phosphotransferase II.

scientific article published in March 2004

The tetracycline efflux protein encoded by the tet(K) gene from Staphylococcus aureus is a metal-tetracycline/H+ antiporter.

scientific article published in May 1995

Transport of divalent cations with tetracycline as mediated by the transposon Tn10-encoded tetracycline resistance protein

scientific article

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