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List of works by Akihito Yamaguchi

A novel glycylcycline, 9-(N,N-dimethylglycylamido)-6-demethyl-6-deoxytetracycline, is neither transported nor recognized by the transposon Tn10-encoded metal-tetracycline/H+ antiporter

scientific article

Asp-285 of the metal-tetracycline/H+ antiporter of Escherichia coli is essential for substrate binding.

scientific article

Aspartic acid-66 is the only essential negatively charged residue in the putative hydrophilic loop region of the metal-tetracycline/H+ antiporter encoded by transposon Tn10 of Escherichia coli

scientific article published on September 8, 1992

Combined aortic root replacement and pectus excavatum correction in Marfan's syndrome

scientific article published on 01 November 2010

Complete cysteine-scanning mutagenesis and site-directed chemical modification of the Tn10-encoded metal-tetracycline/H+ antiporter

scientific article

Cysteine-scanning mutagenesis around transmembrane segments 1 and 11 and their flanking loop regions of Tn10-encoded metal-Tetracycline/H+ antiporter

scientific article published on 01 June 2000

Delta pH-dependent accumulation of tetracycline in Escherichia coli

scientific article published on January 1991

Determination of a transmembrane segment using cysteine-scanning mutants of transposon Tn10-encoded metal-tetracycline/H+ antiporter.

scientific article

Difference in pathway of Escherichia coli outer membrane permeation between penicillins and cephalosporins

scientific article published in February 1985

Effect of interaction between outer membrane permeability and beta-lactamase production on resistance to beta-lactam agents in gram-negative bacteria.

scientific article

Effects of magnesium and sodium ions on the outer membrane permeability of cephalosporins in Escherichia coli.

scientific article

Effects of sulfhydryl reagents on the Cys65 mutant of the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli.

scientific article

Energetics of tetracycline efflux system encoded by Tn10 in Escherichia coli.

scientific article published in December 1985

His257 is a uniquely important histidine residue for tetracycline/H+ antiport function but not mandatory for full activity of the transposon Tn10-encoded metal-tetracycline/H+ antiporter

scientific article

Hot spots for sulfhydryl inactivation of Cys mutants in the widely conserved sequence motifs of the metal-tetracycline/H+ antiporter of Escherichia coli.

scientific article

Identification of porins in outer membrane of Proteus, Morganella, and Providencia spp. and their role in outer membrane permeation of beta-lactams

scientific article

Identification of the active site of Citrobacter freundii beta-lactamase using dansyl-penicillin

scientific article published on 01 June 1987

Kinetic studies on inactivation of Citrobacter freundii cephalosporinase by sulbactam ⬇️

scientific article published on July 1, 1983

Kinetic studies on the inhibition of Proteus vulgaris beta-lactamase by imipenem ⬇️

scientific article published on January 1, 1984

Kinetic study on the inhibition of type Ib penicillinase by imipenem and thienamycin.

scientific article

Mercaptide formed between the residue Cys70 and Hg2+ or Co2+ behaves as a functional positively charged side chain operative in the Arg70-->Cys mutant of the metal-tetracycline/H+ antiporter of Escherichia coli.

scientific article

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by a transposon Tn10. Histidine 257 plays an essential role in H+ translocation.

scientific article

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by a transposon, Tn10. The role of the conserved dipeptide, Ser65-Asp66, in tetracycline transport

scientific article

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by transposon Tn10. Roles of the aspartyl residues located in the putative transmembrane helices ⬇️

scientific article published on April 15, 1992

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by transposon Tn10. The role of a conserved sequence motif, GXXXXRXGRR, in a putative cytoplasmic loop between helices 2 and 3 ⬇️

scientific article published on September 25, 1992

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by transposon Tn10. The structural resemblance and functional difference in the role of the duplicated sequence motif between hydrophobic segments 2 and 3 and segments 8 and 9.

scientific article

Molecular construction of a multidrug exporter system, AcrAB: molecular interaction between AcrA and AcrB, and cleavage of the N-terminal signal sequence of AcrA.

scientific article

Monoclonal antibody that binds to the central loop of the Tn10-encoded metal tetracycline/H+ antiporter of Escherichia coli

scientific article

Novel carbapenem derivative SF2103A: studies on the mode of beta-lactamase inactivation ⬇️

scientific article published on March 1, 1984

Orientation of the carboxyl terminus of the transposon Tn10-encoded tetracycline resistance protein in Escherichia coli

scientific article published in June 1990

Proximity of periplasmic loops in the metal-Tetracycline/H(+) antiporter of Escherichia coli observed on site-directed chemical cross-linking.

scientific article

Reconstitution of the metal‐tetracycline/H+ antiporter of Escherichia coli in proteoliposomes including F0F1‐ATPase ⬇️

scientific article published on October 23, 1995

Role of the charge interaction between Arg(70) and Asp(120) in the Tn10-encoded metal-tetracycline/H(+) antiporter of Escherichia coli.

scientific article

Roles of Conserved Arginine Residues in the Metal−Tetracycline/H+ Antiporter of Escherichia coli ⬇️

scientific article published on April 21, 1998

Screening of an Inhibitor of the Tetracycline Efflux Pump in a Tetracycline-Resistant Clinical-Isolate of Staphylococcus aureus 743 ⬇️

scientific article published on July 1, 1998

Second-site mutation of Ala-220 to Glu or Asp suppresses the mutation of Asp-285 to Asn in the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli.

scientific article

Second-site suppressor mutations for the Asp-66-->Cys mutant of the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli

scientific article

Serine residues responsible for tetracycline transport are on a vertical stripe including Asp-84 on one side of transmembrane helix 3 in transposon Tn10-encoded tetracycline/H+ antiporter of Escherichia coli.

scientific article published in July 1992

Site-specificity of the second-site suppressor mutation of the Asp-285-->Asn mutant of metal-tetracycline/H+ antiporter of Escherichia coli and the effects of amino acid substitutions at the first and second sites.

scientific article published in January 1995

Stoichiometry of metal-tetracycline/H+antiport mediated by transposon Tn10-encoded tetracycline resistance protein inEscherichia coli ⬇️

scientific article published on May 6, 1991

Substrate‐induced acceleration of N‐ethylmaleimide reaction with the Cys‐65 mutant of the transposon Tn 10‐encoded metal‐tetracycline/H+ antiporter depends on the interaction of Asp‐66 with the substrate ⬇️

scientific article published on March 27, 1995

Tetracycline/H+ antiporter was degraded rapidly in Escherichia coli cells when truncated at last transmembrane helix and this degradation was protected by overproduced GroEL/ES.

scientific article

The in vivo assembly and function of the N- and C-terminal halves of the Tn10-encoded TetA protein in Escherichia coli.

scientific article

The tetracycline efflux protein encoded by the tet(K) gene from Staphylococcus aureus is a metal-tetracycline/H+ antiporter.

scientific article published in May 1995

Transmembrane glutamic acid residues play essential roles in the metal-tetracycline/H+ antiporter of Staphylococcus aureus.

scientific article

Transmembrane remote conformational suppression of the Gly-332 mutation of the Tn10-encoded metal-tetracycline/H+ antiporter.

scientific article

Transport of divalent cations with tetracycline as mediated by the transposon Tn10-encoded tetracycline resistance protein

scientific article

[Bacterial resistance mechanisms for tetracyclines]

scientific article published on 01 May 1997

[Repair of thoracic and thoracoabdominal aortic aneurisms by the use of hypothermic circulatory arrest]

scientific article published on 01 April 2004

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