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List of works by Nungavarm S. Ramamurthy

A chemically modified nonantimicrobial tetracycline (CMT-8) inhibits gingival matrix metalloproteinases, periodontal breakdown, and extra-oral bone loss in ovariectomized rats

scientific article published on 01 June 1999

A chemically modified tetracycline inhibits streptozotocin-induced diabetic depression of skin collagen synthesis and steady-state type I procollagen mRNA

scientific article published on April 24, 1998

A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats

scientific article published in August 2001

A non-antibacterial chemically-modified tetracycline inhibits mammalian collagenase activity

scientific article published on August 1987

A non-antimicrobial tetracycline inhibits gingival matrix metalloproteinases and bone loss in Porphyromonas gingivalis-induced periodontitis in rats

scientific article published on 01 September 1994

A reassessment of collagen half-life in rat periodontal tissues: application of the pool-expansion approach

scientific article published on 01 July 1986

Alloxan diabetes and reduced bone density in rat mandible

scientific article published on 01 May 1973

Bone cells and matrix bind chemically modified non-antimicrobial tetracycline

scientific article published on 01 May 1994

CMT-8/clodronate combination therapy synergistically inhibits alveolar bone loss in LPS-induced periodontitis

scientific article published on 01 June 1999

CMT/NSAID combination increases bone CMT uptake and inhibits bone resorption.

scientific article

CMT/Tenidap treatment inhibits temporomandibular joint destruction in adjuvant arthritic rats

scientific article published on 01 September 1994

Chemically modified non-antimicrobial tetracyclines inhibit activity of phospholipases A2

scientific article published on 01 September 1998

Chemically modified tetracycline (CMT-8) and estrogen promote wound healing in ovariectomized rats: effects on matrix metalloproteinase-2, membrane type 1 matrix metalloproteinase, and laminin-5 gamma2-chain

scientific article published in January 2002

Chemically-modified tetracycline normalizes collagen metabolism in diabetic rats: a dose-response study

scientific article published on 01 November 1993

Collagenolytic Activity of Crevicular Fluid and of Adjacent Gingival Tissue

scientific article published on November 1, 1979

Collagenolytic activity of crevicular fluid from pericoronal gingival flaps

scientific article published on March 1, 1976

Collagenolytic activity of gingivae from alloxan-diabetic rats

scientific article

Diabetes increases collagenase activity in extracts of rat gingiva and skin

scientific article published on 01 January 1983

Diabetes stimulates procollagen degradation in rat tendon in vitro

scientific article published on 01 February 1986

Doxycycline inhibits neutrophil (PMN)-type matrix metalloproteinases in human adult periodontitis gingiva.

scientific article published on February 1995

Effects of chemically modified tetracycline, CMT-8, on bone loss and osteoclast structure and function in osteoporotic states

scientific article published on 01 June 1999

Effects of ovariectomy on bone morphology in maxillae of mature rats

scientific article published on 01 January 1999

Enhanced Collagenase Activity in Diabetic Rat Gingiva: In Vitro and In Vivo Evidence

scientific article published on March 1, 1978

Excessive matrix metalloproteinase activity in diabetes: inhibition by tetracycline analogues with zinc reactivity

scientific article (publication date: February 2001)

Extensive Degradation of Recently Synthesized Collagen in Gingiva of Normal and Streptozotocin-induced Diabetic Rats

scientific article published on 01 January 1984

Functional sites of chemically modified tetracyclines: inhibition of the oxidative activation of human neutrophil and chicken osteoclast pro-matrix metalloproteinases

scientific article published on 01 May 1998

Further evidence that tetracyclines inhibit collagenase activity in human crevicular fluid and from other mammalian sources

scientific article published on 01 January 1985

Gelatinase A (MMP-2), collagenase-2 (MMP-8), and laminin-5 gamma2-chain expression in murine inflammatory bowel disease (ulcerative colitis)

scientific article published on 01 January 2003

Gelatinases/type IV collagenases in jaw cyst expansion

scientific article published on September 1994

HPLC determination of a chemically modified nonantimicrobial tetracycline: Biological implications

scientific article published on 01 February 1992

Identification and characterization of gelatinases/type IV collagenases in jaw cysts

scientific article published on 01 February 1995

Immunization with Porphyromonas (Bacteroides) gingivalis fimbriae protects against periodontal destruction

scientific article published on July 1, 1992

In Vitro Sensitivity of the Three Mammalian Collagenases to Tetracycline Inhibition: Relationship to Bone and Cartilage Degradation

scientific article published on 01 January 1998

In Vivo Assay of Crevicular Leukocyte Migration: Its Development and Potential Applications

In Vivo Crevicular Leucocyte Response in Humans to a Chemotactic Challenge: Effects of Periodontal Diseases

scientific article published on 01 January 1984

In vivo assay of crevicular leukocyte migration. Its development and potential applications

scientific article

In vivo crevicular leukocyte response to a chemotactic challenge: inhibition by experimental diabetes.

scientific article

Infection with a gram-negative organism stimulates gingival collagenase production in non-diabetic and diabetic germfree rats

scientific article published on 01 July 1988

Inhibition of epiphyseal cartilage collagenase by tetracyclines in low phosphate rickets in rats

scientific article published on 01 January 1988

Inhibition of extracellular release of proinflammatory secretory phospholipase A2 (sPLA2) by sulfasalazine: a novel mechanism of anti-inflammatory activity

scientific article published in June 1997

Inhibition of matrix metalloproteinase-mediated periodontal bone loss in rats: a comparison of 6 chemically modified tetracyclines

scientific article published in July 2002

Inhibition of matrix metalloproteinases by chemically modified tetracyclines in sepsis

scientific article published in September 2003

Inhibition of proteolytic, serpinolytic, and progelatinase-b activation activities of periodontopathogens by doxycycline and the non-antimicrobial chemically modified tetracycline derivatives

scientific article published in January 2002

Insulin reversal of alloxan-diabetes induced changes in gingival collagen metabolism of the rat.

scientific article published in January 1974

Insulin-deficient diabetes impairs osteoblast and periodontal ligament fibroblast metabolism but does not affect ameloblasts and odontoblasts: response to tetracycline(s) administration

scientific article published on 01 September 1990

Leucocyte respones in the gingival crevice of the diabetic rat

scientific article published on July 1, 1979

Local and systemic factors in periodontal disease increase matrix-degrading enzyme activities in rat gingiva: effect of micocycline therapy

scientific article published on 01 March 1996

Long-term therapy with a new chemically modified tetracycline (CMT-8) inhibits bone loss in femurs of ovariectomized rats

scientific article published on 01 November 1998

MMP-mediated events in diabetes

scientific article published on 01 June 1999

Metastatic mouse melanoma cells release collagen-gelatin degrading metalloproteinases as components of shed membrane vesicles

scientific article published in April 1987

Minocycline reduces gingival collagenolytic activity during diabetes. Preliminary observations and a proposed new mechanism of action

scientific article published on 01 September 1983

Modulation of bone resorption by tetracyclines.

scientific article published on September 1994

Parathyroid hormone regulation of matrix degrading enzymes in rat osteoblastic osteosarcoma 17/2.8 cells

scientific article published on March 1, 1992

Periodontopathic potential of two strains of Porphyromonas gingivalis in gnotobiotic rats

scientific article published on October 1, 1992

Purification and characterization of a connective-tissue-degrading metalloproteinase from the cytosol of metastatic melanoma cells

scientific article published on July 1987

Reactive oxygen species activate and tetracyclines inhibit rat osteoblast collagenase

article

Response of rat connective tissues to streptozotocin-diabetes. Tissue-specific effects on collagen metabolism

scientific article published on February 19, 1979

Root-surface caries in rats and humans: inhibition by a non-antimicrobial property of tetracyclines

scientific article published on 01 November 1998

Skin Collagen Metabolism in the Streptozotocin-induced Diabetic Rat: Enhanced Catabolism of Collagen Formed Both Before and During the Diabetic State

scientific article published on 01 May 1982

Some Characteristics of Collagenase Activity in Gingival Crevicular Fluid and Its Relationship to Gingival Diseases in Humans

scientific article published on November 1, 1976

Specificity of the anticollagenase action of tetracyclines: relevance to their anti-inflammatory potential

scientific article published on January 1, 1992

Suppressed collagenolytic activity in polymorphonuclear leucocytes from diabetic humans

scientific article published on March 15, 1981

Tenidap and flurbiprofen enhance uptake of matrix metalloproteinase inhibitor 4-dedimethylaminotetracycline in inflamed joints of adjuvant arthritic rats

scientific article published on 01 September 1995

Tetracycline administration increases collagen synthesis in osteoblasts of streptozotocin-induced diabetic rats: a quantitative autoradiographic study

scientific article published on 01 May 1992

Tetracycline administration increases protein (presumably procollagen) synthesis and secretion in periodontal ligament fibroblasts of streptozotocin-induced diabetic rats

scientific article published on 01 November 1992

Tetracycline administration normalizes the structure and acid phosphatase activity of osteoclasts in streptozotocin-induced diabetic rats

scientific article published on 01 August 1990

Tetracycline administration prevents diabetes-induced osteopenia in the rat: initial observations

scientific article published in April 1990

Tetracycline administration restores osteoblast structure and function during experimental diabetes

scientific article published on September 1, 1991

Tetracycline prevents cancellous bone loss and maintains near-normal rates of bone formation in streptozotocin diabetic rats

scientific article published on 01 August 1997

Tetracycline/flurbiprofen combination therapy modulates bone remodeling in ovariectomized rats: preliminary observations

scientific article published on 01 December 1996

Tetracyclines Inhibit Connective Tissue Breakdown: New Therapeutic Implications for an Old Family of Drugs

scientific article published on January 1, 1991

Tetracyclines Inhibit Tissue Collagenases: Effects of Ingested Low-Dose and Local Delivery Systems

Tetracyclines inhibit Porphyromonas gingivalis-induced alveolar bone loss in rats by a non-antimicrobial mechanism

scientific article published on 01 July 1994

Tetracyclines inhibit human synovial collagenase in vivo and in vitro

scientific article published on 01 February 1987

Tetracyclines inhibit intracellular muscle proteolysis in vitro

scientific article published on October 30, 1992

Tetracyclines inhibit parathyroid hormone-induced bone resorption in organ culture

scientific article published on 01 November 1984

Tetracyclines inhibit protein glycation in experimental diabetes.

scientific article

Tetracyclines inhibit tissue collagenase activity. A new mechanism in the treatment of periodontal disease

scientific article published on 01 November 1984

Tetracyclines inhibit tissue collagenases. Effects of ingested low-dose and local delivery systems

scientific article published on 01 November 1985

Tetracyclines suppress matrix metalloproteinase activity in adjuvant arthritis and in combination with flurbiprofen, ameliorate bone damage

scientific article published on 01 June 1992

The "cyclic" regimen of low-dose doxycycline for adult periodontitis: a preliminary study

scientific article published in May 1996

The Expression of Collagen I and XII mRNAs in Porphyromonas gingivalis‐Induced Periodontitis in Rats: The Effect of Doxycycline and Chemically Modified Tetracycline

scientific article published on 01 January 1998

The development of an altered gingival crevicular microflora in the alloxan-diabetic rat

scientific article published on 01 January 1982

The effect of alloxan diabetes on gingival collagen metabolism in rats

scientific article published on 01 November 1972

The effect of alloxan diabetes on prolyl and lysyl hydroxylase activity in uninflamed and inflamed rat gingiva

scientific article published on 01 January 1985

The effect of experimental diabetes on the molecular characteristics of soluble rat-tail tendon collagen

scientific article published on 01 May 1978

The effect of phenytoin on collagenase and gelatinase activities in UMR 106-01 rat osteoblastic osteosarcoma cells

scientific article published in March 1990

The effect of tetracyclines on collagenase activity in UMR 106-01 rat osteoblastic osteosarcoma cells

scientific article published on 01 December 1990

The in vivo fractional rate of gingival collagen production in non-diabetic and diabetic rats. Application of a novel approach for quantification-pool expansion

scientific article published on 01 January 1986

The nonantimicrobial properties of tetracycline for the treatment of periodontal disease.

scientific article published on January 1994

The potential role of doxycycline in the treatment of osteoarthritis of the temporomandibular joint.

scientific article

The response of human sulcular leucocytes to a chemotactic challenge. A new in vivo assay

scientific article published on 01 March 1981

Tissue healing with doxycycline and chemically modified tetracycline treatments in rats with Porphyromonas gingivalis-induced periodontitis

scientific article published in September 1994

Topically applied CMT-2 enhances wound healing in streptozotocin diabetic rat skin

scientific article published on 01 November 1998

Wound healing in aged normal and ovariectomized rats: effects of chemically modified doxycycline (CMT-8) on MMP expression and collagen synthesis

scientific article published on 01 June 1999