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List of works by Christian Höcht

A highly concentrated and taste-improved aqueous formulation of efavirenz for a more appropriate pediatric management of the anti-HIV therapy

scientific article published in April 2010

Acute effects of third generation β-blockers on short-term and beat-to-beat blood pressure variability in sinoaortic-denervated rats

scientific article published on 31 January 2013

Adenosine A1 receptors and mitochondria: targets of remote ischemic preconditioning

scientific article published on 25 January 2019

Advances in therapy for the prevention of HIV transmission from mother to child

scientific article published on 11 April 2017

Angiotensin-(1-7) protects from brain damage induced by shiga toxin 2-producing enterohemorrhagic Escherichia coli

scientific article published on 28 September 2016

Anterior hypothalamic $beta;-adrenergic activity in the maintenance of hypertension in aortic coarctated rats ⬇️

scientific article published on January 1, 2004

Anterior hypothalamic beta-adrenoceptors in chronic aortic-coarctated hypertensive rats: an interaction with central angiotensin II receptors

scientific article published in January 2005

Applicability of microdialysis as a technique for pharmacokinetic-pharmacodynamic (PK-PD) modeling of antihypertensive beta-blockers

scientific article published in September 2005

Applicability of reverse microdialysis in pharmacological and toxicological studies

scientific article

Application of microdialysis for pharmacokinetic-pharmacodynamic modelling

scientific article published on September 2006

Application of microdialysis in clinical pharmacology

scientific article published on May 2006

Bioavailability of coenzyme Q10 loaded in an oleogel formulation for oral therapy: Comparison with a commercial-grade solid formulation

scientific article published on 10 April 2020

Blood Pressure Variability: Prognostic Value and Therapeutic Implications

Cardiovascular drugs inducing QT prolongation: facts and evidence

scientific article published on January 2010

Centrally administered insulin potentiates the pressor response to angiotensin II.

scientific article published on 28 April 2010

Changes in the in vitro pharmacodynamic properties of metoprolol in atria isolated from spontaneously hypertensive rats

scientific article published on 01 March 2007

Changes in the loading conditions induced by vagal stimulation modify the myocardial infarct size through sympathetic-parasympathetic interactions

scientific article published on 17 August 2014

Chronic infusion of angiotensin-(1-7) improves insulin resistance and hypertension induced by a high-fructose diet in rats

scientific article

Circadian modulation of motivation in mice

scientific article published on 17 January 2020

Comparison of different pharmacodynamic models for PK-PD modeling of verapamil in renovascular hypertension

scientific article published on 19 March 2008

Deficits in temporal processing in mice prenatally exposed to Valproic Acid.

scientific article published on 14 June 2017

Didanosine-loaded poly(epsilon-caprolactone) microparticles by a coaxial electrohydrodynamic atomization (CEHDA) technique

scientific article published on 04 November 2014

Differential hippocampal pharmacokinetics of phenobarbital and carbamazepine in repetitive seizures induced by 3-mercaptopropionic acid.

scientific article published on 4 February 2009

Drugs affecting blood pressure variability: an update

scientific article

Dual role of serotonin in the acquisition and extinction of reward-driven learning: involvement of 5-HT1A, 5-HT2A and 5-HT3 receptors

scientific article published on 17 June 2014

Efavirenz is a substrate and in turn modulates the expression of the efflux transporter ABCG2/BCRP in the gastrointestinal tract of the rat ⬇️

scientific article published on July 23, 2011

Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability [corrected].

scientific article published in January 2010

Effect of nebivolol on beat-to-beat and short-term blood pressure variability in spontaneously hypertensive rats

scientific article published on 09 May 2012

Effects of carvedilol or amlodipine on target organ damage in L-NAME hypertensive rats: their relationship with blood pressure variability

scientific article published on 2 March 2017

Effects of third-generation β-blockers, atenolol or amlodipine on blood pressure variability and target organ damage in spontaneously hypertensive rats

scientific article published on 01 March 2020

Enantioselective pharmacokinetic and pharmacodynamic properties of carvedilol in spontaneously hypertensive rats: focus on blood pressure variability ⬇️

scientific article published on 03 November 2011

Enantioselective pharmacokinetic-pharmacodynamic modelling of carvedilol in a N-nitro-l-arginine methyl ester rat model of secondary hypertension

scientific article published on July 2010

Enantioselective pharmacokinetics and cardiovascular effects of nebivolol in L-NAME hypertensive rats

scientific article published on 17 October 2013

Enhanced oral bioavailability of nevirapine within micellar nanocarriers compared with Viramune(®).

scientific article published on 28 June 2014

Enhanced oral bioavailability of the antiretroviral efavirenz encapsulated in poly(epsilon-caprolactone) nanoparticles by a spray-drying method.

scientific article published on 23 December 2013

Episcleral implants for topotecan delivery to the posterior segment of the eye.

scientific article published on 15 October 2009

Factors influencing hepatic metabolism of antihypertensive drugs: impact on clinical response

scientific article published on 24 December 2018

Fluoxetine potentiation of omega-3 fatty acid antidepressant effect: evaluating pharmacokinetic and brain fatty acid-related aspects in rodents

scientific article published on 29 August 2014

Fructose increases corticosterone production in association with NADPH metabolism alterations in rat epididymal white adipose tissue.

scientific article

Heme oxygenase-1 overexpression fails to attenuate hypertension when the nitric oxide synthase system is not fully operative

scientific article published on 03 June 2011

High fructose diet increases anterior hypothalamic alpha 2-adrenoceptors responsiveness

scientific article published on 01 August 2007

Hypothalamic angiotensinergic-noradrenergic systems interaction in fructose induced hypertension

scientific article published on 29 July 2007

Hypothalamic antihypertensive effect of irbesartan in chronic aortic coarctated rats

scientific article published on 26 November 2004

Hypothalamic antihypertensive effect of metoprolol in chronic aortic coarctated rats

scientific article published in August 2005

Hypothalamic cardiovascular effects of angiotensin-(1-7) in spontaneously hypertensive rats

scientific article published on 5 May 2006

Importance of blood pressure variability in the assessment of cardiovascular risk and benefits of antihypertensive therapy ⬇️

scientific article published on September 1, 2010

In vitro and in vivo pharmacodynamic properties of metoprolol in fructose-fed hypertensive rats

scientific article published in June 2008

In vitro/in vivo characterization of melt-molded gabapentin-loaded poly(epsilon-caprolactone) implants for sustained release in animal studies

scientific article published on 12 June 2008

In vivo and in vitro pharmacodynamic properties of metoprolol in aortic coarctated rats

scientific article published in March 2003

Increased sensitivity to diltiazem hypotensive effect in an experimental model of high-renin hypertension

scientific article published in January 2009

Intranasal administration of antiretroviral-loaded micelles for anatomical targeting to the brain in HIV.

scientific article published on 22 November 2012

Involvement of angiotensin-(1-7) in the hypothalamic hypotensive effect of captopril in sinoaortic denervated rats

scientific article published on 15 August 2007

Involvement of endothelins in deoxycorticosterone acetate-salt hypertension through the modulation of noradrenergic transmission in the rat posterior hypothalamus.

scientific article

Is urethane-chloralose anaesthesia appropriate for pharmacokinetic-pharmacodynamic assessment? Studies with carvedilol

scientific article published in November 2008

Issues in drug metabolism of major antihypertensive drugs: beta-blockers, calcium channel antagonists and angiotensin receptor blockers

scientific article published on February 2010

Measurement of Inverse Agonism in β-Adrenoceptors ⬇️

scientific article published on January 1, 2010

Mechanisms involved in the long-term modulation of tyrosine hydroxylase by endothelins in the olfactory bulb of normotensive rats

scientific journal article

Microdialysis in drug discovery

scientific article

Models for evaluating the pharmacokinetics and pharmacodynamics for β-blockers

scientific article published on 05 March 2014

Myocardial triggers involved in activation of remote ischaemic preconditioning.

scientific article

Neurochemical, Behavioral, and Neurogenic Validation of a Hyposerotonergic Animal Model by Voluntary Oral Consumption of para-Chlorophenylalanine

scientific article published on 09 March 2020

Nicotine-induced molecular alterations are modulated by GABAB receptor activity

scientific article published on 17 April 2017

Nimodipine restores the altered hippocampal phenytoin pharmacokinetics in a refractory epileptic model.

scientific article

Novel carvedilol paediatric nanomicelle formulation: in-vitro characterization and in-vivo evaluation

scientific article published on 19 July 2016

Novel long-term anticonvulsant treatment with gabapentin without causing memory impairment in mice

scientific article published on 15 January 2010

Novel nelfinavir mesylate loaded d-α-tocopheryl polyethylene glycol 1000 succinate micelles for enhanced pediatric anti HIV therapy: In vitro characterization and in vivo evaluation

scientific article published on 22 September 2014

Opposite effects of a single versus repeated doses of gabapentin on retention performance of an inhibitory avoidance response in mice

scientific article published on 20 September 2006

Oral pharmacokinetics of the anti-HIV efavirenz encapsulated within polymeric micelles

scientific article published on 24 December 2010

Paclitaxel-loaded PCL-TPGS nanoparticles: in vitro and in vivo performance compared with Abraxane®.

scientific article published on 5 September 2013

Pharmacokinetic analysis of topotecan after intra-vitreal injection. Implications for retinoblastoma treatment

scientific article published on 20 March 2010

Pharmacokinetic and pharmacodynamic properties of carvedilol in fructose hypertensive rats ⬇️

scientific article published on 05 September 2011

Pharmacokinetic profile of methyldopa in the brain of sinaortic-denervated rats.

scientific article published in July 2003

Pharmacokinetic study of the variability of indinavir drug levels when boosted with ritonavir in HIV-infected children

scientific article published on 4 December 2008

Pharmacokinetic-pharmacodynamic (PK-PD) modeling of cardiovascular effects of metoprolol in spontaneously hypertensive rats: a microdialysis study

scientific article published on 30 May 2006

Pharmacokinetic-pharmacodynamic modeling of diltiazem in spontaneously hypertensive rats: a microdialysis study

scientific article published on 4 May 2007

Pharmacokinetic-pharmacodynamic properties of metoprolol in chronic aortic coarctated rats

scientific article

Pharmacokinetics and the cardiovascular effects of irbesartan in aortic coarctated rats

scientific article

Preischemic efferent vagal stimulation increases the size of myocardial infarction in rabbits. Role of the sympathetic nervous system

scientific article published on 16 January 2012

Recent advances in obesity pharmacotherapy

scientific article published on January 2009

Relationship between P-glycoprotein activity measured in peripheral blood mononuclear cells and indinavir bioavailability in healthy volunteers

scientific article published in January 2009

Relative bioavailability of coenzyme Q10 formulation for paediatric individualized therapy

scientific article published on 27 July 2016

Rifampicin-loaded 'flower-like' polymeric micelles for enhanced oral bioavailability in an extemporaneous liquid fixed-dose combination with isoniazid

scientific article published on 10 January 2014

Role of hypothalamic alpha-adrenoceptor activity in fructose-induced hypertension

scientific article published in October 2006

Role of indoleamine 2,3-dioxygenase in testicular immune-privilege

scientific article published on 04 November 2019

Serotonergic outcome, stress and sexual steroid hormones, and growth in a South American cichlid fish fed with an L-tryptophan enriched diet

scientific article published on 5 October 2015

Sociability deficits after prenatal exposure to valproic acid are rescued by early social enrichment.

scientific article

Spray-dried didanosine-loaded polymeric particles for enhanced oral bioavailability.

scientific article

Study of the hypothalamic angiotensin system in aortic coarctated rats using the reverse microdialysis technique

scientific article

Tetronic® 904-containing polymeric micelles overcome the overexpression of ABCG2 in the blood-brain barrier of rats and boost the penetration of the antiretroviral efavirenz into the CNS.

scientific article published on 7 August 2015

The SSRI fluoxetine exhibits mild effects on the reproductive axis in the cichlid fish Cichlasoma dimerus (Teleostei, Cichliformes).

scientific article published on 25 December 2016

Therapeutic implications of beta-adrenergic receptor pharmacodynamic properties

scientific article published on September 2008

Validation of a new intraarterial microdialysis shunt probe for the estimation of pharmacokinetic parameters

scientific article published in April 2003

What is the Real Efficacy of Beta-Blockers for the Treatment of Essential Hypertension?

scientific article published on 7 June 2017

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