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List of works by David Eastwood

"Cytokine storm" in the phase I trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics

scientific article published on 01 September 2007

An autologous endothelial cell:peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics.

scientific article published on 6 March 2015

Antibody C Region Influences TGN1412-like Functional Activity In Vitro

scientific article published on 12 November 2012

Comparison of novel methods for predicting the risk of pro-inflammatory clinical infusion reactions during monoclonal antibody therapy.

scientific article published on 30 June 2011

Endothelial cells co-stimulate peripheral blood mononuclear cell responses to monoclonal antibody TGN1412 in culture

scientific article published on 13 April 2011

How predictive are in vitro assays for cytokine release syndrome in vivo? A comparison of methods reveals worrying differences in sensitivity and frequency of response.

scientific article published on 30 July 2013

Improved in vitro methods to predict the in vivo toxicity in man of therapeutic monoclonal antibodies including TGN1412

scientific article published on 04 November 2009

Severity of the TGN1412 trial disaster cytokine storm correlated with IL-2 release.

scientific article published on August 2013

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