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List of works by Patrick Y Wen

2016 World Health Organization Classification of Central Nervous System Tumors

scientific article published in December 2017

A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients

scientific article

A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients

scientific article

A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme

scientific article published on 22 September 2006

A Phase II Study of Dose-Dense Temozolomide and Lapatinib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma

scientific article published on 21 October 2020

A Phase Ib/II, open-label, multicenter study of INC280 (capmatinib) alone and in combination with buparlisib (BKM120) in adult patients with recurrent glioblastoma

scientific article published on 27 November 2019

A Quantitative Framework for Modeling COVID-19 Risk During Adjuvant Therapy Using Published Randomized Trials of Glioblastoma in the Elderly

scientific article published on 27 April 2020

A Randomized Double-Blind Placebo-Controlled Phase II Trial of Dendritic Cell Vaccine ICT-107 in Newly Diagnosed Patients with Glioblastoma

scientific article published on 18 July 2019

A clinical perspective on the 2016 WHO brain tumor classification and routine molecular diagnostics

scientific article published on 21 February 2017

A low percentage of metastases in deep brain and temporal lobe structures

scientific article published on 01 May 2019

A novel treatment for glioblastoma: integrin inhibition ⬇️

scientific article published on April 1, 2012

A phase 2 study of the first imipridone ONC201, a selective DRD2 antagonist for oncology, administered every three weeks in recurrent glioblastoma

scientific article published on 12 May 2017

A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study.

scientific article

A phase I study of cediranib in combination with cilengitide in patients with recurrent glioblastoma

scientific article

A phase I trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas.

scientific article

A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma

scientific article

A phase I/II trial of pazopanib in combination with lapatinib in adult patients with relapsed malignant glioma.

scientific article published on 30 January 2013

A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03 ⬇️

scientific article published on March 3, 2011

A phase II study evaluating the efficacy and safety of AMG 102 (rilotumumab) in patients with recurrent glioblastoma ⬇️

scientific article published on February 4, 2011

A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy

scientific article

A phase II trial of oral gimatecan for recurrent glioblastoma

scientific article

A pilot safety study of lenalidomide and radiotherapy for patients with newly diagnosed glioblastoma multiforme

scientific article published on 29 May 2008

A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma

scientific article

A randomized controlled phase III study of VB-111 combined with bevacizumab vs. bevacizumab monotherapy in patients with recurrent glioblastoma (GLOBE)

scientific article published on 17 December 2019

A randomized phase II study of everolimus in combination with chemoradiation in newly diagnosed glioblastoma: Results of NRG Oncology RTOG 0913.

scientific article published on 6 November 2017

A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy

scientific article published on 21 February 2016

ACTR-02. DCC-2618, A NOVEL pan-KIT AND PDGFRa KINASE SWITCH CONTROL INHIBITOR, SHOWS ENCOURAGING SIGNAL IN A PATIENT (PT) WITH GLIOBLASTOMA (GBM)

scientific article published on 6 November 2017

ACTR-14. PHASE I STUDY OF AZD1775 WITH RADIATION THERAPY (RT) AND TEMOZOLOMIDE (TMZ) IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM) AND EVALUATION OF INTRATUMORAL DRUG DISTRIBUTION (IDD) IN PATIENTS WITH RECURRENT GBM

ACTR-15. SAFETY AND PRELIMINARY ACTIVITY OF PT2385, A FIRST-IN-CLASS HIF2-ALPHA INHIBITOR, PLANNED INTERIM ANALYSIS OF AN OPEN LABEL, SINGLE-ARM PHASE II STUDY IN PATIENTS WITH RECURRENT GLIOBLASTOMA

ACTR-17. EVOPHOSPHAMIDE (TH-302) FOR RECURRENT GBM FOLLOWING BEVACIZUMAB FAILURE, FINAL RESULTS OF A MULTICENTER PHASE II STUDY

ACTR-18. PHASE II TRIAL OF TEMOZOLOMIDE AND TRC 102, BASE EXCISION REPAIR INHIBITOR, IN BEVACIZUMAB NAÏVE GLIOBLASTOMA AT FIRST RECURRENCE

ACTR-30. PHASE 1B/2 STUDY TO ASSESS THE CLINICAL EFFECTS OF PAMIPARIB (BGB-290) IN COMBINATION WITH RADIATION THERAPY (RT) AND/OR TEMOZOLOMIDE (TMZ) IN PATIENTS WITH NEWLY DIAGNOSED OR RECURRENT/REFRACTORY GLIOBLASTOMA (GBM)

ACTR-31. PHASE 1 STUDY OF AG-881, AN INHIBITOR OF MUTANT IDH1 AND IDH2: RESULTS FROM THE RECURRENT/PROGRESSIVE GLIOMA POPULATION

ACTR-33. TUMOR TISSUE PENETRATION AND PHARMACODYNAMICS OF ONC201 IN ADULT RECURRENT GLIOBLASTOMA PATIENTS

ACTR-34. INTEGRATED CLINICAL EXPERIENCE WITH ONC201 IN PREVIOUSLY-TREATED H3 K27M-MUTANT GLIOMA PATIENTS

ACTR-46. AG-120, A FIRST-IN-class MUTANT IDH1 INHIBITOR IN PATIENTS WITH RECURRENT OR PROGRESSIVE IDH1 MUTANT GLIOMA: UPDATED RESULTS FROM THE PHASE 1 NON-ENHANCING GLIOMA POPULATION.

scientific article published on 6 November 2017

ACTR-51. CLINICAL EVALUATION OF THE IMIPRIDONE ONC201 IN RECURRENT GLIOBLASTOMA: PREDICTIVE AND PHARMACODYNAMIC BIOMARKER ANALYSES

ACTR-51. PHASE 2 STUDY TO EVALUATE THE SAFETY, PHARMACOKINETICS AND CLINICAL ACTIVITY OF PI3K/MTOR INHIBITOR GDC-0084 GIVEN TO GLIOBLASTOMA (GBM) PATIENTS WITH UNMETHYLATED O6-METHYLGUANINE-METHYLTRANSFERASE PROMOTER STATUS

scientific article published on 5 November 2018

ACTR-74. A PHASE IB/II, OPEN-LABEL, MULTICENTER STUDY OF CAPMATINIB (INC280) ALONE AND IN COMBINATION WITH BUPARLISIB (BKM120) IN ADULT PATIENTS WITH RECURRENT GLIOBLASTOMA

ACTR-76. FINAL RESULTS FROM A PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA.

scientific article published on 6 November 2017

ACTR-93. A PHASE I STUDY OF MLN0128 (TAK-228) AND BEVACIZUMAB IN PATIENTS WITH ADVANCED SOLID TUMORS INCLUDING GLIOBLASTOMA

ACTR-95. HYPOXIA ACTIVATED EVOPHOSPHAMIDE (TH-302) FOR RECURRENT GBM FOLLOWING BEVACIZUMAB FAILURE, A MULTICENTER PHASE II STUDY

AT-07A PHASE II STUDY OF LAPATINIB AND DOSE-DENSE TEMOZOLOMIDE (TMZ) FOR ADULTS WITH RECURRENT EPENDYMOMA: PATIENT REPORTED OUTCOMES (PRO) FROM A CERN CLINICAL TRIAL.

scientific article published in November 2014

AT-16PHASE II STUDY OF TIVOZANIB, AN ORAL VEGFR INHIBITOR, IN PATIENTS WITH RECURRENT GLIOBLASTOMA

AT-23A PHASE II STUDY OF LAPATINIB AND DOSE-DENSE TEMOZOLOMIDE (TMZ) FOR ADULTS WITH RECURRENT EPENDYMOMA: A CERN CLINICAL TRIAL

AT-36PANOBINOSTAT IN COMBINATION WITH BEVACIZUMAB FOR RECURRENT GLIOBLASTOMA AND ANAPLASTIC GLIOMA

AT-37PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA.

scientific article published in November 2014

AT-60A RANDOMIZED DOUBLE BLIND PLACEBO-CONTROLLED PHASE 2 TRIAL OF DENDRITIC CELL (DC) VACCINE ICT-107 FOLLOWING STANDARD TREATMENT IN NEWLY DIAGNOSED PATIENTS WITH GBM.

scientific article

ATCT-22NRG ONCOLOGY/RTOG 1122: PHASE II DOUBLE-BLINDED, PLACEBO-CONTROLLED STUDY OF BEVACIZUMAB WITH OR WITHOUT AMG 386 IN PATIENTS WITH RECURRENT GLIOBLASTOMA OR GLIOSARCOMA.

scientific article

ATIM-03. BIOMARKER ANALYSIS SUPPORTS THE VB-111 DUAL MECHANISM OF ACTION

ATIM-12. NEOADJUVANT ANTI-PD-1 IMMUNOTHERAPY PROMOTES INTRATUMORAL AND SYSTEMIC IMMUNE RESPONSES IN RECURRENT GLIOBLASTOMA: AN IVY CONSORTIUM TRIAL

ATIM-19. RESULTS OF THE GLOBE STUDY: A PHASE 3, RANDOMIZED, CONTROLLED, DOUBLE-ARM, OPEN-LABEL, MULTI-CENTER STUDY OF VB-111 COMBINED WITH BEVACIZUMAB VS. BEVACIZUMAB MONOTHERAPY IN PATIENTS WITH RECURRENT GLIOBLASTOMA

ATIM-21. UPDATED RESULTS OF A PHASE I TRIAL OF ANTI-LAG-3 OR ANTI-CD137 ALONE AND IN COMBINATION WITH ANTI-PD-1 IN PATIENTS WITH RECURRENT GBM

ATIM-23. PHASE I TRIAL OF ANTI-LAG-3 OR ANTI-CD137 ALONE AND IN COMBINATION WITH ANTI-PD-1 IN PATIENTS WITH RECURRENT GBM

scientific article published on 6 November 2017

ATIM-29. NRG BN002: SAFETY DATA FROM A PHASE I STUDY OF IPILIMUMAB (IPI), NIVOLUMAB (NIVO), AND THE COMBINATION FOR NEWLY DIAGNOSED GLIOBLASTOMA (GBM)

ATIM-32. PERSONALIZED NEOANTIGEN-TARGETING VACCINE GENERATES ROBUST SYSTEMIC AND INTRATUMORAL T CELL RESPONSES IN GLIOBLASTOMA (GBM) PATIENTS

ATNT-12PHASE I, TWO-STAGE, OPEN-LABEL, DOSE-ESCALATION STUDY OF BUPARLISIB (BKM120) IN COMBINATION WITH ADJUVANT TEMOZOLOMIDE (TMZ) AND WITH CONCOMITANT RADIATION THERAPY (RT) AND TMZ IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM).

scientific article

ATNT-14PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA.

scientific article

ATNT-17 EVALUATION OF THE SAFETY AND BENEFIT OF PHASE I ONCOLOGY TRIALS FOR PATIENTS WITH PRIMARY CENTRAL NERVOUS SYSTEM TUMORS

scientific article

ATNT-18A PHASE I STUDY OF MLN0128 AND BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA AND OTHER SOLID TUMORS.

scientific article

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

scientific article

Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE.

scientific article published on 16 August 2017

Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma

scientific article

Advances in meningioma therapy

scientific article published on May 2009

Advances in multidisciplinary therapy for meningiomas

scientific article published on 01 January 2019

An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway

scientific article published on 15 September 2011

An exploratory survival analysis of anti-angiogenic therapy for recurrent malignant glioma

scientific article

An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma ⬇️

scientific article published on June 1, 2013

Angiogenesis inhibitors in tackling recurrent glioblastoma

scientific article

Antiangiogenic (metronomic) chemotherapy for brain tumors: current and future perspectives.

scientific article published on July 2009

Antiangiogenic strategies for treatment of malignant gliomas ⬇️

scientific article published on July 2009

Antiangiogenic therapies for high-grade glioma

scientific article published on 13 October 2009

Antiangiogenic therapy for patients with glioblastoma: current challenges in imaging and future directions

scientific article published in May 2011

Antiangiogenic therapy in malignant gliomas

scientific article

Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: a multi-center study

scientific article

Application of novel response/progression measures for surgically delivered therapies for gliomas: Response Assessment in Neuro-Oncology (RANO) Working Group

scientific article

Author response

Automatic assessment of glioma burden: a deep learning algorithm for fully automated volumetric and bidimensional measurement

scientific article published on 01 November 2019

BMET-26PHASE 2 STUDY OF VB-111, AN ANTI-CANCER GENE THERAPY, AS MONOTHERAPY FOLLOWED BY COMBINATION OF VB-111 WITH BEVACIZUMAB, IN PATIENTS WITH RECURRENT GLIOBLASTOMA.

scientific article

Barriers to Accrual and Enrollment in Brain Tumor Trials

scientific article published on 07 June 2019

Baseline Requirements for Novel Agents Being Considered for Phase II/III Brain Cancer Efficacy Trials:Conclusions from the Adult Brain Tumor Consortium's First Workshop on CNS Drug Delivery

scientific article published on 07 June 2020

Baseline pretreatment contrast enhancing tumor volume including central necrosis is a prognostic factor in recurrent glioblastoma: evidence from single and multicenter trials

scientific article

Bayesian Adaptive Randomized Trial Design for Patients With Recurrent Glioblastoma ⬇️

scientific article published on May 29, 2012

Bevacizumab and glioblastoma: scientific review, newly reported updates, and ongoing controversies

scientific article published on 26 September 2014

Bevacizumab for glioblastoma: what can we learn from patterns of progression?

scientific article

Bevacizumab salvage therapy following progression in high-grade glioma patients treated with VEGF receptor tyrosine kinase inhibitors

scientific article

Biological activity of weekly ONC201 in adult recurrent glioblastoma patients

scientific article published on 01 January 2020

Brain Malignancy Steering Committee clinical trials planning workshop: report from the Targeted Therapies Working Group

scientific article

Brain Metastases in Newly Diagnosed Breast Cancer: A Population-Based Study.

scientific article

Brain metastases

scientific article published on 01 December 2005

Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial

scientific article published on 04 February 2019

CNS Anticancer Drug Discovery and Development Conference White Paper.

scientific article

CNS Hodgkin lymphoma

scientific article

Case Report: Next generation sequencing identifies a NAB2-STAT6 fusion in Glioblastoma

scientific article published on 27 January 2016

Central Nervous System Complications of Cancer Therapy ⬇️

scientific article published on April 27, 2012

Cerebrospinal fluid spread of anaplastic glioma

scientific article published in February 2007

Challenges relating to solid tumour brain metastases in clinical trials, part 1: patient population, response, and progression. A report from the RANO group.

scientific article

Challenges relating to solid tumour brain metastases in clinical trials, part 2: neurocognitive, neurological, and quality-of-life outcomes. A report from the RANO group.

scientific article published on September 2013

Challenges with defining response to antitumor agents in pediatric neuro-oncology: A report from the response assessment in pediatric neuro-oncology (RAPNO) working group

article

Chemotherapy and targeted molecular therapies for brain metastases

scientific article published on October 2006

Chemotherapy for low-grade gliomas: emerging consensus on its benefits.

scientific article

Cilengitide in patients with recurrent glioblastoma: the results of NABTC 03-02, a phase II trial with measures of treatment delivery ⬇️

scientific article published on July 8, 2011

Clinical Importance of CDKN2A Loss and Monosomy 10 in Pilocytic Astrocytoma

scientific article published on 23 May 2019

Clinical Relevance of Steroid Use in Neuro-Oncology

scientific article

Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma

scientific article

Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas

scientific article published on September 2014

Clinical pharmacokinetics and pharmacodynamics of ivosidenib, an oral, targeted inhibitor of mutant IDH1, in patients with advanced solid tumors

scientific article published on 26 April 2019

Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group.

scientific article published in January 2018

Clinical trial design for systemic agents in patients with brain metastases from solid tumours: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group.

scientific article published in January 2018

Clinical trial end points for high-grade glioma: the evolving landscape.

scientific article published on 09 February 2011

Colon perforation during antiangiogenic therapy for malignant glioma

scientific article published on 29 August 2008

Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma

scientific article

Combining progression-free survival and overall survival as a novel composite endpoint for glioblastoma trials

scientific article published on 7 January 2015

Comparison of linear and volumetric criteria in assessing tumor response in adult high-grade gliomas

scientific article published on January 2006

Consensus Recommendations for a Dynamic Susceptibility Contrast MRI Protocol for Use in High-Grade Gliomas

scientific article published on 09 June 2020

Consensus recommendations for a standardized Brain Tumor Imaging Protocol in clinical trials

scientific article (publication date: September 2015)

Consensus recommendations for a standardized brain tumor imaging protocol for clinical trials in brain metastases (BTIP-BM)

scientific article published on 12 February 2020

Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2

article

Corticosteroid Use in Patients with Glioblastoma at First or Second Relapse Treated with Bevacizumab in the BRAIN Study ⬇️

scientific article published on December 8, 2010

Corticosteroid use endpoints in neuro-oncology: Response Assessment in Neuro-Oncology Working Group

scientific article published on 01 June 2018

Corticosteroids for peritumoral edema: time to overcome our addiction?

scientific article published on 16 August 2016

CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans

scientific article published on 01 September 2008

Current and future directions for Phase II trials in high-grade glioma ⬇️

scientific article published on April 1, 2013

Current clinical development of PI3K pathway inhibitors in glioblastoma ⬇️

scientific article published on May 22, 2012

Current status of antiangiogenic therapies for glioblastomas

scientific article published on 10 December 2013

Cytokines associated with toxicity in the treatment of recurrent glioblastoma with aflibercept

scientific article published on 24 January 2013

Cytotoxic chemotherapeutic management of newly diagnosed glioblastoma multiforme

scientific article published on 20 August 2008

DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues

scientific article

DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor

scientific article

Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600-Mutant Anaplastic Thyroid Cancer

scientific article published on 26 October 2017

Dabrafenib plus trametinib in patients with BRAFV600E-mutated biliary tract cancer (ROAR): a phase 2, open-label, single-arm, multicentre basket trial

scientific article published on 17 August 2020

Demonstration of DCE-MRI as an early pharmacodynamic biomarker of response to VEGF Trap in glioblastoma

scientific article

Diagnostic Accuracy of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy in Newly-Diagnosed Brain Mass and Suspected Recurrent Gliomas

scientific article published on 9 February 2018

Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors

scientific article

Diffusion MRI Phenotypes Predict Overall Survival Benefit from Anti-VEGF Monotherapy in Recurrent Glioblastoma: Converging Evidence from Phase II Trials.

scientific article

Discontinuing bevacizumab in patients with glioblastoma: an ethical analysis

scientific article published on 23 September 2011

Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas

scientific article published on 01 September 2020

Dopamine Receptor D5 is a Modulator of Tumor Response to Dopamine Receptor D2 Antagonism

scientific article published on 17 December 2018

Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate.

scientific article published on 10 October 2016

EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy

scientific article

EXTH-42. H3 K27M MUTANT GLIOMAS ARE SELECTIVELY KILLED BY ONC201, A SMALL MOLECULE INHIBITOR OF DOPAMINE RECEPTOR D2

scientific article published on 6 November 2017

Early changes in glioblastoma metabolism measured by MR spectroscopic imaging during combination of anti-angiogenic cediranib and chemoradiation therapy are associated with survival.

scientific article published on 12 June 2017

Effect of adding temozolomide to radiation therapy on the incidence of pseudo-progression

scientific article published on 17 February 2009

Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors

scientific article published on 23 May 2016

Emerging antiangiogenic treatments for gliomas - efficacy and safety issues

scientific article published on December 2008

End point assessment in gliomas: novel treatments limit usefulness of classical Macdonald's Criteria

scientific article

Enhancing radiation therapy for patients with glioblastoma ⬇️

scientific article published on May 1, 2013

Epidemiology of brain metastases

scientific article published in February 2012

Evaluation of RAPNO criteria in medulloblastoma and other leptomeningeal seeding tumors using MRI and clinical data

scientific article published on 26 March 2020

Evaluation of the Safety and Benefit of Phase I Oncology Trials for Patients With Primary CNS Tumors.

scientific article published on 17 August 2015

Evidence and Context of Use for Contrast Enhancement as a Surrogate of Disease Burden and Treatment Response in Malignant Glioma

scientific article

Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma

scientific article

Exploring Predictors of Response to Dacomitinib in EGFR-Amplified Recurrent Glioblastoma

scientific article published on 08 June 2020

Extent of resection and overall survival for patients with atypical and malignant meningioma

scientific article published on 26 August 2015

Facing the future of brain tumor clinical research

scientific article

Feasibility, phase I, and phase II studies of tandutinib, an oral platelet-derived growth factor receptor-β tyrosine kinase inhibitor, in patients with recurrent glioblastoma

scientific article published on 23 September 2016

First-in-Human Phase I Study to Evaluate the Brain-Penetrant PI3K/mTOR Inhibitor GDC-0084 in Patients with Progressive or Recurrent High-Grade Glioma

scientific article published on 14 January 2020

Gender and sex disparity in cancer trials

scientific article published on 01 August 2020

Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas

scientific article published on 9 November 2016

Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model

scientific article published on 6 November 2015

Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions

scientific article published on 24 April 2020

Glioblastoma multiforme: an emerging paradigm of anti-VEGF therapy

scientific article published on 01 April 2008

Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape

scientific article

Glioma in 2014: unravelling tumour heterogeneity-implications for therapy

scientific article published on 06 January 2015

Glioma patient-reported outcome assessment in clinical care and research: a Response Assessment in Neuro-Oncology collaborative report

scientific article published on 01 February 2020

Glioma progression through synaptic activity

scientific article published on 01 January 2020

Glioma.

scientific article published on 16 July 2015

Graft-versus-host disease of the CNS after allogeneic bone marrow transplantation

scientific article published on 10 August 2009

HOUT-15. BRAIN TUMOR PATIENT AND CAREGIVER SURVEY ON CLINICAL TRIALS: IDENTIFYING ATTITUDES AND BARRIERS TO PATIENT PARTICIPATION

article published in 2017

HOUT-28. OFF-LABEL USE OF PD-1 BLOCKADE WITH OR WITHOUT BEVACIZUMAB CONFERS ONLY LIMITED CLINICAL BENEFIT IN PATIENTS WITH RECURRENT HIGH-GRADE GLIOMA

Highlights from the Literature

scientific article published in April 2014

Highlights from the Literature

Highlights from the Literature

Highlights of the 2019 Society for Neuro-Oncology Inaugural Brain Metastases Conference: establishing a dedicated meeting to address an unmet need in the field

scientific article published on 28 January 2020

Histogram analysis of apparent diffusion coefficient within enhancing and nonenhancing tumor volumes in recurrent glioblastoma patients treated with bevacizumab

scientific article

Historical benchmarks for medical therapy trials in surgery- and radiation-refractory meningioma: a RANO review

scientific article

How can we develop therapies for glioblastoma more efficiently? Randomized versus single-arm studies

scientific article

How treatment monitoring is influencing treatment decisions in glioblastomas

scientific article

Hypofractionated versus standard radiation therapy with or without temozolomide for older glioblastoma patients

scientific article published on April 2015

IMCT-20ASSOCIATION OF SURVIVAL AND PROGRESSION-FREE SURVIVAL WITH IMMUNE RESPONSE IN HLA-A2+ NEWLY-DIAGNOSED GBM PATIENTS IN RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED PHASE 2 TRIAL OF DENDRITIC CELL (DC) IMMUNOTHERAPY WITH ICT-107.

scientific article

INCREASED PERFUSION DUE TO VASCULAR NORMALIZATION IMPROVES OXYGENATION AND SURVIVAL IN GLIOBLASTOMA PATIENTS TREATED WITH CEDIRANIB WITH OR WITHOUT CHEMORADIATION.

scientific article published in July 2014

INNV-13. ALLELE: A CONSORTIUM FOR PROSPECTIVE GENOMICS AND FUNCTIONAL DIAGNOSTICS TO GUIDE PATIENT CARE AND TRIAL ANALYSIS IN NEWLY-DIAGNOSED GLIOBLASTOMA

Imaging and diagnostic advances for intracranial meningiomas

scientific article published on 01 January 2019

Imaging of Central Nervous System Tumors Based on the 2016 World Health Organization Classification

scientific article published on 07 November 2019

Immunomodulation for glioblastoma

scientific article

Immunotherapy advances for glioblastoma

scientific article

Immunotherapy response assessment in neuro-oncology: a report of the RANO working group

scientific article

Impact of pemetrexed on intracranial disease control and radiation necrosis in patients with brain metastases from non-small cell lung cancer receiving stereotactic radiation

scientific article published on 2 February 2018

Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation.

scientific article

Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: A population-based study

scientific article published on 24 April 2017

Incidence, risk factors, and reasons for hospitalization among glioblastoma patients receiving chemoradiation

scientific article

Increase of pseudoprogression and other treatment related effects in low-grade glioma patients treated with proton radiation and temozolomide

scientific article published on 28 November 2018

Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion.

scientific article published on 29 November 2011

Individualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT): A Bayesian Adaptive Platform Trial to Develop Precision Medicines for Patients With Glioblastoma

scientific article published on 27 March 2019

Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib

scientific article

Inhibition of angiogenesis and invasion in malignant gliomas

scientific article

Initial treatment patterns over time for anaplastic oligodendroglial tumors ⬇️

scientific article published on May 31, 2012

International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors

scientific article

Is it time to reconsider the role of irinotecan for the treatment of high-grade gliomas?

scientific article published on 01 July 2018

Is surgery at progression a prognostic marker for improved 6-month progression-free survival or overall survival for patients with recurrent glioblastoma?

scientific article

It Is Time to Include Patients With Brain Tumors in Phase I Trials in Oncology ⬇️

scientific article published on July 18, 2011

Ivosidenib in Isocitrate Dehydrogenase 1-Mutated Advanced Glioma

scientific article published on 12 June 2020

Leptomeningeal metastases: a RANO proposal for response criteria.

scientific article

Leptomeningeal metastasis: a Response Assessment in Neuro-Oncology critical review of endpoints and response criteria of published randomized clinical trials

scientific article

Letter: When Less is More: Dexamethasone Dosing for Brain Tumors

scientific article published on 01 September 2019

Leveraging molecular datasets for biomarker-based clinical trial design in glioblastoma.

scientific article published on 20 February 2017

Liquid biopsy in central nervous system metastases: a RANO review and proposals for clinical applications

Local control after brain-directed radiation in patients with cystic versus solid brain metastases

scientific article published on 04 February 2019

Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas

scientific article published on 19 January 2011

Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation

scientific article

MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

scientific article published on 9 May 2016

MNGO-01A PROGNOSTIC CYTOGENETIC SCORING SYSTEM TO GUIDE THE ADJUVANT MANAGEMENT OF PATIENTS WITH ATYPICAL MENINGIOMA.

scientific article

MNGO-04PHASE II TRIAL OF BEVACIZUMAB IN PATIENTS WITH SURGERY AND RADIATION REFRACTORY PROGRESSIVE MENINGIOMA.

scientific article

Malignant gliomas

scientific article published on 01 May 2004

Malignant gliomas: strategies to increase the effectiveness of targeted molecular treatment

scientific article

Management of treatment-associated toxicites of anti-angiogenic therapy in patients with brain tumors.

scientific article

Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities.

scientific article published on 17 November 2006

Mechanisms and therapeutic implications of hypermutation in gliomas

scientific article published on 15 April 2020

Medical management of brain tumor patients

scientific article

Medical management of brain tumors and the sequelae of treatment

scientific article

Medical management of patients with brain tumors

scientific article published on 29 June 2006

Medical therapies for meningiomas ⬇️

scientific article published on 04 September 2010

Meeting Update-Society for Neuro-Oncology 2017 Annual Meeting.

scientific article published in January 2018

Melanoma central nervous system metastases: current approaches, challenges, and opportunities

scientific article published on 12 September 2016

Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review

scientific article

Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade

scientific article published on 27 November 2018

Modified Criteria for Radiographic Response Assessment in Glioblastoma Clinical Trials

scientific article

Molecular and translational advances in meningiomas

scientific article published on 01 January 2019

Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01.

scientific article published in November 2005

Molecular targeted therapy of glioblastoma

scientific article published on 11 September 2019

Morphological characteristics of brain tumors causing seizures

scientific article

Multi-parametric MR-PET imaging predicts pharmacokinetics and clinical response to GDC-0084 in patients with recurrent high-grade glioma

scientific article published on 08 April 2020

Multicenter phase 2 study of patupilone for recurrent or progressive brain metastases from non-small cell lung cancer

scientific article published on 26 August 2015

Multicenter phase II study of rituximab and temozolomide in recurrent primary central nervous system lymphoma ⬇️

scientific article published on July 9, 2012

Multimodal MRI features predict isocitrate dehydrogenase genotype in high-grade gliomas

scientific article published on 26 June 2016

Multimodal imaging patterns predict survival in recurrent glioblastoma patients treated with bevacizumab.

scientific article published on 4 May 2016

Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept

scientific article

NI-36VALIDATION OF RANO CRITERIA: CONTRIBUTION OF T2/FLAIR ASSESSMENT IN PATIENTS WITH RECURRENT GLIOBLASTOMA TREATED WITH BEVACIZUMAB.

scientific article published in November 2014

NIMG-01. DIFFUSION MRI PHENOTYPES PREDICT OVERALL SURVIVAL BENEFIT FROM ANTI-VEGF MONOTHERAPY IN GLIOBLASTOMA AT FIRST OR SECOND RELAPSE

scientific article published on 6 November 2017

NIMG-50. VOLUMETRIC ANALYSIS OF IDH-MUTANT LOW-GRADE GLIOMA: A NATURAL HISTORY STUDY OF TUMOR GROWTH RATES BEFORE AND AFTER TREATMENT

NIMG-53. POST-SURGICAL, RESIDUAL ENHANCING TUMOR VOLUME IS PROGNOSTIC FOR OVERALL SURVIVAL IN NEWLY DIAGNOSED GLIOBLASTOMA: EVIDENCE FROM 1,458 PATIENTS POOLED FROM INTERNATIONAL TRIALS, SINGLE INSTITUTION DATABASES, AND MULTICENTER CONSORTIUMS

NIMG-56IMMUNOTHERAPY RESPONSE ASSESSMENT IN NEURO-ONCOLOGY (iRANO): A REPORT OF THE RANO WORKING GROUP.

scientific article

NIMG-68. MRI CHANGES IN NEWLY DIAGNOSED GLIOBLASTOMA PATIENTS TREATED AS PART OF A PHASE II TRIAL WITH BAVITUXIMAB, RADIATION, AND TEMOZOLOMIDE

NIMG-84. TUMOR LOCATION IS PROGNOSTIC FOR OVERALL SURVIVAL IN NEWLY DIAGNOSED GLIOBLASTOMA: EVIDENCE FROM 1,458 PATIENTS POOLED FROM INTERNATIONAL TRIALS, SINGLE INSTITUTION DATABASES, AND MULTICENTER CONSORTIUMS

NIMG-98. ASSESSMENT OF TUMOR HYPOXIA AND PERFUSION IN GBM FOLLOWING BEV FAILURE USING FMISO 18F-PET AND MRI.

scientific article published on 6 November 2017

NRG/RTOG 1122: A phase 2, double-blinded, placebo-controlled study of bevacizumab with and without trebananib in patients with recurrent glioblastoma or gliosarcoma

scientific article published on 10 March 2020

NT-07PHASE 1-2 DOSE-ESCALATION STUDY OF VB-111, AN ANTI-ANGIOGENIC GENE THERAPY, AS MONOTHERAPY AND IN COMBINATION WITH BEVACIZUMAB, IN PATIENTS WITH RECURRENT GLIOBLASTOMA

scientific article published in November 2014

NTOX-06. INCREASE OF PSEUDOPROGRESSION AND TREATMENT RELATED EFFECTS IN LOW-GRADE GLIOMA PATIENTS TREATED WITH PROTON RADIATION AND TEMOZOLOMIDE

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

article

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

scientific article published on 19 December 2018

Neuro-oncology Management During the COVID-19 Pandemic With a Focus on WHO Grade III and IV Gliomas

scientific article published on 05 May 2020

Neuro-oncology in 2015: Progress in glioma diagnosis, classification and treatment

scientific article

Neurocognitive function in patients with recurrent glioblastoma treated with bevacizumab ⬇️

scientific article published on May 9, 2011

Neurologic Complications of Cranial Radiation Therapy and Strategies to Prevent or Reduce Radiation Toxicity

scientific article published on 29 June 2020

Neurologic complications of cancer drug therapies

scientific article published on April 2012

Neurologic complications of cancer therapy ⬇️

scientific article published on February 1, 2003

Neurological adverse effects caused by cytotoxic and targeted therapies.

scientific article

Neurooncology clinical trial design for targeted therapies: lessons learned from the North American Brain Tumor Consortium.

scientific article published on 17 June 2008

Non-cytotoxic drugs as potential treatments for gliomas

scientific article

Novel Therapies for Glioblastoma

scientific article published on 22 May 2020

Novel anti-angiogenic therapies for malignant gliomas

scientific article published on December 2008

Novel chemotherapeutic approaches in adult high-grade gliomas

scientific article

Novel therapies for malignant gliomas

scientific article

Novel therapies for meningiomas

scientific article published on October 2006

O7.01RESPONSE ASSESSMENT IN NEURO-ONCOLOGY (RANO) CRITERIA FOR BRAIN METASTASES.

scientific article published in September 2014

Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma

scientific article published on 28 January 2016

One size should not fit all: advancing toward personalized glioblastoma therapy

scientific article (publication date: June 2015)

Optimizing eligibility criteria and clinical trial conduct to enhance clinical trial participation for primary brain tumor patients

scientific article published on 24 January 2020

Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study

scientific article published on 8 October 2015

Outcomes after discontinuation of antiepileptic drugs after surgery in patients with low grade brain tumors and meningiomas

scientific article published on 03 January 2012

PATH-16. MOLECULAR PATHOLOGY AND CLINICAL CHARACTERISTICS OF MMR DEFICIENCY (MMRd) IN DIFFUSE GLIOMAS

PCV for anaplastic oligodendrogliomas: back to the future or a step backwards? A point/counterpoint discussion

scientific article

PD-1 inhibition has only limited clinical benefit in patients with recurrent high-grade glioma

scientific article published on 31 August 2018

PDTM-06. ALK AMPLIFICATION AND REARRANGEMENTS ARE RECURRENT TARGETABLE EVENTS IN GLIOBLASTOMA

scientific article published on 5 November 2018

PHASE II TRIAL OF THE PHOSPHATIDYINOSITOL-3 KINASE (PI3K) INHIBITOR BUPARLISIB (BKM120) IN RECURRENT GLIOBLASTOMA CONDUCTED BY THE IVY FOUNDATION EARLY PHASE CLINICAL TRIALS CONSORTIUM.

scientific article published in July 2014

Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201

scientific article published on 27 August 2019

Pharmacodynamics of mutant-IDH1 inhibitors in glioma patients probed by in vivo 3D MRS imaging of 2-hydroxyglutarate.

scientific article published on 16 April 2018

Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma.

scientific article

Phase 0 and Window of Opportunity Clinical Trial Design in Neuro-Oncology: A RANO Review

scientific article published on 29 June 2020

Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas

scientific article

Phase 1 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study

scientific article

Phase 2 and biomarker study of trebananib, an angiopoietin-blocking peptibody, with and without bevacizumab for patients with recurrent glioblastoma.

scientific article published on 19 December 2017

Phase 2 study of bosutinib, a Src inhibitor, in adults with recurrent glioblastoma.

scientific article

Phase 2 study of dose-intense temozolomide in recurrent glioblastoma

scientific article

Phase 2 trial design in neuro-oncology revisited: a report from the RANO group

scientific article published on May 2012

Phase I Study of GRN1005 in Recurrent Malignant Glioma ⬇️

scientific article published on January 24, 2013

Phase I and biomarker study of plerixafor and bevacizumab in recurrent high-grade glioma.

scientific article

Phase I dose-escalation study of the PI3K/mTOR inhibitor voxtalisib (SAR245409, XL765) plus temozolomide with or without radiotherapy in patients with high-grade glioma

scientific article

Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors

scientific article published on 30 April 2012

Phase I study of sorafenib and tipifarnib for recurrent glioblastoma: NABTC 05-02.

scientific article published on 7 October 2017

Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study

scientific article

Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma

scientific article

Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03.

scientific article

Phase I trial of aflibercept (VEGF trap) with radiation therapy and concomitant and adjuvant temozolomide in patients with high-grade gliomas

scientific article

Phase I trial of tipifarnib in patients with recurrent malignant glioma taking enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.

scientific article

Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide ⬇️

scientific article published on September 7, 2010

Phase I/II Trial of Vorinostat Combined with Temozolomide and Radiation Therapy for Newly Diagnosed Glioblastoma: Final Results of Alliance N0874/ABTC 02.

scientific article published on 22 August 2017

Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02

scientific article published on 26 January 2014

Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08.

scientific article published in August 2006

Phase I/II study of sorafenib in combination with erlotinib for recurrent glioblastoma as part of a 3-arm sequential accrual clinical trial: NABTC 05-02

scientific article published on 01 January 2020

Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02.

scientific article

Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs.

scientific article

Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme.

scientific article published in August 2005

Phase II study of Gleevec® plus hydroxyurea (HU) in adults with progressive or recurrent meningioma

scientific article published on 22 September 2011

Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study

scientific article

Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients naive to antiangiogenic therapy

scientific article published on 14 August 2017

Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients with prior antiangiogenic therapy

scientific article published on 3 October 2017

Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma

scientific article

Phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium study

scientific article

Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08).

scientific article

Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults.

scientific article

Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma

scientific article

Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma

scientific article

Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults

scientific article

Phase II study of tivozanib, an oral VEGFR inhibitor, in patients with recurrent glioblastoma.

scientific article published on 16 November 2016

Phase II trial of ponatinib in patients with bevacizumab-refractory glioblastoma

scientific article published on 24 August 2019

Phase II trial of sunitinib for recurrent and progressive atypical and anaplastic meningioma.

scientific article

Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas

scientific article

Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.

scientific article published in August 2006

Phase II trial of triple tyrosine kinase receptor inhibitor nintedanib in recurrent high-grade gliomas.

scientific article published on 22 October 2014

Phase II trials of erlotinib or gefitinib in patients with recurrent meningioma.

scientific article published on 28 June 2009

Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study

scientific article published on 11 August 2007

Pitfalls in the neuroimaging of glioblastoma in the era of antiangiogenic and immuno/targeted therapy - detecting illusive disease, defining response

scientific article

Polysomy for chromosomes 1 and 19 predicts earlier recurrence in anaplastic oligodendrogliomas with concurrent 1p/19q loss.

scientific article

Population-based estimates of survival among elderly patients with brain metastases

scientific article published on 17 October 2020

Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas

scientific article published on 19 October 2015

Prediction of Outcomes with a Computational Biology Model in Newly Diagnosed Glioblastoma Patients Treated with Radiation Therapy and Temozolomide

scientific article published on 14 May 2020

Prognostic factors in adult brainstem gliomas: a multicenter, retrospective analysis of 101 cases

scientific article

Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas

scientific article published on 04 March 2008

Proposed Response Assessment and Endpoints for Meningioma Clinical Trials: Report from the Response Assessment in Neuro-Oncology (RANO) Working Group

scientific article published on 01 January 2019

Pros and cons of current brain tumor imaging

scientific article

Prospective feasibility trial for genomics-informed treatment in recurrent and progressive glioblastoma.

scientific article published on 26 October 2017

Prospective, high-throughput molecular profiling of human gliomas ⬇️

scientific article published on July 22, 2012

Provider-reported challenges and barriers to referring patients to neuro-oncology clinical trials: a report from the Society for Neuro-Oncology member survey

scientific article published on 10 September 2019

Quantitative Imaging Biomarkers for Risk Stratification of Patients with Recurrent Glioblastoma Treated with Bevacizumab

scientific article published on 11 May 2017

Quo Vadis-Do Immunotherapies Have a Role in Glioblastoma?

scientific article

RARE-09. EFFICACY AND SAFETY OF DABRAFENIB + TRAMETINIB IN PATIENTS WITH RECURRENT/REFRACTORY BRAF V600E–MUTATED HIGH-GRADE GLIOMA (HGG)

RARE-11. EFFICACY AND SAFETY OF DABRAFENIB + TRAMETINIB IN PATIENTS WITH RECURRENT/REFRACTORY BRAF V600E–MUTATED LOW-GRADE GLIOMA (LGG)

RARE-24. OBJECTIVE RESPONSE AND CLINICAL BENEFIT IN RECURRENT EPENDYMOMA IN ADULTS: FINAL REPORT OF CERN 08-02: A PHASE II STUDY OF DOSE-DENSE TEMOZOLOMIDE AND LAPATINIB

RBTT-01. RANDOMIZED PHASE 2 OPEN LABEL STUDY OF NIVOLUMAB PLUS STANDARD DOSE BEVACIZUMAB VERSUS NIVOLUMAB PLUS LOW DOSE BEVACIZUMAB IN RECURRENT GLIOBLASTOMA

RBTT-03. A PHASE 1, MULTICENTER, RANDOMIZED, OPEN-LABEL, PERIOPERATIVE STUDY OF AG-120 (IVOSIDENIB) AND AG-881 IN PATIENTS WITH RECURRENT, NONENHANCING, IDH1-MUTANT, LOW-GRADE GLIOMA

RTOG 0913: a phase 1 study of daily everolimus (RAD001) in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma

scientific article

Radiation therapy for glioblastoma: Executive summary of an American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline

scientific article published on 31 March 2016

Radiographic Read Paradigms and the Roles of the Central Imaging Laboratory in Neuro-Oncology Clinical Trials

scientific article published on 01 November 2020

Radiographic prediction of meningioma grade by semantic and radiomic features

scientific article published on 16 November 2017

Radiotherapy and death from cerebrovascular disease in patients with primary brain tumors

scientific article published on 17 June 2015

Randomized phase II and biomarker study of pembrolizumab plus bevacizumab versus pembrolizumab alone for recurrent glioblastoma patients

scientific article published on 16 November 2020

Rapid Intraoperative Molecular Characterization of Glioma

scientific article published on 14 May 2015

Recent developments and future directions in adult lower-grade gliomas: Society for Neuro-Oncology (SNO) and European Association of Neuro-Oncology (EANO) consensus

scientific article published on 01 July 2019

Recurrent acute promyelocytic leukemia presenting as a sacral nerve root mass

scientific article published on 01 July 2008

Recurrent glioblastoma: volumetric assessment and stratification of patient survival with early posttreatment magnetic resonance imaging in patients treated with bevacizumab

scientific article published on 2 July 2013

Recurrent high-grade glioma

scientific article published on July 2010

Recurrent high-grade glioma treated with bevacizumab: prognostic value of MGMT methylation, EGFR status and pretreatment MRI in determining response and survival

scientific article published on 22 August 2013

Recursive partitioning analysis of prognostic variables in newly diagnosed anaplastic oligodendroglial tumors

scientific article

Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial

scientific article published on 01 August 2019

Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients

scientific article published on June 2015

Reply to B. Freidlin et al ⬇️

scientific article published on March 1, 2013

Reply to J.W. Locasale et al.

scientific article published on 5 December 2011

Report of the Jumpstarting Brain Tumor Drug Development Coalition and FDA clinical trials clinical outcome assessment endpoints workshop (October 15, 2014, Bethesda MD)

scientific article published on March 2016

Report of the Jumpstarting Brain Tumor Drug Development Coalition and FDA clinical trials neuroimaging endpoint workshop (January 30, 2014, Bethesda MD).

scientific article

Residual Convolutional Neural Network for Determination of IDH Status in Low- and High-grade Gliomas from MR Imaging

scientific article published on 22 November 2017

Response Assessment in Neuro-Oncology ⬇️

scientific article published on February 1, 2011

Response Assessment in Neuro-Oncology (RANO): more than imaging criteria for malignant glioma

scientific article published on 29 September 2015

Response Assessment in Neuro-Oncology Clinical Trials.

scientific article published on 22 June 2017

Response Assessment of Meningioma: 1D, 2D and Volumetric Criteria for Treatment Response and Tumor Progression

scientific article published on 01 February 2019

Response as a predictor of survival in patients with recurrent glioblastoma treated with bevacizumab ⬇️

scientific article published on November 17, 2010

Response assessment challenges in clinical trials of gliomas

scientific article published on January 2010

Response assessment criteria for brain metastases: proposal from the RANO group.

scientific article

Response assessment in paediatric high-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group

scientific article published on 01 June 2020

Response criteria for glioma

scientific article

Response to Letter to Editor

scientific article published on 21 August 2020

Response to Weltman and Fleury Malheiros, re Lassman et al.

scientific article

Retrospective analysis of the tolerability and activity of lacosamide in patients with brain tumors ⬇️

scientific article published on March 1, 2013

Retrospective study of carmustine or lomustine with bevacizumab in recurrent glioblastoma patients who have failed prior bevacizumab

scientific article

Retrospective study of pemetrexed as salvage therapy for central nervous system lymphoma ⬇️

scientific article published on 05 July 2013

Ridaforolimus for patients with progressive or recurrent malignant glioma: a perisurgical, sequential, ascending-dose trial ⬇️

scientific article published on October 30, 2011

Role of a second chemotherapy in recurrent malignant glioma patients who progress on bevacizumab

scientific article published on 30 March 2009

SM-03A RANDOMIZED, PLACEBO-CONTROLLED PILOT TRIAL OF ARMODAFINIL FOR FATIGUE IN PATIENTS WITH GLIOMAS UNDERGOING RADIOTHERAPY.

scientific article published in November 2014

Safety and efficacy of VB-111, an anti-cancer gene-therapy, in patients with recurrent glioblastoma: results of a phase I/II study

scientific article published on 17 December 2019

Safety of concurrent bevacizumab therapy and anticoagulation in glioma patients ⬇️

scientific article published on June 26, 2011

Salvage re-irradiation for recurrent high-grade glioma and comparison to bevacizumab alone

scientific article published on 3 October 2017

Seizure control as a new metric in assessing efficacy of tumor treatment in low-grade glioma trials.

scientific article

Seizures Among Patients with Brain Metastases: A Population- and Institutional-level Analysis

scientific article published on 05 January 2021

Signal transduction inhibitors and antiangiogenic therapies for malignant glioma ⬇️

scientific article published on February 23, 2011

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium

scientific article published on 07 January 2019

Spin-echo echo-planar perfusion prior to chemoradiation is a strong independent predictor of progression-free and overall survival in newly diagnosed glioblastoma

scientific article published on 4 May 2014

Successful Treatment of a Progressive BRAF V600E-Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy

scientific article published on 4 August 2014

Survival among patients with primary central nervous system lymphoma, 1973-2004.

scientific article published on 17 June 2010

Targeted drug therapy for meningiomas

scientific article published on January 2007

Targeted molecular therapy of malignant gliomas

scientific article

Targeted molecular therapy of malignant gliomas

scientific article published on 01 January 2006

Targeted therapies: Further delineating bevacizumab's response spectrum.

scientific article

Targeting DNA repair and the cell cycle in glioblastoma

scientific article

The 1p-encoded protein stathmin and resistance of malignant gliomas to nitrosoureas

scientific article published on April 2007

The FDA NIH Biomarkers, EndpointS, and other Tools (BEST) Resource in Neuro-Oncology

scientific article

The Impact of T2/FLAIR Evaluation per RANO Criteria on Response Assessment of Recurrent Glioblastoma Patients Treated with Bevacizumab

scientific article published on 21 October 2015

The Interface Between Neurology and Oncology

scientific article published on 13 June 2018

The Neurologic Assessment in Neuro-Oncology (NANO) scale: a tool to assess neurologic function for integration into the Response Assessment in Neuro-Oncology (RANO) criteria

scientific article published in May 2017

The RANO Leptomeningeal Metastasis Group proposal to assess response to treatment: lack of feasibility and clinical utility and a revised proposal

scientific article published on 01 May 2019

The lomustine crisis: awareness and impact of the 1500% price hike

scientific article published on 01 January 2019

The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients

scientific article published on 01 December 2019

The role of MGMT testing in clinical practice: a report of the association for molecular pathology

scientific article

The role of cytotoxic chemotherapy in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline

scientific article published on 17 April 2014

The role of targeted therapies in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline

scientific article published on 17 April 2014

The siren song of bevacizumab: swan song or clarion call?

scientific article published in January 2018

Therapeutic advances in the treatment of glioblastoma: rationale and potential role of targeted agents

scientific article

Therapeutic strategies for inhibiting invasion in glioblastoma

scientific article

Therapy for recurrent malignant glioma in adults

scientific article published in October 2004

Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma

scientific article published on 15 August 2019

Topotecan as salvage therapy for relapsed or refractory primary central nervous system lymphoma

scientific article

Toward a standard pathological and molecular characterization of recurrent glioma in adults: a Response Assessment in Neuro-Oncology effort

scientific article published on 17 December 2019

Toward precision medicine in glioblastoma: the promise and the challenges

scientific article published on May 2015

Treating anaplastic oligodendrogliomas and WHO grade 2 gliomas: PCV or temozolomide? The case for temozolomide

scientific article published on April 2015

Treatment Options in Newly Diagnosed Glioblastoma ⬇️

scientific article published on June 1, 2013

Treatment of recurrent high-grade gliomas

scientific article published on December 2009

Tumor associated seizures in glioblastomas are influenced by survival gene expression in a region-specific manner: a gene expression imaging study

scientific article

Unique challenges for glioblastoma immunotherapy - Discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology ⬇️

scientific article published on 24 December 2020

Update on bevacizumab and other angiogenesis inhibitors for brain cancer ⬇️

scientific article published on May 14, 2013

Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group

scientific article published on 15 March 2010

Updates in the management of brain metastases.

scientific article

Utility of claims data for delineation of intracranial treatment among patients with brain metastases

scientific article published on 21 July 2020

Vaccination with Irradiated Autologous Tumor Cells Mixed with Irradiated GM-K562 Cells Stimulates Antitumor Immunity and T Lymphocyte Activation in Patients with Recurrent Malignant Glioma

scientific article published on 12 February 2016

Validation of post-operative residual contrast enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma

scientific article published on 5 April 2018

Valproic acid as the AED of choice for patients with glioblastoma? ⬇️

scientific article published on August 31, 2011

Vandetanib plus sirolimus in adults with recurrent glioblastoma: results of a phase I and dose expansion cohort study

scientific article

Vessel architectural imaging identifies cancer patient responders to anti-angiogenic therapy

scientific article published on 18 August 2013

Volumetric Analysis of IDH-Mutant Lower-Grade Glioma: A Natural History Study of Tumor Growth Rates Before and After Treatment

scientific article published on 24 April 2020

Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma.

scientific article

Voxel-Wise Analysis of Fluoroethyltyrosine PET and MRI in the Assessment of Recurrent Glioblastoma During Antiangiogenic Therapy

scientific article published on 17 October 2018

Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) low-grade glioma research workshop.

scientific article published on 04 December 2013

Working plan for the use of patient-reported outcome measures in adults with brain tumours: a Response Assessment in Neuro-Oncology (RANO) initiative

scientific article published in March 2018

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