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List of works by Paul Helquist

2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease

scientific article published on 30 April 2019

Application of Q2MM to predictions in stereoselective synthesis

scholarly article by Anthony R Rosales et al published 24 July 2018 in Chemical Communications

Chemistry. Striking a balance to control stereochemistry

scientific article published on 01 September 2011

Conformational and SAR analysis of NAALADase and PSMA inhibitors

scientific article published on October 2003

Design and synthesis of a crosslinker for studying intracellular steroid trafficking pathways

scientific article published on 27 March 2015

Design, Synthesis, and Evaluation of a Luminescent Cholesterol Mimic

scientific article published on 28 December 2020

Development of a Q2MM Force Field for the Asymmetric Rhodium Catalyzed Hydrogenation of Enamides

scientific article published on August 2008

Development of carbamate-tethered coumarins as phototriggers for caged nicotinamide

scientific article

Diastereoselectivity in Lewis-Acid-Catalyzed Mukaiyama Aldol Reactions: A DFT Study ⬇️

scientific article published on August 31, 2012

Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts ⬇️

scientific article published on March 21, 2011

Identification of novel inhibitors for a low molecular weight protein tyrosine phosphatase via virtual screening

scientific article published on 21 April 2010

Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts

scientific article published on 27 May 2021

Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders.

scientific article published on January 2009

Inhibition studies with rationally designed inhibitors of the human low molecular weight protein tyrosine phosphatase

scientific article published in April 2004

Intramolecular hydroamination of aminoalkynes with silver-phenanthroline catalysts

scientific article published on 29 July 2008

Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics

scientific article published on October 2009

Mild and efficient desymmetrization of diynes via hydroamination: application to the synthesis of (+/-)-monomorine I.

scientific article published in February 2010

Ni-Catalyzed Alkenylation of Ketone Enolates under Mild Conditions: Catalyst Identification and Optimization

scientific article published on 29 May 2015

On the function of the 14 A long internal cavity of histone deacetylase-like protein: implications for the design of histone deacetylase inhibitors

scientific article

Palladium-catalyzed alkenylation of ketone enolates under mild conditions

scientific article published on 17 July 2014

Prediction of enantioselectivity in rhodium catalyzed hydrogenations

scientific article

QSAR studies of PC-3 cell line inhibition activity of TSA and SAHA-like hydroxamic acids

scientific article published on February 2004

Quantitative comparison of the efficacy of various compounds in lowering intracellular cholesterol levels in Niemann-Pick type C fibroblasts

scientific article

Single-Flask Multicomponent Palladium-Catalyzed α,γ-Coupling of Ketone Enolates: Facile Preparation of Complex Carbon Scaffolds

scientific article published on 14 August 2015

Single-Flask Multicomponent Synthesis of Highly Substituted α-Pyrones via a Sequential Enolate Arylation and Alkenylation Strategy

scientific article published on 21 October 2016

Stereoselectivity in (Acyloxy)borane-Catalyzed Mukaiyama Aldol Reactions

scientific article published on 13 June 2016

Stereoselectivity in Asymmetric Catalysis: The Case of Ruthenium-Catalyzed Ketone Hydrogenation

scientific article published in June 2014

Syntheses of conformationally constricted molecules as potential NAALADase/PSMA inhibitors

scientific article published on 01 May 2004

Synthesis and photochemical behavior of coumarin-caged cholesterol.

scientific article

Synthesis of 4-methyldienoates using a vinylogous Horner-Wadsworth-Emmons reagent. Application to the synthesis of trichostatic acid

scientific article published in March 2010

Synthesis of primary aryl amines through a copper-assisted aromatic substitution reaction with sodium azide

scientific article published on 01 July 2010

Synthesis, photophysical, photochemical, and computational studies of coumarin-labeled nicotinamide derivatives

scientific article published on 7 March 2012

Synthesis, structure, and metal complexation behavior of a new type of functionalized chiral phenanthroline derivative

scientific article published on 10 April 2008

Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics

scientific article published on July 2010

Toward selective histone deacetylase inhibitor design: homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases

scientific article published on 01 November 2005

Transition State Force Field for the Asymmetric Redox Relay Heck Reaction

scientific article published on 05 April 2020

Treatment of Niemann--pick type C disease by histone deacetylase inhibitors.

scientific article

Zinc binding in HDAC inhibitors: a DFT study

scientific article published on 19 June 2007

pHP-Tethered N-Acyl Carbamate: A Photocage for Nicotinamide.

scientific article published on 13 April 2018

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