List of works by Ralph Steinman

A comparison of murine epidermal Langerhans cells with spleen dendritic cells

scientific article published on 01 July 1985

A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q.

scientific article published in April 2006

A molecular strategy to identify molecules that are specific for dendritic cells and/or critical to their unique immunostimulatory function.

scientific article published on January 1995

A monoclonal antibody specific for mouse dendritic cells

scientific article

A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells

scientific article (publication date: August 2000)

A new synthetic TLR4 agonist, GLA, allows dendritic cells targeted with antigen to elicit Th1 T-cell immunity in vivo

scientific article

A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells

scientific journal article

A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels

scientific article

A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals

scientific article published in May 1999

A single vaccination with attenuated SIVmac 239 via the tonsillar route confers partial protection against challenge with SIVmac 251 at a distant mucosal site, the rectum

scientific article published on 01 January 2007

A small number of anti-CD3 molecules on dendritic cells stimulate DNA synthesis in mouse T lymphocytes

scientific article published on March 1989

A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo.

scientific article

APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection

scientific article

Accessory cell requirements for the mixed-leukocyte reaction and polyclonal mitogens, as studied with a new technique for enriching blood dendritic cells

scientific article published on 01 January 1988

Accessory cell-T lymphocyte interactions. Antigen-dependent and -independent clustering

scientific article published on February 1986

Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein

scientific article

Active immunization against cancer with dendritic cells: the near future

scientific article

Active replication of HIV-1 at the lymphoepithelial surface of the tonsil

scientific article published on July 1997

An IFN-gamma-IL-18 signaling loop accelerates memory CD8+ T cell proliferation

scientific article

An analysis of in vitro T cell responsiveness in lepromatous leprosy

scientific article

An antigen-independent contact mechanism as an early step in T cell-proliferative responses to dendritic cells

scientific article

Anti-CTLA-4 synergizes with dendritic cell-targeted vaccine to promote IL-3-dependent CD4+ effector T cell infiltration into murine pancreatic tumors

scientific article published on 04 April 2019

Antibody responses to T-dependent antigens: contributions of dendritic cells and helper T lymphocytes

scientific article published on 01 January 1985

Antibody to Langerin/CD207 localizes large numbers of CD8alpha+ dendritic cells to the marginal zone of mouse spleen

scholarly article

Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies.

scientific article

Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope

scientific article

Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain

scientific article

Antigen processing for amateurs and professionals

scientific article

Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses

scientific article

Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humans

scientific article published in July 2002

Antigen-specific T lymphocytes efficiently cluster with dendritic cells in the human primary mixed-leukocyte reaction

scientific article published on 01 January 1988

Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells

scientific article

Association of SIGNR1 with TLR4-MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria

scientific article

Atraumatic oral spray immunization with replication-deficient viral vector vaccines

scientific article published on 26 September 2007

Bioassays for the detection of a cytokine that enhances the development of cytolytic T lymphocytes

scientific article published on 01 October 1987

Bone marrow-derived chimerism in non-irradiated, cyclosporin-treated rats receiving microvascularized limb transplants: evidence for donor-derived dendritic cells in recipient lymphoid tissues

scientific article published on 01 November 1995

Both dendritic cells and memory T lymphocytes emigrate from organ cultures of human skin and form distinctive dendritic-T-cell conjugates

scientific article published on 01 January 1995

Broad T cell immunity to the LcrV virulence protein is induced by targeted delivery to DEC-205/CD205-positive mouse dendritic cells

scientific article

CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain

scientific article

CD141+ dendritic cells produce prominent amounts of IFN-α after dsRNA recognition and can be targeted via DEC-205 in humanized mice

scientific article published on 12 March 2013

CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

scientific article

CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells

scientific article

CD8+ T cells from most HIV-1-infected patients, even when challenged with mature dendritic cells, lack functional recall memory to HIV gag but not other viruses.

scientific article published in January 2005

Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell-proliferative responses via the type I calcitonin gene-related peptide receptor

scientific article published on 01 April 2000

Canarypox virus-induced maturation of dendritic cells is mediated by apoptotic cell death and tumor necrosis factor alpha secretion

scientific article published on December 2000

Cell type-dependent retention and transmission of HIV-1 by DC-SIGN.

scientific article published on February 2003

Classical Flt3L-dependent dendritic cells control immunity to protein vaccine

scientific article

Clustering of dendritic cells, helper T lymphocytes, and histocompatible B cells during primary antibody responses in vitro ⬇️

scientific article published on September 1, 1984

Clustering with dendritic cells precedes and is essential for T-cell proliferation in a mitogenesis model

scientific article published on 01 April 1988

Coexpression of NF-kappa B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia

scientific article

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

scientific article

Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1

scientific article published on 01 August 1994

Contribution of dendritic cells to stimulation of the murine syngeneic mixed leukocyte reaction

scientific article

Correction: Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity.

scientific article published on 19 September 2013

CpG oligonucleotides induce strong humoral but only weak CD4+ T cell responses to protein antigens in rhesus macaques in vivo

article

Cross-presentation of glycolipid from tumor cells loaded with alpha-galactosylceramide leads to potent and long-lived T cell mediated immunity via dendritic cells

scientific article

Cutaneous Dendritic Cells Promote Replication of Immunodeficiency Viruses ⬇️

scientific article published on 01 January 1997

Cutting edge: langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo

scientific article published on 01 March 2008

DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells

scientific article

DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes

scientific article

DEC-205, a 205-kDa protein abundant on mouse dendritic cells and thymic epithelium that is detected by the monoclonal antibody NLDC-145: purification, characterization, and N-terminal amino acid sequence

scientific article published on 01 October 1995

DEC-205/CD205+ dendritic cells are abundant in the white pulp of the human spleen, including the border region between the red and white pulp

scientific article published on 16 October 2007

Decisions about dendritic cells: past, present, and future

scientific article

Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2.

scientific article

Dendritic Cell Development and Maturation ⬇️

scientific article published on January 1, 1997

Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance ⬇️

scientific article published on April 1, 2003

Dendritic Cells Induce a Subpopulation of IL-12Rβ2-Expressing Treg that Specifically Consumes IL-12 to Control Th1 Responses

scientific article published on 8 January 2016

Dendritic Cells as Immunogens for Human CTL Responses ⬇️

scientific article published on 01 January 1997

Dendritic Cells: Features and Functions ⬇️

scientific article published on January 1, 1980

Dendritic and B-cell function during antibody responses in normal and immunodeficient (xid) mouse spleen cultures

scientific article published on 01 April 1987

Dendritic cell maturation by innate lymphocytes: coordinated stimulation of innate and adaptive immunity

scientific article

Dendritic cell numbers in the blood of HIV-1 infected patients before and after changes in antiretroviral therapy

scientific article published on 01 November 2004

Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo ⬇️

scientific article published on August 1, 1993

Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells

scientific article

Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin

scientific article published on 01 December 2006

Dendritic cell-T cell conjugates that migrate from normal human skin are an explosive site of infection for HIV-1.

scientific article published on January 1995

Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice

scientific article

Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin/CD209 is abundant on macrophages in the normal human lymph node and is not required for dendritic cell stimulation of the mixed leukocyte reaction

scientific article

Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity

scientific article published on 4 January 2012

Dendritic cells and macrophages can mature independently from a human bone marrow-derived, post-colony-forming unit intermediate

scientific article published on 01 June 1996

Dendritic cells and the control of immunity

scientific article (publication date: 19 March 1998)

Dendritic cells and vaccines

scientific article published on January 2008

Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes

scientific article

Dendritic cells are critical accessory cells for thymus-dependent antibody responses in mouse and in man ⬇️

scientific article published on October 1, 1983

Dendritic cells are specialized accessory cells along with TGF- for the differentiation of Foxp3+ CD4+ regulatory T cells from peripheral Foxp3 precursors

scientific article

Dendritic cells are the principal cells in mouse spleen bearing immunogenic fragments of foreign proteins ⬇️

scientific article published on July 1, 1990

Dendritic cells are the principal stimulators of the primary mixed leukocyte reaction in mice

scientific article

Dendritic cells as adjuvants for immune-mediated resistance to tumors

scientific article published on October 1997

Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells

scientific article published on 14 March 2009

Dendritic cells at a DNA vaccination site express the encoded influenza nucleoprotein and prime MHC class I-restricted cytolytic lymphocytes upon adoptive transfer

scientific article published on 01 June 2000

Dendritic cells charged with apoptotic tumor cells induce long-lived protective CD4+ and CD8+ T cell immunity against B16 melanoma

scientific article published on December 2003

Dendritic cells cross-present latency gene products from Epstein-Barr virus-transformed B cells and expand tumor-reactive CD8(+) killer T cells

scientific article

Dendritic cells crossprime allo-specific self-restricted CD4(+) T cells after coculture with dead allogeneic cells

scientific article published on July 2002

Dendritic cells efficiently immunoselect mycobacterial-reactive T cells in human blood, including clonable antigen-reactive precursors

scientific article

Dendritic cells expand Epstein Barr virus specific CD8+ T cell responses more efficiently than EBV transformed B cells

scientific article published on September 2005

Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity.

scientific article published on August 2006

Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells

scientific article published on July 17, 1992

Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium

scientific article

Dendritic cells generated from blood monocytes of HIV-1 patients are not infected and act as competent antigen presenting cells eliciting potent T-cell responses

scientific article published in March 1999

Dendritic cells in the T-cell areas of lymphoid organs

scientific article (publication date: April 1997)

Dendritic cells in transplantation--friend or foe?

scientific article

Dendritic cells in vivo: a key target for a new vaccine science

scientific article published on 01 September 2008

Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism ⬇️

scientific article published on December 1, 1983

Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice

scientific article published on 14 November 2011

Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

scientific article published on 17 September 2001

Dendritic cells initiate a two-stage mechanism for T lymphocyte proliferation ⬇️

scientific article published on April 1, 1983

Dendritic cells initiate immune control of epstein-barr virus transformation of B lymphocytes in vitro

scientific article

Dendritic cells of the mouse: identification and characterization

scientific article published on 01 July 1980

Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ

scientific article

Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant

scientific article published on 29 June 2009

Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells

scholarly article

Dendritic cells, infected with vesicular stomatitis virus-pseudotyped HIV-1, present viral antigens to CD4+ and CD8+ T cells from HIV-1-infected individuals

scientific article published in December 2000

Dendritic cells: antigen presentation, accessory function and clinical relevance.

scientific article

Dendritic cells: from the fabric of immunology

scientific article published on 01 October 2004

Dendritic cells: translating innate to adaptive immunity.

scientific article published on January 2006

Dendritic cells: understanding immunogenicity

scientific article published on November 2007

Detection and activation of human Valpha24+ natural killer T cells using alpha-galactosyl ceramide-pulsed dendritic cells

scientific article published on January 2003

Development of cytolytic T lymphocytes in thymus culture requires a cytokine sharing homology with IL-6 alpha

scientific article published on 01 January 1989

Developmental regulation of MHC class II transport in mouse dendritic cells.

scientific article published on August 1997

Differential antigen processing by dendritic cell subsets in vivo

scientific article (publication date: 5 January 2007)

Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking

scientific article published on 01 October 1998

Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo

scientific article published on 01 December 1999

Direct activation of CD8+ cytotoxic T lymphocytes by dendritic cells

scientific article

Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells

scientific article

Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation

scientific article

Distinct features of dendritic cells and anti-Ig activated B cells as stimulators of the primary mixed leukocyte reaction

scientific article

Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice

scientific article

During HIV-1 infection most blood dendritic cells are not productively infected and can induce allogeneic CD4+ T cells clonal expansion

scientific article published on May 1, 1992

EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function

scientific article published in January 2001

ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis

scientific article published on 27 April 2015

Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus

scholarly article

Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction

scholarly article

Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors

scientific article published on December 1996

Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells

scientific article

Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

scientific article

Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells

scientific article published on 01 October 2002

Enhanced T-cell responses to glioma cells coated with the anti-EGF receptor antibody and targeted to activating FcgammaRs on human dendritic cells

scientific article

Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis.

scientific article

Epitope mapping on the dendritic cell-specific ICAM-3-grabbing non-integrin (DC-SIGN) pathogen-attachment factor

scientific article published on 30 October 2009

Evidence that cyclosporine inhibits cell-mediated immunity primarily at the level of the T lymphocyte rather than the accessory cell

scientific article published on 01 August 1988

Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients

scientific article published on 8 June 2006

Exploiting dendritic cells to improve vaccine efficacy

scientific article

Expression of B7 costimulator molecules on mouse dendritic cells

scientific article published on 01 January 1995

Expression of a functional eotaxin (CC chemokine ligand 11) receptor CCR3 by human dendritic cells.

scientific article published on September 2002

Features of the dendritic cell lineage

scientific article published on 01 March 2010

Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN

scientific journal article

Flt3 signaling-dependent dendritic cells protect against atherosclerosis

scientific article published on 10 November 2011

Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain

scientific article

Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells

scientific article

Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins

scientific article published on 19 April 2004

Generation and application of new rat monoclonal antibodies against synthetic FLAG and OLLAS tags for improved immunodetection.

scientific article published on 26 November 2007

Generation of anti-human DEC205/CD205 monoclonal antibodies that recognize epitopes conserved in different mammals.

scientific article

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor ⬇️

scientific article (publication date: December 1992)

Generation or large numbers of immature and mature dendritic cells from rat bone marrow cultures

scientific article published on 01 March 1998

Glycolipid alpha-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice

scholarly article

Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells

scientific article

Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow

scientific article

Growth factor production and requirements during the proliferative response of human T lymphocytes to anti-CD3 monoclonal antibody

scientific article published on 01 June 1989

HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC.

scientific article published on January 2010

HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood

scientific article published on 01 January 2006

HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation

scholarly article

Harnessing the immune system against human glioma

scientific article

High Levels of a Major Histocompatibility Complex II–Self Peptide Complex on Dendritic Cells from the T Cell Areas of Lymph Nodes ⬇️

scientific article published on August 29, 1997

High and low affinity carbohydrate ligands revealed for murine SIGN-R1 by carbohydrate array and cell binding approaches, and differing specificities for SIGN-R3 and langerin

scientific article

Human CD4(+) T lymphocytes consistently respond to the latent Epstein-Barr virus nuclear antigen EBNA1.

scientific article

Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature

scientific article published on 01 July 1994

Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells

scientific article

Human dendritic cells. Enrichment and characterization from peripheral blood

scientific article published in April 1982

IL-6 enhances the generation of cytolytic T lymphocytes in the allogeneic mixed leucocyte reaction

scientific article published on July 1, 1992

IL-6/IFN-beta 2 in synovial effusions of patients with rheumatoid arthritis and other arthritides. Identification of several isoforms and studies of cellular sources.

scientific article

Identification and expression of mouse Langerin (CD207) in dendritic cells

scientific journal article

Identification of a 24-kDa cytokine that is required for development of cytolytic T lymphocytes

scientific article

Identification of a novel cell type in peripheral lymphoid organs of mice. 3. Functional properties in vivo ⬇️

scientific article published on June 1, 1974

Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution ⬇️

scientific article published on May 1, 1973

Identification of a novel cell type in peripheral lymphoid organs of mice. II. Functional properties in vitro ⬇️

scientific article published on February 1, 1974

Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro

scientific article

Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves

scientific article published on 16 February 2009

Identification of macrophages and dendritic cells in the osteopetrotic (op/op) mouse.

scientific article published in April 1993

Identification of proliferating dendritic cell precursors in mouse blood

scientific article

Immature dendritic cells selectively replicate macrophagetropic (M-tropic) human immunodeficiency virus type 1, while mature cells efficiently transmit both M- and T-tropic virus to T cells.

scientific article published on April 1998

Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine

scientific article published on 01 September 2001

Immune tolerance after delivery of dying cells to dendritic cells in situ

scientific article

Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates.

scientific article

Immunogenicity and efficacy of immunodeficiency virus-like particles pseudotyped with the G protein of vesicular stomatitis virus

scientific article published on 17 April 2006

Immunologic properties of purified epidermal Langerhans cells. Distinct requirements for stimulation of unprimed and sensitized T lymphocytes

scientific article published on August 1986

Immunotherapy: bewitched, bothered, and bewildered no more

scientific article

Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti–human DEC205 monoclonal antibody ⬇️

scientific article published on July 28, 2010

Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood.

scientific article

In vivo targeting of HIV gag to dendritic cells in combination with poly ICLC is safe and immunogenic in healthy volunteers

scientific article published on 13 September 2012

In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination

scientific article

In vivo targeting of protein antigens to dendritic cells using anti-DEC-205 single chain antibody improves HIV Gag specific CD4(+) T cell responses protecting from airway challenge with recombinant vaccinia-gag virus

scientific article published on 13 March 2017

Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

scholarly article

Increased macrophage infection upon subcutaneous inoculation of rhesus macaques with simian immunodeficiency virus-loaded dendritic cells or T cells but not with cell-free virus

scientific article

Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity

scientific article

Induction of Epstein-Barr virus-specific cytotoxic T-lymphocyte responses using dendritic cells pulsed with EBNA-3A peptides or UV-inactivated, recombinant EBNA-3A vaccinia virus

scientific article published in August 1999

Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells

scientific article published on 17 February 2013

Induction of interleukin 1 alpha mRNA during the antigen-dependent interaction of sensitized T lymphoblasts with macrophages

scientific article

Induction of neutralising antibodies restricts the use of human granulocyte/macrophage colony stimulating factor for vaccine studies in rhesus macaques.

scientific article published in September 2004

Induction of pulmonary mucosal immune responses with a protein vaccine targeted to the DEC-205/CD205 receptor

scientific article

Infection and apoptotic cell death of CD4+ T cells during an immune response to HIV-1-pulsed dendritic cells

scientific article published on 01 January 1994

Influence of delayed immune reactions on human epidermal keratinocytes

scientific article published on May 1986

Influenza virus-induced dendritic cell maturation is associated with the induction of strong T cell immunity to a coadministered, normally nonimmunogenic protein

scientific article

Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells

scientific article

Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells

scientific article

Innate Valpha14(+) natural killer T cells mature dendritic cells, leading to strong adaptive immunity

scientific article published on December 2007

Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine

scientific article

Interleukin 1 enhances T-dependent immune responses by amplifying the function of dendritic cells

scientific article

Interleukin 1 production during accessory cell-dependent mitogenesis of T lymphocytes

scientific article

Interleukin-1 production by mononuclear cells from rheumatoid synovial effusions

scientific article published on 01 July 1988

Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-gamma production by T helper 1 cells.

scientific article published in March 1996

Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis

scientific article

Intracellular iodination of lysosome membrane for studies of membrane composition and recycling

scientific article published on 01 January 1983

Invariant natural killer T cells are preserved in patients with glioma and exhibit antitumor lytic activity following dendritic cell-mediated expansion

scientific article published in May 2004

Isolation of dendritic cells

scientific article

Isolation of dendritic cells

scientific article published on 01 August 2009

James Gerald Hirsch

scientific article published on 01 January 2004

Lasker Basic Medical Research Award. Dendritic cells: versatile controllers of the immune system

scientific article published in October 2007

Linking innate to adaptive immunity through dendritic cells.

scientific article published on January 2006

Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo ⬇️

scientific article published on October 20, 2003

Liver macrophages in murine listeriosis. Cell-mediated immunity is correlated with an influx of macrophages capable of generating reactive oxygen intermediates

scientific article

Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy

scientific article published on 01 July 1986

Localization and Intracellular Transport of MHC Class II Molecules in Bone Marrow-Derived Dendritic Cells ⬇️

scientific article published on 01 January 1997

Low levels of HIV-1 infection in cutaneous dendritic cells promote extensive viral replication upon binding to memory CD4+ T cells

scientific article

Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract

scientific article published on 19 August 2013

Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A

scientific article

Lymphokine enhances the expression and synthesis of Ia antigens on cultured mouse peritoneal macrophages

scientific article

Macrophages control the retention and trafficking of B lymphocytes in the splenic marginal zone

scientific article

Macrophages, but not dendritic cells, accumulate colloidal carbon following administration in situ ⬇️

scientific article published on 01 August 1993

Mass spectrometry analysis and quantitation of peptides presented on the MHC II molecules of mouse spleen dendritic cells

scientific article published on 14 October 2011

Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes

scientific article published on March 2000

Mature dendritic cells infected with canarypox virus elicit strong anti-human immunodeficiency virus CD8+ and CD4+ T-cell responses from chronically infected individuals

scientific article published in March 2001

Mature dendritic cells respond to SDF-1, but not to several beta-chemokines

scientific article published on 01 March 1998

Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas.

scientific article

Migration and maturation of Langerhans cells in skin transplants and explants

scientific article

Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes

scientific article

Mononuclear phagocytes as targets for cytolytic T lymphocytes

scientific article published on 01 June 1987

Mouse spleen lymphoblasts generated in vitro. Their replication and differentiation in vitro ⬇️

scientific article published on February 1, 1978

Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates

scientific article

Murine Langerin dermal dendritic cells prime CD8 T cells while Langerhans cells induce cross-tolerance

Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance

scientific article

Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro

scientific article

Network of dendritic cells within the muscular layer of the mouse intestine

scientific article

Neutralizing monoclonal antibodies block human immunodeficiency virus type 1 infection of dendritic cells and transmission to T cells.

scientific article published on December 1998

New monoclonal anti-mouse DC-SIGN antibodies reactive with acetone-fixed cells

scientific article

Newcastle disease virus expressing a dendritic cell-targeted HIV gag protein induces a potent gag-specific immune response in mice

scientific article

Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages

scientific article published on September 2007

PE-Cy5.5 conjugates bind to the cells expressing mouse DEC205/CD205.

scientific article published on 25 July 2012

Paucity of functional T-cell memory to melanoma antigens in healthy donors and melanoma patients

scientific article published on 01 December 2000

Pillars Article: Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking. Science. 1998. 282: 480-483

Pillars Article: Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J. Exp. Med.1973. 137: 1142-1162.

scientific article

Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates

scientific article

Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells

scientific article published on 7 October 2002

Presentation of SIVgag to monkey T cells using dendritic cells transfected with a recombinant adenovirus

scientific article published on 01 November 2000

Presentation of epstein-barr virus latency antigens to CD8(+), interferon-gamma-secreting, T lymphocytes

scientific article published in December 1999

Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells

scientific article

Presentation of mycobacterial antigens by human dendritic cells: lack of transfer from infected macrophages ⬇️

scientific article published on December 1, 1993

Presentation of proteins encapsulated in sterically stabilized liposomes by dendritic cells initiates CD8(+) T-cell responses in vivo

scientific article published on 01 November 2000

Production of monoclonal antibodies that recognize the extracellular domain of mouse langerin/CD207.

scientific article published on 24 May 2007

Proliferating dendritic cell progenitors in human blood

scientific article

Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs.

scientific article

Properties of isolated red pulp macrophages from mouse spleen

scientific article

Properties of memory T lymphocytes isolated from the mixed leukocyte reaction

scientific article

Quantitation of surface antigens on cultured murine epidermal Langerhans cells: rapid and selective increase in the level of surface MHC products

scientific article published on 01 March 1988

Ralph Steinman--pioneering new perspectives on the immune system and infectious diseases. Interviewed by Marilynn Larkin

scientific article published in June 2003

Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells.

scientific article

Recombinant adenovirus is an efficient and non-perturbing genetic vector for human dendritic cells

scientific article published in March 1999

Relative efficacy of human monocytes and dendritic cells as accessory cells for T cell replication

scientific article

Replication of HIV-1 in dendritic cell-derived syncytia at the mucosal surface of the adenoid

scientific article published on 01 April 1996

Research on human subjects in the JEM.

scientific article published on May 2005

Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release ⬇️

scientific article published on December 1, 1984

SIGN-R1, a novel C-type lectin expressed by marginal zone macrophages in spleen, mediates uptake of the polysaccharide dextran.

scientific article published in February 2003

Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells

scientific article

Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type I interferon response program

scientific article

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

scientific article published in October 2007

Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.

scholarly article

Single injection of CD34+ progenitor-derived dendritic cell vaccine can lead to induction of T-cell immunity in patients with stage IV melanoma

scientific article published on 01 September 2003

Small amounts of superantigen, when presented on dendritic cells, are sufficient to initiate T cell responses

scientific article

SnapShot: Dendritic Cells

scientific article published on 01 August 2011

Some active areas of DC research and their medical potential ⬇️

scientific article published on August 1, 2010

Some interfaces of dendritic cell biology

scientific article

Some scientific and organizational challenges in cancer immunology.

scientific article

Specialized role of migratory dendritic cells in peripheral tolerance induction

scientific article published on 9 January 2013

Specific antimononuclear phagocyte monoclonal antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages

scientific article published on July 1983

Spleen deposition of Cryptococcus neoformans capsular glucuronoxylomannan in rodents occurs in red pulp macrophages and not marginal zone macrophages expressing the C-type lectin SIGN-R1

scientific article

Stimulation of human anti-viral CD8+ cytolytic T lymphocytes by dendritic cells

scientific article published on January 1995

Stimulation of lymphokine release from T lymphoblasts. Requirement for mRNA synthesis and inhibition by cyclosporin A ⬇️

scientific article published on December 1, 1984

Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein.

scientific article

Studies of the cell surface of mouse dendritic cells and other leukocytes

scientific article

Susceptibility of dendritic cells to HIV-1 infection in vitro.

scientific article published on September 1994

Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients

scientific article

Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients

scientific article published in October 2007

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

scientific article published on 7 November 2011

Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques

scientific article

T cell studies in a peptide-induced model of systemic lupus erythematosus

scientific article published on 01 February 2001

TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor

scientific article

TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells

article

TRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activation

scientific article

TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo

scientific article

Taking dendritic cells into medicine

scientific article (publication date: 27 September 2007)

Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity

scientific article (publication date: 2013)

Targeting of LcrV virulence protein from Yersinia pestis to dendritic cells protects mice against pneumonic plague.

scientific article published on October 2010

Targeting of antigens to skin dendritic cells: possibilities to enhance vaccine efficacy

scientific article

Targeting of envelope domain III protein of DENV type 2 to DEC-205 receptor elicits neutralizing antibodies in mice

scientific article published on 15 March 2013

Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice

scientific article

Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses.

scientific article published on 2 June 2008

The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide of Streptococcus pneumoniae in the marginal zone of mouse spleen.

scholarly article

The CD8+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo

scientific article

The Cutaneous Infiltrates of Leprosy

article

The HIV-1 life cycle is blocked at two different points in mature dendritic cells

scientific article published on 01 January 1997

The JEM and the JCB: a synergistic partnership

scientific article published on August 2004

The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor

scientific article

The Thy-1-bearing cell of murine epidermis. A distinctive leukocyte perhaps related to natural killer cells

scientific article

The binding of antigen presenting cells to T lymphocytes

scientific article published on January 1988

The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus

scientific article published on 01 January 1989

The decreased replicative capacity of simian immunodeficiency virus SIVmac239Delta(nef) is manifest in cultures of immature dendritic cellsand T cells

scientific article

The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments

scientific article

The distinct surface of human blood dendritic cells, as observed after an improved isolation method

scientific article

The effect of immunosuppressive agents on the induction of nuclear factors that bind to sites on the interleukin 2 promoter ⬇️

scientific article published on December 1, 1990

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

scientific article

The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli

scientific article

The function of Ia+ dendritic cells and Ia- dendritic cell precursors in thymocyte mitogenesis to lectin and lectin plus interleukin 1.

scientific article

The human cancer antigen mesothelin is more efficiently presented to the mouse immune system when targeted to the DEC-205/CD205 receptor on dendritic cells

scientific article

The immunodeficiency virus coreceptor, Bonzo/STRL33/TYMSTR, is expressed by macaque and human skin- and blood-derived dendritic cells

scientific article

The immunological and infectious sequelae of the acquired immune deficiency syndrome

scientific article

The induction of tolerance by dendritic cells that have captured apoptotic cells

scientific article

The innate functions of dendritic cells in peripheral lymphoid tissues.

scientific article

The interaction of HIV with dendritic cells: outcomes and pathways

scientific article published on 22 October 2007

The interaction of immunodeficiency viruses with dendritic cells

scientific article

The interactions of dendritic cells with antigen-specific, regulatory T cells that suppress autoimmunity

scientific article

The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation

scientific article

The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine

scholarly article

The phenotype of dendritic cells and macrophages

scientific article published on 01 November 1983

The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

scientific article

The simian immunodeficiency virus deltaNef vaccine, after application to the tonsils of Rhesus macaques, replicates primarily within CD4(+) T cells and elicits a local perforin-positive CD8(+) T-cell response

scientific article published on January 2002

The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro

scientific article

The unenlarged lymph nodes of HIV-1-infected, asymptomatic patients with high CD4 T cell counts are sites for virus replication and CD4 T cell proliferation. The impact of highly active antiretroviral therapy

scientific article

The use of dendritic cells in cancer immunotherapy

scientific article

Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. I. Expression on dendritic cells and other subsets of mouse leukocytes

scientific article published on 01 June 1995

Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. II. Expression in situ in lymphoid and nonlymphoid tissues

scientific article published on 01 June 1995

Tolerizing mice to human leukocytes: a step toward the production of monoclonal antibodies specific for human dendritic cells.

scientific article published in January 1993

Tolerogenic dendritic cells

scientific article published in 2003

Transport of peptide-MHC class II complexes in developing dendritic cells

scientific article

Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein

scientific journal article

Two populations of splenic dendritic cells detected with M342, a new monoclonal to an intracellular antigen of interdigitating dendritic cells and some B lymphocytes ⬇️

scientific article published on 01 July 1992

Unusual phenotype of B cells in the thymus of normal mice

scientific article

Use of the fluorescence activated cell sorter to enrich dendritic cells from mouse spleen

scientific article published on 01 October 1990

Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma

scientific article

Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion.

scientific article published in December 1999

Will the making of plasmacytoid dendritic cells in vitro help unravel their mysteries?

scientific article published on December 2000

siRNA knockdown of PD-L1 and PD-L2 in monocyte-derived dendritic cells only modestly improves proliferative responses to Gag by CD8(+) T cells from HIV-1-infected individuals

scientific article

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