List of works - Jean-François Dubremetz

A MORN-repeat protein is a dynamic component of the Toxoplasma gondii cell division apparatus

scientific article

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

scientific article

An Alveolata secretory machinery adapted to parasite host cell invasion.

scientific article published on 25 January 2021

Apicomplexan cytoskeleton and motors: key regulators in morphogenesis, cell division, transport and motility.

scientific article

Autophagy protein Atg3 is essential for maintaining mitochondrial integrity and for normal intracellular development of Toxoplasma gondii tachyzoites

scientific article (publication date: December 2011)

Basal body structure and composition in the apicomplexans Toxoplasma and Plasmodium

scientific article

Biogenesis of nanotubular network in Toxoplasma parasitophorous vacuole induced by parasite proteins

scientific article

Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella

scientific article

Characterization, biosynthesis and fate of ROP7, a ROP2 related rhoptry protein of Toxoplasma gondii

scientific article

Comparative analysis of anti-toxoplasmic activity of antipsychotic drugs and valproate

scientific article

Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs

scientific article

Evidence for de novo sphingolipid biosynthesis in Toxoplasma gondii

scientific article

Export of a Toxoplasma gondii rhoptry neck protein complex at the host cell membrane to form the moving junction during invasion ⬇️

scientific article

Food vacuole proteome of the malarial parasite Plasmodium falciparum ⬇️

scientific article (publication date: September 2008)

Functional domains of the Toxoplasma GRA2 protein in the formation of the membranous nanotubular network of the parasitophorous vacuole

scientific article published on 01 November 2007

GRA12, a Toxoplasma dense granule protein associated with the intravacuolar membranous nanotubular network

scientific article published on 20 September 2008

GRA9, a new Toxoplasma gondii dense granule protein associated with the intravacuolar network of tubular membranes

scientific article published on October 2004

Gliding motility powers invasion and egress in Apicomplexa.

scientific article

Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite.

scientific article published on 30 August 2014

Identification of a new rhoptry neck complex RON9/RON10 in the Apicomplexa parasite Toxoplasma gondii

scientific article

Innate refractoriness of the Lewis rat to toxoplasmosis is a dominant trait that is intrinsic to bone marrow-derived cells

scientific article

Intravacuolar Membranes Regulate CD8 T Cell Recognition of Membrane-Bound Toxoplasma gondii Protective Antigen

scientific article

Inverted topology of the Toxoplasma gondii ROP5 rhoptry protein provides new insights into the association of the ROP2 protein family with the parasitophorous vacuole membrane

scientific article published on 31 July 2006

Kiss and spit: the dual roles of Toxoplasma rhoptries

scientific article published on January 2008

Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii

scientific article

Lipidomic analysis of Toxoplasma gondii tachyzoites rhoptries: further insights into the role of cholesterol

scientific article published in October 2008

Mic1-3KO tachyzoite a live attenuated vaccine candidate against toxoplasmosis derived from a type I strain shows features of type II strain

scientific article

Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1.

scientific article

Molecular signals in the trafficking of Toxoplasma gondii protein MIC3 to the micronemes

scientific article

Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation.

scientific article published on 24 February 2014

Novel Plasmodium falciparum Maurer's clefts protein families implicated in the release of infectious merozoites

scientific article (publication date: April 2013)

Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii.

scientific article

Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis

scientific article (publication date: February 2011)

Phosphatidylinositol 3-phosphate, an essential lipid in Plasmodium, localizes to the food vacuole membrane and the apicoplast.

scientific article

Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii

scientific article (publication date: July 2006)

Potent antihematozoan activity of novel bisthiazolium drug T16: evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.

scientific article

ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii

scientific article

ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity

scientific article

Regulation of ATG8 membrane association by ATG4 in the parasitic protist Toxoplasma gondii

scientific article published on 6 June 2013

Rhoptries are major players in Toxoplasma gondii invasion and host cell interaction

scientific article published on 8 March 2007

Subcellular localization and dynamics of a digalactolipid-like epitope in Toxoplasma gondii.

scientific article published on 8 January 2008

Synergistic role of micronemal proteins in Toxoplasma gondii virulence

scientific article

The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites

scientific article (publication date: 10 February 2011)

The ROP2 family of Toxoplasma gondii rhoptry proteins: proteomic and genomic characterization and molecular modeling

scientific article published in November 2006

The Toxoplasma gondii protein MIC3 requires pro-peptide cleavage and dimerization to function as adhesin

scientific article published on June 2002

The moving junction of apicomplexan parasites: a key structure for invasion

scientific article published on 28 April 2011

The rhoptry neck protein RON4 re-localizes at the moving junction during Toxoplasma gondii invasion

scientific article published on December 2005

The role played by electron microscopy in advancing our understanding of Toxoplasma gondii and other apicomplexans

scientific article

Towards a molecular architecture of the centrosome in Toxoplasma gondii

scientific article published on 27 December 2016

Toxoplasma gondii grown in human cells uses GalNAc-containing glycosylphosphatidylinositol precursors to anchor surface antigens while the immunogenic Glc-GalNAc-containing precursors remain free at the parasite cell surface

scientific article published on 27 May 2006

Toxoplasma gondii secretory proteins bind to sulfated heparin structures

scientific article

Toxoplasma gondii uses unusual sorting mechanisms to deliver transmembrane proteins into the host-cell vacuole

scientific article

Transient infection of the zebrafish notochord with E. coli induces chronic inflammation

scientific article

Virulence factors of Toxoplasma gondii

scientific article published on 21 September 2012

Virulent and avirulent strains of Toxoplasma gondii which differ in their glycosylphosphatidylinositol content induce similar biological functions in macrophages.

scientific article published on 28 January 2014

Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cells

scientific article

List of works by Jean-François Dubremetz

A MORN-repeat protein is a dynamic component of the Toxoplasma gondii cell division apparatus

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

An Alveolata secretory machinery adapted to parasite host cell invasion.

Apicomplexan cytoskeleton and motors: key regulators in morphogenesis, cell division, transport and motility.

Autophagy protein Atg3 is essential for maintaining mitochondrial integrity and for normal intracellular development of Toxoplasma gondii tachyzoites

Basal body structure and composition in the apicomplexans Toxoplasma and Plasmodium

Biogenesis of nanotubular network in Toxoplasma parasitophorous vacuole induced by parasite proteins

Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella

Characterization, biosynthesis and fate of ROP7, a ROP2 related rhoptry protein of Toxoplasma gondii

Comparative analysis of anti-toxoplasmic activity of antipsychotic drugs and valproate

Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs

Evidence for de novo sphingolipid biosynthesis in Toxoplasma gondii

Export of a Toxoplasma gondii rhoptry neck protein complex at the host cell membrane to form the moving junction during invasion ⬇️

Food vacuole proteome of the malarial parasite Plasmodium falciparum ⬇️

Functional domains of the Toxoplasma GRA2 protein in the formation of the membranous nanotubular network of the parasitophorous vacuole

GRA12, a Toxoplasma dense granule protein associated with the intravacuolar membranous nanotubular network

GRA9, a new Toxoplasma gondii dense granule protein associated with the intravacuolar network of tubular membranes

Gliding motility powers invasion and egress in Apicomplexa.

Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite.

Identification of a new rhoptry neck complex RON9/RON10 in the Apicomplexa parasite Toxoplasma gondii

Innate refractoriness of the Lewis rat to toxoplasmosis is a dominant trait that is intrinsic to bone marrow-derived cells

Intravacuolar Membranes Regulate CD8 T Cell Recognition of Membrane-Bound Toxoplasma gondii Protective Antigen

Inverted topology of the Toxoplasma gondii ROP5 rhoptry protein provides new insights into the association of the ROP2 protein family with the parasitophorous vacuole membrane

Kiss and spit: the dual roles of Toxoplasma rhoptries

Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii

Lipidomic analysis of Toxoplasma gondii tachyzoites rhoptries: further insights into the role of cholesterol

Mic1-3KO tachyzoite a live attenuated vaccine candidate against toxoplasmosis derived from a type I strain shows features of type II strain

Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1.

Molecular signals in the trafficking of Toxoplasma gondii protein MIC3 to the micronemes

Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation.

Novel Plasmodium falciparum Maurer's clefts protein families implicated in the release of infectious merozoites

Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii.

Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis

Phosphatidylinositol 3-phosphate, an essential lipid in Plasmodium, localizes to the food vacuole membrane and the apicoplast.

Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii

Potent antihematozoan activity of novel bisthiazolium drug T16: evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.

ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii

ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity

Regulation of ATG8 membrane association by ATG4 in the parasitic protist Toxoplasma gondii

Rhoptries are major players in Toxoplasma gondii invasion and host cell interaction

Subcellular localization and dynamics of a digalactolipid-like epitope in Toxoplasma gondii.

Synergistic role of micronemal proteins in Toxoplasma gondii virulence

The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites

The ROP2 family of Toxoplasma gondii rhoptry proteins: proteomic and genomic characterization and molecular modeling

The Toxoplasma gondii protein MIC3 requires pro-peptide cleavage and dimerization to function as adhesin

The moving junction of apicomplexan parasites: a key structure for invasion

The rhoptry neck protein RON4 re-localizes at the moving junction during Toxoplasma gondii invasion

The role played by electron microscopy in advancing our understanding of Toxoplasma gondii and other apicomplexans

Towards a molecular architecture of the centrosome in Toxoplasma gondii

Toxoplasma gondii grown in human cells uses GalNAc-containing glycosylphosphatidylinositol precursors to anchor surface antigens while the immunogenic Glc-GalNAc-containing precursors remain free at the parasite cell surface

Toxoplasma gondii secretory proteins bind to sulfated heparin structures

Toxoplasma gondii uses unusual sorting mechanisms to deliver transmembrane proteins into the host-cell vacuole

Transient infection of the zebrafish notochord with E. coli induces chronic inflammation

Virulence factors of Toxoplasma gondii

Virulent and avirulent strains of Toxoplasma gondii which differ in their glycosylphosphatidylinositol content induce similar biological functions in macrophages.

Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cells