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List of works by Jean-Claude Guillemot

A fluorescence-based high throughput-screening assay for the SARS-CoV RNA synthesis complex

scientific article published on 06 November 2020

A relaxed discrimination of 2'-O-methyl-GTP relative to GTP between de novo and Elongative RNA synthesis by the hepatitis C RNA-dependent RNA polymerase NS5B.

scientific article published on 22 November 2004

A second, non-canonical RNA-dependent RNA polymerase in SARS Coronavirus

scientific article

Alkylated flavanones from the bark of Cryptocarya chartacea as dengue virus NS5 polymerase inhibitors

scientific article published on 3 November 2011

Antiviral Compounds from Codiaeum peltatum Targeted by a Multi-informative Molecular Networks Approach

scientific article published on 25 January 2019

Antiviral chlorinated daphnane diterpenoid orthoesters from the bark and wood of Trigonostemon cherrieri

scientific article published on 29 August 2012

Approved drugs screening against the nsP1 capping enzyme of Venezuelan equine encephalitis virus using an immuno-based assay

scientific article published on 11 January 2019

Betulinic Acid, The First Lupane-Type Triterpenoid Isolated from Both a Phomopsis sp. and Its Host Plant Diospyros carbonaria Benoist.

scientific article published on 27 August 2016

Biflavonoids of Dacrydium balansae with potent inhibitory activity on dengue 2 NS5 polymerase

scientific article published on 12 March 2012

Biodiversity as a Source of Potent and Selective Inhibitors of Chikungunya Virus Replication

Carneic Acids from an Endophytic Phomopsis sp. as Dengue Virus Polymerase Inhibitors ⬇️

scientific article published on 20 July 2020

Chemical constituents of Anacolosa pervilleana and their antiviral activities

scientific article published on 14 May 2012

Chemical diversity and antiviral potential in the pantropical Diospyros genus.

scientific article published on 25 April 2016

Comparative Virtual and Experimental Medium Throughput Screening for Hepatitis C Virus Polymerase Inhibitors

article published in 2008

Comparative mechanistic studies of de novo RNA synthesis by flavivirus RNA-dependent RNA polymerases.

scientific article

Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes

scientific article

Dengue virus replicons: production of an interserotypic chimera and cell lines from different species, and establishment of a cell-based fluorescent assay to screen inhibitors, validated by the evaluation of ribavirin's activity

scientific article published on 20 March 2010

Drugs against SARS-CoV-2: What do we know about their mode of action?

scientific article published on 11 August 2020

Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins

scientific article

Flacourtosides A-F, phenolic glycosides isolated from Flacourtia ramontchi

scientific article published on 22 March 2012

Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors

scientific article published on 01 June 2018

Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step

scientific article

Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16.

scientific article

Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase

scientific article published on 29 December 2015

PHYTOCHIK: Biodiversity As A Source of Selective Inhibitors of CHIKV Replication

article published in 2011

Protein-Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery

scientific article

Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites

scientific article published on 10 April 2020

Simeprevir potently suppresses SARS-CoV-2 replication and synergizes with remdesivir

scientific article published on 26 May 2020

Structure-activity relationship study of biflavonoids on the Dengue virus polymerase DENV-NS5 RdRp

scientific article published on 8 August 2013

The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding protein

scientific article published on 5 February 2008

The Zika virus methyltransferase: structure and functions for drug design perspectives

scientific article (publication date: 28 December 2016)

The flavivirus polymerase as a target for drug discovery.

scientific article published on 09 July 2008

Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

scientific article published on July 2017

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