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List of works by Alejandro Losada

Abstract 5467: Role of the eukaryotic elongation factor eEF1A in the mechanism of action of Aplidin

Antitumor actinopyranones produced by Streptomyces albus POR-04-15-053 isolated from a marine sediment.

scientific article published on 30 June 2011

Aplidin induces apoptosis in human cancer cells via glutathione depletion and sustained activation of the epidermal growth factor receptor, Src, JNK, and p38 MAPK.

scientific article published on 31 October 2002

Aplidin induces the mitochondrial apoptotic pathway via oxidative stress-mediated JNK and p38 activation and protein kinase C delta

scientific article published on 01 October 2002

Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival

scientific article published on 13 November 2018

Dynamic cellular maps of molecular species: Application to drug-target interactions

scientific article

Generation of endoplasmic reticulum stress and inhibition of autophagy by plitidepsin induces proteotoxic apoptosis in cancer cells

scientific article published on 06 December 2019

Gracilins G-I, Cytotoxic Bisnorditerpenes from Spongionella pulchella, and the Anti-Adhesive Properties of Gracilin B

The mechanism of action of plitidepsin.

scientific article published on June 2009

Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin.

scientific article published on 7 October 2016

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