List of works - Thomas M Kündig

A Protective Allergy Vaccine Based on CpG- and Protamine-Containing PLGA Microparticles

scientific article published on 31 May 2007

A VLP-based vaccine against interleukin-1α protects mice from atherosclerosis

scientific article published on 28 January 2013

A cutaneous allergen neutralisation test that correlates with the duration of venom immunotherapy

scientific article published on 30 August 2006

A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control

scientific article published on 15 January 2020

A major allergen gene-fusion protein for potential usage in allergen-specific immunotherapy

scientific article published in February 2005

A molecular assembly system that renders antigens of choice highly repetitive for induction of protective B cell responses

scientific article

A randomized, double-blind, placebo-controlled study to test the efficacy of topical 2-hydroxypropyl-Beta-cyclodextrin in the prophylaxis of recurrent herpes labialis

scientific article published on 25 June 2013

A virus-like particle-based vaccine selectively targeting soluble TNF-alpha protects from arthritis without inducing reactivation of latent tuberculosis

scientific article

Active vaccination against Interleukin-5 as long-term treatment for insect bite hypersensitivity in horses

scientific article published on 25 November 2018

Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems

article

Allergen immunotherapy in allergic rhinitis: current use and future trends

scientific article published on 23 May 2017

Allergen-specific immunotherapy: regulatory T cells or allergen-specific IgG?

scientific article published on 01 August 2010

Antigen kinetics determines immune reactivity

scholarly article

Apremilast in Treatment-Refractory Recurrent Aphthous Stomatitis

scientific article published on 01 November 2019

Atopic eczema: genetics or environment?

scientific article

Clemastine causes immune suppression through inhibition of extracellular signal-regulated kinase–dependent proinflammatory cytokines ⬇️

scientific article published on July 31, 2011

Clinical Disease Patterns in a Regional Swiss Cohort of 34 Pyoderma Gangrenosum Patients.

scientific article published on 7 November 2017

Combined Photosensitization and Vaccination Enable CD8 T-Cell Immunity and Tumor Suppression Independent of CD4 T-Cell Help

scientific article published on 05 July 2019

Comparing safety of abrasion and tape-stripping as skin preparation in allergen-specific epicutaneous immunotherapy

scientific article published in October 2014

Comparison of microneedles and adhesive-tape stripping in skin preparation for epicutaneous allergen delivery

scientific article published on 12 August 2015

Correction to: Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

scientific article published on 23 May 2019

CpG oligodeoxynucleotides block human immunodeficiency virus type 1 replication in human lymphoid tissue infected ex vivo

scientific article

Critical role for DNA vaccination frequency in induction of antigen-specific cytotoxic responses

scientific article published on 19 September 2005

Critical role for activation of antigen-presenting cells in priming of cytotoxic T cell responses after vaccination with virus-like particles

scientific article published on March 2002

Cutaneous Corynebacterium Infection Presenting with Disseminated Skin Nodules and Ulceration.

scientific article published on 16 May 2017

Der p 1 peptide on virus-like particles is safe and highly immunogenic in healthy adults

scientific article published on 27 April 2006

Distinct T helper cell dependence of memory B-cell proliferation versus plasma cell differentiation.

scientific article published on 9 November 2016

Encapsulation of antigen in poly(d,l-lactide-co-glycolide) microspheres protects from harmful effects of γ-irradiation as assessed in mice ⬇️

scientific article published on October 18, 2011

Enhancing DNA vaccination by sequential injection of lymph nodes with plasmid vectors and peptides

scientific article

Epicutaneous Immunotherapy for Aeroallergen and Food Allergy

scientific article published on 17 December 2013

Epicutaneous allergen administration as a novel method of allergen-specific immunotherapy

scientific article published on 5 September 2009

Epicutaneous allergen-specific immunotherapy ameliorates grass pollen-induced rhinoconjunctivitis: A double-blind, placebo-controlled dose escalation study ⬇️

scientific article published on October 13, 2011

Epicutaneous/transcutaneous allergen-specific immunotherapy: rationale and clinical trials ⬇️

scientific article published on December 1, 2010

Evaluation of visual analog scales for the assessment of symptom severity in allergic rhinoconjunctivitis

scientific article published in February 2007

Fucosyltransferase VII-deficient mice with defective E-, P-, and L-selectin ligands show impaired CD4+ and CD8+ T cell migration into the skin, but normal extravasation into visceral organs

scientific article published in March 2002

HIV-specific cellular immune response is inversely correlated with disease progression as defined by decline of CD4+ T cells in relation to HIV RNA load

scientific article published on 17 March 2004

Heat denaturation, a simple method to improve the immunotherapeutic potential of allergens

scientific article published on 01 December 2005

IL-12 protects from psoriasiform skin inflammation

scientific article

Immunity in response to particulate antigen-delivery systems

scientific article

Immunization of Cats against Fel d 1 Results in Reduced Allergic Symptoms of Owners

scientific article published on 06 March 2020

Immunization of cats to induce neutralizing antibodies against Fel d 1, the major feline allergen in human subjects

scientific article published on 02 May 2019

Immunotherapeutic targeting of allergic disease

scientific article published on December 2006

Immunotherapy of type-1 allergies with virus-like particles and CpG-motifs

scientific article

Improving the therapeutic index of CpG oligodeoxynucleotides by intralymphatic administration

scientific article published on 01 June 2005

Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression

scientific article published on 17 October 2011

Interleukin 31 in insect bite hypersensitivity-Alleviating clinical symptoms by active vaccination against itch

scientific article published on 09 December 2019

Intradermal photosensitisation facilitates stimulation of MHC class-I restricted CD8 T-cell responses of co-administered antigen

scientific article published on 23 November 2013

Intralymphatic Immunotherapy: From the Rationale to Human Applications ⬇️

scientific article published on January 1, 2011

Intralymphatic Immunotherapy: Update and Unmet Needs

scientific article published on 02 November 2018

Intralymphatic allergen administration renders specific immunotherapy faster and safer: a randomized controlled trial

scholarly article

Intralymphatic immunotherapy

scientific article

Intralymphatic immunotherapy

scientific article published on 01 December 2009

Intralymphatic immunotherapy and vaccination in mice

scientific article

Intralymphatic immunotherapy for cat allergy induces tolerance after only 3 injections

scientific article published on 30 March 2012

Intralymphatic immunotherapy: time interval between injections is essential

scientific article published on 15 January 2014

Intralymphatic injections as a new administration route for allergen-specific immunotherapy

scientific article published on 2 April 2009

Intraperitoneal administration of aluminium-based adjuvants produces severe transient systemic adverse events in mice

scientific article published on 2 February 2018

Is The Allergen Really Needed in Allergy Immunotherapy?

scientific article published on January 2015

Low-affinity B cells transport viral particles from the lung to the spleen to initiate antibody responses

scientific article

Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis

scientific article

Lymph node-targeted immunotherapy mediates potent immunity resulting in regression of isolated or metastatic human papillomavirus-transformed tumors.

scientific article published on 29 September 2009

Lympho-geographical concepts in vaccine delivery

scientific article published on 23 May 2010

Mechanisms of allergen-specific desensitization

scientific article published on 10 July 2010

Memory and effector CD8 T-cell responses after nanoparticle vaccination of melanoma patients

scientific article

Microcrystalline Tyrosine and Aluminum as Adjuvants in Allergen-Specific Immunotherapy Protect from IgE-Mediated Reactivity in Mouse Models and Act Independently of Inflammasome and TLR Signaling.

scientific article published on 28 March 2018

Modular antigen-translocation as a novel vaccine strategy for allergen-specific immunotherapy.

scientific article

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8⁺ T-cell responses in melanoma patients

scientific article published on 28 August 2012

New routes for allergen immunotherapy

scientific article published on October 2012

Nickel sensitisation in mice: a critical appraisal

scientific article published on 23 March 2010

Novel Administration Routes for Allergen-Specific Immunotherapy: A Review of Intralymphatic and Epicutaneous Allergen-Specific Immunotherapy ⬇️

scientific article published on May 1, 2011

Novel Delivery Routes for Allergy Immunotherapy: Intralymphatic, Epicutaneous, and Intradermal

scientific article

Oncolytic measles virus in cutaneous T-cell lymphomas mounts antitumor immune responses in vivo and targets interferon-resistant tumor cells

scientific article published on 16 June 2005

Photochemical Internalization: Light Paves Way for New Cancer Chemotherapies and Vaccines

scientific article published on 09 January 2020

Photochemical targeting of antigens to the cytosol for stimulation of MHC class-I-restricted T-cell responses

scientific article published on 24 February 2013

Photosensitisation facilitates cross-priming of adjuvant-free protein vaccines and stimulation of tumour-suppressing CD8 T cells

scientific article published on 4 December 2014

Photosensitizer and Light Pave the Way for Cytosolic Targeting and Generation of Cytosolic CD8 T Cells Using PLGA Vaccine Particles

scientific article published on 27 May 2015

Prevention of allergy by a recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes

scientific article

Proliferation of CD30+ T-helper 2 lymphoma cells can be inhibited by CD30 receptor cross-linking with recombinant CD30 ligand.

scientific article

Relief from Zmp1-mediated arrest of phagosome maturation is associated with facilitated presentation and enhanced immunogenicity of mycobacterial antigens.

scientific article

Risk Assessment of Hymenoptera Re-Sting Frequency: Implications for Decision-Making in Venom Immunotherapy ⬇️

scientific article published on January 1, 2013

Safety Profile of a Virus-Like Particle-Based Vaccine Targeting Self-Protein Interleukin-5 in Horses

scientific article published on 09 May 2020

Shaping Modern Vaccines: Adjuvant Systems Using MicroCrystalline Tyrosine (MCT<sup>®</sup>)

scientific article published on 24 November 2020

Skin lesions in anti-Pm-Scl-70 positive systemic sclerosis-dermatomyositis overlap syndrome improve during local PUVA phototherapy

scientific article published in September 2013

Surface coating of PLGA microparticles with protamine enhances their immunological performance through facilitated phagocytosis.

scientific article

TLR4- and TRIF-dependent stimulation of B lymphocytes by peptide liposomes enables T cell-independent isotype switch in mice ⬇️

scientific article published on November 8, 2012

Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine.

scientific article published on 15 May 2019

The antihistamines clemastine and desloratadine inhibit STAT3 and c‐Myc activities and induce apoptosis in cutaneous T‐cell lymphoma cell lines ⬇️

scientific article published on February 1, 2013

The use of anti-T-cell receptor-Vbeta antibodies for the estimation of treatment success and phenotypic characterization of clonal T-cell populations in cutaneous T-cell lymphomas

scientific article published on 01 September 2002

Treating insect-bite hypersensitivity in horses with active vaccination against IL-5.

scientific article published on 28 March 2018

Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology

scientific article published on 29 September 2008

Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

scientific article published on 26 April 2019

Vaccine against peanut allergy based on engineered virus-like particles displaying single major peanut allergens

scientific article published on 19 December 2019

Viral particles drive rapid differentiation of memory B cells into secondary plasma cells producing increased levels of antibodies

scientific article published on 12 May 2014

Virus-induced humoral immunity: on how B cell responses are initiated

scientific article published on June 2013

Virus-like particles (VLP) in prophylaxis and immunotherapy of allergic diseases.

scientific article published on 9 July 2018

[Transcutaneous applications for vaccination and immunotherapy]

scientific article published on 01 October 2014

List of works by Thomas M Kündig

A Protective Allergy Vaccine Based on CpG- and Protamine-Containing PLGA Microparticles

A Protective Allergy Vaccine Based on CpG- and Protamine-Containing PLGA Microparticles

A VLP-based vaccine against interleukin-1α protects mice from atherosclerosis

A cutaneous allergen neutralisation test that correlates with the duration of venom immunotherapy

A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control

A major allergen gene-fusion protein for potential usage in allergen-specific immunotherapy

A molecular assembly system that renders antigens of choice highly repetitive for induction of protective B cell responses

A randomized, double-blind, placebo-controlled study to test the efficacy of topical 2-hydroxypropyl-Beta-cyclodextrin in the prophylaxis of recurrent herpes labialis

A virus-like particle-based vaccine selectively targeting soluble TNF-alpha protects from arthritis without inducing reactivation of latent tuberculosis

Active vaccination against Interleukin-5 as long-term treatment for insect bite hypersensitivity in horses

Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems

Allergen immunotherapy in allergic rhinitis: current use and future trends

Allergen-specific immunotherapy: regulatory T cells or allergen-specific IgG?

Antigen kinetics determines immune reactivity

Apremilast in Treatment-Refractory Recurrent Aphthous Stomatitis

Atopic eczema: genetics or environment?

Clemastine causes immune suppression through inhibition of extracellular signal-regulated kinase–dependent proinflammatory cytokines ⬇️

Clinical Disease Patterns in a Regional Swiss Cohort of 34 Pyoderma Gangrenosum Patients.

Combined Photosensitization and Vaccination Enable CD8 T-Cell Immunity and Tumor Suppression Independent of CD4 T-Cell Help

Comparing safety of abrasion and tape-stripping as skin preparation in allergen-specific epicutaneous immunotherapy

Comparison of microneedles and adhesive-tape stripping in skin preparation for epicutaneous allergen delivery

Correction to: Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

CpG oligodeoxynucleotides block human immunodeficiency virus type 1 replication in human lymphoid tissue infected ex vivo

Critical role for DNA vaccination frequency in induction of antigen-specific cytotoxic responses

Critical role for activation of antigen-presenting cells in priming of cytotoxic T cell responses after vaccination with virus-like particles

Cutaneous Corynebacterium Infection Presenting with Disseminated Skin Nodules and Ulceration.

Der p 1 peptide on virus-like particles is safe and highly immunogenic in healthy adults

Distinct T helper cell dependence of memory B-cell proliferation versus plasma cell differentiation.

Encapsulation of antigen in poly(d,l-lactide-co-glycolide) microspheres protects from harmful effects of γ-irradiation as assessed in mice ⬇️

Enhancing DNA vaccination by sequential injection of lymph nodes with plasmid vectors and peptides

Epicutaneous Immunotherapy for Aeroallergen and Food Allergy

Epicutaneous allergen administration as a novel method of allergen-specific immunotherapy

Epicutaneous allergen-specific immunotherapy ameliorates grass pollen-induced rhinoconjunctivitis: A double-blind, placebo-controlled dose escalation study ⬇️

Epicutaneous/transcutaneous allergen-specific immunotherapy: rationale and clinical trials ⬇️

Evaluation of visual analog scales for the assessment of symptom severity in allergic rhinoconjunctivitis

Fucosyltransferase VII-deficient mice with defective E-, P-, and L-selectin ligands show impaired CD4+ and CD8+ T cell migration into the skin, but normal extravasation into visceral organs

HIV-specific cellular immune response is inversely correlated with disease progression as defined by decline of CD4+ T cells in relation to HIV RNA load

Heat denaturation, a simple method to improve the immunotherapeutic potential of allergens

IL-12 protects from psoriasiform skin inflammation

Immunity in response to particulate antigen-delivery systems

Immunization of Cats against Fel d 1 Results in Reduced Allergic Symptoms of Owners

Immunization of cats to induce neutralizing antibodies against Fel d 1, the major feline allergen in human subjects

Immunotherapeutic targeting of allergic disease

Immunotherapy of type-1 allergies with virus-like particles and CpG-motifs

Improving the therapeutic index of CpG oligodeoxynucleotides by intralymphatic administration

Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression

Interleukin 31 in insect bite hypersensitivity-Alleviating clinical symptoms by active vaccination against itch

Intradermal photosensitisation facilitates stimulation of MHC class-I restricted CD8 T-cell responses of co-administered antigen

Intralymphatic Immunotherapy: From the Rationale to Human Applications ⬇️

Intralymphatic Immunotherapy: Update and Unmet Needs

Intralymphatic allergen administration renders specific immunotherapy faster and safer: a randomized controlled trial

Intralymphatic immunotherapy

Intralymphatic immunotherapy

Intralymphatic immunotherapy and vaccination in mice

Intralymphatic immunotherapy for cat allergy induces tolerance after only 3 injections

Intralymphatic immunotherapy: time interval between injections is essential

Intralymphatic injections as a new administration route for allergen-specific immunotherapy

Intraperitoneal administration of aluminium-based adjuvants produces severe transient systemic adverse events in mice

Is The Allergen Really Needed in Allergy Immunotherapy?

Low-affinity B cells transport viral particles from the lung to the spleen to initiate antibody responses

Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis

Lymph node-targeted immunotherapy mediates potent immunity resulting in regression of isolated or metastatic human papillomavirus-transformed tumors.

Lympho-geographical concepts in vaccine delivery

Mechanisms of allergen-specific desensitization

Memory and effector CD8 T-cell responses after nanoparticle vaccination of melanoma patients

Microcrystalline Tyrosine and Aluminum as Adjuvants in Allergen-Specific Immunotherapy Protect from IgE-Mediated Reactivity in Mouse Models and Act Independently of Inflammasome and TLR Signaling.

Modular antigen-translocation as a novel vaccine strategy for allergen-specific immunotherapy.

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8⁺ T-cell responses in melanoma patients

New routes for allergen immunotherapy

Nickel sensitisation in mice: a critical appraisal

Novel Administration Routes for Allergen-Specific Immunotherapy: A Review of Intralymphatic and Epicutaneous Allergen-Specific Immunotherapy ⬇️

Novel Delivery Routes for Allergy Immunotherapy: Intralymphatic, Epicutaneous, and Intradermal

Oncolytic measles virus in cutaneous T-cell lymphomas mounts antitumor immune responses in vivo and targets interferon-resistant tumor cells

Photochemical Internalization: Light Paves Way for New Cancer Chemotherapies and Vaccines

Photochemical targeting of antigens to the cytosol for stimulation of MHC class-I-restricted T-cell responses

Photosensitisation facilitates cross-priming of adjuvant-free protein vaccines and stimulation of tumour-suppressing CD8 T cells

Photosensitizer and Light Pave the Way for Cytosolic Targeting and Generation of Cytosolic CD8 T Cells Using PLGA Vaccine Particles

Prevention of allergy by a recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes

Proliferation of CD30+ T-helper 2 lymphoma cells can be inhibited by CD30 receptor cross-linking with recombinant CD30 ligand.